Wetin na Spindle Cell Sarkoma? Lɛ wi tɔk bɔt am simpul wan!

Yu dɔn ɛva wɔri bɔt sɔntin we strenj, lɛk pen ɔ swel na yu bon ɔ say dɛn we saf lɛk yu mɔsul dɛn? Sɔntɛnde, dɛn tin ya kin bi nɔmal tin. Bɔt, nɔr kin bɔrku, dɛn sayn ya kin bi sayn fɔ sɔmtin wae siriɔs. So, tide wi go tɔk bɔt wan kayn kansa we nɔ kin bɔku, bɔt impɔtant fɔ no bɔt. Dɛn kɔl dat Spindle Cell Sarcoma.

Wetin rili na Spindle Cell Sarcoma?

Fɔ tɔk am simpul wan, Spindle Cell Sarcoma na wan kayn kansa we nɔ kin bɔku ɛn we kin kam na di bon ɛn sɔft tisu dɛn na wi bɔdi. yu no se ‘sarkoma’ de tכk bכt abnכmal sεl mas dεm, כ tכmכro dεm we de divεlכp na dεn bon dεm de εn di tisu dεm we kכnεkt to dεm?

naw, di spεshal tin fכ Spindle Cell Sarcoma na dat we yu luk dεn abnכmal sεl dεm כnda maykroskכp, dεn de lεk ‘spindle’. Spindle na shep lɛk kandul, di sayd dɛn tan ɛn di midul tik smɔl. Na dat mek i gɛt in nem.

Bikɔs ɔf di advans lab tɛst dɛn, dɔktɔ dɛn dɔn ebul fɔ no pas 75 kayn sarkoma. Spindle cell sarcoma na wan pan dɛn kayn sɔbtayp ya. infakt, dεn de yuz di tεm ‘spindle cell sarcoma’ fכ dεskrεb sarkoma dεm we dεn nכ kin kכl kכrekt wan bay sכm lab tεst dεm, lεk stεn כ jεnεtik kכntribyushכn. So, na smɔl brayt tɛm.

Usay dɛn tumbu ya kin apin mɔ?

Spindle Cell Sarcoma kin divεlכp bכku tεm na di lכng bon dεm na wi bכdi. Fɔ ɛgzampul:

• Yu shɔl bon (`femur`) .
• Shin bon (tibia) .
• Di bon we de ɔp di an (humerus) .

Bɔt, nɔto jɔs dɛn ples ya. Sɔm pipul dɛn kin gɛt spindl sɛl sarkoma na di bɛlɛ, ed ɛn nɛk, ɛn ɔda pat dɛn na di bɔdi.

Wetin na di men kayn Spindle Cell Sarcoma?

Naw, luk, ɔl di sarkoma dɛn kin bigin na sɔft tisu. Dat min se, insay tin dεm lεk fεt, mכsul, blɔd vesel, nεv, εn di tisu we de rawnd di bon dεm. Dɔktɔ dɛn kin klas di spindl sɛl sarkoma dɛn mɔ bay di kayn sɛl we di kansa bigin insay.

We dɔktɔ dɛn ɔndastand di kayn sɛl ɛn di kayn we aw i tan dis we, dɛn kin ebul fɔ no aw di kansa go ebul fɔ skata. Dis kin ɛp dɛn bak fɔ no di bɛst tritmɛnt dɛn.

pan ɔl we ‘spindle cell sarcoma’ na wan brayt wɔd, sɔm men kayn dɛn de:

• Pleomorphic Sarkoma we nɔ difrɛn: .as di nem sho, di sεl dεm na dis kayn kεnsar ‘undifferentiated’. Dis min se i nɔ klia us kayn sɛl di kansa bigin frɔm. di sik sεl dεm na di tכmכro na ‘pleomorphic’, we min se dεn de kam insay difrεn shep εn saiz dεm. In ɔda wɔd dɛn, tumbu na wan kɔlekɛshɔn fɔ sɛl dɛn frɔm difrɛn kayn dɛn.
• Fibrosarcoma: Dɛn tin ya kin kɔmɔt frɔm sɛl dɛn we dɛn kɔl fibroblast. di fibroblast dεm na di men bildin blכk dεm fכ di kכnektiv tisu dεm na wi bכdi.
• Leiomyosarcoma: Dɛn tin ya kin bigin na di smol mכsul sεl dεm. dis dεm difrεn frכm di sεl dεm na di skel mכsul tisu, we wi de yuz fכ muv wi bכdi εn gεt εnεji. Smol mכsul sεl dεm de na wi insay כgan dεm, di bכdi kכva dεm, εn sכm bon dεm lεk sכft tisu.

Aw dis sik kin kɔmɔn?

