Yu blɔd vesel dɛnsɛf kin pwɛl? Lɛ wi tɔk bɔt Fibrinoid Necrosis!

Di smɔl smɔl blɔd vesel dɛn we de ɔlsay na wi bɔdi tan lɛk paip dɛn we de kɛr wata. Na dɛn wan ya kin kɛr blɔd go na ɔl di pat dɛn na wi bɔdi. So, wetin kin apin if sɔntin pwɛl dɛn blɔd vesel ya? Tide wi go tɔk bɔt wan sik we kin siriɔs, ɛn dat na wan sik we dɛn kɔl Fibrinoid Necrosis . Nɔ fred, lɛ wi ɔndastand dis simpul wan.

Wetin na fibrinoid nɛkrɔsis?

Fɔ tɔk am simpul wan, fibrinoid nɛkrɔsis na fɔ pwɛl di insay wɔl dɛn na di smɔl smɔl blɔd vesel dɛn na wi bɔdi, mɔ di smɔl smɔl at dɛn . Tink bɔt am lɛk se wata paip de bɔs. We di blɔd vesel dɛn pwɛl dis kayn we, dɛn kin brok, wund , blɔd, ɛn ivin brus insay di bɔdi.

Di wɔd “nɛkrɔsis” min se di sɛl dɛn day . I min se di sɛl dɛn de day bikɔs ɔf aksidɛnt, injuri, ɔ blɔd we nɔ de wok igen. fibrinoid nεkrכsis na di sem kayn tin, we min se di sεl dεm na di wכl dεm na di bכdi vεsul dεm de day.

Aw dis tin kin apin?

Dis kin tan lɛk se i kɔmplikt smɔl, bɔt tink bɔt am dis we. Wi gɛt wan imyun sistɛm na wi bɔdi. I tan lɛk difens fɔs na wi bɔdi. Na dis sistɛm de protɛkt wi frɔm sik . Bɔt sɔntɛnde dis imyun sistɛm kin wok pasmak ɔ kɔnfyus.

insay fibrinoid nεkrכsis, di imyun sistεm de bi ova aktv εn i de rilis sכm tin dεm. Dɛn tin ya kin stɔp na di insay wɔl dɛn na wi blɔd vesel dɛn. Dɔn, inflammation , we min se i de swel ɛn rɛd. Dis inflamɛns kin mek di sɛl dɛn we de na di wɔl dɛn na di blɔd vesel dɛn day. In ɔda wɔd dɛn, i tan lɛk se wi yon difens dɛn de atak wi yon sɛl dɛn.

Wetin kin mek pɔsin gɛt fibrinoid nɛkrɔsis?

Ɛni kɔndishɔn we kin pwɛl di blɔd vesel kin mek dis apin. Bɔku men tin dɛn de we kin mek pɔsin gɛt dis sik:

• Blɔd prɛshɔn we rili ay : Dɛn kɔl dis (Malignant Hypertension) ɔ (Hypertensive Crisis) . Nɔmal wan, di blɔd prɛshɔn fɔ pɔsin we gɛt wɛlbɔdi fɔ smɔl pas 130/80 mmHg. Bɔt pan dis kɔndishɔn we dɛn kɔl (Malignant Hypertension), di blɔd prɛshɔn kin go ɔp to 180/120 mmHg ɔ ivin pas dat. We dis kin apin, wiFibrinoid necrosis kin apin bay we i de pwɛl di blɔd vesel dɛm we de kɛr blɔd to impɔtant ɔgan dɛm lɛk di at , bren, ɛn kidni dɛm. Dis na rili siriɔs imejensi ɛn i nid fɔ go to dɔktɔ wantɛm wantɛm.

• Autoimmune diseases : As wi bin dɔn tɔk, dɛn sik ya na sik dɛn we wi yon imyun sistɛm kin atak wi yon bɔdi. Fɔ ɛgzampul:
• (Rɔmatɔyd Atraytis ) .
• (Lupus) (Lupus sik – i kin afɛkt bɔku ɔgan dɛn lɛk skin, jɔyn, kidni)
• (Rheumatic Fiver – na wan sik we kin apin afta yu gɛt trot infɛkshɔn ɛn i kin afɛkt di at)

• Preeclampsia: Dis na wan sik we sɔm mama dɛn kin gɛt we dɛn gɛt bɛlɛ. I kin gɛt ay blɔd prɛshɔn ɛn ɔda sayn dɛm.

