Yu leg dɛn dɔn swel ɛn yu skin de fil rɔf? Lɛ wi lan bɔt dis (Pretibial Myxedema)!

Yu dɔn ɛva notis se di skin na yu leg, mɔ we de dɔŋ yu ni, kin swel wantɛm wantɛm, tik, ɛn sɔntɛnde i kin chenj in kɔlɔ? Ɔ i tan lɛk ɔrɛnj peel na sɔm say dɛn? If yu gɛt dɛn sik ya, yu kin gɛt wan sik we dɛn kɔl Pretibial Myxedema, we wi go tɔk bɔt tide.

Wetin na dis (Pretibial Myxedema)? Lɛ wi ɔndastand am simpul wan!

Fɔ tɔk am simpul wan, Pretibial Myxedema, we sɔm pipul dɛn kin kɔl Graves’ Dermopathy, na wan kayn Graves’ Disease, we na wan sik we kin afɛkt wi skin. i de kכz fכ di kכlכshכn fכ di kכbaidret εn shuga, כ mכr prεsis, glycosaminoglycans כ mucopolysaccharides, insay di dip layεr dεm na wi skin. Dɛn wan ya kin gɛda mɔ na di lכw leg dεm, dכn di kכn dεm. dis na we di leg dεm de swεla, di skin de kכmכt, εn di skin de skel (scaling plaques). Wetin di wɔd dɛn "Pretibial" ɛn "Myxedema" min?

• "Pretibial": dis de tכk bכt di big bon we de na di sayd fכ wi leg dכn di kכn, di fכnt pan di `(tibia)`. If wi se am na Sinhala, i tan lɛk "in front of the shinbone".
• "Myxedema": Dis min se di tisu dεm we de כnda wi skin de swel.

Udat dis tin kin afɛkt mɔ?

(Pretibial Myxedema) Pan ɔl we ɛnibɔdi kin gɛt am, sɔm pipul dɛn kin gɛt am mɔ. Dɛn na:

• Pipul wae gɛt Grev sik: Dis na di men tin wae de mɔna pipul dɛm.
• Pipul dεm wae gεt tayroyd prכblεm: Dis min kכndyushכn lεk `(Hypothyroidism)` (lכw tayroyd כ mon ) כ `( Hyperthyroidism )` (high thyroid hormone ).
• Pipul wae gɛt siriɔs ay sik: Dis kin gɛt fɔ du bak wit Graves’ Disease.
• Pipul dɛn we ol bitwin 40 ɛn 60 ia.
• Uman dɛm: Dis sik kin bɔku pan uman dɛm pas man dɛm.

Imajin, yu neba, Anti Susila, dɔn gɛt tayroyd prɔblɛm fɔ sɔm tɛm. Wantɛm wantɛm, i notis se di say we de dɔŋ di ni dɛn na in leg dɛn dɔn swel, di skin dɔn rɛd smɔl, ɛn i kin tan lɛk smɔl smɔl bɔmp dɛn we dɛn tɔch am. Fɔs, i bin tink se sɔntɛm na bikɔs i de tray tranga wan. Bɔt na we i sho am to dɔktɔ nɔmɔ i kam fɔ no se i kin bi Pretibial Myxedema.

Wetin na di men kayn Pretibial Myxedema?

Fo men kayn dis sik de. Di sayn dɛm kin difrɛn smɔl akɔdin to: 1. Difyuz: Dis na di kayn we we dɛn kin gɛt mɔ. dis kin bi se di εdima we nכ de pit we nכ de bulge we dεn prεs di skin pan di skin. 2. Plɛk: .Apat frɔm di swɛlin, tik tik, rayz, krɔst plek dɛn de na di skin. 3. Nodular: Apat frɔm di swɛlin, had nodul dɛn de ɔnda di skin. 4. Ɛlifantiasis: Dis na di kayn we we nɔ kin bɔku. insay dis kayn we, di limfatik wata kin gɛda ɔnda di skin, we kin mek di skin tan lɛk wɔt, rɔf.

