Yu gɛt gaut ? Ɔ pɔsin we yu sabi gɛt dis sik? Dɔn yu go mɔs dɔn rili no bɔt da bad bad pen de na di jɔyn dɛn. So, wan pan di mɛrɛsin dɛm wae dɔktɔ dɛn kin kɔmand fɔ kɔntrol gaut fɔ lɔng tɛm na Probenecid. Insay dis atikul, wi go tɔk bɔt dis Probenecid pil, wetin kin apin wit am, ɛn us tin dɛn fɔ tek tɛm wit we yu de tek am.
Wetin kin rili apin wit dis Probenecid mɛrɛsin?
Fɔ tɔk am simpul wan, dis mɛrɛsin we dɛn kɔl Probenecid de wok bay we i de mek di yurik asid we pasmak kɔmɔt na wi bɔdi kwik kwik wan tru di urine. As yu no, gaut kin apin we di yurik asid we de na di bɔdi de bɔku ɛn i kin de na di jɔyn dɛn lɛk kristal. So, bay we dis mɛrɛsin de ridyus di lɛvɛl we yurik asid de, i kin mek di gaut atak we de mek yu fil pen nɔ kam bak .
Dis mɛrɛsin gɛt ɔda wok bak. I kin ɛp sɔm antibayɔtik dɛn lɛk penisilin fɔ de na di bɔdi fɔ lɔng tɛm, ɛn dis kin mek di antibayɔtik wok fayn.
Tin dɛn fɔ tɛl yu dɔktɔ bifo yu tek mɛrɛsin
Bifo yu bigin fɔ tek Probenecid, i rili impɔtant fɔ gi yu dɔktɔ kɔmplit diskripshɔn bɔt yu wɛlbɔdi kɔndishɔn. Mek shɔ se yu tɛl dɛn bɔt ɛni wan pan dɛn tin ya we yu gɛt:
- If yu gɛt akyu gauti atak naw: Dɛn kin yuz dis mɛrɛsin fɔ mek di pen nɔ kam, nɔto fɔ ridyus am we i dɔn ɔlrɛdi de. So, dɛn nɔ kin bigin am da tɛm de.
- If yu gɛt ɛni blɔd sik ɔ blɔd prɔblɛm .
- If yu gɛt kidni sik ɔ kidni ston : Bikɔs dis mɛrɛsin de wok tru di kidni, if yu gɛt ɛni kidni prɔblɛm, yu dɔktɔ fɔ no bɔt am.
- If yu jɔs dɔn gɛt redyushɔn tɛrapi.
- If yu gɛt ɔlsa na yu bɛlɛ .
- If yu gɛt alɛji fɔ probenecid, sɔlfa drɔgs, ɔ ɛni ɔda mɛrɛsin, it, ɔ day.
- If yu gɛt bɛlɛ ɔ yu de tray fɔ gɛt bɛlɛ.
- If yu na mama we de gi pikin in bɛlɛ.
Bay dis infɔmeshɔn, yu dɔktɔ go disayd if dis mɛrɛsin fayn fɔ yu ɔ if dɛn nid fɔ chenj di doz.
Aw ɛksaktɔli yu kin yuz dis mɛrɛsin?
Di we aw fɔ yuz dis rili simpul, bɔt i rili impɔtant.
- Dis pil wit big glas wataDrink. I rili impɔtant bak fɔ drink bɔku wata ɔl di de.
- Tek di rayt doz, jɔs lɛk aw yu dɔktɔ tɛl yu. Tek yu mɛrɛsin di tɛm we dɛn dɔn sɛtul, ɛn nɔ skip ɛni apɔntinmɛnt.
- Nɔ stɔp fɔ tek di mɛrɛsin te yu dɔktɔ tɛl yu fɔ tek am. Kɔntinyu fɔ tek am ilɛksɛf yu fil fayn.
- If dɛn gi am to pikin dɛn: Dɛn nɔ kin gi dis mɛrɛsin to pikin dɛn we nɔ rich 2 ia yet. If yu de gi am to pikin dɛn we dɔn ol pas dat, tɔk to dɔktɔ we de mɛn pikin dɛn bɔt am ɛn fala wetin i tɛl yu fɔ du.
