Yu tink se tumbu dɛn kin kam na yu nerv dɛn? Lɛ wi tɔk bɔt Nerve Sheath Tumors insay simpul wɔd dɛn!

Di nɛv dɛn we de rɔn ɔlsay na wi bɔdi tan lɛk wan nɛtwɔk we gɛt waya dɛn we de kɛr ilɛktrik mɛsej dɛn. na dεn de kכri infכmeshכn bak εn go bifo frכm di bren to di rεst כf di bכdi, εn frכm di bכdi to di bren. Imajin se dɛn nɛv sɛl dɛn ya, we na dɛn grup dɛn, dɛn ɔl rap insay spɛshal tin dɛn we de protɛkt dɛn, lɛk di plastic sheath we de rawnd waya, fɔ protɛkt dɛn ɛn ɛp di ilɛktrik signal dɛn fɔ travul fast fast. na insay dεn mεmbran dεm ya we de protεkt sכmtεm dεn tin ya we dεn kכl nεv sεt tכmכro dεm de divεlכp.

Wetin na di Nɛv Shit Tumɔs?

fכ simpul wan, dεn tכmכro dεm ya de fכm insay di prכtektiv "sheaths" dεm we de rawnd wi nεv dεm. Dis "sheath" ɔ kɔva na sɔm layers:

• Schwann sel dεm: Dis na di sεl dεm we de rap rawnd di aksכn, di lכng pat pan di nεv sεl, lεk insulεshכn rawnd waya.
• endoneurium: Dis na di kכnektiv tisu we de rawnd εvri nεv fayba, lεk di sεt we de rawnd wan singl kכpa waya insay waya.
• Perineurium: Dis na wetin de rawnd di bכndεl dεm fכ di nεv fayb dεm.

Wi nervɔs sistɛm kin sheb to tu pat:

• Sεntri nεv sεstem: Dis inklud wi bren εn spεnal kכd.
• di pεrifεral nεv sεstem: dis na di nεtwכk fכ di nεv dεm we de branch kכmכt frכm di bren εn spεnal kכd to כl di pat dεm na di bכdi.

Bɔku tɛm, dɛn nyurofibroma ya kin fɔm na di periferik nɛvɔ sistɛm .

Us kayn nɛt dɛn de?

Bɔku men kayn nyuroma dɛn de. Lɛ wi tek wan luk pan wetin dɛn bi.

Schwannomas bin de tɔk bɔt am

dis tכmכro dεm de divεlכp na di Schwann sεl dεm we wi bin dכn tכk bכt. כlmost 60% pan di schwannomas de divεlכp na di vεstibular nεv na wi insay yes . Dis nerve de ɛp wi bɔdi fɔ balans. Ɔda schwannomas kin kam sɔmtɛm ɔnda wi skin, ɔr dip insay di tisu ɛn ɔgan dɛm na di bɔdi. di ples dεm we dεn kin si dεn tכmכro dεm ya na:

• Na di an ɛn di leg dɛn
• Na di ed
• insay di trכnk (dat na di εria bitwin di sכlda dεm εn di hip dεm) .

Schwannomas na wan kayn tכmכro we kin kכba wit wan tin layεr fכ tisu, כ "encapsulated." Dɛn tumbu ya nɔ kin gɛt kansa (benign). Bɔt, na smɔl tɛm nɔmɔ, wan tumbu we dɔn de fɔ lɔng tɛm kin bi kansa (malignant).

Nyurofibroma dɛn

dis kayn tכmכro involv sεvεra kayn tisu dεm we dεn kכl Schwann sεl dεm, εndoneurium, εn perineurium we de kכba di nεv dεm. dis kin apin lεk lumps כnda di skin, bכt sכmtεm dεn kin divεlכp pan di nεv dεm we de dip insay di bכdi.

difrεnt lεk schwannomas, nyurofibromas nכ de insay kapsul. Dɛn kin gro insay di nerve bundles. Plexiform neurofibromas na wan kayn tכmכro we de spre lεk mεsh, we de rawnd plεnti nεv bכndεl dεm εn i kin spre insay di tisu dεm we de rawnd am.

