Wi go tɔk bɔt limfoma we de afɛkt yu sɛntral nɛvɔ sistɛm (CNS Lymphoma)?

Sɔntɛnde, wi kin gɛt prɔblɛm dɛn na wi bɔdi wantɛm wantɛm, nɔto so? E ed we de at, i nɔ kin izi fɔ tɔk, ɔ i kin fil se i nɔ ebul fɔ kɔntrol insɛf. Sɔmtɛm wi nɔ kin pe atɛnshɔn tumɔs to dɛn tin ya, bɔt dɛn kin bi sayn bak fɔ sɔm siriɔs sik. Tide, wi go tɔk bɔt wan kayn kansa we nɔ kin bɔku bɔt we denja ɛn we kin afɛkt wi sɛntral nervɔs sistɛm.

Wetin na CNS limfoma?

Okay, so lɛ wi fɔs si wetin na dis sɛntral nɛvɔ sistɛm limfoma, ɔ `(CNS Lymphoma)` . `CNS` tinap fɔ `Sɛntral Nɛvɔs Sistɛm`. Fɔ tɔk am simpul wan, dis na wan kayn kansa we rili siriɔs we kin apin na wi sɛntral nɛvɔ sistɛm , dat na, di bren, di spɛshal kɔd (di nɛv kɔd we de insay di spɛshal kɔlɔm), di sɛribrospaynal fluid (di wata we de rawnd dis nervɔs sistɛm), ɛn di yay (bikɔs di yay dɛn kin rili nia di bren). dis de pan di kayn limfoma we dεn kכl `(Non-Hodgkin lymphoma)` .

dis `CNS` limfoma de stat na wi bכdi in wayt bכdi sεl dεm we dεn k כl limfosayt dεm . dis limfosayt dεm na pat pan wi limfatik sistεm. Yu no, dis limfatik sistɛm na wan impɔtant pat pan wi imyun sistɛm . I de ɛp wi bɔdi fɔ fɛt sik ɛn infɛkshɔn. so, if dis limfoma de divεlכp nכmכ na wi sεntri nεv sεstem εn i nכ de fכnshכn nכsay na di bכdi, wi kin kכl am `primary CNS lymphoma` . כltu, if dεn fכnshכn di limfoma bak na כda pat dεm na di bכdi, inklud di sεntri nεv sεstem, dεn kכl am `sεkכnd CNS limfoma` .

Pan ɔl we dis kansa kin kam pan ɛnibɔdi, i kin kam pan pipul dɛn we nɔ gɛt bɛtɛ wɛlbɔdi , lɛk di wan dɛn we gɛt HIV ɛn AIDS , mɔ man dɛn. Pipul wae dɔn pas 65 ia kin de pan denja bak. Bɔt, na kansa we nɔ kin apin so ɔltɛm. Ivin na kɔntri lɛk Amɛrika, na lɛk 1,500 nyu wan dɛn nɔmɔ kin gɛt di sik ɛvri ia. So, ilɛk aw yu sik, yu mɛdikal tim go ɛp yu fɔ fɛn di bɛst tritmɛnt fɔ fɛt CNS lymphoma.

Wetin na di sayn dɛm fɔ CNS lymphoma?

Naw lɛ wi si wetin na di sayn dɛm fɔ dis `CNS` limfoma. Fɔ tru, di sayn dɛn kin difrɛn difrɛn wan bay usay di tumbu de . fכ egzampl, if dis tכmכro de na di mεmbran dεm we de kכba di bren εn di spεnal kכd ( di `meninges` ), i kin nכ sho nכ simptom. Bɔt if tumbu de nia di yay, i kin chenj di we aw pɔsin de si. כ, if tכmכro de na di pat pan di bren we de kכntro di muvmεnt, i kin fil fכ sכm, chenj in bεlε lεk we yu de waka.

