Yu de fil taya ɔltɛm bikɔs yu gɛt lɔw blɔd prɛshɔn? Mek wi tok abaut Erythropoietin!

Sɔntɛnde, yu kin fil taya ɛn yu nɔ gɛt layf? Wan rizin fɔ dis na we di rɛd blɔd sɛl dɛn we de na di bɔdi de go dɔŋ. Wi bɔdi gɛt wan rili impɔtant ɔmon we de ɛp fɔ mek dɛn rɛd blɔd sɛl ya. Dat na di ɔmon we wi go tɔk bɔt tide. I nem na Erythropoietin, ɔ EPO fɔ shɔt tɛm.

Wetin na Ɛritropoɛtin?

Fɔ tɔk am simpul wan, Erythropoietin na ɔmon we wi kidni dɛn kin mek mɔ. Yes, yu yɛri am rayt, we wi tink bɔt kidni, wi jɔs de tink bɔt urine prodakshɔn, bɔt di kidni dɛn de du bɔku mɔ na wi bɔdi. Wan pan dɛn impɔtant wok dɛn de na fɔ mek dis ɔmon (EPO). Dis ɔmon (EPO) de ɛp fɔ mek wi gɛt wɛlbɔdi nɔmba fɔ di rɛd blɔd sɛl dɛn, dat na di ɛrythrocytes, na wi bɔdi.

Sɔntɛnde, dɔktɔ dɛn kin yuz wan we we dɛn mek wit ɛrythropoietin fɔ trit anemia , mɔ pan tin dɛn lɛk sik we nɔ de mɛn na di kidni . Dɔn bak, sɔm atlet dɛn kin yuz dis drɔg di rɔŋ we fɔ mek dɛn ebul fɔ du mɔ. Bikɔs EPO de mek di ɔksijɛn we de rich na dɛn mɔsul dɛn bɔku. Yu tink se dat nɔ de akɔdin to lɔ? Ok?

כda nem dεm fכ dis εrythropoietin na εrythropoietin, εmatopoietin, εn εmopoietin. Bɔt, dɛn ɔl min di sem tin.

Us savis erythropoietin (EPO) de gi wi bɔdi?

Okay, naw mek wi si wetin exactly EPO de du. Di men wok we EPO de du na fɔ ɛp fɔ mek rɛd blɔd sɛl dɛn. Na dɛn rɛd blɔd sɛl ya de kɛr ɔksijɛn go na di tisu dɛn na wi bɔdi. Di ɔksijɛn kin chenj to ɛnaji, dɔn di kabon dayɔgzayd kin kɔmɔt na wi tisu dɛn. We yu blo, dɛn sem rɛd blɔd sɛl ya kin ɛp fɔ pul da kabon dayɔgzayd de.

dis na wetin kin apin: we wan spεshal kayn sεl na wi kidni dεn no se di כksijεn lεvεl na wi bכdi dכn sכm, dεn kin mek dεn prodyuz (EPO) bכku. Dɔn dis ɔmon (EPO) kin tɛl di pat we tan lɛk spɔnj na wi bon dɛn, we na di bon mɛro, fɔ mek mɔ rɛd blɔd sɛl dɛn. Tink bɔt am lɛk we yu de gi ɔda tin to faktri.

we di sεl dεm na di kidni dεm no se כksijεn de insay di bכdi, dεn de ridyus di εrythropoietin we de mek. Dis na tin we rili kɔmpleks, bɔt dɛn kin kɔntrol am fayn fayn wan.

Bɔt sɔm mɛrɛsin dɛn kin afɛkt di kayn EPO we di kidni dɛn kin mek. Dɛn kin prodyuz tumɔs ɔ nɔ kin prodyuz inof. Dis kin mek prɔblɛm wit ɔl tu bɔku ɔ tu smɔl rɛd blɔd sɛl dɛn.

Wetin kin apin if di erythropoietin (EPO) lɛvɛl go ɔp?

If di EPO lɛvɛl go ɔp we nɔ fayn, dat min se if di bɔdi gɛt mɔ EPO pas aw i nid, di nɔmba fɔ di rɛd blɔd sɛl dɛn kin go ɔp bak we nɔ nid. Wi kin kɔl dis polycythemia. I tan lɛk se trafik jam na rod, we rɛd blɔd sɛl bɔku, blɔd kin stɔp.

Wetin na di rizin dɛn fɔ dis kayn inkris na di EPO lɛvɛl?

Bɔku rizin kin de we mek di EPO lɛvɛl kin ay pasmak.

