Wan stori bɔt yu at: Lɛ wi lan bɔt di ɛnzaym dɛn we de na di at ɔ di bayomak dɛn we de na di at.

Sɔntɛnde, wi kin rili fred we wi gɛt chɛst pen wantɛm wantɛm ɔ i nɔ kin izi fɔ wi fɔ blo, nɔto so? Wi kin tink se, "Dis na at atak?" Sɔntɛnde lɛk dis, spɛshal blɔd tɛst kin de we dɔktɔ dɛn kin yuz fɔ no if sɔntin nɔ rayt na yu at. Na dat dɛn kɔl dis kadyak ɛnzaym tɛst.

Wetin na dɛn ɛnzaym dɛn ya we de na di at?

Fɔ tɔk am simpul wan, di ɛnzaym dɛn we de na di at na spɛshal prɔtin dɛn we de insay di sɛl dɛn na wi at. Enzym na kemikal we de ɛp wi bɔdi fɔ du kemikal prɔses, lɛk fɔ digest , fayn fayn wan. Tink bɔt am dis we: yu at tan lɛk os. Bɔku valyu tin dɛn de insay dis os. Nɔmal wan, dɛn tin ya kin de insay di os ɛn nɔ kin kɔmɔt na do.

Bɔt if sɔntin pwɛl na dis os we dɛn kɔl at, fɔ ɛgzampul, if di at nɔ gɛt bɛtɛ ɔksijɛn (wi kin kɔl dis ischemia ), ɔ if sɔntin lɛk at atak apin, di sɛl dɛn na di at kin pwɛl. I tan lɛk we dɛn brok wan wɔl na os, di tin dɛn we de insay de jomp kɔmɔt. Dɔn, di kadyak ɛnzaym dɛn we bin de insay dɛn sɛl dɛn de kin bigin fɔ gɛda na di blɔd. So, we dɛn ɛnzaym ya de bɔku na di blɔd, na impɔtant tin we de sho se sɔm prɛshɔn, damej, ɔ strɛs dɔn de na di at . Dɛn kin kɔl dɛn tin ya bak cardiac biomarkers , bikɔs dɛn kin gi “sayn” bɔt di wɛlbɔdi na di at.

So, wetin na dis Kadyak Enzyme Marker Test?

Kadyak ɛnzaym mak tɛstWan pan dɛn na tɛst we dɛn kin tek wan sɛmpul pan yu blɔd ɛn mɛzhɔ di lɛvɛl dɛn we dɛn spɛshal ɛnzaym dɛn ya ɔ bayomak dɛn ya de. Dis na wan rili simpul blɔd tɛst. Dɛn kin pul smɔl blɔd frɔm wan vein we de na yu an.

Di dɔktɔ kin yuz dis tɛst fɔ chɛk if di lɛvɛl we dis ɛnzaym de na di blɔd nɔmal ɔ i go ɔp. If di lεvεl fכ dis εnzym hכy pas di lεvεl we dεn rεkomεnd , i min se hat atak kin dכn apin, כ sכm strεs kin de pan di at. So, dis na tɛst we rili impɔtant.

Aw dɔktɔ dɛn kin yuz dɛn kadyak bayomak ya?

Naw yu go de wɔnda, aw dɔktɔ dɛn go ebul fɔ no if pɔsin gɛt sik wit jɔs dis blɔd tɛst? Infakt, dכkta dεm kin כndastand bכku tin bay we dεn luk di lεvεl dεm fכ dεn kadyak bayomak dεm ya. I tan lɛk se ditektiv de put togɛda klyu dɛn.

