Mifepristone pils fɔ Cushing in sindrom? Lɛ wi tɔk bɔt dis!

Yu gɛt di sik we dɛn kɔl Cushing Syndrome ? Ɔ pɔsin we yu sabi gɛt dis sik? Wetin kin apin insay dis kes na dat wi bɔdi kin mek mɔ ɔmon kɔtisol pas aw i nid, we kin mek di blɔd shuga lɛvɛl , dat na, glukɔs, go ɔp. So, wan pan di mɛrɛsin dɛm we dɔktɔ dɛn kin kɔmɛnt pan tɛm lɛk dis na Mifepristone. Tide, wi go tɔk bɔt dɛn Mifepristone pils ya ditayli.

Us kayn mɛrɛsin na Mifepristone?

Fɔ tɔk am simpul wan, dɛn kin yuz Mifepristone pils mɔ fɔ kɔntrol di glukɔs we de na yu blɔd if yu gɛt Cushing’s Syndrome , we na wan sik we kin apin we di ɔmon kɔtisol na yu bɔdi go ɔp tumɔs.

Yu no se dis ɔmon we dɛn kɔl kɔtisol rili impɔtant fɔ wi bɔdi? We wi strɛs, wi bɔdi kin rɛdi insɛf fɔ dil wit am tru dis ɔmon. Fɔ ɛgzampul, we di bɔdi nid mɔ ɛnaji wantɛm wantɛm, dis kɔtisol kin ɛp fɔ mek mɔ shuga kɔmɔt na di blɔd. Bɔt we dis kin bɔku we pɔsin nɔ ebul fɔ kɔntrol, difrɛn prɔblɛm dɛn kin kam. di mifepristone pils dεm de ridyus di ifekt we di kכtisol כmon de gi, we de rεdכks di bכdi shuga lεvεl.

Sɔntɛnde, dɔktɔ kin gi dis mɛrɛsin fɔ ɔda sik dɛn. So, if yu nɔ shɔ ustɛm dis mɛrɛsin de fɔ, i go fayn fɔ aks yu dɔktɔ ɔ di fama na di famasi usay yu de tek yu mɛrɛsin. Dɛn kin kɔl dis mɛrɛsin bak na di makit wit di brand nem Korlym .

Wetin na di tin dɛm we a nid fɔ tɛl di dɔktɔ bifo a tek dis mɛrɛsin?

Bifo yu bigin fɔ yuz Mifepristone tablɛt, sɔm impɔtant tin dɛn de we yu fɔ rili tɛl yu dɔktɔ. Bikɔs, pipul dɛn we gɛt sɔm kayn mɛrɛsin ɔ di wan dɛn we de tek ɔda mɛrɛsin fɔ rili tek tɛm we dɛn de gi Mifepristone. Si if dɛn tin ya apin to yu:

• Yu gɛt prɔblɛm we de mek yu blɔd ?
• Yu gɛt kansa naw ɔ yu de du tritmɛnt fɔ am?
• Yu de sɔfa wit maynd sik lɛk pwɛl hat ?
• Yu gɛt ɔda kayn dayabitis we nɔ gɛt natin fɔ du wit di sik we dɛn kɔl Cushing?
• At sikYu gɛt at sik?
• Yu gɛt ay blɔd prɛshɔn ?
• Yu gɛt ɛni sik na yu liva?
• Dɔktɔ dɛn dɔn tɛl yu se di potashɔm we de na yu blɔd nɔ bɔku?
• Yu dɔn ɛva gɛt ɔgan transplant?
• Naw yu de tek stεroyd lεk dexamethasone כ prednisone?
• Yu gɛt blɔd we de kɔmɔt na yu vagina we yu nɔ ɛksplen?
• Yu dɔn ɛva gɛt alɛji fɔ mifepristone, ɛni ɔda mɛrɛsin, it, it day, ɔ tin dɛn we de mek yu nɔ pwɛl?
• Yu de tray fɔ gɛt bɛlɛ naw? Ɔ yu dɔn gɛt bɛlɛ?
• Yu na mama we de gi pikin in bɛlɛ? (Fɔ gi pikin in mama in bɛlɛ) .