Wetin na di sayn dɛm fɔ (Pretibial Myxedema)? Lɛ wi kam fɔ no dɛn gud gud wan!

If yu gɛt dis sik, yu kin gɛt wan ɔr mɔr pan dɛn sik ya:

• Swel: Di skin na yu leg kin luk big ɛn puf pas di de bifo.
• Had lumps ɔnda di skin: Yu kin fil dis we yu tɔch am wit yu an.
• Sɔm say dɛn na di skin kin tik ɛn kin tan lɛk plek: lɛk fish skel.
• Di skin ɛn di ia fɔlikul dɛn kin gɛt shayn, waks: I kin tan lɛk ɔrɛnj pil .
• Di kɔlɔ we di skin gɛt kin chenj: i kin kɔmɔt frɔm yɔlɔ ɛn ɔrɛnj to brawn, rɛd, ɛn pepul.
• Di swet kin bɔku ɔ di ia kin gro pasmak na di say dɛn we di sik afɛkt.
• Di skin kin at ɔ i kin it.

Fɔs, di sik kin bigin lɛk wan had lump na di skin. Dis lump kin gro big as tɛm de go, ɔ i kin jɔyn wit ɔda lumps.

Usay na di bɔdi dɛn sik ya kin afɛkt mɔ?

Di sayn dɛm wae kin kam wit Pretibial Myxedema na:

• Na di leg dɛn we de dɔŋ di ni dɛn.
• Na di fut dɛn we de na di fut.
• Di shin dɛn we de na di shin eria.

Sɔntɛnde, yu fes kin chenj bikɔs ɔf Graves’ Disease ɔr tayroyd kɔndishɔn, bɔt dat na difrɛn tin.

Wetin mek wi kin gɛt (Pretibial Myxedema)? Wetin na di tin dɛn we kin mek i apin?

Pan ɔl we dɛn nɔ dɔn ɔndastand gud gud wan yet wetin mek dis apin, bɔku tin dɛn dɔn kɔmɔt frɔm di risach. di men rizin fכ dis na di akyumyuleshכn fכ di shuga kכmpawnd dεm `(glycosaminoglycans כ mucopolysaccharides)` we wi bin mεnshכn fכs insay di `(dermis)` εn `(hypodermis)` layεr dεm na di skin. Bɔt wetin mek i kin gɛda da we de? 1. wan imyun sistεm prכsεs `(Autoimmune response)`: fכ simpul wan, wi bכdi in כwn difεns sistεm de stat fכ wok agens wi. insay dis, wi difεns sistεm de signal wi sεl dεm fכ prodyuz `(antibodi)` εgεst di tayroyd כmon dεm. dis `(antibodi)` de mek di sεl dεm prodyuz wan sכbstans we dεn kכl `(glycosaminoglycans)` we pasmak. 2. aktibכshכn fכ (T limfosayt) sεl dεm: `(T limfosayt)` na spεshal tכp sεl na wi imyun sistεm. dis sεl dεm de go insay di skin tisu εn de rilis mεsenja protin dεm we dεn kכl `(saytokin)`. dis saytokכn dεm de mek di sεl dεm prodyuz pasmak glycosaminoglycans. 3. Injuri rispɔns:Imajin se yu gɛt injuri na yu lכw leg, na di prεtibial εria. If yu gɛt haypothayrɔydism, di imyun sɛl ɛn protin dɛn kin gɛda na di say we di injury de. dis na biכs di tayroyd כmon dεm de kכntro di akyumyuleshכn fכ dεn kכmpawnd dεm ya na di tisu dεm. We ɔmon dɛn nɔ de, da kɔntrol de nɔ de igen.

Aw dɔktɔ kin no se i gɛt Pretibial Myxedema?

We yu go to dɔktɔ, i go aks yu fɔs bɔt yu sik ɛn ɛni ɔda mɛrɛsin we yu go gɛt (`(medical history)`). Dɔn dɛn go ɛgzamin yu (`(physical exam)`). Fɔ no if dis na (Pretibial Myxedema), dɔktɔ kin du dɛn tɛst ya:

• Blɔd tɛst: Chɛk yu tayroyd ɔmon lɛvɛl.
• Skin biopsy: dεn kin yuz dis fכ no if di kכndyushכn de εn fכ mכsu di lεvεl dεm fכ di glycosaminoglycans na di skin.

