Wetin na Felty Syndrome? Dis impɔtant fɔ una we gɛt at at sik!

Yu kin gɛt pen bak na yu jɔyn dɛn, yu kin swel, ɛn yu an ɛn fut dɛn kin stif smɔl na mɔnin, nɔto so? Bɔrku tɛm, dɛn tin ya kin bi bikɔs ɔf rεumatoid at. Bɔt yu no se ɔda prɔblɛm de we kin kam wit dis at at sik, bɔt dɛn nɔ no am so, bɔt i rili impɔtant fɔ no bɔt? Dat na di sik we dɛn kɔl Felty Syndrome. Lɛ wi tɔk bɔt dis smɔl mɔ tide.

Wetin rili na Fɛlti Sindrom?

Fɔ tɔk am simpul wan, Fɛlti Sindrom na tri tin dɛn we kin apin togɛda. Dɛn na:

• Rimatɔyd Atraytis - Na jɔyn inflamɛns we bɔku pan una sabi.
• Nyutropenia - Dis na we di nyutrofil dεm we de dכn, we na wan kayn wayt bכdi sεl na di bכdi.
• Splenomegaly - dis min se di splin, we na wan כgan na di bכdi, de big pas aw i nכmal.

Bɔrku tɛm e kin bigin wit rεumatoid arthritis (RA). Di ɔda tu kɔndishɔn dɛn kin apin as kɔmplikeshɔn fɔ RA. Dɔktɔ dɛn kin kɔl dɛn tin ya ‘ɛkstra-atikul manifestɔshɔn’. Dat min se, at at nɔto jɔs di jɔyn dɛn nɔmɔ, bɔt i kin afɛkt di jɔyn dɛn we de na do. Dis na bikɔs ɔf di inflammatory prɔses we de mek di at at sik. Pan ɔl we i kɔmɔn fɔ mek dɛn kayn ifɛkt ya apin ausayd di jɔyn dɛn we gɛt RA, Fɛlti Sindrom na sɔm kayn tin we nɔ kin apin so ɔltɛm.

Aw dis kin afɛkt yu?

Di sik we dɛn kɔl Felty’s syndrome kin bigin wit Rimatɔyd Atraytis. Dɔn yu kin gɛt bad bad pen ɛn yu jɔyn dɛn kin swel. Dɔn, we tin dɛn lɛk Nyutropenia ɛn Splenomegaly apin, i kin afɛkt yu imyun sistɛm . Nyutropenia na we wan kayn wayt blɔd sɛl we dɛn kɔl nyutrofil we de go dɔŋ. Dɛn nyutrofil ya na wan kayn sɛl we rili impɔtant we de protɛkt wi bɔdi frɔm sik dɛn. So we dɛn de go dɔŋ, di chans fɔ gɛt sik dɛn kin bɔku. di splin we big kin bi כda rizin bak fכ dis dכn we di nyutrofil dεm de dכn.

Aw dis sik kin kɔmɔn?

Felty’s syndrome kin apin pan lɛk 2% pan pipul dɛm wae gɛt rεumatoid arthritis. Lɛk RA, di sik we dɛn kɔl Felty’s syndrome kin bɔku pan uman dɛn lɛk tri tɛm pas man dɛn. i intrestin fכ no se, kכlכsכl כl di pipul dεm we gεt RA we de divεlכp Fεlty in sεndrכm na ‘seropositive’. Dis min se we dɛn de tɛst dɛn fɔ no se dɛn gɛt sɔntin we dɛn kɔl rεumatoid factor antibodies na dɛn blɔd. ‘seronegative’ pipul dεm, we min se pipul dεm we nכ gεt dεn antibodi dεm, nכ kin gεt Fεlty in sεndrכm.

Wetin na di sayn dɛm fɔ dis?