• Fɔ lɔng tɛm we yu gɛt ɔksijɛn we nɔ bɔku: Dis kin apin to pipul dɛn we de smok ɔ we de na say dɛn we gɛt mawnten, we ay pas di si. Dis na bikɔs di briz nɔ gɛt bɛtɛ ɔksijɛn as yu de go ɔp. Bɔt i nɔmal fɔ mek pɔsin we de na say we gɛt mawnten gɛt ay levul pan EPO, we na we fɔ mek di bɔdi adap.
• Anemia nɔr kin kam bikɔs ɔf kidni sik: Sɔntɛnde, anemia nɔr kin kam bikɔs ɔf wan kidni prɔblɛm. Bɔt we di kidni dɛn no se di bɔdi nɔ gɛt bɛtɛ rɛd blɔd sɛl dɛn, dɛn kin mek mɔ EPO fɔ ɛp fɔ mek rɛd blɔd sɛl dɛn. Dis na nɔmal, nid inkris bak pan EPO.
• Kansa we nɔ kin bɔku: Na smɔl tɛm nɔmɔ, sɔm kayn kansa kin mek di kidni dɛn mek tumɔs EPO we nɔ fayn.

Wetin na di tin dɛm wae kin mek yu gɛt low erythropoietin (EPO) lɛvɛl?

di men εn mכst kכmכn kכz fכ lכw EPO lεvεl na krכnik kidni sik ( CKD ). We di kidni dɛn dɔn pwɛl, dɛn nɔ kin ebul fɔ mek inof EPO. Dis kin mek di EPO lɛvɛl smɔl. Dis kכndyushכn, wit di lכw EPO lεvεl, kin mek i gεt anemia. Yu kin si ɔmɔs prɔblɛm kin apin if di kidni dɛn nɔ de wok fayn, nɔto so?

Dɔn bak, wan sik we dɛn kɔl Polycythemia Vera kin mek di EPO lɛvɛl smɔl. Dis na wan kayn blɔd kansa. Insay dis, wan chenj we de apin na di jɛnɛtiks kin mek wi bon mɛro mek tumɔs rɛd blɔd sɛl dɛn. Dɔn, di kidni dɛn kin no se tumɔs rɛd blɔd sɛl dɛn de na di bɔdi, ɛn dɛn kin ridyus di EPO we dɛn kin mek.

Aw dɛn kin trit di low erythropoietin (EPO) lɛvɛl?

If yu EPO lɛvɛl smɔl, di fɔs tin fɔ du we yu de trit am na fɔ fɛn di ɔndalayn kɔz ɛn trit am.

di men we fכ trit anemia we de kכz fכ lכw EPO lεvεl dεm dairekt wan na fכ injεkt rεkombinεnt εrythropoietin. dεn kכl dεn tin ya bak εrythropoietin-stimulating agents כ ESAs. dis na כl tu di nεchכral EPO כmon εn wan sεntetik, כ lab-meid, fכm fכ EPO. Dɔktɔ dɛn kin klon ɔ kɔpi di EPO jin ɛn gi yu as shot fɔ mek dɛn mek mɔ rɛd blɔd sɛl dɛn.

Dɛn (ESA) vaysin ya na dɛn kin yuz mɔ fɔ mɛn sik dɛn we nɔ de mɛn na di kidni.Trit anemia we kin kam bikɔs yu kidni nɔ de wok fayn. Dɛn kin gi dɛn bak to pipul dɛn we gɛt sɔm kayn kansa we nɔ kin bɔku.

Bɔt dɛn (ESA) vaysin ya kin mek sɔm sayd ɛfɛkt dɛn. Nɔto ɔlman kin gɛt dɛn, bɔt sɔm pipul dɛn kin:

• Di ay blɔd prɛshɔn
• Fiva
• Diziz we pɔsin kin gɛt
• Vɔmit
• Pen na di say we dɛn injɛkshɔn

Bifo yu bigin dis kayn tritmɛnt, i rili impɔtant fɔ tɔk bɔt ɔl dis wit yu dɔktɔ ɛn aks ɛni kwɛstyɔn we yu gɛt.

Aw dɔktɔ dɛn kin mɛzhɔ di lɛvɛl we di erythropoietin (EPO) de?

Yu dɔktɔ kin mɛzhɔ yu EPO lɛvɛl wit blɔd tɛst. Dis blɔd tɛst kin ɛp fɔ no if chenj dɛn we de apin na yu blɔd sɛl dɛn, lɛk polycythemia, anemia, ɔ ɔda bon mɛro kɔndishɔn dɛn de afɛkt EPO prodakshɔn.

