Yu dɔn du blɔd tɛst i nɔ tu te yet? We yu si di ALP valyu bitwin di lɛta ɛn nɔmba dɛn, yu go dɔn tink se, ‘Wetin na dis?’ Nɔ wɔri, bɔku pipul dɛn kin fil di sem we. Na nɔmal tin. Tide, lɛ wi tɔk bɔt wetin na dis ALP tɛst, wetin mek dɔktɔ dɛn kin chɛk am, ɛn wetin chenj dɛn na in valyu rili se bɔt wi wɛlbɔdi.
Fɔs, lɛ wi si, wetin na alkaline phosphatase (ALP)?
Fɔ tɔk am simpul wan, alkaline phosphatase, ɔ ALP as wi de tɔk bɔt, na ɛnzaym na wi bɔdi. I tan lɛk smɔl wokman insay wi bɔdi. Dis wokman kin de mɔ na wi liva ɛn bon dɛn . pan tap dat, sכm sכm tin dεm de fכn na wi dijestiv sistεm, kidni dεm, εn ivin di plasεnta we wi bεlε.
pan ɔl we sayɛnsman dɛn stil nɔ shɔ 100%, dɛn biliv se dis ALP ɛnzaym de du bɔku impɔtant wok dɛn na wi bɔdi. fכ egzampl, ALP de εp fכ bil strכng tisu dεm lεk bon dεm εn tit dεm, εn i de εp fכ muv tin dεm lεk fכsfεt rawnd insay di intestinal dεm.
Di rilayshɔn bitwin fat liva ɛn ALP
ALP na wan mak we dɛn kin yuz fɔ no if pɔsin gɛt fat liva sik. Bɔt nɔto di wangren mak we go ebul fɔ no di sik. Tu men kayn fat liva sik de:
- Metabolic-associated steatotic liver disease (MASLD): Dis kin kam bikɔs di fat we de bɔku na di liva bikɔs ɔf tin dɛn lɛk ay kɔlɔstrel, tayp 2 dayabitis, insulin rɛsistɛns, ɔ bɔdi mas indeks (BMI) we pas 30.
- Alcoholic fatty liver disease: As di nem sho, dis kin kam bikɔs yu de drink tumɔs rɔm fɔ lɔng tɛm.
Dɔktɔ, wetin mek yu de aks mi fɔ du ALP tɛst?
Bɔku rizin dɛn de we mek yu dɔktɔ kin ɔda fɔ mek dɛn du ALP tɛst. Bɔrku tɛm, dɛn kin du dis fɔ no if yu gɛt liva we dɔn pwɛl ɔ yu gɛt bon sik.
sכmtεm, dεn kin inklud dis ALP tεst as pat pan di ``kכmprεhεnsiv mεtabolik panεl (CMP)`` we wi kin du we wi de du ``annual hεlth chεkכp``, כ as pat pan di ``liva panεl`` we de chεk di liva fכnshכn.
Bɔt mɛmba dis. Yu nɔ go ebul fɔ mek di las disizhɔn bɔt siriɔs sik jɔs bay we yu luk di ALP tɛst rizɔlt. I tan lɛk di fɔs clue na di joyn fɔ fɛn di sik. Fɔ no gud gud wan wetin de apin, dɛn nid fɔ du mɔ tɛst ɛn du mɛrɛsin ɛgzam.
If yu de tek mɛrɛsin ɔltɛm we kin afɛkt di liva (e.g. paracetamol, statin dɛn we de mek yu nɔ gɛt bɔku kɔlɔstrel), yu dɔktɔ kin du ALP tɛst bak ɔltɛm fɔ chɛk if dɛn mɛrɛsin dɛn de de afɛkt yu liva.
We di ripɔt kam insay... Aw yu ɔndastand di ALP valyu dɛm?
Bɔku tɛm, dɛn kin gɛt di ripɔt insay wan ɔ tu dez. di nכmal rεnj fכ ALP kin difrεn sכmtεm frכm wan lab to כda wan. tipikli, dis valyu de bitwin 44-147 IU/L (intanashכnal yunit dεm pan wan lita). Yu ripɔt go tɔk bak bɔt wetin na dɛn nɔmal rɛnj.
If di ALP valyu de ɛlevɛt...
If yu gɛt smɔl ALP lɛvɛl pas aw i fɔ bi, nɔto sayn fɔ se yu gɛt siriɔs sik. di ALP lεvεl dεm kin εlevεt bak bikoz fכ sכ m kכmכn εn nεchכral kכz dεm .
- Pikin dεm we de gro εn yכng big pipul dεm: Bikɔs dεn bon dεm de gro kwik kwik wan, di ALP lεvεl dεm na nכmal tin.
- di bεlε: we di bεlε de, ALP kin inkrεs te to tri tεm di nכmal valyu biכs di plasεnta de prodyuz am.
- We yu de ol: Di ALP lɛvɛl kin go ɔp smɔl bak as yu de ol.
- We bon fraktכs hεl: We bon brok, ALP de inkrεs fכ sכm tεm as i de hεl.
- Fɔ it tin we gɛt bɔku fat bifo dɛn du di tɛst: Fɔ sɔm pipul dɛn, fɔ it it we gɛt bɔku fat bifo dɛn du di tɛst kin mek di ALP lɛvɛl go ɔp.
