Brentuximab Vedotin Vaysin: Wetin Yu Nid fɔ No

Yu dɔktɔ dɛn dɔn disayd fɔ gi yu ɔ pɔsin we yu sabi wan shot we dɛn kɔl Brentuximab Vedotin fɔ trit wan kansa kɔndishɔn lɛk limfoma? If na so, tide wi go tɔk bɔt dis mɛrɛsin, aw i de wok, di sayd ɛfɛkt dɛn we i kin gɛt, ɛn tin dɛn we yu nid fɔ no bɔt. Bikɔs dis na sɔm kayn mɛrɛsin we kɔmplikt, i impɔtant fɔ mek yu no klia wan bɔt dɛn tin ya.

Us kayn mɛrɛsin na Brentuximab Vedotin?

Fɔ tɔk am simpul wan, Brentuximab Vedotin na spɛshal vaysin we dɛn kin yuz fɔ trit wan kayn kansa we dɛn kɔl Limfoma. Dis na bikɔs wan spɛshal prɔtin de we de ɛp di kansa sɛl dɛn fɔ gro, sheb, ɛn bɔku. We dis mɛrɛsin de mek da prɔtin de nɔ wok, i de ɛp fɔ stɔp di kansa sɛl dɛn fɔ skata, ɔ at ɔl fɔ mek i slo. Fɔ tɔk klia wan, dis na mɛrɛsin we dɛn kin gi to kansa sɛl dɛn (targeted therapy). I fambul brand nem na ADCETRIS . Sɔmtɛm, yu dɔktɔ kin yuz dis mɛrɛsin bak fɔ ɔda sik dɛn. So if yu gɛt ɛni kwɛstyɔn, i go fayn fɔ aks yu dɔktɔ ɔ fama.

Wetin na de tin wae yu nid fɔ tɛl yu mɛdikal tim bifo yu tek dis mɛrɛsin?

Bifo yu bigin dis mɛrɛsin, yu nid fɔ tɛl yu kia tim sɔm tin dɛn klia wan. Bikɔs da infɔmeshɔn de go ɛp dɛn fɔ disayd if dis mɛrɛsin fayn fɔ yu ɛn aw fɔ gi am. Nɔ ayd ɛnitin, ivin di smɔl tin. If yu gɛt ɛni wan pan dɛn tin ya, mek shɔ se yu tɛl dɛn:

• Dayabitis : If yu gɛt dayabitis.
• Kidni sik : If ɛni prɔblɛm ɔ sik de na di kidni .
• Liva sik : If ɛni prɔblɛm ɔ sik de na di liva.
• Lɔw wayt blɔd sɛl: If dɛn bin dɔn no se yu gɛt smɔl wayt blɔd sɛl na yu blɔd. Dis na di sɛl dɛm we de fɛt sik na wi bɔdi.
• Lɔng sik : If yu gɛt ɛni lɔng sik, fɔ ɛgzampul , i nɔ kin izi fɔ yu fɔ blo .
• Nɛv prɔblɛm : If yu gɛt swɛt na yu an ɛn fut, yu gɛt tingling, ɔ ɔda nerve prɔblɛm (lɛk peripheral neuropathy).
• Alɛji: If yu dɔn gɛt alɛji fɔ dis mɛrɛsin, Brentuximab Vedotin, ɛni ɔda mɛrɛsin we yu dɔn yuz trade, ɛni it, ɛni day, ɔ ɛnitin we de mek yu nɔ pwɛl.
• Bɛlɛ ɔ tray fɔ gɛt bɛlɛ: If yu gɛt bɛlɛ naw ɔ yu de plan fɔ bɔn pikin insay di nɛks tɛm.
• Fɔ gi yu pikin in mama in bɛlɛ: If yu de gi yu pikin in bɛlɛ.

We dɛn tɔk dɛn tin ya kɔrɛkt wan, di mɛdikal tim kin trit yu sef wan.

Aw a go gi yu dis mɛrɛsin?

Dɛn kin gi yu dis mɛrɛsin as injɛkshɔn insay wan vein (intravenous ɔ IV infusion). Bɔku tɛm, na di mɛdikal wokman dɛn we tren na ɔspitul ɔ kansa klinik kin gi yu. Dis min se yu nɔ go ebul fɔ kɛr am go na os ɛn yuz am.

