Na nɔmal tin fɔ fil bɔku frayd ɛn wɔri we yu dɔktɔ tɛl yu se sɔmbɔdi na yu famili, sɔntɛm yu mama ɔ papa we yu lɛk, gɛt dis sik we dɛn kɔl Pakinsin. Pan ɔl we dɛn nɔ stil gɛt mɛrɛsin fɔ dis sik, bɔku fayn mɛrɛsin dɛn de we go ɛp fɔ kɔntrol di sik dɛn ɛn fɔ mek i gɛt gud kwaliti layf. So tide, lɛ wi tɔk bɔt wetin na dɛn mɛrɛsin ya, aw dɛn de wok, ɛn wetin wi nid fɔ no bɔt.
Wetin mek di sik we dɛn kɔl Parkinson kin apin? Wetin kin apin wit mɛrɛsin?
Fɔ tɔk am simpul wan, di sik we dɛn kɔl Parkinson na wan sik we de kam bifo pan di nyurolɔjik we kin afɛkt di we aw di bɔdi de muv. i kin bi we di nεv sεl dεm na di bren de lכs sכmtεm, spεshal wan na di pat pan di bren we dεn kכl substantia nigra we de kכntro di muvmεnt. dis nεv sεl dεm de mek wan nyurotransmitεr we dεn kכl dopamin .
Tink bɔt am, wan kemikal we dɛn kɔl dopamine impɔtant fɔ mek wi bɔdi muv fayn fayn wan, lɛk we wi de drayv na rod we nɔ gɛt trafik jam. Insay di sik we dɛn kɔl Parkinson, di we aw dɛn de mek dis dopamin kin go dɔŋ, we kin mek i gɛt sɔm sayn dɛn lɛk fɔ muv sloslo, fɔ shek, ɛn fɔ stif.
So di men gol fɔ bɔku mɛrɛsin fɔ Pakinsin sik na fɔ sɔm kayn we fɔ kɔntrol di smɔl smɔl dopamin na di bren.
Di mɛrɛsin dɛn we dɛn kin yuz mɔ
Dɔktɔ dɛn kin gi sɔm mɛrɛsin dɛn we dɛn jɔyn togɛda fɔ di wan dɛn we gɛt Pakinsin, nɔto jɔs wan. Lɛ wi tek wan luk pan di men kayn mɛrɛsin dɛn.
| Drug Klas we dɛn de yuz | Aw I De Wok | Impɔtant tin dɛn fɔ no bɔt |
|---|---|---|
| Levodopa ɛn Kabidopa | Levodopa na wan drɔg we de go na di bren ɛn tɔn to dopamine. Bɔt bikɔs i kin pwɛl na di bɔdi bifo i rich na di bren, dɛn kin miks am wit wan mɛrɛsin we dɛn kɔl kabidopa fɔ stɔp am. | Dis na di men ɛn di bɛst mɛrɛsin fɔ di sik we dɛn kɔl Pakinsin. I rili fayn fɔ ridyus di muvmɛnt sloslo (bradykinesia), rigidity, ɛn trem. |
| Dopamin Agɔnis dɛn | dis dεm de mek di dopamin rεsεpכta dεm na di bren εn "akt" lεk dopamin. Dat min se dɛn drɔgs ya de du di sem tin we dopamin de du. | Bɔku tɛm dɛn kin yuz am we di sik bigin ɔ pan yɔŋ pipul dɛn, i kin ɛp bak fɔ mek di lɛvodopa wok fayn fɔ lɔng tɛm. |