Yu tink se tritmɛnt de fɔ dis? Wetin dɛn kin du?

Bɔrku tɛm, di sayn dɛm fɔ Pretibial Myxedema na fɔ kɔsmɛtik nɔmɔ, so nɔr kin nid tritmɛnt ɔltɛm. Dat min se, bɔku tɛm dɛn nɔ kin kɔz ɛni big bad bad tin . Bɔt if yu nɔr kin fil fayn fɔ si ɔr yu gɛt ɔda sayn dɛm (it, pen), tritmɛnt dɛn de.

• We yu wɛr kɔmpreshɔn sɔks ɔ stɔkin: Dis kin mek yu nɔ swel.
• Krim ɔ ɔntmɛnt we yu kin put pan yu bɔdi: Nɔ it ɛn swel.
• Mεdikeshכn dεm εn injεkshכn dεm we dεn kin tek bay mכt εn we dεn kin put pan di skin: Fכ ridyus di lumps dεm כnda di skin כ fכ sכm chenj dεm na di we aw i de luk.
• Fɔ Trit Grev in Sik ɔ Tayrɔyd Kɔndishɔn: Dis na di tin we impɔtant pas ɔl . We dɛn trit di ɔndalayn kɔz, di sayn dɛm fɔ Pretibial Myxedema kin bɛtɛ bɔku tɛm.
• Plasmapheresis: Dis na tritmɛnt we kɔmplikt smɔl. I min se dɛn kin pul di wata we de na di blɔd (plasma), put di rɛd ɛn wayt blɔd sɛl dɛn ɛn di pletlɛt dɛn insay nyu sɔlvushɔn, dɔn dɛn put dɛn bak insay di bɔdi. Dis nɔto sɔntin we ɔlman go ebul fɔ du.

Impɔtant: Pan ɔl we ɔpreshɔn kin pul di nodul dɛn we de ɔnda di bɔdi, dɛn nɔ kin advays fɔ pul am. dis na biכs, as di skin de hεl afta dεn כpεrayshכn, di nodul dεm kin kam bak na di say we di injuri de. dis na biכs di bכdi de trit di say we dεn de du di כpεrayshכn lεk "wund."

Wetin na di mɛrɛsin dɛm we dɛn kin gi fɔ Pretibial Myxedema?

Yu dɔktɔ kin gi yu mɛrɛsin lɛk dis fɔ ɛp fɔ ridyus di sayn dɛm fɔ dis sik:

• (Kɔtikosterɔyd): .Dis na mɛrɛsin dɛn we dɛn kin put pan pɔsin in bɔdi we kin ɛp fɔ ridyus di swɛlin, inflamɛns, ɛn it.
• (Pentoxifylline): Dis na mɛrɛsin we dɛn kin tek bay mɔt ɛn we kin mek di blɔd go fayn fayn wan na di leg dɛn.
• (Octreotide): Dis na injɛkshɔn. I kin ridyus di sayz fɔ di lumps ɔnda di skin.
• (Rituximab): Dis na infyushɔn bak we dɛn kin put insay di bɛlɛ. I de ɛp wi bɔdi in antibodi dɛm fɔ wok fayn fayn wan.
• Intravenous immunoglobulin (IVIG): Dis na drɔg bak we dɛn kin gi insay wan vein. i de mek di antibodi dεm we de na di imyun sistεm wok fayn fayn wan.

Bifo yu bigin fɔ tek nyu mɛrɛsin, mek shɔ se yu tɔk to yu dɔktɔ bɔt di bad tin dɛn we i kin du, aw lɔng yu fɔ tek am, ɛn if i go mek yu gɛt prɔblɛm wit ɔda mɛrɛsin dɛn we yu de tek naw.

Aw kwik a go wɛl afta dɛn dɔn trit mi?