If yu gɛt dis sik, i go fayn fɔ mek yu tɛl yu dɔktɔ bɔt am ɛn nɔ ayd ɛnitin .

Aw a fɔ yuz dis mɛrɛsin?

Dɛn Mifepristone tablɛt ya fɔ tek wit wata. I rili impɔtant fɔ tek dis mɛrɛsin di sem tɛm ɛvride , lɛk aw dɛn rayt am na di prɛskrishɔn lɛbl. Nɔ brok, krɔs, ɔ chew dɛn tablɛt ya. Swɛla di tablɛt ɔl wit wata.

Wan ɔda impɔtant tin na dat, dɛn fɔ tek dis mɛrɛsin wit it. Dɔn bak, nɔ tek dis mɛrɛsin wit grep jus fɔ ɛni rizin. Yu fɔ kɔntinyu fɔ yuz dis mɛrɛsin lɛk aw dɛn tɛl yu te yu dɔktɔ tɛl yu fɔ stɔp.

We di famasi gi yu dis mɛrɛsin, dɛn go gi yu wan smɔl buk we gɛt spɛshal instrɔkshɔn bɔt dis mɛrɛsin, we dɛn kɔl MedGuide . I rili impɔtant fɔ rid ɛn ɔndastand dis MedGuide liflet fayn fayn wan ɛvri tɛm we yu tek di mɛrɛsin, ɛn we yu gɛt rifil.

If yu de gi dis mɛrɛsin to yɔŋ pikin dɛn, mek shɔ se yu tɔk to yu dɔktɔ bɔt am, bikɔs i kin nid spɛshal dɔktɔ we de kia fɔ am ɛn kia fɔ am.

Wetin fɔ du if yu tek di mɛrɛsin pasmak?

If yu tink se yu dɔn tek dis mɛrɛsin tumɔs, kɔl di pɔyzin kɔntrol sɛnta we de nia yu ɔ di imejensi rum na pɔblik ɔspitul wantɛm wantɛm fɔ advays.

Mɛmba bak: Dɛn dɔn gi yu dis mɛrɛsin fɔ yu nɔmɔ. Nɔ gi am to yu padi ɔ yu fambul fɔ ɛni rizin, ilɛksɛf dɛn gɛt di sem sayn lɛk yu.

Wetin fɔ du if yu mis wan doz fɔ mɛrɛsin?

If yu fɔgɛt fɔ tek wan Mifepristone pil wan de, tek am jɔs lɛk aw yu mɛmba. Bɔt if i dɔn lɛf smɔl fɔ lɛ yu tek yu nɛks doz we yu mɛmba, skip di doz we yu mis ɛn tek yu nɛks doz di tɛm we yu dɔn sɛtul. Nɔ ɛva tek dɛbul ɔ ɛkstra doz, dat min se, tek ɔl tu di doz we yu mis ɛn di wan we yu fɔ dɔn tek di sem tɛm. We yu du dat, dat kin mek yu gɛt mɔ sayd ɛfɛkt.

Us ɔda mɛrɛsin dɛn we yu nɔ fɔ tek wit dis mɛrɛsin?

If yu de tek ɛni wan pan dɛn mɛrɛsin ya naw, nɔ ɛva tek dɛn togɛda wit Mifepristone. Dɛn tin ya kin mek pɔrsin gɛt siriɔs, denja intarakshɔn wae kin mek pɔrsin in layf de pan denja:

• Sɔm mɛrɛsin dɛn we dɛn kin yuz fɔ mɛn fungal infɛkshɔn, fɔ ɛgzampul, fluconazole, ketoconazole, ɛn posaconazole.
• Dɛn kin gi sɔm mɛrɛsin fɔ mek di kɔlɔstrel we de na di blɔd go dɔŋ, fɔ ɛgzampul lovastatin ɛn simvastatin.
• Cisapride we dɛn kɔl Cisapride
• Sayklɔspɔrin we dɛn kɔl
• Dronedarone we gɛt di sik
• εrgכt alkaloyd dεm, fכ egzampl, dihaydro εrgotamin εn εrgotamin.
• Fɛntanyl we dɛn kɔl
• Pimozayd we dɛn kɔl Pimozide
• Kwinidin we dɛn kɔl
• Sirolimus we de na di wɔl
• Takrɔlimus we dɛn kɔl
• Tioridazin we dɛn kɔl Tioridazin

Dis list nɔr de ɔlsay, so i rili impɔtant fɔ tɛl yu dɔktɔ bɔt ɛvri mɛrɛsin we yu de tek, ivin di vaytamɛn dɛn.

Ɔda mɛrɛsin ɛn tin dɛn we kin miks wit dɛnsɛf

Ɔda mɛrɛsin ɛn tin dɛn de we kin intarakt wit Mifepristone, so i fayn fɔ no bɔt dɛn tin ya bak:

• Sɔm kayn antibayɔtik, fɔ ɛgzampul klarithromycin, erythromycin, telithromycin.
• Dɛn kin gi sɔm antivayrɔs mɛrɛsin fɔ HIV infɛkshɔn ɔ liva sik lɛk ɛpatitis.
• Mεdisin dεm we dεn kin yus fכ trit di nεv sεstem kכndyushכn dεm lεk we yu de sik, fכ egzampl carbamazepine, phenytoin, εn phenobarbital.
• Sɔm mɛrɛsin dɛn we de mek blɔd nɔ klot, fɔ ɛgzampul, warfarin.
• Kɔnivaptan we dɛn kɔl
• Grepfruit jus – As wi bin dɔn tɔk, dis na sɔntin we nɔ fayn fɔ it we yu de tek Mifepristone.
• Ɔmon bɔn kɔntrol pils, injɛkshɔn, pat ɛn divays dɛn we gɛt ɔmon.
• Itrakonazɔl we dɛn kɔl
• Mɛrɛsin fɔ mɛn yu maynd lɛk pwɛl hat ɔr wae yu de wɔri bad bad wan.
• Dɛn kin gi sɔm nakotik mɛrɛsin dɛn as mɛrɛsin fɔ mek pɔsin fil pen.
• Ɔda mɛrɛsin dɛn we kin mek di at nɔ ritm, lɛk di wan dɛn we kin mek di QT intaval lɔng.
• Repaglinid we dɛn kɔl
• Rifabutin, Rifampin, Rifapentin, ɛn ɔda pipul dɛn.
• Sɛnt Jɔn wɔt na ɛbul sɔpɔtmɛnt.
• Stɛroyd mɛrɛsin dɛn, lɛk prɛdnison ɔ kɔtizɔn.
• Tayrɔyd ɔmon dɛn.
• Vorikonazɔl we dɛn kɔl Voriconazole.

Sɔntɛm dis list nɔ go gɛt ɔltin. So, mek shɔ se yu tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn, ɔyl dɛn, mɛrɛsin dɛn we yu nɔ de tek, ɛn di it dɛn we yu de tek . Dɔn bak, tɛl yu dɔktɔ if yu de smok, drink rɔm, ɔ yuz drɔgs we nɔ rayt. Dɛn tin ya kin intarakt wit di Mifepristone we yu de tek.

Wetin na de tin wae yu fɔ tek tɛm wit we yu de tek dis mɛrɛsin?

We yu de tek Mifepristone, yu go nid fɔ go to yu dɔktɔ fɔ mek dɛn chɛk yu ɔltɛm fɔ wach yu wɛlbɔdi. Yu dɔktɔ kin tɛl yu bak fɔ mek dɛn du sɔm blɔd wok.

