Tin dɛn we yu nid fɔ no bɔt Livmarli (Maralixibat) .

Sɔm pikin dɛn, mɔ di wan dɛn we gɛt wan sik we nɔ kin apin so ɔltɛm we dɛn kɔl Alagille syndrome, kin gɛt it we dɛn nɔ ebul fɔ bia wit dɛn skin. Nɔr wɔd nɔr de fɔ tɔk bɔt de diskɔmfɔt wae dɛn kin gɛt. So, wan spɛshal mɛrɛsin we dɔktɔ dɛn kin gi pan dɛn kayn tin ya na Maralixibat, we dɛn kin sɛl bɔku tɛm ɔnda di brand nem Livmarli. If dɛn dɔn gi yu ɔ yu pikin dis mɛrɛsin, yu kin gɛt bɔku tin fɔ wɔri ɛn aks kwɛstyɔn bɔt am. Lɛ wi tɔk bɔt ɔl dis simpul ɛn fayn tide.

Fɔ tɔk am simpul wan, wetin kin apin wit dis Maralixibat drɔg?

Okay, di medikal nem fo dis wan kin soun likli komplikayt. Maralixibat na wan drɔg we de insay wan klas ɔf drɔgs we dɛn kɔl ileal bile acid transporter (IBAT) inhibitors. Naw, nɔ kɔnfyus, a go ɛksplen am simpul wan.

Imajin, di bayl we di liva de mek na wi bɔdi gɛt sɔntin we dɛn kɔl bayl asid. Insay Alagilille syndrome, dɛn bayl asid ya nɔ kin kɔmɔt fayn fayn wan na di bɔdi ɛn insted dɛn kin gɛda na di blɔd. we di lεvεl fכ di bayl asid dεm na di bכdi go כp, i de it bad bad wan na di skin.

So wetin dis Maralixibat mεdisin de du na fכ kכntrכl di absכpshכn fכ dεn bayl asid dεm bak insay di bכdi frכm di intestines. Fɔ tɔk di kɔrɛkt tin, i de blok da prɔses de. Dɔn di bayl asid we de na di blɔd kin go dɔŋ, ɛn smɔl smɔl dɛn kin kɔntrol da it we de mek pɔsin vɛks na di skin bak. Yu ɔndastand?

Tin dɛm wae yu fɔ tɛl yu dɔktɔ bifo yu bigin fɔ tek mɛrɛsin

I rili impɔtant fɔ mek yu dɔktɔ no bɔt yu kɔmplit wɛlbɔdi stetmɛnt bifo yu gi yu dis mɛrɛsin. So, if yu gɛt ɛni wan pan dɛn tin ya, mek shɔ se yu tɛl yu dɔktɔ.

• If dɛn bin dɔn no se yu gɛt smɔl vaytamɛn A, D, E, ɔ K na yu blɔd.
• If yu gɛt bɛlɛ, ɔ yu de op fɔ gɛt bɛlɛ insay di nɛks tɛm.
• If yu na mama we de gi pikin in bɛlɛ.

Bay dis infɔmeshɔn, di dɔktɔ go disayd di tritmɛnt plan we go fayn fɔ yu.

Aw ɛksaktɔli a kin yuz dis mɛrɛsin?

Dis na sɔlv we dɛn kin tek bay mɔt. Fɔ mek yu go gɛt di bɛst pan di mɛrɛsin, i impɔtant fɔ yuz am di rayt we.

• Tɛm: Dɛn fɔ tek dis di sem tɛm ɛvride, 30 minit bifo di fɔs it fɔ di de.
• Mekɔp: Yuz di spɛshal ɔral sirinj, spun, ɔ drɔp nɔmɔ we de kam wit dis mɛrɛsin fɔ mɛzhɔ am. Nɔ yuz ti spɔnj ɔ sup spɔnj ɔltɛm na os fɔ ɛni rizin, bikɔs dɛn nɔ go mɛzhɔ di rayt doz.
• Wit ɔda mɛrɛsin: If yu de tek ɔda mɛrɛsin (bile acid binding resins) lɛk cholestyramine ɔ colesevelam, i fɔ de bitwin 4 awa bitwin fɔ tek dɛn ɛn dis Maralixibat mɛrɛsin.Yu nid fɔ kip am. Dat min se yu nid fɔ tek di ɔda mɛrɛsin ɔ 4 awa afta yu tek Maralixibat ɔ 4 awa bifo. Tɔk to yu dɔktɔ bɔt dis ɛn mek am klia mɔ.
• Instrɔkshɔn fɔ Yuz: Rid di INSTRUKSHƆN FƆ YUZ we de kam wit di mɛrɛsin fayn fayn wan. If ɛnitin de we yu nɔ ɔndastand, aks yu dɔktɔ.