Fɔ ɛgzampul:

• Acute Coronary Syndrome (ACS): Dis na wan sik wae de kam wae di blɔd de go dɔŋ wantɛm wantɛm na di at. Dis kin bi prɛkursɔr fɔ hat atak ɔr kin bi hat atak. di kadyak εnzym lεvεl kin go כp kwik kwik wan insay dis tεm.
• Myocardial Ischemia: Dis na we di at mכsul nכ de gεt inof כksijεn. Jɔs lɛk aw plant kin dray we i nɔ gɛt wata. We di at sɛl dɛn nɔ gɛt ɔksijɛn, dɛn kin strɛs ɛn pul dɛn ɛnzaym dɛn ya.
• Injury to de hat muscle: Ɔda tin dɛm, lɛk sɔm infekshɔn ɛn bad bad at atak kin mek di at mɔsul pwɛl bak. Dɛn ɛnzaym ya kin gɛda bak na di blɔd da tɛm de.

Ɛni wan pan dɛn sik ya gɛt difrɛn we fɔ trit am. So, e impɔtant fɔ gɛt kɔrɛkt diagnosis , bikɔs na da tɛm de yu kin gɛt di tritmɛnt we fit ɛn kwik.

Wetin na di gol dɛm fɔ dis kadyak bayomak tɛst?

Dɔktɔ dɛn kin chɛk di lɛvɛl dɛn we dɛn mak dɛn ya de na di at fɔ sɔm men rizin dɛn. Lɛ wi tek wan luk pan wetin dɛn bi:

• Skrin fɔ si if yu at pwɛl ɛn ɔda prɔblɛm dɛn: Sɔmtɛm wi nɔ kin gɛt ɛni big big sayn, bɔt wi kin gɛt smɔl prɔblɛm dɛn we kin bigin insay wi at. Dis tɛst kin no bak dɛn kayn prɔblɛm dɛn ya we ayd.
• Diagnose hat kondishɔn wae kin mek yu gɛt sayn dɛm lɛk chɛst pen ɛn shɔt briz : Dis na tɛst wae dɛn kin du bɔrku tɛm wae yu gɛt imejensi. If yu go na ɔspitul wit chɛst pen, dis na wan pan di fɔs tɛst dɛn we dɔktɔ dɛn go du.
• Monitor aw di at mɛrɛsin ɛn at ɔpreshɔn de wok fayn: Afta yu dɔn bigin fɔ trit yu at atak, dɛn ɛnzaym lɛvɛl ya fɔ go dɔŋ smɔl smɔl. We yu si if dat kin apin, yu kin no aw di tritmɛnt dɔn wok fayn.
• Prɛdikt wan prɔgnosis fɔ difrɛn at kɔndishɔn dɛm: Dat min se, dɛn ɛnzaym lɛvɛl ya de ɛp fɔ gɛt aydia bɔt aw di sik go go bifo, aw i siriɔs, ɛn wetin di chans fɔ mek i wɛl.

“Dis tɛst tan lɛk buk we de tɔk bɔt di at.

Usay dɛn kin du dis kadyak ɛnzaym tɛst?

Fɔ tek blɔd sɛmpul fɔ dis kadyak ɛnzaym tɛst kin bi insay jɔs sɔm minit.

• Insay imejensi: If yu gɛt imejensi, lɛk we yu de fil pen na yu chɛst, ɛn go na di ɔspitul in Imejɛnsi Tritmɛnt Yunit (ETU), dɛn go du dis blɔd tɛst rayt de.
• Insay sɔntin we nɔto imejensi: Sɔntɛnde yu dɔktɔ kin ɔda dis tɛst, we dɛn de chɛk yu ɔltɛm ɔ bikɔs ɔf ɔda sayn dɛn. If na so i bi, yu kin go na say usay dɛn de du blɔd tɛst ɛn mek dɛn du am.

Us kayn kadyak εnzym dεm (bayomak dεm) de?

Difrɛn kayn kadyak bayomak dɛn de we kin tɛl yu bɔt at prɔblɛm. Klose to ɔl dɛn tin ya na ɛnzaym ɔ prɔtin. If sɔm pan dɛn tin ya go ɔp, dat kin sho se yu gɛt sik we de ambɔg yu at ɛn yu blɔd ɔ ɔda sik na yu at.