Bɔku pan di nyurofibroma dɛn nɔto kansa. Bɔt lɛk 5% to 10% pan dɛn tɔŋ ya kin bi kansa . Dɛn kɔl dɛn malignant peripheral nerve sheath tumors (MPNST) . Na lɛk af pan di pipul dɛn we gɛt dɛn bad bad tumbu ya dɔn ɔlrɛdi spre to ɔda pat dɛn na dɛn bɔdi bay di tɛm we dɛn no se dɛn gɛt am.

Aw kɔmɔn dis frut?

di tכmכro dεm we nכ de fכ di nεv sεt we nכ kכnεs nכ kin bכku.

• Dɛn kin si Schwannomas pan pipul dɛm wae ol bitwin 50 ɛn 60 ia.
• Nyurofibromas kin apin mɔ pan pipul dɛn we ol bitwin 20 ɛn 40 ia.
• di pleksifכm nyurofibroma dεm kin divεlכp bifo dεn rich 5 ia.

Malignant Peripheral Nerve Sheath Tumors na wan kayn kansa wae nɔr kin bɔrku , ɛn na lɛk wan pan ɔl 10 milyɔn pipul dɛm nɔmɔ kin afɛkt ɛvri ia.

Wetin mek tumbu dɛn lɛk dis kin fɔm? Wetin na di tin dɛn we kin mek i apin?

di jεnεtik chenj dεm gεt big impak pan di divεlכpmεnt fכ dεn nyurofibroma dεm ya.

• di divεlכpmεnt fכ Schwannomas de sho se di chenj dεm na di jin we dεn kכl NF2.
• Nyurofibroma dɛn gɛt fɔ du wit wan jin we dɛn kɔl (NF1).

Bɔku tɛm, dɛn chenj ya we kin apin na di jɛnɛtiks kin apin wan wan tɛm, ɛn dɛn nɔ kin si ɛni rizin . Bɔt smɔl nɔmba pan schwannomas ɛn nyurofibromas kin kɔmɔt frɔm wan jɛnɛtik kɔndishɔn we nɔ kin bɔku we dɛn kɔl nyurofibromatosis , we kin rɔn na famili.

Tayp dɛn fɔ Nyurofibromatosis

Tri men kayn dis sik de:

• Nyurofibromatosis tayp 1 (NF1): Pipul dεm we gεt NF1 de divεlכp bכku nyurofibroma dεm. dεn gεt bak inkrεs risk fכ divεlכp pleksifכm nyuromas εn malign pεrifεral nεv shεt tכmכro (MPNST). Ɔda tin dɛn we dɛn kin si pan pipul dɛn we gɛt NF1 na makrosɛfali , skɔliosis, ɛn disabiliti fɔ lan .

• Nyurofibromatosis tayp 2 (NF2): .Klose to ɔlman we gɛt NF2 kin gɛt vestibular schwannomas na dɛn tu yes bifo dɛn rich 30. pan tap dat, ɔda kayn schwannomas ɛn tumor kin kam bak na dɛn skin, yay, ɛn sɛntral nervous system.

• Schwannomatosis: insay dis kכndishכn, mכltipכl schwannomas de divεlכp na di vεstibular nεv (insay di tu yes dεm) pas na di vεstibular nεv.

Wetin na di sayn dɛm fɔ dɛn tumbu ya?

Bɔrku pipul dɛm wae gɛt nyuromastoid tumor nɔr kin gɛt ɛni pen ɔr ɔda sayn dɛm . Bɔt if di tumbu gro big ɔ prɛs pan wan nɛv, sɔm sayn dɛn lɛk:

• Lump ɔ tumor ɔnda di skin (i kin mek yu fil pen we yu prɛs am).
• Di mɔsul dɛn we wik .
• Fɔ mek pɔsin nɔ ebul fɔ du natin .
• Pen, pen, ɔ shap pen .
• Wan tin we kin mek pɔsin fil lɛk se i de swɛt, lɛk we ilɛktrishɔn de bit am .

dipכnt pan usay di tכmכro de, כda spεshal simptom dεm kin apin bak. Na sɔm ɛgzampul dɛn ya:

• wan tכmכro na di sciatic nerve: Pen we de travul frכm di bak dכn di leg (sciatica).
• Wan tumbu na di an: Di sayn dɛm we fiba di wan dɛm we gɛt Carpal Tunnel Syndrome.
• Vestibular nerve tumor: Yu nɔ de yɛri fayn, yu kin gɛt tinnitus, yu kin gɛt prɔblɛm wit balans.

