Yu mɛmba di filin we yu kin gɛt we dɔg de rɔnata yu wantɛm wantɛm na strit, ɔ we yu gɛt yu ɛgzam kwɛstyɔn pepa na yu an? Yu at de rɔsh, yu at de bit fast, yu bɔdi de kol ɛn swet... Dis na wetin wi kɔl di " fight-or-flight " rispɔns. Dat min se di we aw di bɔdi de rɛdi insɛf fɔ "fayt ɔ rɔn." Wi ɔl dɔn yɛri bɔt adrenaline, we de wok na wi bɔdi dis tɛm. Bɔt yu dɔn yɛri bɔt in brɔda, we de wok di sem we lɛk adrenaline, bɔt i difrɛn smɔl? Dɛn kɔl am norepinephrine. Wi go tok abaut dis tu tide.
Wetin na dɛn katekolamin ya?
Fɔ tɔk am simpul wan, Norepinephrine ɛn Epinephrine na tu mɛmba dɛn na wan grup ɔf ɔmon dɛn we dɛn kɔl ‘Catecholamines’ . tu smɔl smɔl gland dɛn we de ɔp di kidni dɛn de mek dɛn ɔmon ya na wi bɔdi. Wi kin kɔl dɛn tin ya ‘Adrenal Glands’. sכmtεm dεn tin ya na di bren de mek dεm bak as ‘Neurotransmitters’ , kεmikכl mεsenja dεm we de kכri mεsej dεm na di nεv sεstem.
Di ɔda men mɛmba na dis grup na dopamin . We yu fil se yu de fred, trɛtin, ɔ strɛs, dɛn tri ɔmon ya kin wok togɛda fɔ rɛdi yu bɔdi. We dɛn tin ya de na ay levul na yu bɔdi, .
- Di blɔd we de flɔ na di bren ɛn di mɔsul dɛn kin bɔku.
- Di atɛnshɔn ɛn de wach mɔ ɛn mɔ.
- Di at rit de go ɔp.
- Blɔd prɛshɔn kin go ɔp.
Sɔntɛnde, if yu gɛt sɔm sayn dɛn we nɔ de dɔn lɛk ay blɔd prɛshɔn we yu nɔ de kɔntrol bay tritmɛnt, yu de wɔri ɔltɛm, yu de nɔs, ɛn yu ed de at bad bad wan, yu dɔktɔ kin tɛl yu fɔ du blɔd ɛn urine tɛst fɔ chɛk yu lɛvɛl fɔ dɛn katekolamin ya. If dɛn kɔntinyu fɔ gɛt dɛn tin ya, dat kin bi sayn fɔ wan kayn kansa we nɔ kin bɔku we kin kam na di adrenal gland dɛn.
Norepinephrine ɛn Epinephrine - Tu Job fɔ Tu
Pan ɔl we dɛn tu tin ya de wok togɛda, di men wok dɛn we dɛn de du difrɛn smɔl. Lɛ wi si aw dat kin wok.
| Norepinephrin (Nɔradrenalin) we dɛn kɔl . | Epinefrin (Adrenaline) we dɛn kɔl Epinefrin (Adrenaline) . |
|---|---|
| Bɔku tɛm na nyurotransmittaI de wok lɛk mɛsenja na di nervɔs sistɛm. | Bɔku tɛm i kin wok lɛk ɔmon . If ɛnitin apin, i kin kɔmɔt na di adrenal gland insay di blɔd. |
| I de wok ɔltɛm na di bɔdi, ɛn i de kɔntrol tin dɛn lɛk slip, atɛnshɔn, ɛn blɔd prɛshɔn. | Menli impliment onli in taims of imejensi . |
| Di men wok na fɔ mek di blɔd prɛshɔn kɔntinyu bay we i de mek di blɔd vesel dɛn kɔnstrikt. | Di men wok na fɔ mek di at bit kwik kwik wan, fɔ mek yu gɛt mɔ ɛnaji, ɛn fɔ mek yu nɔ no se yu de fil pen. |
Wetin kin apin wit norepinephrine?
Norepinephrine tan lɛk wan kɔntrol we de ɔltɛm na wi bɔdi. I nɔ de wok nɔmɔ pan imejensi, bɔt i de wok bak pan ɛvride layf.
- Atɛnshɔn ɛn slip: Norepinephrine de ɛp yu fɔ wek na mɔnin ɛn ɛp yu fɔ de wach ɛn pe atɛnshɔn ɔl di de. Ivin we yu tinap wantɛm wantɛm, sɔm norepinephrine kin kɔmɔt fɔ ɛp yu fɔ kɔntinyu fɔ du sɔntin.
- Blɔd prɛshɔn: I kin mek di blɔd vesel dɛn kɔnstrikt fɔ mek blɔd prɛshɔn nɔ go dɔŋ tumɔs. Bɔt if dis lɛvɛl de ɔp ɔltɛm, i kin mek pɔsin gɛt ay blɔd prɛshɔn.
- Imɔshɔn: If yu nɔr de fil fayn, dat kin mek yu gɛt pwɛl hat ɛn ɔda tin dɛm wae gɛt fɔ du wit yu maynd wɛl bɔdi. Dɔn bak, if yu gɛt bɔku bɔku norepinephrine wantɛm wantɛm, i kin mek yu fil fayn ɛn yu kin fred .
Wetin kin apin wit Epinephrine (Adrenaline)?
Epinephrine na di adrenaline we wi ɔl no. Na di wan we de kam sev lɛk hiro we i gɛt imejensi.