• Troponin: Dis na di bayomak we impɔtant pas ɔl ɛn we dɛn kin yuz . Dɔktɔ dɛn kin luk fɔs pan di troponin lɛvɛl fɔ si if di at dɔn pwɛl bikɔs ɔf at atak ɔ ACS. di troponin lεvεl dεm kin bigin fכ go כp na di bכdi insay fכ awa (lεk 3-4 awa) afta di at atak, εn i kin de εlevεt fכ 12 awa. Dɔn bak, i kin kɔntinyu fɔ de ɔp na di blɔd fɔ wan ɔ tu wiks. So, sɔmtɛm, dɔktɔ dɛn kin ripit dis troponin tɛst ɛvri sɔm awa ɔ dez fɔ ɔndastand aw di tin dɔn pwɛl ɛn aw di sik de chenj.

• Natriuretic Peptides (NPs): Dis na ɔda kayn protin. Dɛn kin kɔmɔt na di blɔd we di at de strɛs tumɔs, mɔ we tin dɛn lɛk we at nɔ de wok fayn . pan ɔl we dכkta dεm kin mεzj difrεn tכp dεm fכ dεn pεpti dεm ya, di wan we kכmכn pas כl dεn kכl am N-terminal proBNP (NT-proBNP) . Dɛn kin yuz dis fɔ no aw di at de strɛs bikɔs ɔf di at we nɔ de wok fayn.

Udat nid dis kadyak enzym (biomarker) test?

Yu dɔktɔ kin ɔda dis kadyak ɛnzaym tɛst if yu gɛt sɔm sayn dɛn we de sho se yu gɛt at prɔblɛm. Dɛn kayn sayn ya na:

• Chest pen ɔ diskɔmfɔt:Dis na di men sayn wae bɔrku pipul kin frayd. I kin kam insay wan we ɔ ɔda we. Fɔ sɔm, i kin fil lɛk prɛshɔn, fɔ sɔm, i kin fil lɛk wet, fɔ ɔda pipul dɛn i kin fil lɛk bɔn. Dis pen kin pas bak to yu jaw, nek, mid-bak, sholda, ɔr lɛft an.
• Diziz: We di at nɔ de wok fayn, di blɔd we de flɔ na di bren kin go dɔŋ, ɛn dis kin mek pɔsin in ed de tɔn.
• Nɔs ɔ Vɔmit: Sɔm at atak kin sho dɛn kayn sik ya bak, mɔ pan uman dɛn.
• Bɔku swet: If yu fil kol wantɛm wantɛm ɛn yu swet bɔku bɔku wan fɔ natin, dat na sayn bak we yu fɔ pe atɛnshɔn to.
• Fɔ blo shɔt: If yu si se i nɔ izi fɔ blo ivin if yu tray smɔl, lɛk fɔ klaym stej, ɔ if yu fil se yu nɔ de blo fayn ivin we yu jɔs tinap, yu fɔ tink bɔt dis bak.
• Hat fεil exacerbation: If pכsin כlrεdi gεt hat fεil gεt di simptom dεm we de inkrεs wan wan (e.g., in leg dεm we de swel, we i de brith sכt).

If yu gɛt wan ɔ mɔ pan dɛn sik ya, i rili impɔtant fɔ go to dɔktɔ wantɛm wantɛm.

Us ɔda blɔd tɛst dɛn dɔktɔ dɛn kin yuz fɔ no if pɔsin gɛt at atak ɔ at pwɛl?

Apat frɔm di tɛst fɔ di kadyak ɛnzaym, yu dɔktɔ kin ɔda fɔ du sɔm ɔda blɔd tɛst fɔ ɔndastand yu sik mɔ:

• Complete Blood Count (CBC): Dis de sho di nɔmba fɔ di rɛd sɛl dɛn, wayt sɛl dɛn, ɛn di pletlɛt dɛn we de na di blɔd. I kin ɛp fɔ no bɔt tin dɛn lɛk we pɔsin nɔ gɛt bɛtɛ blɔd.
• Besik Mεtabolik Panεl (BMP) : Dis de tεst tin dεm lεk εlektrolayt dεm (lεk sכdiכm εn potashכm), di kidni fכ wok, εn di shuga lεvεl na di bכdi.
• Blɔd Gas Tɛst (ABG): Dis kin mɛzhɔ di ɔksijɛn, kabɔn dayɔgzayd, ɛn asid-bɛs balans na di blɔd. Dis impɔtant fɔ fɛn di tin we kin mek yu nɔ ebul fɔ blo fayn.