Dis na di kɔmɔn sayn dɛm fɔ CNS limfoma:

• Nɔs ɛn vɔmit
• Wiknɛs na yu an, yu fut, ɔ yu fes
• Wiknɛs na wan say na di bɔdi (hemiparesis) .
• I nɔ de yɛri fayn, i nɔ de yɛri
• I nɔ kin izi fɔ swɛla (dysphagia) .
• Di sayn dɛm wae de sho se di prɛshɔn de go ɔp na di bren (di ed de at bad bad wan, kɔnfyushɔn, nɔr de fil fayn) .
• Prɔblɛm dɛn we pɔsin kin si (we nɔ kin si fayn, we pɔsin kin si tu tɛm, pɔsin we de flɔt ) .
• Chenj na yu maynd (i nɔ kin izi fɔ tɔk, yu nɔ kin mɛmba, yu kin fil lɛk se yu nɔ de du natin) .
• Di sik wae kin kam pan pɔrsin wae de sik (dis kin go ɔp smɔl smɔl fɔ sɔm dez ɔr wik) .
• Nɔ ebul fɔ kɔntrol di urine ɛn stɔl (urinary ɛn fecal incontinence) .

Wetin kin mek pɔsin gɛt CNS lymphoma?

Neks, mek wi luk wetin de mek CNS lymphoma. lεk כda kayn limfoma, CNS limfoma de divεlכp we di sεl dεm na di limf no dεm bigin fכ bihayv abnכmal. Dɛn sɛl dɛn ya kin bɔku we dɛn nɔ ebul fɔ kɔntrol , ɛn dis kin mek di sɛl dɛn we gɛt wɛlbɔdi kɔmɔt. Insay CNS limfoma, di sɛl dɛn we kin bigin fɔ gro di rayt we na limfosayt, we na wan kayn wayt blɔd sɛl we dɛn kɔl B sɛl .

Risach pipul dɛn stil nɔ no bɛtɛ bɛtɛ wan wetin mek limfosayt kin bi kansa sɛl, bɔt dɛn dɔn no sɔm tin dɛn we kin mek pɔsin gɛt CNS limfoma.

Risk factors fɔ CNS limfoma

sכm kכndishכn dεm we de wik di imyun sistεm kin inkrεs di risk fכ divεlכp CNS limfoma. Dɛn tin ya we kin mek pɔsin gɛt prɔblɛm na:

• HIV/AIDS (especially if yu gɛt aktif Epstein-Barr vayrɔs infɛkshɔn) .
• Di sik we dɛn kɔl Wiskott-Aldrich (WIS) .
• Kɔmɔn vɛriɔbul imyun dɛfisiɛns stet (CVID) .
• Ataxia -telangiectasia we pɔsin kin gɛt
• Yuz imyunosuprεshכn dεm afta dεn transplant כgan

Aw dɛn kin no se pɔsin gɛt CNS lymphoma?

Yu dɔktɔ kin tɛl yu fɔ du difrɛn tɛst ɛn tin dɛn fɔ no if yu gɛt CNS lymphoma. Dɛn kin kɔl dis diagnosis bak kansa stej . Dis stej fɔ di kansa de ɛp dɔktɔ dɛn fɔ ɔndastand aw fa di kansa dɔn skata ɛn us tritmɛnt dɛn go mɔs bi.

Yu go nid fɔ du dɛn tɛst ya:

• Fɔ ɛgzam fɔ yu bɔdi : Yu dɔktɔ go chɛk yu bren, yu spayna, ɛn yu yay dɛn wɛlbɔdi. I go du nyurolɔjik ɛgzam fɔ chɛk yu sɛntral nɛvɔ sistɛm (CNS). Dɛn kin du slit lamp ɛgzam bak fɔ chɛk if wan tumbu de biɛn di yay.
• Imej tɛst : Fɔ si usay di kansa de insay di bɔdi, lɛk `(MRI)`, `(CT scan)` ɔYu dɔktɔ kin ɔda fɔ mek dɛn du PET skan. di CNS limfoma nכ kin spre pas di sεntri nεv sεstem. Bɔt i kin skata kwik kwik wan insay da sistɛm de.
• Blɔd tɛst : Blɔd tɛst kin chɛk yu sɛl dɛn fɔ si if yu gɛt sayn dɛn fɔ kansa. Dɛn tin ya na fɔ kɔnt ɔl di blɔd , fɔ stɔdi bɔt blɔd kemistri, ɛn fɔ tɛst HIV .
• Tisu ɛn wata tɛst : Dɛn kin tek sɔm pan yu spaynal wata, bon mɛro , ɔ di tumbu insɛf fɔ chɛk fɔ si if yu gɛt kansa sɛl dɛn.

Wetin na di tritmɛnt fɔ CNS lymphoma?