Bɔku tɛm, if pɔsin gɛt nyurofibromatosis, na wan tumbu. כltu, pan pipul dεm we gεt di kכndyushכn we wi bin dכn tכk bכt nyurofibromatosis, dεn kin si mכltipכl tכmכro dεm (bכku tεm na di skin).

Aw yu go no if yu gɛt dɛn nɛt ya?

Yu dɔktɔ go fɔs chɛk yu bɔdi ɛn asɛs yu ɔl wɛlbɔdi. Dis go inklud fɔ aks bɔt yu mɛdikal histri, yu famili mɛdikal histri, ɛn ɛni sayn we yu go gɛt.

Fɔ mek yu go ebul fɔ no mɔ bɔt wan tumbu we yu dɔn ɔlrɛdi si ɔ we yu tink se gɛt tumbu, yu dɔktɔ kin tɛl yu fɔ du dɛn tɛst ya:

• Mɛdikal imej tɛst: Dɛn tin ya na MRI skan, ɔltra saund skan, ɛn PET skan fɔ si di tumbu klia wan.
• Bayopsi: Dɛn kin tek wan smɔl tisu frɔm di tɔŋ ɛn chɛk am ɔnda maykroskɔp fɔ no us kayn sɛl dɛn de. Dis na wetin kin tɛl yu fɔ tru if di tumbu gɛt kansa ɔ nɔ gɛt kansa.

If yu gɛt bɔku bɔku tumbu, yu dɔktɔ kin tɛl yu bak fɔ du yu jenɛtik tɛst fɔ si if yu gɛt tin dɛn we dɛn kɔl (NF1), (NF2), ɛn Schwannomatosis.

Wetin na di tritmɛnt dɛm fɔ dis?

If yu nɔr gɛt ɛni simptom frɔm nyuromastoid, yu dɔktɔ kin se yu fɔ "watch ɛn wet."Yu kin go wit di we aw dɛn kɔl "monitoring." Dat min se yu fɔ chɛk di tumbu ɔltɛm fɔ si if i de big ɔ i de chenj.

Fɔ di tumbu dɛn we gɛt sɔm sayn dɛn, ɔ if yu want fɔ pul di tumbu fɔ kɔsmɛtik rizin, bɔku tɛm na ɔpreshɔn na di wangren tin we yu kin du .

sכm nyurofibroma dεm, spεshal wan dεm we dεn kכl plexiform nyurofibromas, i at fכ pul dεm kכmplit biכs dεn de gro insay di nεv εn bitwin di layεr dεm na di kכva. If dɛn nɔ ebul fɔ pul di tumbu ɔl afta dɛn dɔn du di ɔpreshɔn, yu dɔktɔ go de wach yu gud gud wan, bikɔs di tumbu kin gro bak.

Tritmɛnt fɔ schwannomas na di ed

Schwannomas we de fכm na di ed, lεk vestibular schwannomas, kin afekt di nεv dεm we de kכntrol imכtant wok dεm na wi bכdi. Insay dɛn kayn tin ya, dɔktɔ dɛn kin yuz wan we we dɛn kɔl stereotactic radiosurgery (e.g., Gamma Knife®) fɔ mek di nerv dɛn nɔ pwɛl.

Dis nɔto tradishɔnal ɔpreshɔn we gɛt fɔ du wit fɔ kɔt kɔt. I involv fɔ sɛn wan rili prɛsis targeted bim ɔf raytin tru di skin fɔ pwɛl ɔ shrink di tumor.

Tritmεnt fכ kansa pεrifεral nεv sεt tכmכro dεm

Apat frɔm ɔpreshɔn, dɛn kin yuz kansa tritmɛnt dɛn lɛk redyushɔn tɛrapi ɛn kemotɛrapi bak fɔ trit di bad bad periferik nɛv swɛt tumbu dɛn.

