Ɔltin we yu nid fɔ no bɔt di ALP valyu na yu blɔd ripɔt (Alkaline Phosphatase - ALP) .

Yu dɔn ɛva du blɔd tɛst, pik di ripɔt, luk di lɛta ɛn nɔmba dɛn we de pan am, ɛn tink se, "Wetin na dis?" Pan di bɔku lɛta dɛn lɛk ALT, AST, ɛn GGT, yu go dɔn si wan valyu bak we dɛn kɔl "ALP." Bɔku pipul dɛn kin wɔri smɔl we dɛn si dis. So, tide wi go tɔk bɔt wetin dis Alkaline Phosphatase, ɔ ALP fɔ shɔt, bi, wetin i de luk fɔ na dis tɛst, ɛn wetin wi nid fɔ no we in valyu dɛn chenj.

Wetin na ALP rili?

Fɔ tɔk am simpul wan, Alkaline Phosphatase (ALP) na wan ɛnzaym we de ɔlsay na wi bɔdi. Enzym na wan spɛshal kayn prɔtin we de insay wi sɛl dɛn. Lɛk mashin we de spid na faktri, dɛn ɛnzaym dɛn ya de ɛp ɛn mek difrɛn kayn kemikal dɛn we de na wi bɔdi kwik kwik wan. Bɔku bɔku pan dɛn ɛnzaym ya de na wi bɔdi.

Pan ɔl we dɔktɔ dɛn dɔn de du risach bɔt ALP fɔ lɔng tɛm, dɛn stil nɔ no 100% fɔ shɔ wetin na in ɛksaktɔl wok. Bɔt dɛn dɔn si se i de insay bɔku impɔtant tin dɛn we de apin na di bɔdi.

we dεn de tכk bכt ALP, dεn kin kכl am "liva εnzym." Di rizin fɔ dis na bikɔs ALP kin de mɔ na wi liva. Bɔt nɔto jɔs di liva nɔmɔ i de du. Dɛn kin si am na ɔda say dɛn bak.

• yu bayl dakt dεm: Tiub dεm we de kכri bayl we di liva de mek to di gal blad, usay i de stכr.
• Insay yu bon dɛn: Dat min se na yu bon dɛn.
• Na di kidni dɛn.
• Intestinal dɛn.
• Plasεnta fכ mama dεm we gεt bεlε.

So, if di ALP lεvεl na yu bכdi nכmכl כ lכw, na sayn fכ sכm damej כ chenj na sכm prכsεs na wan pan dεn כgan dεm ya.

Wetin na ALP blɔd tɛst?

ALP blɔd tɛst de mɛzhɔ di ALP we de na yu blɔd. As wi bin dɔn tɔk, pan ɔl we ALP de ɔlsay na di bɔdi, di tu men tin dɛn we de mek ALP kin gɛda na di blɔd na di liva ɛn di bon dɛn. So, if di ALP lɛvɛl na di blɔd go ɔp, i kin bi sayn fɔ liva sik ɔ sɔm bon sik. Bɔt mɛmba se, ALP tɛst nɔmɔ nɔ go ebul fɔ no if pɔsin gɛt sik.

Tu men kayn ALP tɛst dɛn de.

1. Rutin ALP tεst: Dis na di tεst we dεn kin du mכst. כltεm, if dכkta aks yu fכ du `Kכmprεhεnsiv Mεtabolik Panεl (CMP)` כ wan `Liva Panεl (LFT)`, we de luk di liva, i go fכs inklud di ALP valyu.

2. ALP isoɛnzym tɛst: .Dis na smɔl spɛshal tɛst. Di ALP tɛst we dɛn kin du ɔltɛm kin jɔs tɛl yu ɔmɔs ALP de na yu blɔd. Bɔt dis isoɛnzym tɛst kin tɛl yu ɛksaktɔli if di ALP we pasmak na yu blɔd de kɔmɔt na yu liva, bon, ɔ ɔdasay. If yu ALP lɛvɛl rili ay, yu dɔktɔ kin ɔda dis tɛst fɔ no di rayt kɔz. Bɔt i kɔmplikt smɔl ɛn i dia, so nɔto ɔl lab dɛn kin du am.

Wetin mek wi nid dis ALP tɛst?

Bɔku rizin dɛn kin de we mek yu dɔktɔ go ɔda fɔ mek dɛn du ALP tɛst.