Bɔrku tɛm, di fɔs sayn dɛm wae kin apun na di wan dɛm wae gɛt rεumatoid at. Dɛn tin ya na:

• Pen na di jɔyn dɛn
• Di jɔyn dɛn we de swel
• Joint stiffness, mɔ na mɔnin

Sɔm pipul kin gɛt ɔda sayn dɛm apat frɔm RA na dɛn jɔyn. Fɔ ɛgzampul:

• di lכmp dεm we de fכm כnda di skin nia di joyn dεm (dεn kכl dεn rεumatoid nodul dεm) .
• di limf no dεm we swεla na ples dεm lεk di nεk εn di armpit dεm
• Di liva kin swel ɛn i kin fil pen we yu tɔch am.
• Dray yay ɛn mɔt (dɛn kɔl dis Sjogren’s syndrome) .
• Rɛd, swɛlin yay (dɛn kɔl dis episkleritis) .
• Skin lɛsin, mɔ na di leg dɛn
• Sayn dɛn we de sho se blɔd de kɔmɔt ɔnda di skin
• I nɔ izi fɔ blo bikɔs di lɔng dɛn de swel
• Chɛst pen bikɔs ɔf di swel we de rawnd di at
• Fiva
• Taya ɛn taya
• Nɔbɔdi nɔ kin want fɔ it ɔ we yu nɔ kin ɛksplen to yu wet

Apat frɔm dɛn tin ya, Felty Syndrome gɛt ɔda sayn dɛn bak. Sɔntɛnde, dɛn sayn ya kin apia bifo di RA simptom bigin.

• Infekshɔn dɛn we kin kam bɔku tɛm, we kin de fɔ lɔng tɛm. Sɔm ɛgzampul dɛn na kol, bɛlɛ at, ɛn infɛkshɔn na di skin.
• Spleen we de swel. Yu kin fil am na di an ɛn i kin mek yu fil pen.
• Skin di kɔlɔ we de chenj (lɛk spat).

Bɔt di wɔndaful tin na dat, sɔmtɛm dɛn kin no se yu gɛt Fɛlti Sindrom we nɔr gɛt ɛni sayn. Blɔd tɛst ɛn skan kin sho se yu gɛt ɔl di tri sik bifo yu ivin fil ɛni sayn.

Us ej dis kin bigin?

Felty Syndrome kin kam pan ol pipul dɛm, bitwin 50 ɛn 70. Fɔ bɔrku pipul dɛm, Felty Syndrome kin kam afta dɛn dɔn gɛt sɔm kayn rεumatoid arthritis fɔ lɛk 10 to 15 ia.

Wetin mek Felty Syndrome kin apin?

Rimatɔyd at na ‘ɔtoimyun sik’. Dis min se wi yon imyun sistɛm de atak sɔm pat dɛn na wi yon bɔdi lɛk se na ɛnimi. Bɔku sayɛnsman dɛn biliv se Felty Syndrome na siriɔs prɔblɛm we kin kam wit RA. insay dεn כtoimyun sik dεm ya, wi bכdi de prodyuz ‘antibodi dεm’ εgεst sכm protin dεm. dis antibodi dεm de go εn grap dεn protin dεm de εn signal dεm fכ dεstroy. Dis na aw inflamɛns kin bɔku.

Dɛn antibodi ya nɔ kin de ɔltɛm na RA. Bɔt pan pipul dɛm wae gɛt Felty Syndrome, dɛn antibodi dɛm ya kin rili de. di prεsεns fכ dεn antibodi dεm ya na rizin we mek RA de bi mכr siriכs εn כda ifekt dεm we de ausayd di jכint dεm (εkstra-articular manifestations) de inkrεs. RA wit antibodi dεm dεn kכl am ‘seropositiv RA’. Risach sho se ɔl tu di sɛropositiv RA ɛn Felty Syndrome gɛt fɔ du wit sɔm ‘jɛnɛtik factor dɛm’. Dis min se dɛn kin pas dɛn to jɛnɛreshɔn dɛn te to sɔm mak.

Aw rεumatoid atraytis (RA) kin mek yu gɛt nyutropenia ɛn splenomegaly?

Aw Nyutropenia De Apin

Nyutropenia na we di wayt bכdi sεl dεm we dεn kכl nyutrofil dεm de dכn. Tu men rizin dɛn de fɔ dis. Wan na dat yu bon mכro nכ de prodyuz inof nyutrofil dεm. Ɔ, di nyutrofil dɛn we de na yu bɔdi de pwɛl. Na Felty Syndrome, dɛn tu tin ya kin apin. di כtoimyun prכsεs we wi bin dכn tכk bכt kin ambɔg di nyutrofil dεm we de na di bon mכro, εn di nyutrofil dεm we dεn dכn כlrεdi prodyuz kin pwεl. כlso, we di splin big na כda rizin fכ di nyutrofil dεm we de dכn.