• (Subacute Bacterial Endocarditis): Dis na baktri infεkshכn na di insay layn na di at.

• Vasculitis: Fɔ tɔk am simpul wan, na inflamɛns na di blɔd vesel dɛm, we min se i de swel. Sɔm ɛgzampul dɛn bɔt dis na:
• (Polyarteritis Nodosa) we gɛt di sik.
• (IgA Vasculitis) (dɛn bin de kɔl am Henoch-Schönlein purpura)

Naw yu go dɔn ɔndastand se dis sik nɔr kin kam bikɔs ɔf jɔs wan rizin, bɔt i kin gɛt fɔ du wit difrɛn sik dɛm.

Wetin na di sayn dɛm fɔ dis sik?

Bikɔs fibrinoid nɛkrɔsis kin pwɛl di blɔd vesel dɛn, di men sayn na we i de blɔd . Dis kin apin difrɛn we dɛn:

• Di blɔd we de kɔmɔt na di gɔm.
• Blɔd na di stɔl (blak ɔ dak rɛd).
• Blɔd na di urine – wi kɔl dis (Hematuria) .
• Brus na difrɛn say dɛn na di bɔdi (lɛk se i brus we dɛn nɔ hit ɛnisay).
• Blɔd we de kɔmɔt insay di bɔdi (dɛn nɔ kin si dis frɔm ɔdasay, bɔt dɛn kin ɔndastand am frɔm ɔda sayn dɛm).
• Nɔs blɔd de kɔmɔt.

If yu gɛt blɔd lɛk dis, nɔ ignore am . I rili impɔtant fɔ go to dɔktɔ fɔ advays.

Wetin na di prɔblɛm dɛn we kin kam wit Fibrinoid Nɛkrɔsis?

De kɔmplikeshɔn wae kin kam wit dis sik kin dip pan de ɔndalayn sik wae mek i kam. Fɔ ɛgzampul, tink bɔt:

• Di wan we wi bin tɔk bɔt (Malignant Hypertension) , dat na if fibrinoid nɛkrɔsis apin na di blɔd vesel dɛn na di kidni bikɔs ɔf di ay blɔd prɛshɔn, i kin mek di kidni nɔ wok fayn .
• If dis kɔndishɔn apin bikɔs ɔf sik lɛk lupus , skin lɛsin ɛn at sik kin apin.

Dat min se di komplikashכn dεm nכ de ditarεmin nכto כnli bay di fibrinoid nεkrכsis, bכt bak bay di כndalayn sik.

Aw dɛn kin no dis sik? (Diagnosis) .

We di sɛl dɛn day, dɛn kin pul wan tin we dɛn kɔl fibrin . Dis tin we dɛn kɔl fibrin na di men pruf fɔ no dis sik.

Pathologists , we spɛshal fɔ no bɔt sik dɛn, kin tek wan sampul pan di tisu we dɔn pwɛl ɛn luk am ɔnda maykroskɔp. Dɔn dɛn kin si if dis tin (Fibrin) dɔn de.

We yu tek wan tisu sɛmpul dɛn kɔl am bayɔpsi . di we aw dεn de du dis bayopsi de difrεn dipכnt pan di say we di sik de:

• Skin biopsies: Dɛn kin skrap wan tint layt pan di skin kɔmɔt na di skin, ɔ dɛn kin tek smɔl pat wit spɛshal tul (panch tul). Sɔntɛnde dɛn kin kɔt smɔl say fɔ tek sampul frɔm dip ples.
• Internal biopsies: Fɔ tek tisu sɛmpul frɔm wan ɔgan insay di bɔdi, dɔktɔ dɛn kin yuz nidul ɔ wan tin we dɛn kɔl ɛndoskɔp . Ɛndoskɔp na tin we tan lɛk tin we gɛt kamɛra ɛn smɔl smɔl tin dɛn na wan ɛnd. dis kin pas insay di bכdi fכ tek wan tisu sεmpl.

Aw fɔ trit am? (Tritmɛnt)

Fɔ tɔk tru, no patikyula, standad tritmɛnt nɔ de fɔ fibrinoid nɛkrɔsis. Bɔt dɔktɔ dɛn kin kɔntrol di blɔd we de kɔmɔt . I dipen pan di say ɛn di kayn we aw di blɔd de kɔmɔt.

Apat frɔm dat, di tin we impɔtant pas ɔl na fɔ trit di sik we de ɔnda di sik we mek pɔsin gɛt fibrinoid nɛkrɔsis .