• Skrin: Sɔntɛnde, ivin if nɔr simptom nɔ de, dɛn kin chɛk ALP as pat pan yu rutin ɛni ia chɛk-ap CMP ɔ LFT ripɔt fɔ gɛt clue bɔt prɔblɛm na di liva ɔ ɔdasay bifo di simptom dɛn apia.
• Fɔ wach: If yu dɔn ɔlrɛdi gɛt liva ɔ bon sik, dɛn kin yuz dis tɛst bak fɔ wach if di sik de bɛtɛ, de di sem, ɔr de wɔs wit tritmɛnt.
• As ɛp fɔ no di sik: If yu gɛt sɔm kayn sik wae gɛt fɔ du wit liva ɔ bon sik, ALP tɛst na impɔtant pat pan di diagnosis prɔses.

Simptom dɛm wae kin mek dɔktɔ tink bɔt fɔ du ALP tɛst

If yu gɛt di sayn dɛm we de dɔŋ ya, yu dɔktɔ kin rifer yu fɔ dis tɛst.

Wetin kin apin bifo ɛn we dɛn de du di blɔd tɛst?

If yu dɔktɔ tɛl yu fɔ du dis ALP tɛst as pat pan CMP, yu go nid fɔ fast fɔ lɛk 10-12 awa. Bɔt yu kin drink wata. Bɔt we dɛn aks yu fɔ du blɔd tɛst, yu dɔktɔ go gi yu patikyula tin dɛn fɔ du bifo dɛn du am. I rili impɔtant fɔ fala dɛn instrɔkshɔn dɛn de.

Na dɛn tin ya kin apin we dɛn pul blɔd.

1. Yu go sidɔm na chia, ɛn nɔs ɔ mɛdikal ɔfisa go fɛn wan fayn vein na yu an fɔ pul blɔd frɔm. Dis kin de insay yu ɛlb.

2. Afta yu dɔn fɛn di vein, klin di say fayn fayn wan wit sɔntin lɛk fɔ rɔb rɔb.

3. Dɔn, dɛn kin put smɔl nidul insay di vein ɛn tek blɔd sɛmpul. Dis tɛm ya, yu kin fil smɔl sting, lɛk smɔl ant we de sting yu.

4. Afta yu dɔn gɛda di blɔd we yu nid fɔ di tɛst insay wan tiub, pul di nidul ɛn pres di say we dɛn tek di blɔd wit wan kɔtɔn.

5. We di blɔd dɔn stɔp, dɛn kin put smɔl plasta na di say ɛn dɛn kin dɔn di wok.

Di wan ol tin we dɛn kin du nɔ kin tek fayv minit. Sɔm smɔl pen ɛn brus kin de usay dɛn pul di blɔd. Bɔt dat go dɔn insay wan ɔ tu dez.

Aw yu ɔndastand wetin de insay di ripɔt?

Bɔku tɛm, yu kin gɛt di ripɔt insay wan ɔ tu dez. Di ripɔt gɛt tin dɛn lɛk dis:

• Nem fɔ di tɛst (e.g. Alkaline Phosphatase).
• Yu rizulyt (di ALP valyu na yu blɔd).
• Nɔmal rɛnj.
• Ilɛksɛf yu valyu nɔmal, ay, ɔ smɔl.

wan jεnarali aksepted rεnj na 44 to 147 intanashɔnal yunit dεm pan wan lita (44 to 147 IU/L). Bɔt na sɔm say dɛn dɛn kin tek dis bak as 30 to 120 IU/L.

כlso, di nכmal ALP valyu dεm de difrεn dipכnt pan di ej εn jεnda.

• Pikin ɛn yɔŋ pipul dɛn: Pikin ɛn yɔŋ pipul dɛn gɛt natura l ay ALP lɛvɛl bikɔs dɛn bon dɛn de gro.
• Bitwin di ej 15-50: Man dεm gεt sכm hכy ALP lεvεl pas uman dεm.
• We wi de ol: di ALP lεvεl de go כp sכmtεm bak as wi de ol.
• we uman bεlε: i kכmכn fכ mama dεm we bεlε fכ gεt εlevεt ALP lεvεl biכs ALP de prodyuz insay di plasεnta.
• we bon fraktכs hεl: We bon brok, di ALP lεvεl kin inkrεs as di bon sεl dεm de wok as i de hεl.

Wetin inkris pan ALP min?

If yu ALP lɛvɛl dɔn go ɔp, na nɔmal tin fɔ fil fɔ wɔri smɔl. Bɔt di fɔs tin fɔ mɛmba na dat, if di ALP lɛvɛl go ɔp smɔl nɔ kin bi sayn fɔ siriɔs sik ɔltɛm. Yu dɔktɔ kin disayd nɔ fɔ du ɛni ɔda tɛst ɛn jɔs de wach yu ALP lɛvɛl bak insay smɔl tɛm.