Aw Splenomegaly kin apin

Yu splin in wok na fɔ filta ol blɔd sɛl dɛn we nɔ gɛt yus frɔm yu blɔd. Bɔt we yu splin tu big (splenomegaly), i kin wok pasmak ɛn bigin fɔ pul bɔku gud blɔd sɛl dɛn. Sɔntɛnde, rεumatoid atraytis kin mek yu splin big. Di rayt rizin nɔ klia yet. di splin kin big bak we yu nכ gεt nyutropenia. Dɔn bak, na smɔl tɛm nɔmɔ, Fɛlti Sindrɔm kin apin we yu nɔ gɛt splin we dɔn big.

Wetin na di denja kɔmplikeshɔn dɛm wae kin kam wit Felty Syndrome?

Bikɔs Felty Syndrome kin mek yu imyun sistɛm wik, yu kin gɛt siriɔs infɛkshɔn ɔltɛm . Ivin if yu kin gɛt smɔl sik we yu kin trit izi wan, dis sik kin tranga so dat i kin kɔntinyu fɔ de ɛn sɔntɛnde i kin mek yu layf de pan denja. Baktri infεkshכn we dεn nכ kכntrol kin mek yu gεt wan denja kכndyushכn we dεn kכl sepsis. Pipul wae gɛt Felty Syndrome kin gɛt bɔrku risk bak fɔ gɛt sɔm kayn kansa, lɛk lymphoma.

Bɔt nɔ fred we yu yɛri dɛn tin ya. Dɛn risk ya de, bɔt dɛn kin kɔntrol dɛn if dɛn trit dɛn fayn ɛn pe atɛnshɔn to dɛn.

Aw fɔ no dis?

Dɔktɔ dɛn kin no se i gɛt Fɛlti Sindrom we dɛn si se rεumatoid at, nyutropenia, ɛn splenomegaly ɔl de. (I nɔ kin izi fɔ mek dɛn no di sik we dɛn nɔ gɛt di splin we dɔn big.)

Di tɛst dɛn we dɛn kin du na:

• Blɔd tɛst: Na kɔmplit blɔd kɔnt, spɛshal fɔ chɛk di nɔmba fɔ di nyutrofil dɛn.
• X-ray fɔ di jɔyn dɛn: Chɛk fɔ si if yu gɛt at at.
• Spleen skan: Fɔ ɛgzampul, dɛn kin du ɔltra saund ɔ CT skan.
• Bɔn mɛrɔ bayɔpsi: .Dis kin ɛp fɔ mek shɔ se no ɔda mɛrɛsin nɔ de.

Wetin na di tritmɛnt fɔ dis?

Tri men gol de wae yu de trit Felty Syndrome:

• Kɔntrol di ɔndalayn kɔndishɔn fɔ Rimatɔyd Atraytis.
• If nyutropenia bad, trit am dairekt.
• Fɔ mek yu nɔ gɛt di sik ɛn fɔ trit am if i apin.

Felty Syndrome kin bi bikɔs ɔf di rεumatoid arthritis (RA) we dɛn nɔ trit ɔ we dɛn nɔ kin kɔntrol fayn. Fɔ bɔku pipul dɛn, nyutropenia kin bɛtɛ bak as dɛn RA de bɛtɛ. So, dɔktɔ dɛn kin luk fɔs fɔ pik fayn fayn sik-modifying antirheumatic drugs (DMARD) fɔ RA. Dɛn kin tray bak fɔ avɔyd di mɛrɛsin dɛn we de mek dɛn nɔ gɛt bɛtɛ wɛlbɔdi as dɛn ebul.

Bɔrku kayn DMARD de wae dɛn kin yuse fɔ Felty Syndrome:

• Methotrexate ɛn folic acid (dɛn de ridyus di sayd ɛfɛkt dɛm we methotrexate gɛt) .
• Abatacept we de na di wɔl
• Rituximab we dɛn kɔl Rituximab
• Leflunomide we dɛn kɔl

Bɔt if yu nyutropenia nɔ impɔtant wit dɛn DMARD ya, ɔ if yu nyutropenia rili bad, ɔ if yu dɔn ɔlrɛdi gɛt infɛkshɔn, yu dɔktɔ go tray ɔda tritmɛnt fɔ mek yu nyutrofil bɔku. Dɛn tin ya kin bi:

• wan vaksin we dεn kכl G-CSF (granulocyte colony-stimulating factor).
• Shɔt tɛm kɔtikosterɔyd mɛrɛsin dɛn.
• ‘Splenectomy’ - Dis min se yu fɔ ɔspitul fɔ pul di splin we pasmak.