Fɔ ɛgzampul, if na ay blɔd prɛshɔn de mek i gɛt am, dɛn kin gi am mɛrɛsin fɔ kɔntrol am. If na prɔblɛm wit di imyun sistɛm, mɛrɛsin dɛn de fɔ kɔntrol am ɛn stɔp fɔ pwɛl di blɔd vesel dɛn mɔ.

So, di men tin we dɛn kin pe atɛnshɔn pan fɔ tritmɛnt na fɔ trit di rizin we mek dɛn gɛt di sik .

Aw fɔ protɛkt yusɛf frɔm fibrinoid nɛkrɔsis? (Prɛvenshɔn) .

Bifo yu tray fɔ protɛkt yusɛf ɔlsay frɔm dis, di bɛst tin we yu go du na fɔ ridyus di risk fɔ gɛt di ɔndalayn kɔndishɔn dɛn we de mek yu gɛt dis.

• Si yu dɔktɔ ɔltɛm fɔ mek dɛn chɛk yu. Da we de, if wɛlbɔdi prɔblɛm de, dɛn kin no am ɛn trit am bifo i siriɔs.
• If yu dɔn gɛt wan sik we kin mek yu gɛt dis (e.g. ay blɔd prɛshɔn, dayabitis, ɔtoimyun sik), fala yu dɔktɔ in instrɔkshɔn dɛn ɛksaktɔli . Tek yu mɛrɛsin dɛn di rayt tɛm ɛn kɔntinyu fɔ liv yu layf lɛk aw dɛn tɛl yu fɔ du am.

Wetin na di tumara bambay fɔ pɔrsin wae gɛt dis sik? (Prɔgnosis) .

dis rili dipכnt pan di siriכs כndalayn kכndyushכn we mek di fibrinoid nεkrכsis. Sɔm tin kin apin to yu layf, i kin mek yu nɔ gɛt bɛtɛ layf, ɛn i kin ivin mek yu day bifo tɛm.

Fɔ ɛgzampul, if dɛn nɔ trit di sik we wi bin dɔn tɔk bɔt (Malignant Hypertension) kwik kwik wan, dɛn kin ridyus di pɔsin in layf fɔ lɛk tu ia so. Na dat mek i impɔtant fɔ go to dɔktɔ jɔs lɛk aw di sik dɔn sho.

Ustɛm yu fɔ go to dɔktɔ?

If yu ɛva kam fɔ no se yu blɔd vesel dɛn dɔn pwɛl, ɔ if yu gɛt ɛni wan pan di sayn dɛn we wi bin dɔn tɔk bɔt (especially blɔd we yu nɔ ɛksplen), i impɔtant fɔ go to dɔktɔ fɔ mek dɛn fala yu fayn fayn wan.

If yu fala di tritmɛnt plan we yu dɔktɔ gi yu, yu go ebul fɔ kɔntrol yu sik ɛn mek yu nɔ pwɛl mɔ.

Fibrinoid necrosis na wan sik we de pwɛl di blɔd vesel dɛm. Di tin dɛn we kin mek i apin kin siriɔs, so i nid fɔ mek dɔktɔ wach am gud gud wan. If yu de go to yu dɔktɔ ɔltɛm, yu kin ebul fɔ kɔntrol yu wɛlbɔdi fayn fayn wan ɛn mek yu nɔ gɛt prɔblɛm dɛn we kin kɔmɔt frɔm di tin dɛn we kin apin to yu.

Mɛsej we dɛn kin kɛr go na os

• Fibrinoid necrosis na damej pan smɔl smɔl blɔd vesel dɛm.
• Di men tin wae kin mek dis kin kam na di sik dɛm lɛk ay blɔd prɛshɔn ɛn ɔtoimyun sik dɛm.
• Di men sayn na difrɛn kayn blɔd we de kɔmɔt.
• Dɛn kin nid fɔ tek bayɔpsi fɔ no if pɔsin gɛt di sik.
• Di tritmɛnt de mɔ pan di ɔndalayn kɔz.
• I rili impɔtant fɔ go to dɔktɔ if yu gɛt sɔm kayn sik ɔr tin wae kin mek yu gɛt dis sik, bikɔs i kin siriɔs if yu nɔr pe atɛnshɔn to yu.

A op se dis infɔmeshɔn go yusful to yu. Stay wit wɛlbɔdi!