Na dis na wetin yu kin du we yu de tek blɔd:

1. Fɔs, klin di skin we de rawnd di vein na yu an wit sɔntin lɛk ayodin ɔ isopropyl alkol.

2. Dɔn, yuz wan tin nidul (bɔku tɛm na 21 gej, we smɔl smɔl pas wan rɛgyula iaring post), dɛn kin pul smɔl blɔd frɔm wan vein na yu an.

3. Dɔn dɛn kin sɛn di blɔd sɛmpul to lab fɔ mek dɛn analays am.

We di lab dɔn fɔ tɛst yu blɔd sɛmpul, yu dɔktɔ go kɔl yu fɔ tɔk bɔt di tɛst rizɔlt ɛn ansa ɛni kwɛstyɔn we yu gɛt. Sɔntɛnde, ivin if yu EPO lɛvɛl de insay di nɔmal rɛnj, yu kin nid ɔda tritmɛnt. Na yu dɔktɔ go disayd dis.

Wetin fɔ bi di nɔmal lɛvɛl fɔ di εrythropoietin (EPO)?

Dɔktɔ dɛn kin mɛzhɔ EPO insay miliyunit pan wan mililita (mU/mL). di EPO lεvεl fכ hεlty pכsin kin kכmכt frכm 4 to 26 mU/mL.

Bɔt mɛmba se yu (EPO) tɛst rizɔlt kin difrɛn smɔl dipen pan bɔku tin dɛn. Fɔ ɛgzampul:

• yu ej
• Yu biyolojikal sɛks
• Yu ɔvalayn wɛlbɔdi stetmɛnt

So, na yu dɔktɔ go analayz yu rizɔlt kɔrɛkt wan ɛn tɛl yu if yu (EPO) lɛvɛl wɛl ɔ nɔ wɛl. Nɔ jɔs luk di nɔmba dɛn ɛn jomp to kɔnklushɔn, okay?

Wetin na di we dɛm fɔ inkrisayz di εrythropoietin (EPO) lɛvɛl na di nכmal wan?

If yu gɛt kronik kidni sik (CKD), ɔ if yu gɛt anemia wit lɔw EPO lɛvɛl, sɔm chenj dɛn na yu it ɛn yu layf kin ɛp fɔ mek yu EPO lɛvɛl go ɔp smɔl. Bɔt, dɛn fɔ jɔs du dɛn tin ya wit dɔktɔ advays.

• Ɛksesaiz: Risach dɔn sho se we yu de ɛksesaiz ɔltɛm, we yu de du ɛksɛsayz we yu de du mɔ (we yu de du ɛksɛsayz wit trɛnk), yu bɔdi de yuz mɔ ɔksijɛn. Dɔn yu bren kin tɛl yu bɔdi fɔ mek mɔ EPO. Sɔm ɛgzampul dɛn bɔt dis kayn ɛksesaiz na fɔ rayd baysikul, fɔ jok, ɛn fɔ swim.
• Ayɛn we de insay di it: Ayɔn na wan men tin we de insay di ɛmoglobin. Dis ɛmoglobin de ɛp fɔ kɛr ɔksijɛn go na di sɛl dɛn na wi bɔdi. it dεm we gεt ayron inklud rεd mit, eg yכlk, liva, tofu, εn it dεm we gεt fכt wit ayכn (e.g., sכm siriכs, bred, εn pasta).

Bɔt dɛn tin ya nɔmɔ nɔ go mek big difrɛns, mɔ if di sik we de ɔnda dis sik rili bad. So i impɔtant fɔ fala yu dɔktɔ in advays.

Tin dɛn we yu fɔ mɛmba frɔm ɔl dis (Take-Home Message) .

Erythropoietin na wan rili impɔtant, impɔtant ɔmon we de tɛl wi bon mɛro fɔ “mek mɔ rɛd blɔd sɛl dɛn.” Bɔt sɔntɛnde, wi bɔdi nɔ kin mek tumɔs rɛd blɔd sɛl dɛn, ɔ i nɔ kin mek bɔku. Dɛn tu tin ya kin mek pɔsin gɛt wɛlbɔdi prɔblɛm.

If yu de fil taya ɛn taya ɔltɛm, nɔ ignore am. Yu kin go to dɔktɔ ɛn mek dɛn chɛk yu blɔd (EPO). Dɔn di dɔktɔ kin tɛl yu di tritmɛnt we fit yu pas ɔl. Mɛmba se di balans we dɛn ɔmon ya gɛt rili impɔtant fɔ mek pɔsin gɛt wɛlbɔdi.