Wetin na di prɔblɛm dɛn we kin apin we pɔsin du ɔpreshɔn?

Jɔs lɛk ɛni ɔpreshɔn, sɔm kɔmɔn prɔblɛm dɛn de we kin apin wit dɛn ɔpreshɔn ya:

• Blɔd we de kɔmɔt
• Infekshɔn na wund
• Pen
• Skaring we de mek pɔsin gɛt skata

Apat frɔm dat, di ɔpreshɔn we dɛn kin du na di nerv kin mek di nerv pwɛl ɛn i kin gɛt disabled fɔ ɔltɛm . Yu mɛdikal tim go ɛp yu fɔ manej ɛni lɔng tɛm disabiliti we kin kam afta dɛn dɔn ɔpreshɔn yu. Difrɛn tritmɛnt dɛn (fyzikal tritmɛnt, wok tritmɛnt, ɛn tɔk tritmɛnt) kin ɛp yu fɔ wɛl.

Dɛn kin mek dɛn tumbu ya nɔ fɔm?

No we nɔ de we dɛn no fɔ mek dɛn tumbu ya nɔ fɔm. Bɔt yu dɔktɔ go tɛl yu fɔ du tɛst fɔ yu jɛnɛtiks if yu:

• If ɛnibɔdi na yu famili gɛt histri fɔ gɛt nyurofibromas.
• If yu gɛt bɔku bɔku nerve sheath tumor (dis kin bi sayn fɔ di kɔndishɔn nyurofibromatosis).

Wetin wi fɔ tink bɔt dɛn nɛt ya fɔ go bifo? (Autluk) .

Bɔku pan di nyurofibroma dɛn nɔ kin gɛt kansa . Dɛn kin wɛl wit ɔpreshɔn ɛn dɛn nɔ kin kam bak. Bɔt if dɛn nɔ ebul fɔ pul yu tumbu ɔltogɛda wit ɔpreshɔn, yu go nid fɔ kɔntinyu fɔ de ɔnda dɔktɔ.

Na lɛk 3 pan 4 pipul dɛm wae gɛt tritmɛnt fɔ vestibular schwannoma kin ebul fɔ kip dɛn yɛri .

Di risk fɔ mek di nerve sheath tumor bi kansa rili smɔl. di hεy risk na fכ pipul dεm we gεt di kכndyushכn (NF1) we de divεlכp Plexiform neurofibroma. di prכgnosis fכ di malignant pεrifεral nεv sεt tכmכro dεm (MPNST) nכ gud, spεshal if di tכmכro big pas 2 inch. Nɔr to af pan pipul dɛm wae gɛt dis sik kin liv fayv ia afta dɛn dɔn no bɔt dis sik.

Ustɛm yu fɔ go to dɔktɔ?

If yu notis wan lump ɔnda yu skin, ɔ yu gɛt ɛni sayn we yu tink se kin bi nyurofibromatosis , go to dɔktɔ wantɛm wantɛm . Dɔn bak, tɛl yu dɔktɔ if ɛnibɔdi na yu famili dɔn gɛt dɛn kayn tumbu ya.

Faynal Mɛsej fɔ Tek-Hom

Mɛmba se bɔku pan di nyuro ɛndɔkrin tɔŋ dɛn na fayn fayn tin dɛn we nɔ gɛt kansa ɛn we de gro sloslo . If yu nɔ gɛt ɛni sayn, yu dɔktɔ go disayd fɔ jɔs wach yu. If dɛn nid fɔ pul wan tumbu, bɔku tɛm di ɔpreshɔn kin rili fayn. I nɔ kin izi fɔ mek kɔmplikeshɔn (lɛk fɔ nɔ ebul fɔ pul di tɔŋ kpatakpata, fɔ mek di nerv pwɛl) ɔ fɔ mek di tumbu tɔn kansa. Yu dɔktɔ go ɛp yu fɔ mek wan tritmɛnt plan ɛn wan schedule fɔ tɛst dɛn tumara bambay fɔ ɛp yu fɔ kɔntrol yu sik. So nɔ fred fɔ tɔk to yu dɔktɔ bɔt ɛnitin.

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