Infakt, no wan saiz-fit-ɔl we nɔ de fɔ trit CNS limfoma. Bifo dat, yu wɛlbɔdi tim go rikomɛnd wan tritmɛnt plan we go woke fayn fɔ yu bay tin dɛm lɛk yu ej, if yu gɛt HIV/AIDS, ɛn if dɛn jɔs dɔn no di kansa ɔ i dɔn kam bak afta tritmɛnt (we de kam bak) . Bɔku tɛm, dɛn go yuz kɔmbayn tritmɛnt dɛn.

Di tritmɛnt dɛm fɔ CNS limfoma na:

• Kimotɛrapi : Dis kin min fɔ yuz drɔgs fɔ kil di kansa sɛl dɛn. Bɔku tɛm dɛn kin yuz ay dos fɔ di kemotɛrapi drɔg mɛtɔtreksɛt (HD-MTX) fɔ trit nyu CNS limfoma we dɛn dɔn no.
• Radiation therapy : Dis de yuz enaji bim fɔ kil di kansa sɛl dɛm. Wan kayn redyushɔn tɛrapi we kin ɛp fɔ pul di sik dɛn na di wan ol bren raytin . I de kil di kansa sɛl dɛn ɔlsay na di bren.
• Targeted therapy : Dis de yuz tin dεm lεk protin dεm εn antibodi dεm fכ atak di kεnsar sεl dεm. Rituximab ɛn ibrutinib na tritmɛnt dɛn we yu dɔktɔ kin tɛl yu fɔ du.
• Stem sel transplant : Insay stem sel transplant, dɛn kin gi yu wɛlbɔdi blɔd sɛl fɔ tek ples fɔ di blɔd sɛl dɛn we dɔn pwɛl bikɔs ɔf kansa tritmɛnt lɛk kemotɛrapi ɛn redyushɔn tɛrapi.
• Klinik trial : Yu dɔktɔ kin tɛl yu fɔ tek pat pan klinik trial we de tɛst nyu tritmɛnt dɛn. Di trayal dɛm we dɛn de du naw de stɔdi aw nyu targeted therapy drugs ɛn nyu kɔmbaynshɔn fɔ kemotherapy drugs de wok fayn fɔ trit CNS lymphoma.

If yu gɛt HIV ɔ yu gɛt AIDS, yu fɔ kɔntinyu fɔ tek yu antiretroviral therapy (ART) we dɛn de trit yu fɔ CNS lymphoma.

Wetin na de kɔmplikeshɔn ɛn sayd ɛfɛkt dɛm wae de kam wit tritmɛnt?

Tritmɛnt fɔ CNS limfoma kin mek i gɛt sayd ɛfɛkt . Yu dɔktɔ go ɛksplen dɛn tin ya to yu bifo tɛm. Fɔ ɛgzampul, di raytin we de na di wan ol bren kin kil di kansa sɛl dɛn na di bren. Bɔt i kin mek yu gɛt siriɔs sayd ɛfɛkt bak we kin afɛkt aw yu bren de wok. Ɔl di tritmɛnt opshɔn dɛn gɛt risk.

Tɔk to yu dɔktɔ bɔt di bɛnifit ɛn prɔblɛm dɛn we yu gɛt fɔ du wit yu tritmɛnt plan. Aks if dɛn kin rɛkɔmɛnd palliative care, we kin ɛp yu fɔ manej di sayd ɛfɛkt dɛm ɛn di ɔl impak we kansa gɛt pan yu layf.

Wetin a go ɛkspɛkt wit dis sityueshɔn?

CNS lymphoma na kansa we de gro fast fast , ɛn i gɛt bɔku chans fɔ kam bak afta dɛn dɔn trit am. Bɔt di chans we yu gɛt fɔ wɛl, ɔ di prɔgnosis , kin dipen pan sɔm patikyula tin dɛn. Dɛn tin ya na:

• yu ej
• Yu ɔvalayn wɛlbɔdi stetmɛnt
• Yu HIV stetmɛnt
• Usay di tumbu de
• Di rizulyt fɔ yu blɔd kemistri tɛst (dɛn kin sho aw di kansa dɔn afɛkt yu insay ɔgan dɛm) .

Yu mɛdikal tim go wok wit yu fɔ fɛn di tritmɛnt plan we go gi yu di bɛst chans fɔ liv ɛn nɔ go ridyus yu kwaliti fɔ liv.

Wetin na di rεkכvεshכn rεt fכ CNS limfoma?