Wetin a go du if a mis wan doz fɔ tek mɛrɛsin?

Wit di bizi na layf, e pɔsibul fɔ fɔgɛt fɔ tek wan doz fɔ mɛrɛsin. If dat apin, tek am jɔs lɛk aw yu mɛmba. Bɔt if i let pas 12 awa frɔm di tɛm we yu kin tek am, skip di doz we yu nɔ tek. Tek di nɛks doz na di tɛm we dɛn dɔn sɛtul. Nɔ ɛva tek tu doz wan tɛm fɔ mek di doz we yu mis.

Wetin yu kin du if yu tek bɔku mɛrɛsin?

If yu tink se yu dɔn tek bɔku mɛrɛsin, nɔ panik ɛn go wantɛm wantɛm na di ɔspitul we de nia yu Imejɛnsi Tritmɛnt Yunit (ETU). Ɔ kɔl di Nashɔnal Pɔyzin Infɔmeshɔn Sɛnta na di Kɔlɔmbɔ Nashɔnal Ospital fɔ advays.

Sɔm sayd ɛfɛkt dɛn we pɔsin kin gɛt we yu de tek di mɛrɛsin

Jɔs lɛk ɛni mɛrɛsin, sɔm pɔsibul sayd ɛfɛkt dɛn de we yu de tek Maralixibat. Sɔm pan dɛn tin ya kin rili siriɔs, so i impɔtant fɔ no bɔt dɛn.

Ɔda tin dɛm wae kin miks wit di mɛrɛsin

Sɔm ɔda mɛrɛsin dɛn we yu de tek kin afɛkt di we aw Maralixibat de wok. So, i impɔtant fɔ tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek (inklud vaytamɛn, ɛbul mɛrɛsin, ɛn sɔpɔtmɛnt). Tek tɛm mɔ wit dɛn mɛrɛsin ya:

• di rεsin dεm we de biεn di bayl asid: fכ egzampl, kכlestayramin, kolεvεlam, kכlεstipol.
• Sɔm mɛrɛsin dɛn we dɛn kin yuz fɔ ridyus kɔlɔstrel: fɔ ɛgzampul, atorvastatin, lovastatin, simvastatin.

Aw yu kin kip ɛn pul di mɛrɛsin?

• Fɔ kip am: Kip di mɛrɛsin bɔtul na say we sef usay pikin ɛn animal dɛn we yu lɛk nɔ go ebul fɔ rich. Stɔr na rum tɛmpracha (bitwin 20-25 digri sɛlshiɔs). Di tin we impɔtant pas ɔl na fɔ trowe ɛni mɛrɛsin we lɛf 45 dez afta yu opin di bɔtul.
• Aw fɔ trowe am: Fɔ trowe mɛrɛsin dɛn we dɔn pas ɔ we yu nɔ want, aks yu famasi ɔ ɔspitul bɔt wan program we go tek dɛn. If nɔto so, chɛk di lɛbl fɔ si if i fayn fɔ trowe di mɛrɛsin na di dɔti.Nɔ ɛva flush mɛrɛsin dɔŋ di tɔylɛt if yu nɔ go to yu dɔktɔ fɔs. If yu go trowe am na dɔti, pul di mɛrɛsin kɔmɔt na di bɔtul, miks am wit sɔntin lɛk kɔfi grɔn we yu dɔn yuz, smɔl dɔti, ɔ pusi dɔti, ɛn put am insay bag we dɛn tayt tayt ɛn trowe am na di dɔti.