- Strɔng ɛn spid: I de mek yu at rit ɛn blɔd prɛshɔn go ɔp, ɛn i de ad shuga (glukɔs) to di blɔd, we de gi yu ɛnaji wantɛm wantɛm.
- Ridyushɔn fɔ pen : Ivin if yu wund, i kin mek yu nɔ fil pen fɔ sɔm tɛm, ɛn ɛp yu fɔ kɔntinyu fɔ fɛt ɔ rɔn.
- Fɔ mek yu gɛt mɔ trɛnk: Ɛpinefrin kin mek yu gɛt mɔ trɛnk fɔ sɔm tɛm bak.
Bɔt if di lɛvul fɔ epinephrine na pɔsin we de strɛs ɔltɛm, i kin mek i nɔ rɛst, i nɔ kin slip, ɛn i kin ivin pwɛl in at.
Aw dɛn kin yuz dɛn tin ya as mɛrɛsin?
Bikɔs dɛn tu pawaful tin ya kin apin wantɛm wantɛm, dɔktɔ dɛn kin yuz dɛn bak as mɛrɛsin.
| Ustɛm fɔ gi Norepinephrine | Ustɛm fɔ gi epinephrine |
|---|---|
| fכ inkrεs blכd prεshכn we i dכn to wan lεvεl we de mek yu layf de pan denja (e.g., sεptik shכk, kadyak arest). | Fɔ gi layf bak (CPR) we di at stɔp. |
| we di prεshכn dכn dכn biכs fכ di spεnal anεsthεsia. | As imejensi tritmɛnt fɔ siriɔs alɛji (anaphylaxis) . |
| Sɔm ADHD ɛn antidipreshan mɛrɛsin dɛn kin wok bay we dɛn kin mek di Norepinephrine na di bren bɔku. | Fɔ opin di say dɛn we pɔsin kin blo we i gɛt asma . |
| insay kes dεm fכ nyurojεnik shכk we kכz fכ injuri na di spεnal kכd. | Fɔ mek di pupil big we dɛn de du ɔpreshɔn pan di yay. |
Epinephrine ɛn siriɔs alɛji riakshɔn (Anaphylaxis) .
Wan pan di impɔtant tin dɛn we dɛn kin yuz fɔ yuz ɛpinefrin na as imejensi tritmɛnt fɔ siriɔs alɛji (anaphylaxis), we kin mek pɔsin in layf de pan denja. Sɔm pipul kin gɛt dis sik afta dɛn dɔn gɛt sɔm it ɔ insɛkt sting (e.g., wasp sting).
Sɔm pan de sayn dɛm wae de sho se yu gɛt anafilaksis na:
- Trot de swel ɔ tayt
- I nɔ kin izi fɔ yu fɔ blo
- Chɛst tayt ɔ kɔf
- Diziz ɔr nɔr kin no natin
Dɛn kin advays pipul dɛn we gɛt siriɔs alɛji lɛk dis fɔ kɛr wan epinephrine ɔto-injɛkta we dɔktɔ gi dɛn ɔltɛm (lɛk EpiPen) wit dɛn. If yu injekt am kwik kwik wan, i kin sev yu layf if yu gɛt alɛji.
I rili impɔtant: If, pan ɔl we yu de yuz di epinephrine injɛkshɔn, yu sik nɔ sɔlv ɔl ɔ if di sik kam bak, i impɔtant fɔ go na ɔspitul in Imejɛnsi Dipatmɛnt (ETU) wantɛm wantɛm.
Wetin kin apin if dɛn ɔmon ya dɔn go dɔŋ na di bɔdi?
Sɔntɛnde, di ɔmon dɛn we wi bɔdi de mek kin stɔp. If dɛn ɔmon ya nɔ bɔku, dat kin mek pɔsin gɛt difrɛn wɛlbɔdi prɔblɛm dɛn.
- Prɔblɛm dɛm we gɛt fɔ du wit di lɔw norepinephrine lɛvɛl: Wɔri, pwɛl hat, ADHD, ed pen, mɛmori lɔs, slip prɔblɛm, low blɔd prɛshɔn (haypotension).
- Prɔblɛm dɛn we gɛt fɔ du wit di lɔw epinephrine lɛvɛl: wɔri, pwɛl hat, ed we de at, slip prɔblɛm, lɔw blɔd shuga lɛvɛl (haypoglycemia).
If yu gɛt sɔm kayn sik lɛk dis, i go fayn fɔ mek yu tɔk to yu dɔktɔ fɔ no if di tin we de mek yu gɛt dis sik na we di ɔmon dɛn de chenj.
Mɛsej we dɛn kin kɛr go na os
- Norepinephrine ɛn epinephrine na tu "fight-or-flight" ɔmon dɛm we de ɛp yu we yu fil se yu de fred ɔr de trɛtin yu.
- Norepinephrine (Noradrenaline) tan lɛk di bɔdi in tɛmostayt. I de wok ɔltɛm, de kɔntrol tin dɛm lɛk atɛnshɔn ɛn blɔd prɛshɔn.
- Epinephrine (Adrenaline) tan lɛk faya alarm. I kin jɔs go ɔf insay imejensi ɛn gi yu wan instant boost.
- As mɛrɛsin, dɛn kin yuz Norepinephrine mɔ fɔ mek blɔd prɛshɔn go ɔp bad bad wan, ɛn dɛn kin yuz Epinephrine as tritmɛnt kwik kwik wan fɔ siriɔs alɛji riakshɔn (anaphylaxis).
- If yu nɔ balans na dɛn ɔmon dɛn ya, dat kin afɛkt yu bɔdi ɛn maynd, so go to dɔktɔ if yu gɛt ɛnitin fɔ wɔri bɔt.
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