- Fɔ smok.
Bɔt sɔm mɛdikal kɔndishɔn kin mek bak di ALP lɛvɛl go ɔp bad bad wan.
| Ɔgan we dɛn afɛkt | Sik dɛm wae kin mek ALP go ɔp |
|---|---|
| Liva |
|
| Bɔn dɛn |
If di ALP valyu smɔl...
i rili rare fכ si di ALP lεvεl dεm de dכn pas fכ inkrεs. Di tin dɛn we kin mek i apin na:
- We yu nɔ gɛt minral dɛn lɛk zink ɔ magnɛsiɔm.
- di tayroyd gland de dכn dכn (Hypothyroidism).
- Hypophosphatasia (HPP) na wan sik we nɔ kin apin so ɔltɛm.
- Wilson in sik we dɛn kɔl Wilson.
- Sɔm mɛrɛsin dɛn (e.g. bɔn kɔntrol pils).
Wetin na di sayn dɛm fɔ chenj na di ALP lɛvɛl ɛn wetin fɔ du nɛks?
Bɔrku tɛm, nɔr patikyula simptom nɔr de fɔ wan ɔda ALP lɛvɛl. Bɔt di sayn dɛm kin apin dipen pan di ɔndalayn mɛdikal kɔndishɔn wae de kɔz am.
| Di simptom dɛm we gɛt fɔ du wit di liva | Di simptom dɛm we gɛt fɔ du wit bon |
| :--- :--- | :--- :--- |
| Di yay ɛn di skin we de yɔlɔ (jaundice) | Pen na di bon ɛn jɔyn |
| Dak urine ɛn layt stɔl | I izi fɔ brok bon |
| I de it am | Jɔyn swɛlin ɛn inflamɛns |
| Nɔs ɛn vɔmit | Bon difɔmiti |
| Lɔs fɔ apɛtit ɛn taya pasmak | |
| Bɛlɛ pen ɔ blo | |
Wetin fɔ du nɛks?
If yu ALP lɛvɛl nɔr nɔrmal, yu dɔktɔ go ɔda sɔm ɔda tɛst dɛm fɔ no di rayt kɔz.
1. Fɔ ripit di tɛst: Dɛn kin aks yu fɔ fast fɔ 10-12 awa ɛn afta dat yu fɔ tek di tɛst bak.
2. ALP isoenzyme test: dis kin kכrekt fכ no if di ALP we inkrεs kכmכt frכm di liva כ frכm di bon dεm.
3. GGT tεst: `Gamma-glutamyl transpeptidase (GGT)` na εnzym we de mכr spεsifi k to di liva. If GGT de εlevεt bak wit ALP, i go bi se di prכblεm de na di liva.
4. Ɔda tɛst dɛn: Apat frɔm dat, dɛn kin du imej stɔdi ɔ if nid de, dɛn kin du bayɔpsi fɔ pul wan smɔl pat pan di liva.
Fɔ pripia fɔ di tɛst ɛn di we aw i de du am
Dis na tin we rili simpul ɛn yu kin dɔn am insay sɔm minit dɛn.
- Aw fɔ pripia: Yu dɔktɔ go mɔs advays yu fɔ nɔ it ɔ drink ɛnitin pas wata fɔ 10-12 awa bifo di tɛst. I impɔtant fɔ tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn, vaytamɛn dɛn, ɛn sɔpɔtmɛnt dɛn we yu de tek. I impɔtant bak fɔ tɛl yu dɔktɔ if yu gɛt bɛlɛ.
- We:Na di lab, dɛn kin fɛn wan vein na yu an, klin di say, mek smɔl pankchɔ, ɛn jɔs tek smɔl blɔd. I kin fil lɛk smɔl prik, bɔt i nɔ kin rili pen. Dɔn dɛn put wan smɔl plasta pan di say. Na dat.
Mɛsej we dɛn kin kɛr go na os
- ALP na wan ɛnzaym we de mɔ na yu liva ɛn yu bon dɛn.
- Wan abnɔmal ALP valyu na blɔd ripɔt nɔto di las diagnosis, na jɔs wan clue na di we fɔ fɛn wan sik.
- I kɔmɔn fɔ mek di ALP lɛvɛl go ɔp pan pikin dɛn we de gro, mama dɛn we gɛt bɛlɛ, ɛn di wan dɛn we de wɛl we dɛn brok brok.
- If yu ALP lɛvɛl nɔrmal, nɔr frayd fɔ go to yu dɔktɔ. I go rifer yu fɔ ɔda tɛst fɔ no di rayt rizin.
- If yu gɛt sɔm sayn dɛm lɛk fɔ yɔlɔ na yu yay ɔ yu bon de pen, nɔr ignore dɛm. Go to dɔktɔ wantɛm wantɛm.
- Tɔk bɔt ɛni kwɛstyɔn ɔ wɔri we yu gɛt bɔt yu blɔd ripɔt opin wan wit yu dɔktɔ.
💬 Comments (0)
No kɔmɛnt nɔ de yet. Ad yu kɔmɛnt ya fɔ di fɔs tɛm.
Ad yu kɔmɛnt