כltu, we di ALP lεvεl rili h כy na strכng indikεshכn fכ liva dεm dεm כ bon sik. If yu ripɔt se ALP dɔn go ɔp, yu dɔktɔ kin ɔda fɔ du ɔda tɛst (e.g., isoɛnzyme tɛst, liva skan) fɔ no di kɔz.

Di men rizin dɛn we mek ALP kin bɔku, dɛn kin sheb dɛn to tu kategori.

Kɔz dɛm we gɛt fɔ du wit di liva ɛn di bayl dakt dɛm

• Cholestasis of pregnancy: Na di liva kכndyushכn we kin apin di las pat pan di bεlε.
• Sirosis na di liva: di liva de damej fɔ ɔltɛm we di liva sɛl dɛn day ɛn ska tisu de tek in ples.
• Epataytis: Na inflamɛns na di liva. Dis kin kam bikɔs ɔf vayrɔs, rɔm, ɔ ɔda tin.
• di bayl dakt obstrukshכn: di dakt we de kכri bayl frכm di liva de blok bikoz fכ gal ston, kansa tכmכro, כ כda tin dεm.
• Mononucleosis: dεn kכl am bak "kissing disease," dis vayral infεkshכn kin mek di liva swel sכmtεm.

Bɔn (skel) rilayt kɔz dɛm

• Paget’s disease of the bone: Na wan kayn tin we nɔ kin apin so ɔltɛm we di bon dɛn kin brok ɛn gro bak we nɔrmal.
• Osteogenic sarcoma: Na wan kayn kansa we kin bigin na di bon dɛm.
• Bɔn mɛtastasis: Kansa we kɔmɔt na ɔda say lɛk di bɔdi ɔ di lɔng, kin go na di bon dɛn.
• haypaparatayroydism: di kalsiכm lεvεl dεm na di bכdi de inkrεs bikoz di paratayroyd gland de kכl כmon dεm pasmak.
• Hyperthyroidism: Na di tayroyd gland de mek ɔmon dɛn pasmak.
• Osteomalacia: Na kכndyushכn we di bon dεm kin wik εn brok izi wan biכs fכ di vaytamεn D we dεn nכ gεt. We dis kin apin to pikin dɛn, wi kin kɔl am Rikɛt.
• Wan fraktrɔs we de mɛn.

Wetin na di poshubul tin dɛm we kin mek di ALP lɛvɛl smɔl?

i rili rare fכ di ALP lεvεl dεm fכ abnכmal lכw, bכt sεvεra poshubul rizin dεm de fכ dis.

• Malnutrishɔn: Nɔ gɛt di tin dɛn we di bɔdi nid fɔ it.
• Zink we nɔ gɛt bɛtɛ tin fɔ it.
• Magnesium we nɔ de wok fayn.
• Hypothyroidism: Di tayroyd gland de wok fayn fayn wan.
• Sik dεm we nכ kin gεt jεnεtik: Na dεn kכndyushכn dεm we nכ kin bכku lεk `Hypophosphatasia` εn `Wilson disease`.

A fɔ wɔri if mi ALP lɛvɛl ay ɔ smɔl?

Na lɛk wan pan ɛvri 20 pipul dɛn we gɛt wɛlbɔdi kin gɛt tɛst rizɔlt we nɔ de na di nɔmal rɛnj. Ɔda tin dɛn kin afɛkt di ALP valyu dɛn bak.

• Sɔm mɛrɛsin dɛn: Sɔm mɛrɛsin dɛn, lɛk pils fɔ kɔntrol bɔn pikin.
• Di it we yu de it.
• We uman gɛt bɛlɛ.
• Ej: As wi bin dɔn tɔk, di valyu fɔ pikin dɛn we de gro bɔku.
• Wan mistek we kin apin we dɛn de gɛda, transpɔt, ɔ tɛst di blɔd sɛmpul.

So, yu dɔktɔ nɔ go ɛva disayd fɔ du sɔntin bay di ALP valyu nɔmɔ. I go tɔk bɔt ɔl dɛn tin ya:

• Yu kɔmplit mɛdikal istri.
• Us mɛrɛsin yu de tek naw?
• Aw yu ALP valyu ay ɔ smɔl.
• Rizult fכ כda tεst dεm we dεn chεk wit ALP (e.g. ALT, GGT, Bilirubin).
• Yu gɛt ɛni sayn fɔ sho se yu gɛt dis sik?

If yu put ɔl dis togɛda, dat go mek yu no if yu nid fɔ du mɔ tɛst ɔ tritmɛnt.