Di lɔng tɛm we yu go gɛt di sayn dɛm fɔ Pretibial Myxedema go difrɛn difrɛn wan fɔ di kayn sik we yu gɛt. If yu gɛt tritmɛnt, di sik kin bɛtɛ insay sɔm wiks to sɔm mɔnt. If dɛn nɔ gɛt tritmɛnt, sɔntɛnde i kin tek sɔm ia fɔ mek di sik dɔn fɔ insɛf. Bɔt mɛmba se if yu gɛt injury na yu leg dɛn we de dɔŋ, di sik kin kam bak.

Yu tink se we dɛn de fɔ mek dis (Pretibial Myxedema) nɔ apin?

No we nɔr de fɔ mek dis nɔr apin kpatakpata, bɔt yu kin du dɛn tin ya fɔ ridyus yu risk:

• Nɔ yuz tin dɛn we dɛn mek wit tabak.
• If yu gɛt tin dɛn we de afɛkt yu tayroyd wok, mek dɛn trit dɛn fayn fayn wan.
• Wear kɔmpreshɔn sɔks ɔ stɔkin na yu leg.

Wetin fɔ du if misɛf gɛt dis sik? Na sɔntin we wi fɔ fred?

Di prɔgnosis fɔ pipul dɛm wae gɛt Pretibial Myxedema kin jɔs fayn. If di sayn dɛm wae yu kin gɛt kin afɛkt aw yu luk, yu nɔr kin nid tritmɛnt. If yu gɛt mild kes, i go ɔltɛm go fɔ insɛf. If yu kes tranga pasmak, de prɔgnosis fayn, bɔt i kin tek sɔm ia fɔ mek i wɛl.

A nid fɔ go to dɔktɔ?

Pretibial Myxedema kin kam bak ivin afta i dɔn wɛl, mɔ if yu gɛt injuri na yu lɔwa leg. So, if yu sik dɔn stɔp ɛn afta dat i kam bak, tɔk to yu dɔktɔ. Dɔn bak, if yu de fil pen ɔ yu de it bad bad wan, mek shɔ se yu go to dɔktɔ.

Us kwɛstyɔn dɛn a fɔ aks di dɔktɔ?

I fayn fɔ mek yu gɛt sɔm kwɛstyɔn dɛn lɛk dis we yu rɛdi we yu go to dɔktɔ:

• A kin yuz kɔmpreshɔn sɔks fɔ ɛp wit Pretibial Myxedema?
• A nid tritmɛnt fɔ Pretibial Myxedema?
• Yu tink se na wan ɔndalayn tayroyd kɔndishɔn de mek a gɛt di sik?
• Aw a go tek kia ɔf mi skin we Pretibial Myxedema dɔn afɛkt?

Wetin na di difrɛns bitwin (Pretibial Myxedema) ɛn (Erythema Nodosum)?

Dɛn tu tin ya kin afɛkt wi skin, mɔ di skin na wi leg dɛn we de dɔŋ di ni. Bɔt difrɛns de pan de sayn dɛm:

• (Pretibial Myxedema): Dis kin mek yu swel ɛn gɛt plek dɛn we de shayn, we tik, we tan lɛk kɔral.
• (Erythema Nodosum): Dis kin mek yu skin swel ɛn smɔl smɔl bɔmp dɛn we de mek yu fil pen.

Fɔ dɔn, tin dɛn we wi fɔ mɛmba

Pretibial Myxedema na wan sik wae nɔr kin nid tritmɛnt. Bɔku tɛm, i kin go fɔ insɛf. Bɔt if di chenj we yu de luk de mɔna yu, tritmɛnt dɛn de we yu kin gɛt. We yu wɛr kɔmpreshɔn sɔks, dat kin ɛp fɔ mek yu nɔ swel ɛn mek yu fil fayn. If yu gɛt pen ɔ yu de it bad bad wan na yu leg dɛn we de dɔŋ, mek shɔ se yu tɔk to dɔktɔ. Dɔn bak, dis sik kin gɛt fɔ du wit Graves’ Disease ɛn tayroyd prɔblɛm, so i impɔtant fɔ no bɔt dɛn wan ya bak.

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