- Ɔvados: If yu tink se yu dɔn tek mɔ pas di doz we dɛn tɛl yu fɔ tek, kɔl di Nashɔnal Pɔyzin Infɔmeshɔn Sɛnta wantɛm wantɛm na di Kɔlɔmbɔ Nashɔnal Ospital . Ɔ go na di Imejɛnsi Tritmɛnt Yunit (ETU) na di ɔspitul we de nia yu.
Dis mɛrɛsin na fɔ yu nɔmɔ. Nɔ gi am to ɔda pɔsin we gɛt di sem sayn lɛk yu. Di rayt mɛrɛsin fɔ ɛnibɔdi kin difrɛn.
Ɔda mɛrɛsin dɛm wae kin miks wit dis mɛrɛsin
Probenecid kin intarakt wit ɔda mɛrɛsin dɛn. So tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek, ivin di vaytamɛn dɛn. Di tebul we de dɔŋ ya go ɛksplen dis klia wan.
| Posisibul intarakshɔn wit Probenecid | |
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| Mɛrɛsin dɛn we dɛn nɔ fɔ ɛva tek togɛda | |
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| Mɛrɛsin dɛn we dɛn fɔ tek tɛm yuz ɛn ripɔt to di dɔktɔ | |
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Dis list nɔ kɔmplit. So tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek, if yu de smok, ɔ if yu de drink rɔm.
Speshal tin dɛm we yu nid fɔ no bɔt we yu de tek Probenecid
- I kin tek tɛm fɔ si di rizɔlt: I kin tek sɔm mɔnt fɔ si di ful ifɛkt we dis mɛrɛsin gɛt. So, ilɛksɛf yu gɛt gaut pen ɔ yu nɔ gɛt pen, kɔntinyu fɔ tek di mɛrɛsin fɔ lɔng tɛm we yu dɔktɔ tɛl yu fɔ tek am. If yu gɛt pen wantɛm wantɛm, yu dɔktɔ go gi yu wan ɔda mɛrɛsin fɔ dat.
- Tek tɛm wit mɛrɛsin dɛn we de mek yu fil pen:
- Nɔ rɔm: Rɔm kin ambɔg di wok we dis mɛrɛsin de du. So, nɔ drink rɔm.
- Drink bɔku wata: I rili impɔtant fɔ drink at le 8-10 glas wata wan de fɔ ɛp fɔ pul yurik asid kɔmɔt na di bɔdi ɛn fɔ mek yu nɔ gɛt ston na yu kidni. Nɔ mek yu nɔ gɛt wata na yu bɔdi.
- I kin afɛkt sɔm tɛst dɛn: Dis mɛrɛsin kin afɛkt di rizɔlt fɔ sɔm tɛst dɛn we kin chɛk fɔ si if shuga de na di urine. If yu de du dis kayn tɛst, tɛl yu dɔktɔ bifo tɛm.
- Skin iritashɔn, it, ayv (Alɛji riakshɔn) .
- We yu fes, yu lip, ɔ yu tɔng swel
- I nɔ kin izi fɔ yu fɔ blo
- Fiva, kol, sayn dɛm fɔ infekshɔn
- Blɔd we de na di urine
- Pen na di bɛlɛ we de dɔŋ ɔ di flank (we gɛt fɔ du wit di kidni) .
- Pen ɔ i nɔ izi fɔ pis
- Joint de swel ɛn pen
- Blɔd ɔ brus we nɔ kɔmɔn
- Taya ɔ taya we nɔ kɔmɔn
- Diziz we pɔsin kin gɛt
- Fɔ mek yu flash
- Fɔ pis bɔku tɛm
- Di ia we de lɔs
- Ed de at
- Fil fɔ it
- Nɔs, fɔ vɔmit
- Pen na di gɔm
- Probenecid na mɛrɛsin we dɛn kin yuz fɔ kɔntrol gaut fɔ lɔng tɛm, nɔto fɔ atak we pɔsin kin gɛt wantɛm wantɛm.