Dis mɛrɛsin kin afɛkt di blɔd shuga lɛvɛl. If yu gɛt dayabitis, mek shɔ se yu tɔk to yu dɔktɔ bifo yu mek ɛni chenj pan yu it ɔ di doz fɔ yu dayabitis mɛrɛsin.

Kip di spɛshal instrɔkshɔn liflet fɔ dis mɛrɛsin, we dɛn kɔl MedGuide, fayn fayn wan. If yu nid imejensi mɛdikal kia, sho di MedGuide liflet to di mɛdikal tim. Tɛl dɛn bak se yu de tek Mifepristone.

Tin dɛn we uman dɛn fɔ tek tɛm mɔ bɔt:

• Yu fɔ tek bɛlɛ tɛst fɔ kɔnfirm if yu gɛt bɛlɛ bifo yu bigin dis Mifepristone mɛrɛsin. Nɔ gɛt bɛlɛ we yu de tek dis mɛrɛsin ɔ fɔ wan mɔnt afta yu dɔn stɔp di mɛrɛsin.
• If yu de plan fɔ gɛt bɛlɛ ɔ yu tink se yu go gɛt bɛlɛ, tɛl yu dɔktɔ wantɛm wantɛm. Dis mɛrɛsin kin mek di pikin we nɔ bɔn yet gɛt siriɔs sayd ɛfɛkt. Aks yu dɔktɔ fɔ no mɔ.
• Yu fɔ yuz fayn fayn bɔn kɔntrol we yu de tek Mifepristone. Nɔn-ɔmon bɔn kɔntrol bɛtɛ we yu de tek dis mɛrɛsin ɛn fɔ wan mɔnt afta yu dɔn stɔp di mɛrɛsin. Tɔk to yu dɔktɔ bɔt di bɛst we fɔ mek yu nɔ gɛt bɛlɛ. If yu tink se yu gɛt bɛlɛ, tɛl yu dɔktɔ wantɛm wantɛm.

Fɔ mama dɛn we de gi pikin in bɛlɛ: Nɔ gi yu pikin in bɛlɛ we yu de tek dis Mifepristone mɛrɛsin.

Wetin na di sayd ɛfɛkt dɛm we dis mɛrɛsin kin gɛt?

Lɛk ɔl di mɛrɛsin dɛn, Mifepristone kin mek sɔm sayd ɛfɛkt dɛn. Sɔm sayd ɛfɛkt dɛn de we yu fɔ tɛl yu dɔktɔ wantɛm wantɛm if dɛn apin. Dɛn na:

• Alɛji: Skin de rɔsh, it, ayv, swel na yu fes, lip, tɔng, ɔ trot. Dɛn tin ya kin denja.
• di at ritm de chenj: di at de bit fast ɔ i nɔ de bit ɔltɛm, diziz, fil fɔ fil fayn ɔ layt ed, chɛst de pen, trɔbul fɔ blo.
• Fɔ uman dɛn: I nɔ kin gɛt mɔnt ɔ blɔd kin kɔmɔt we nɔ kɔmɔn (spɔt) we dɛn de gɛt mɔnt.
• Di sayn dɛm we de sho se di adrenal gland nɔ de wok fayn: yu de nɔs, yu de vɔmit, yu nɔ de want fɔ it, yu wik ɔ taya we nɔ kɔmɔn, yu de tɔn diziz.
• Di sayn dɛm we de sho se di potashɔm nɔ de na di blɔd: di mɔsul dɛn de pen ɔ kramp, fil wik ɔ taya pasmak, at bit fast ɔr nɔr de bit ɔltɛm, kɔnstipɛshɔn.

Bɔrku tɛm, di sayd ɛfɛkt dɛm wae de dɔŋ ya nɔr kin siriɔs, bɔt if dɛn kɔntinyu ɔr de mɔna yu, tɛl yu dɔktɔ:

• Diziz we pɔsin kin gɛt
• Taya
• Ed de at
• Pen na di jɔyn dɛn
• I nɔ kin want fɔ it igen
• Vɔmit
• Di anklɛ, an, ɔ fut kin swel.