Risach pipul dɛn kin ripɔt di nɔmba fɔ pipul dɛn we gɛt kansa bay we dɛn de luk ɔmɔs pipul dɛn we gɛt wan patikyula kansa stil de alayv afta wan patikyula tɛm, bɔku tɛm na fayv ia. di fayv ia rεt fכ pipul dεm we gεt CNS limfoma na bכt 30% . Dat min se tri pan ɛvri tɛn pipul dɛn we gɛt CNS lymphoma kin liv afta fayv ia.

Bɔt dɛn statystik ya rili jɛnɛral . Dɛn nɔ kin tek ɔda patikyula tin dɛn we kin afɛkt di chans we pɔsin gɛt fɔ liv. Fɔ ɛgzampul, if yu imyun sistɛm nɔ wik, ɔ if di limfoma nɔ bin dɔn pas di bren, bɔku tɛm di tin we kin apin kin bɛtɛ. Dɔn bak, dɛn rεt ya fɔ liv nɔr de sho aw nyu tritmɛnt de afɛkt yu layf εkspεktεns.

Yu dɔktɔ na di bɛst pɔsin fɔ ɛksplen wetin go apin to yu tumara bambay bay aw yu gɛt wɛlbɔdi ɛn aw yu gɛt patikyula kansa.

Aw a kin kia fɔ misɛf?

Fɔ liv wit lymphoma kin rili at . Yu kin fil fɔ wɔri bɔt us tɛst ɛn tritmɛnt dɛn we yu go gɛt fɔ du. Sɔntɛm yu nɔ go no aw fɔ tɛl ɔda pipul dɛn aw yu de fil.

Na di tɛm lɛk dis, .Yu fɔ tray fɔ gɛt ɔl di sɔpɔt we yu ebul fɔ gɛt . Dat kin min se yu fɔ tɔk to di wan dɛn we yu lɛk, ilɛksɛf i nɔ izi. Ɔ, i kin min fɔ aks yu dɔktɔ bɔt palliativ kia ɔ sɔpɔt grup dɛn . Ɔlman in kansa joyn difrɛn. Bɔt i impɔtant fɔ kɔnɛkt wit ɔda pipul dɛn na ɛvri step na di joyn.

Ustɛm a fɔ go to di dɔktɔ?

Ivin if yu CNS lymphoma de insay remission (dat min se yu nɔ gɛt ɛni sayn ɔ simptom fɔ di kansa igen), yu go stil nid fɔ de chɛk-ap ɔltɛm fɔ chɛk if i kam bak. Yu go nid fɔ go to yu dɔktɔ bɔku tɛm insay di fɔs fayv ia afta yu dɔn gɛt tritmɛnt. Dis na bikɔs bɔku pan di kes dɛm fɔ CNS limfoma we kin kam bak kin apin insay di fɔs fayv ia.

Us kwɛstyɔn dɛn a fɔ aks di dɔktɔ?

Na sɔm kwɛstyɔn dɛn we yu kin aks yu dɔktɔ:

• Us tɛst dɛn a go nid fɔ gɛt fɔ no wetin a dɔn plan fɔ trit?
• Wetin na di prɔblɛm ɛn bɛnifit dɛn we difrɛn tritmɛnt dɛn kin gɛt?
• Aw ɔltɛm a go gɛt fɔ kam insay fɔ tɛst fɔ si aw di kansa de ansa to tritmɛnt?
• A fit fɔ tek pat pan klinik trial ? Yu kin se yu fɔ du dat?
• Yu go rekomend palliative care fo mi?

Di mɛsej we impɔtant pas ɔl fɔ kɛr go na os

CNS limfoma na siriɔs sik we yu nid fɔ wach gud gud wan ɛn gɛt tritmɛnt plan we dɛn mek fɔ yu. I impɔtant fɔ wok klos wit wan mɛdikal tim we gɛt ɛkspiriɛns fɔ trit limfoma ɔ kansa we de afɛkt di sɛntral nɛvɔ sistɛm (CNS).

Yu mɛdikal tim kin ɛksplen yu tritmɛnt opshɔn dɛm, ɛp yu fɔ wej dɛn bɛnifit ɛn di risk ɔr sayd ɛfɛkt dɛm wae kin kam, ɛn kɔnɛkt yu wit palliativ kia spɛshal pipul dɛm wae kin gi yu kɔmfɔt as yu de disayd fɔ yu nɛks step.

` CNS limfoma, sεntri nεv sεstem, kεnsar, bren kεnsar, limfoma, imyun sistεm, tritmεnt