- We yu de tek dis mɛrɛsin, i rili impɔtant fɔ drink bɔku wata ɔl di de.
- Nɔ tek aspirin ɔ ɔda mɛrɛsin dɛn we de mek yu fil pen (espɛshali NSAID) we yu nɔ go to yu dɔktɔ.
- Gi yu dɔktɔ kɔmplit diskripshɔn bɔt ɔl di ɔda mɛrɛsin dɛn, vaytamɛn dɛn, ɛn sɔpɔtmɛnt dɛn we yu de tek.
- If yu gɛt ɛni bad bad sayd ɛfɛkt (e.g. skin rɔsh, i nɔ izi fɔ blo, bad bad pen), go to dɔktɔ wantɛm wantɛm.
NSAID pen kil dɛm lɛk aspirin ɛn ibuprofen kin ridyus di wok we dis mɛrɛsin de du. So, nɔ tek mɛrɛsin fɔ mɛn pen we yu nɔ de bay fɔ ed we de at ɔ ɔda pen. Aks yu dɔktɔ bifo yu tek ɛni mɛrɛsin fɔ mek yu fil pen.
Wetin na di bad tin dɛn we kin apin to pɔsin?
Lɛk ɛni mɛrɛsin, Probenecid kin mek sɔm pipul dɛn gɛt sayd ɛfɛkt. Sɔm pan dɛn tin ya siriɔs, ɛn ɔda wan dɛn nɔ kin at fɔ du.
| Siriɔs sayd ɛfɛkt dɛm we yu fɔ ripɔt to yu dɔktɔ wantɛm wantɛm | |
|---|---|
| Sayd ɛfɛkt dɛn we nɔ kin siriɔs, bɔt dɛn fɔ ripɔt to di dɔktɔ if dɛn kɔntinyu fɔ de | |
Mɛsej we dɛn kin kɛr go na os
👩🏽 ⚕️ Ɔda kwɛstyɔn dɛn (FAQ dɛn)
💬 Wetin dɛn kin yuz Probenecid tablɛt fɔ?
Dis na wan mɛrɛsin we rili wok ɛn pawaful fɔ di bad bad at sik we dɛn kɔl ‘Gout’ (Uricosuric agent)! Di wan dɛn we gɛt gaut kin sɔfa wit pen ɛn swel we dɛn nɔ kin ebul fɔ bia bikɔs ɔf di ‘Uric Acid’ kristal dɛn we kin stik lɛk nidul insay di jɔyn dɛn. Wetin dis pil de du na fɔ swip ɔl da denja yurik asid de na di bɔdi ɛn flush am kɔmɔt.
💬 We dis mεdisin (Probenecid) go insay di bכdi, aw i de pul di 'uric acid' we de mek gכt pen?
nכmal wan, afta wi bכdi dכn kכl yurik asid tru di kidni dεm insay di urine, di kidni dεm de riabsכp sכm pan am bak insay di bכdi/bכdi (Reabsorption/URAT1). wetin dis pil (Probenecid) de du na 100% blok dat ‘riabsorption factory’. Bikɔs i nɔ kin ebul fɔ tek am, ɔl di yurik asid we de na yu blɔd kin kɔmɔt na yu bɔdi lɛk riva (Excretion) we nɔ gɛt ɛnitin fɔ ambɔg am.
💬 Wetin mek yu nid fɔ drink bɔku wata we yu de tek dɛn pils ya? Wetin na di prɔblɛm dɛn we kin apin?
dis pil de push כl di yurik asid na di bכdi insay di kidni/urine, so if yu nכ drink '2-3 lita wata wan de', da yurik asid de go kכmכt na di kidni dεm εn fכm ‘ston (Uric acid kidney stones)’. Dat kin kil pɔsin! Di ɔda spɛshal tin na dat if yu tek wan antibayɔtik we de kil baktri dɛm (lɛk Penicillin) we yu de tek dis pil, dis kin mek di amɔnt fɔ da antibayɔtik de we de na di bɔdi (to di say we i kin bi pɔyzin) ɛn mek di sayd ifɛkt dɛm we di mɛrɛsin gɛt (Drug interactions) bɔku.
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