Dis list nɔr de inklud ɔl di poshubul sayd ɛfɛkt dɛm fɔ Mifepristone. If yu gɛt ɛni sayn we nɔ kɔmɔn, tɛl yu dɔktɔ. Yu kin ripɔt bak di sayd ɛfɛkt dɛn to di US Food and Drug Administration (FDA) na 1-800-FDA-1088.

Aw a fɔ kip mi mɛrɛsin?

Kip dis Mifepristone mɛrɛsin na say we sef usay smɔl pikin ɛn animal dɛn we dɛn kin mɛn nɔ go ebul fɔ rich . Stɔ am na rum tɛmpracha, bitwin 20 ɛn 25 digri sɛlshiɔs (68 ɛn 77 digri F. Chek di de we di mɛrɛsin dɔn ɛn nɔ ɛva yuz ɛni mɛrɛsin we dɔn dɔn. Trowe am fayn fayn wan.

Aw yu kin trowe mɛrɛsin dɛn we dɛn nɔ nid igen ɔ we dɔn dɔn ɛn we nɔ go ambɔg di envayrɔmɛnt?

• Sɔm famasi ɔ ɔspitul dɛn gɛt program fɔ tek mɛrɛsin bak. If i pɔsibul, tek yu mɛrɛsin to wan pan dɛn ples ya. Yu kin no mɔ bɔt dis na yu famasi ɔ lokal pɔblik wɛlbɔdi inspɛktɔ.
• If no we nɔ de fɔ gi am bak, chɛk di mɛrɛsin paket ɔ di instrɔkshɔn dɛn we de insay fɔ si if dɛn fɔ trowe am na dɔti ɔ flɔsh am dɔŋ di tɔylɛt. If yu nɔ shɔ, aks yu dɔktɔ ɔ fama.
• If yu kin trowe dɛn na dɔti, pul di pils dɛn na di bɔtul ɔ paket, miks dɛn fayn fayn wan wit pusi dɔti we yu dɔn yuz, sɔm dɔti, grɔn kɔfi grɔn, ɔ ɔda tin dɛn we tan lɛk dat we yu nɔ want. Dɔn, put dis miksɔp insay wan pɔlitɛn bag ɔ plastic kɔntena we yu kin sial bak, sial am fayn fayn wan, ɛn trowe am na di dɔti.

Fɔ dɔn, tin dɛn we wi fɔ mɛmba

Okay, so naw yu ɔndastand se Mifepristone na impɔtant mɛrɛsin we kin ɛp fɔ kɔntrol di blɔd shuga lɛvɛl fɔ pɔsin lɛk yu we gɛt Cushing Syndrome. Bɔt yu si bak se bɔku tin dɛn de we yu fɔ rili tek tɛm wit we yu de yuz am.

Na mɔtalman, i rili impɔtant fɔ tɛl yu dɔktɔ klia wan bɔt ɔda mɛrɛsin dɛn we yu de tek ɛn ɔda sik dɛn we yu gɛt, fɔ tek di mɛrɛsin jɔs lɛk aw di dɔktɔ se, di tɛm ɛn di mɔnt we dɛn tɛl yu fɔ tek, fɔ no bɔt di bad tin dɛn we kin apin to yu, ɛn fɔ tek tɛm mɔ bɔt di bɛlɛ ɛn kɔntrol we yu de bɔn pikin.

If yu gɛt ɛni kwɛstyɔn ɔ dawt bɔt dis mɛrɛsin, nɔ ɛva shem fɔ aks yu dɔktɔ ɔ fama na di famasi fɔ sɔlv am. Mɛmba se yu wɛlbɔdi rili impɔtant to yu!

` Mifepristone, Cushing’s syndrome, kɔtisol, blɔd shuga, adrenal gland, drɔg intarakshɔn, sayd ɛfɛkt