| Enzym Inhibitor (MAO-B & COMT) Di wan dɛn we de mek di bɔdi nɔ ebul fɔ du sɔntin. | dis mεdikeshכn dεm de ridyus di aktiviti fכ di εnzym dεm na di bren we de brok dכpamin, we de mek di dopamin de na di bren fכ lכng tεm. | Dɛn kin gi dɛn tin ya fɔ ɛp fɔ mek di ifɛkt we lɛvodopa gɛt bɔku ɛn mek i las fɔ lɔng tɛm. |
| Amantadin we dɛn kɔl am | I de ɛp fɔ kɔntrol diskinesia, we na wan twitch ɔ twitching na di bɔdi we dɛn nɔ kin kɔntrol we kin kam wit mɛrɛsin lɛk lɛvodopa. | Pan ɔl we dɛn bin dɔn fɛn am fɔs as antivayral, i fayn bak fɔ ɔda muvmɛnt prɔblɛm dɛn lɛk Pakinsin sik. |
| Anticholinergic mɛrɛsin dɛn we dɛn kin yuz | we di dopamin dכn dכn, di ifekt dεm fכ כda kεmikכl we dεn kכl asetilkolin de inkrεs. Dɛn mɛrɛsin ya kin blok di tin dɛn we i kin du, we kin mek i nɔ shek ɛn di mɔsul dɛn nɔ kin stif. | I kin fayn fɔ di wan dɛn we de shek pasmak. |
Di tin we impɔtant pas ɔl na dat na yu dɔktɔ nɔmɔ go disayd uswan pan dɛn mɛrɛsin ya fɔ gi ɛn insay us doz. E kin dipen pan de pɔrsin in ej, di kayn sik wae de mɛk pɔrsin gɛt dis sik, ɛn bɔrku ɔda tin dɛm.
Yu tink se wi fɔ no bak bɔt di bad tin dɛn we di mɛrɛsin dɛn kin du?
Lɛk ɛni mɛrɛsin, di mɛrɛsin dɛn we de mek pɔsin gɛt Pakinson kin gɛt sayd ɛfɛkt. Dɛn tin ya kin difrɛn difrɛn wan bay di kayn mɛrɛsin we dɛn de tek. Nɔ wɔri, nɔto ɔlman go gɛt ɔl dɛn sayd ɛfɛkt ya. Bɔt i impɔtant fɔ no bɔt dɛn.
- Levodopa: Nɔs, vɔmit, diziz, ed pen, slip de, ɛn postural hypotension kin apin ali di tritmɛnt. Na ol pipul dɛm, kɔnfyushɔn, hallucination, ɔr saykosis kin apun.
- Dopamine Agonists: Dɛn tin ya kin mek yu nɔs, yu kin slip, yu mɔt kin dray, yu kin kɔnfyus, ɛn yu kin si tin dɛn we yu de si we yu fɔs bigin fɔ tek dɛn. Bɔt, dɛn sayn ya kin stɔp insay sɔm dez.
- Ɔda mɛrɛsin dɛn: Sɔm mɛrɛsin kin mek yu gɛt sayd ɛfɛkt lɛk dayarɛa, chɛst pen, nɔr kin slip, yu leg kin swel, yu kin gɛt bɛlɛ, ɔ yu mɔt kin dray.
Wan rili impɔtant wɔnin: Nɔ ɛva stɔp fɔ tek lɛvodopa ɔ ridyus di doz wantɛm wantɛm we yu nɔ go to yu dɔktɔ. If yu du dat, i kin mek yu gɛt wan sik we rili denja, we kin mek yu layf de pan denja we dɛn kɔl Parkinsonism Hyperpyrexia Syndrome. Na siriɔs sik we fiba Nyurolɛptik Malignant Sindrom. If yu nid fɔ stɔp fɔ tek di mɛrɛsin fɔ ɛni rizin, mek shɔ se yu tɔk to yu dɔktɔ.
Dɛn gɛt mɛrɛsin fɔ ɔda sayn dɛm wae nɔr gɛt natin fɔ du wit muvmɛnt?