Yu tink se dɛn kin gi dis mɛrɛsin to smɔl pikin dɛn?

Yɛs, insay sɔm spɛshal kes dɛn, dɛn kin gi dis mɛrɛsin to pikin dɛn we ol 2 ia . Bɔt dɛn fɔ fala spɛshal tin dɛn fɔ tek tɛm wit. If dɛn dɔn gi yu pikin dis mɛrɛsin, tɔk to yu dɔktɔ bɔt am fayn fayn wan ɛn no di ditel dɛn.

Wetin kin apin if yu tek bɔku mɛrɛsin?

If yu tink se yu dɔn tek dis mɛrɛsin tumɔs bay mistek, kɔl pɔyzin kɔntrol sɛnta ɔ imejensi rum wantɛm wantɛm.

Impɔtant: Dɛn dɔn gi yu dis mɛrɛsin fɔ yu nɔmɔ. Nɔ sheb am wit ɛni ɔda pɔsin fɔ ɛni rizin.

Wetin a go du if a mis wan doz fɔ mɛrɛsin?

Dɛn go gi yu wan patikyula de ɛn tɛm fɔ gɛt dis vaysin. I rili impɔtant fɔ go ɛn gɛt di vaysin pan dɛn de dɛn de. If fɔ sɔm rizin yu nɔ ebul fɔ go di de we yu dɔn sɛtul, kɔl yu wɛlbɔdi tim wantɛm wantɛm ɛn mek dɛn no.

Us ɔda tin dɛn kin miks wit dis mɛrɛsin?

Sɔm mɛrɛsin dɛn de we kin mek yu gɛt prɔblɛm we yu tek am wit Brentuximab Vedotin. So, yu fɔ tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek, lɛk vaytamɛn, ɛbul mɛrɛsin, ɛn tin dɛn we yu kin it. Sɔm mɛrɛsin dɛn we yu nɔ fɔ ɛva tek wit dis mɛrɛsin na:

• Bleomycin we dɛn kɔl Bleomycin

Dɔn bak, sɔm ɔda tin dɛn de we kin miks wit dis mɛrɛsin:

• Ketokonazɔl we dɛn kɔl
• Rifampin bin de du am
• St. John's Wort - Dis na tradishonal herb we som pipul de yuz.

Dis list nɔ kɔmplit. So, tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek, ɛn if yu de smok, drink rɔm, ɔ yuz ɔda drɔgs. Sɔm tin kin afɛkt aw dis mɛrɛsin de woke.

Wetin yu fɔ tek tɛm wit we yu de tek dis mɛrɛsin?

Yu dɔktɔ dɛn go de wach yu sik gud gud wan we yu de tek dis mɛrɛsin. Dɔn bak, yu fɔ tek tɛm wit sɔm tin dɛn.