Dɔn bak, dɔktɔ dɛn go du spɛshal tin dɛn fɔ protɛkt yu frɔm infɛkshɔn, mɔ if di tritmɛnt we yu de gi yu afɛkt yu imyun sistɛm. Dɛn kin rikɔmɛnd tin dɛn lɛk:

• Fɔ tek bɔku bɔku antibayɔtiks.
• Fɔ gɛt di vaysin dɛn we nid fɔ de.
• Pe spɛshal atɛnshɔn to di wɛlbɔdi na yu mɔt ɛn yu tit.

If pɔsin we gɛt Felty Syndrome gɛt infekshɔn, dɔktɔ dɛn kin tek am siriɔs wan. If dis apin to yu , yu nid fɔ gɛt tritmɛnt wantɛm wantɛm . Yu dɔktɔ go gi yu strɔng mɛrɛsin.

Wetin na di layf we pɔsin kin liv wit Felty Syndrome?

Nɔr statystik nɔr de naw bɔt aw pipul dɛm wae gɛt Felty Syndrome kin liv. Bɔt, in jɔnal, di tritmɛnt opshɔn dɛn dɔn impɔtant bad bad wan insay di las ia dɛn. So chans de fɔ mek ɛni tritmɛnt go fayn fɔ yu. Di men risk fɔ day pan Fɛlti Sindrom stil na frɔm siriɔs infɛkshɔn . So, fɔ tek step fɔ protɛkt yusɛf frɔm infekshɔn kin mek big difrɛns to yu wɛlbɔdi fɔ lɔng tɛm.

Felty Syndrome na wan kɔmplikeshɔn wae nɔr kin bɔrku ɛn bɔrku tɛm wae dɛn nɔr kin no bɔt wae gɛt rεumatoid arthritis (RA). If yu gɛt RA we yu nɔ ebul fɔ kɔntrol fɔ lɔng tɛm, ɔ if yu mɛrɛsin dɛn stɔp fɔ wok lɛk aw dɛn bin de wok trade, yu kin gɛt Felty Syndrome. Sɔm pipul dɛn kin gɛt am ɛn nɔr kin gɛt ɛni sayn. I kin mek yu at pwɛl smɔl fɔ no se sik we de ambɔg yu jɔyn dɛn kin afɛkt yu blɔd sɛl dɛn bak.

Wae yu dɔn ɔlrɛdi de dil wit RA, ɛn sɔmtɛm ɔda sayn dɛm, e kin tranga fɔ gɛt nyu diagnosis. Bɔt Felty Syndrome nɔr kin kɔz bɔrku nyu sik, ɛn e nɔr kin nid ɛni ɔda tritmɛnt. Di impɔtant tin na fɔ no bɔt di prɔblɛm dɛn we kin apin. If yu wok wit yu dɔktɔ fɔ trit yu RA ɛn fɔ mek yu nɔ gɛt infɛkshɔn, yu kin ebul fɔ kɔntrol di Felty Syndrome.

Fɔ dɔn, tin dɛn we wi fɔ mɛmba

Felty Syndrome na wan sik wae kin apun pan sɔm pipul dɛm wae gɛt rεumatoid arthritis (RA). i kin bi se di wayt bכdi sεl dεm we dεn kכl nyutrofil dεm na yu bכdi de dכn (nyutropenia) εn di splin de big (splenomegaly).

• Di men tin we kin mek yu gɛt infɛkshɔn ɔltɛm, so i rili impɔtant fɔ protɛkt yusɛf frɔm infɛkshɔn.
• Pan ɔl we dis kin tan lɛk se i de mek pɔsin fred smɔl, dɛn kin kɔntrol dis sik fayn fayn wan if dɛn gi dɛn di rayt mɛrɛsin ɛn advays .
• If yu gɛt RA, de wach fɔ dɛn ɔda sayn ya. If yu gɛt ɛnitin we de mɔna yu , mek shɔ se yu tɔk to yu dɔktɔ. Dɛn go ebul fɔ ɛp yu.

` Felty Syndrome, Rumatoid Atraytis, Nyutropenia, Splenomegaly, Atraytis, Jɔyn Inflameshɔn, Nyutrofil, Splin, Imyuniti