Yɛs. Pakinsin nɔr na jɔs wan sik wae de afɛkt aw pɔrsin de muv. Bɔt bɔku ɔda prɔblɛm dɛn de we kin kam wit am. Di dɔktɔ kin trit dɛn wan dɛn de bak.
| Di sayn we de sho se di sik de | Di Tritmɛnt dɛn we pɔsin kin gɛt |
|---|---|
| Banbɛlɛ | Mεdisin dεm we de εp fכ izi fכ stכl, lεk polyethylene glycol (lεk MiraLax). |
| Slip we pɔsin kin slip na di de | Mεdikeshכn dεm lεk Modafinil (lεk Provigil). |
| Pwɛl hat ɔ Wae yu de wɔri | SSRI-tayp antidipreshan. |
| Saykosis/Halusineshɔn | Speshal antisaykotik mεdikeshכn dεm lεk pimavanserin. |
| Erectile Dysfunction we pɔsin kin gɛt | Sildenafil (lɛk Viagra) mɛrɛsin. |
Wetin ɔda tin dɛn kin du apat frɔm mɛrɛsin?
Mɛrɛsin na jɔs wan pat pan dis fɛt. Apat frɔm dat, bɔku ɔda tin dɛn de we kin mek di pɔsin in layf bɛtɛ.
Ɛksesaiz ɛn fyzikal tritmɛnt rili impɔtant fɔ mɛn di sik we dɛn kɔl Pakinsin. Infakt, ɛksesaiz na di wangren tin we dɛn dɔn pruv se i kin mek di sik nɔ go bifo kwik kwik wan.
- Fizik tritmɛnt: Fizik tritmɛnt program dɛm wae dɛn mek fɔ di wan dɛm wae gɛt Pakinsin kin mek dɛn balans, waka, ɛn stebul.
- Ɛksesaiz: I rili impɔtant fɔ du at le 150 minit ɛksesaiz fɔ yu at ɛn blɔd insay di wik. Dɛn dɔn si se tin dɛn lɛk fɔ rayd baysikul ɛn bɔksin kin rili bɛnifit wi.
- Mental Wɛlbɔdi: Fɔ liv wit wan sik wae nɔr de dɔn lɛk Pakinsin kin tranga fɔ yu maynd. So if yu de fil bad ɔr de wɔri, nɔr shem fɔ tɔk to pɔrsin wae sabi bɔt mɛntɛl hεlth, lɛk pɔrsin wae de stɔdi bɔt pɔrsin in maynd.
Ustɛm a fɔ go to di dɔktɔ bak?
We yu de tek di mɛrɛsin fɔ Pakinson, i impɔtant fɔ go to yu dɔktɔ ɔltɛm fɔ chɛk if di mɛrɛsin de wok ɛn if yu gɛt ɛni nyu sayn. Mek shɔ se yu tɔk to yu dɔktɔ, mɔ we tin dɛn lɛk dis.
- If yu gɛt sayd ɛfɛkt dɛn we yu nɔ go ebul fɔ bia wit.
- If yu sik nɔr de bɛtɛ ɔr de wɔs.
- If yu fil fɔ stɔp di mɛrɛsin.
Mɛsej we dɛn kin kɛr go na os
- Pan ɔl we dɛn nɔ kin ebul fɔ mɛn di sik we dɛn kɔl Pakinsin kpatakpata, dɛn kin kɔntrol di sayn dɛm fayn fayn wan ɛn yu kin liv fayn layf.
- Levodopa na di men ɛn di bɛst mɛrɛsin fɔ dis sik.
- Nɔ stɔp fɔ tek mɛrɛsin ɔ chenj di doz fɔ ɛni rizin if yu dɔktɔ nɔ advays yu.
- Ɛksesaiz ɛn fyzikal tritmɛnt impɔtant jɔs lɛk aw fɔ tek mɛrɛsin. Ɛksesaiz kin ɛp fɔ kɔntrol aw di sik de go bifo.
- If yu gɛt sayd ɛfɛkt ɔ ɔda prɔblɛm, nɔ fred fɔ tɔk to yu dɔktɔ. I rɛdi ɔltɛm fɔ ɛp yu.
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