• Blɔd tɛst: Yu go nid fɔ du blɔd tɛst ɔltɛm (blɔd wok) we yu de tek dis mɛrɛsin. Dis na fɔ chɛk aw di mɛrɛsin de afɛkt yu bɔdi ɛn if ɛni sayd ɛfɛkt de.
• Risk fɔ gɛt infɛkshɔn: Yu kin gɛt smɔl risk fɔ gɛt sik, mɔ di infɛkshɔn, we yu de tek dis mɛrɛsin. So, if yu gɛt ɛni sayn fɔ kol, lɛk fiva, kol, trot we de at, ɔ ɔda tin dɛn we tan lɛk kol , nɔ fɔ mɛn yusɛf ɛn go to dɔktɔ wantɛm wantɛm. Tray fɔ avɔyd ples dɛn we pipul dɛn sik as yu ebul.
• Progressive Multifocal Leukoencephalopathy (PML): Dis kin tan lɛk se yu de mek yu fred, bɔt i impɔtant fɔ no. Na sɔm pipul dɛm, dis mɛrɛsin kin mek dɛn gɛt siriɔs infɛkshɔn na dɛn bren (Progressive Multifocal Leukoencephalopathy - PML). Dis nɔ kin apin so ɔltɛm, bɔt i kin kil pɔsin. So if yu gɛt ɛni sayn, lɛk we yu de si chenj, yu nɔ de tink, yu nɔ de tɔk, ɔ yu gɛt prɔblɛm fɔ waka ɔ tinap , tɛl yu mɛdikal tim wantɛm wantɛm. If yu nɔ ebul fɔ rich to dɛn, go to ɔda dɔktɔ wantɛm wantɛm.
• Ay blɔd shuga: Dis mɛrɛsin kin mek yu blɔd shuga go ɔp. Dis risk kin pasmak pan pipul dɛm wae dɔn ɔlrɛdi gɛt dayabitis. So, aks yu mɛdikal tim bɔt aw fɔ kɔntrol yu blɔd shuga.
• Bεlε εn we dεn de gi pikin bεlε:
• Nɔ gɛt bɛlɛ we yu de tek dis mɛrɛsin ɛn fɔ 6 mɔnt afta yu dɔn stɔp di mɛrɛsin. Dis na impɔtant tin, bikɔs dis mɛrɛsin kin rili ambɔg di pikin we de na di bɛlɛ.
• So, i impɔtant fɔ yuz di rayt kɔntrasepshɔn insay dis tɛm. Tɔk to yu dɔktɔ bɔt us we fɔ kɔntrol pikin we fayn fɔ yu ɛn yu patna.
• If yu tink se yu ɔ yu patna kin gɛt bɛlɛ, tɛl yu dɔktɔ wantɛm wantɛm.
• Nɔ gi pikin in bɛlɛ we yu de tek dis mɛrɛsin.
• Fεtiliti: Dis mεdisin kin afekt fεtiliti, we min se i nכ de fεtiliti. If yu gɛt ɛnitin fɔ wɔri bɔt dis, tɔk to yu mɛdikal tim.

Wetin na di sayd ɛfɛkt dɛm we dis mɛrɛsin kin gɛt?

Lɛk ɛni mɛrɛsin, Brentuximab Vedotin kin mek sɔm sayd ɛfɛkt. Sɔm siriɔs, sɔm nɔ so siriɔs. Di tin we impɔtant pas ɔl na fɔ tɛl yu dɔktɔ wantɛm wantɛm if yu notis ɛnitin we nɔ kɔmɔn.

Di sayd ɛfɛkt dɛn we dɛn fɔ ripɔt to di dɔktɔ wantɛm wantɛm:

If yu gɛt ɛni wan pan dɛn sik ya, kɔl yu mɛdikal tim kwik kwik wan:

• Alɛji: Skin de rɔsh, it, ayv, swel na yu fes, lip, tɔŋ, ɛn trot.
• Diziz ɛn kɔdineshɔn prɔblɛm dɛn:Diziz, nɔr de balans ɔr kɔdineshɔn, kɔnfyushɔn, ɛn i nɔr kin izi fɔ tɔk.
• Di blɔd shuga lɛvɛl (Hyperglycemia): I kin fil se yu tɔsti bad bad wan, yu nid fɔ pis bɔku tɛm, yu kin fil taya pasmak, yu nɔ kin si fayn.
• Sayn dɛm fɔ se yu gɛt di sik: fiva, kol, kɔf, trot we de at, wund we nɔ de wɛl, pen ɔ i nɔ izi fɔ pis, ɛn jenɛral diskɔmfɔt.
• Di sayn dɛm fɔ di liva injuri: I kin pen na di ɔp rayt say na di bɛlɛ, i nɔ kin want fɔ it, i kin nɔs, i kin gɛt layt kɔlɔ na di stɔl, i kin gɛt dak yɔlɔ ɔ brawn urine, i kin yɔlɔ na di skin ɛn in yay (jaundice), ɛn i kin taya we nɔ kɔmɔn.
• Di sayn dɛm wae de sho se yu gɛt smɔl smɔl rɛd blɔd sɛl dɛm: yu kin fil taya pasmak, yu kin gɛt diziz, yu ed kin at, yu nɔ kin ebul fɔ blo.
• Di sayn dɛm we de sho se pɔsin gɛt injury na in lɔng: i nɔ kin izi fɔ blo, i kin kɔf, i kin gɛt blɔd na di sputum, i kin fil pen na in chɛst, i kin gɛt fiva.
• Pen, tingling, ɔr swɛt na di an ɔr fut: Dis kin bi sayn fɔ periferik nyuropathy.
• Pankriaytis: Na bad bad bɛlɛ pen (dis kin kɔmɔt na di bak, ɛn di pen kin wɔs afta yu it ɔ we yu de muf), fiva, nɔs, ɛn vɔmit.
• Di tin dɛn we di skin kin du: Di skin kin rɛd, i kin gɛt blista, i kin kɔmɔt na di skin, ɛn ɔda tin dɛn we tan lɛk dat kin apin insay di mɔt.
• Di sayn dɛm fɔ blɔd na yu bɛlɛ: stɔl we gɛt blɔd ɔ tar, ɔ blɔd we de vɔmit we tan lɛk kɔfi grɔn.
• Bɛlɛ pen bad bad wan wantɛm wantɛm: Bɛlɛ kin at bad bad wan, dayarɛa we gɛt blɔd, fiva, nɔs, ɛn vɔmit.
• Tumor Lysis Syndrome (TLS): Dis kin apin we di kansa sεl dεm de brok dכn tu kwik. Di sayn dɛm na: nɔs, vɔmit, dayarɛa, yu nɔ de pis bɛtɛ, yu de urine dak, yu taya we yu nɔ kɔmɔn, yu kɔnfyus, yu mɔsul dɛn de twitch ɔ pen, yu at de bit fast ɔ i nɔ de bit ɔltɛm, ɛn yu jɔyn dɛn de pen.
• Brus ɔ blɔd we nɔ kɔmɔn: Brus izi, i nɔ kin izi fɔ stɔp blɔd.