Us ɔda tin ɛn tɛst dɛn kin yuz fɔ no if pɔsin gɛt at atak ɔ at pwɛl?

Apat frɔm blɔd tɛst, yu dɔktɔ kin disayd fɔ du sɔm ɔda tɛst dɛn fɔ no di rayt kɔndishɔn na yu at:

• Chɛst X-ray: Dɛn kin yuz dis fɔ si tin dɛn lɛk di sayz ɛn shep fɔ di lɔng ɛn at.
• Echocardiogram: Dis tan lɛk we dɛn de du ɔltra saund skan fɔ di at. I kin luk gud wan pan di at in chεmba dεm, di valv dεm, εn aw di at de bit. Sɔntɛnde, dɛn kin du spɛshal ɛko tɛst we dɛn kɔl Transesophageal Echocardiogram (TEE) bak.
• Ilektrokardiogram (ECG ɔ EKG): Dis de rayt di ilɛktrik wok we di at de du. I kin no prɔblɛm wit di at in ritm ɛn di sayn dɛm fɔ hat atak.
• Ɛksesaiz strɛs tɛst ɔ nyuklia kadyak strɛs tɛst: Dɛn kin du dɛn tɛst ya fɔ si aw yu at kin ansa we yu de ɛksesaiz.
• Angiogram: Dɛn kin du dis tɛst fɔ si ustɛm blɔk de na di korona at we de gi blɔd to di at.
• Positron Emission Tomography (PET) Scan: Dɛn kin yuz dis ay-tek skan fɔ si aw di at sɛl dɛn gɛt wɛlbɔdi ɛn aw blɔd de flɔ fayn fayn wan.

Di kwɛstyɔn we se, “A gɛt at atak ɔ a nɔ gɛt at atak?” na big wan. Sɔntɛnde lɛk dɛn tɛm ya, yu nid klia ansa fɔ mek yu go bifo. Na dat mek dɔktɔ dɛn kin yuz kadyak bayomak tɛst ɛn ɔda tɛst. If di ɛnzaym dɛn we de na yu blɔd go ɔp, dat kin sho se yu at dɔn pwɛl, yu strɛs, ɔ yu dɔn inflam. Naw na di tɛm fɔ aks yu dɔktɔ kwɛstyɔn bɔt yu kadyak ɛnzaym ɛn wetin yu tɛst rizɔlt min.

Impɔtant tin dɛn fɔ mɛmba (Take-Home Message) .

Okay, so lɛ wi sɔma sɔm pan di tin dɛn we yu nid fɔ mɛmba frɔm wetin wi dɔn tɔk bɔt:

• di εnzym dεm na di at na di protin dεm we de kכmכt frכm di at sεl dεm. Dɛn tin ya kin gɛda na di blɔd we di at pwɛl.
• di kadyak εnzym tεst na simpul bכdi tεst we de mכsu di lεvεl dεm fכ dεn εnzym dεm ya.
• Dis tɛst kin no sɔm kayn tin lɛk at atak, ɔda at pwɛl hat, ɛn at strɛs. Troponin na di men εnzym we dεn de yuz fכ dis.
• If yu gɛt sɔm sayn dɛn lɛk we yu de fil pen na yu chɛst, i nɔ izi fɔ yu fɔ blo, ɔ yu gɛt diziz, i impɔtant fɔ go to dɔktɔ wantɛm wantɛm.
• Nɔ gɛt ɛni dawt bɔt yu tɛst rizɔlt. Tɔk to di dɔktɔ ɛn mek ɔltin klia.

Yu at na yu prɔpati we yu valyu pas ɔl. Na yu wok fɔ kia fɔ am. We yu no bɔt tɛst dɛn lɛk dɛn wan ya, dat go ɛp yu fɔ du da wok de!