Sayd ɛfɛkt dɛn we nɔ kin nid fɔ go to dɔktɔ (bɔt dɛn fɔ ripɔt to di dɔktɔ if dɛn kɔntinyu fɔ de ɔ we de mɔna yu):

Bɔku tɛm, dɛn sayd ɛfɛkt ya nɔ kin siriɔs. Bɔt if dɛn kɔntinyu ɔ de mɔna yu bɔku, tɛl yu mɛdikal tim.

• Kɔf
• Rɔnbɛlɛ
• We pɔsin taya
• Pen na di jɔyn dɛn
• Vɔmit
• Bɛlɛ de pen
• Fɔ vɔmit

Dis list nɔ de inklud ɔl di sayd ɛfɛkt dɛn we pɔsin kin gɛt. If yu notis ɛnitin we nɔ kɔmɔn, aks yu dɔktɔ bɔt am. Yu kin ripɔt bak di sayd ɛfɛkt to di FDA (Food and Drug Administration) bay we yu kɔl 1-800-FDA-1088.

Aw a fɔ kip dis mɛrɛsin?

Bikɔs dɛn kin gi yu dis mɛrɛsin na ɔspitul ɔ klinik, yu nɔ nid fɔ kɛr am go na os ɛn kip am. So yu nɔ nid fɔ wɔri bɔt am.

Fɔ dɔn, di tin dɛn we impɔtant pas ɔl fɔ mɛmba (Take-Home Message) .

Okay, so wi don tok plenti boht Brentuximab Vedotin. Fɔ dɔn, na di impɔtant tin dɛn we yu fɔ mɛmba:

• Dis na spɛshal mɛrɛsin we de kɔntrol aw di kansa sɛl dɛn de gro.
• Mek shɔ se yu tɛl yu dɔktɔ bɔt yu ɔda mɛrɛsin ɛn mɛrɛsin dɛn we yu de tek.
• Protɛkt yusɛf frɔm infɛkshɔn we yu de tek di mɛrɛsin ɛn no bɔt ɛni ɔda sayn we nɔ kɔmɔn.
• Fɔ fala di instrɔkshɔn dɛn bɔt bɛlɛ ɛn fɔ gi pikin in bɛlɛ fayn fayn wan.
• If yu gɛt ɛni kwɛstyɔn ɔ dawt, nɔ fred fɔ aks di mɛdikal tim. Dɛn de de fɔ ɛp yu.

Dis tritmɛnt kin tranga, bɔt nɔto yu wan de. Wi de wish yu trɛnk! Brentuximab Vedotin, Limfoma, Kansa Tritmɛnt, Kansa Mɛdikeshɔn, Sayd Ifɛkt, ADCETRIS