Lɛk ɔda kayn sarkoma, spindl sɛl sarkoma nɔ kin bɔku . infakt, i de mek lεs dan 10% pan כl di bon εn sכft tisu kεnsar dεm. Kip in maynd, e kin so rare dat yu dɔktɔ nɔr kin saspek dis kayn kansa fɔs. Yu kin gɛt fɔ go to bɔku dɔktɔ apɔntinmɛnt, to sɔm spɛshal dɔktɔ dɛn, ɛn du bɔku tɛst bifo yu gɛt diagnosis.

Spindle cell sarkoma kin kam pan ɛnibɔdi. Bɔt i kin apin mɔ pan pipul dɛn we dɔn pas 40. Pipul dɛn we gɛt di undifferentiated pleomorphic sarcoma we wi bin dɔn tɔk bɔt kin bi bitwin 60 ɛn 70 ia.

Wetin na di sayn dɛm fɔ dis?

Di sayn dɛm fɔ spindl sɛl sarkoma kin difrɛn. Dɛn kin dipen pan di saiz fɔ di tumbu, di nɔmba fɔ di tumbu dɛn, ɛn us bon (ɔ ɔda pat dɛn na di bɔdi) di kansa sɛl dɛn de insay.Na sɔm sayn dɛn we yu fɔ tek tɛm wit mɔ :

• Bon pen: Dis pen kin de ɔltɛm ɔr kin kam ɛn go. I kin fil lɛk se sɔmbɔdi de chuk yu frɔm insay.
• Bɔn we brok na say we kansa wik: Dɛn kɔl dis ‘pathological fracture.’ Bɔn kin brok ivin if i fɔdɔm smɔl.
• Tɛnd ɔ swel we yu prɛs di say we di tumbu de: I kin ivin gɛt tumbu we big fɔ ol na di an.
• Nɔ ebul fɔ muv wan jɔyn nia di tɔŋ fayn fayn wan: Imajin if di ni de nia, i go at fɔ bɛn ɔ ɛkstɛnd di ni.
• Taya: Dis nɔto jɔs nɔmal taya. Na taya pasmak wae nɔr de go ilɛksɛf yu slip ɔr rɛst.
• Malaise: Fɔ fil nɔr wɛl , witout ɛni rizin, lɛk se pɔrsin nɔr gɛt trɛnk ɔr intres pan ɛnitin.

Wetin kin mek pɔsin gɛt spindle cell sarkoma?

Lεk כl כda kεnsar dεm, spindl sεl sarkoma kin bigin we hεlty sεl dεm kin bi malignant. Dɛn bad bad sɛl dɛn ya kin gro we dɛn nɔ ebul fɔ kɔntrol dɛnsɛf, ɛn dɛn kin mek tɔŋ dɛn. dis tכmכro dεm kin pwεl di hεlty tisu dεm we de rawnd. Di tin we denja pas ɔl na dat dɛn kansa sɛl ya kin kɔmɔt nia di fɔs tɔŋ ɛn skata ɔlsay na di bɔdi, ɛn pwɛl ɔda tisu ɛn ɔgan dɛn. Dis na wetin wi kin kɔl mɛtastas, ɔ mɛtastas kansa.

Bɔt, na sɔntin we wi fɔ no. nכmal wan, spindl sεl dεm (we dεn gro fayn fayn wan) na rili gud tin. di spindl sεl dεm de fכm usay di tisu dεn dכn pwεl. So, fɔ gɛt spindl sɛl na sayn fɔ se yu wund de wɛl. Dɛn sɛl dɛn ya kin dɔn we di wund wɛl.

כltu, insay spindl sεl sarkoma, dεn spindl sεl dεm ya de kכntinyu fכ gro εn bכku. Sayɛnsman dɛn nɔ dɔn fɛn wan patikyula rizin yet we mek dɛn sɛl dɛn ya kin bi bad bad wan.

Bɔt sɔm pipul dɛn we de stɔdi bɔt dis dɔn kam fɔ no se sɔm tin dɛn we pɔsin kin chenj in jɛnɛtiks kin mek i gɛt dis kansa mɔ ɛn mɔ. ‘Myutashכn’ na mistek we de insay wi jin dεm, di sistεm we de tεl wi sεl dεm aw fכ wok. pan di kes fכ spindl sεl sarkoma, dεn mכtεshכn ya kin bi frכm frכm sεl, we min se dεn kin rכn insay famili.

Wetin na di tin dɛm wae kin mek pɔrsin gɛt dis kansa?

difrεn tin dεm de we kin mek di risk fכ gεt spindl sεl sarkoma bכku. Lɛ wi tek wan luk pan wetin dɛn bi:

• Bone Infarction: Dis na we di bon tisu de day bikɔs i nɔ de gɛt inof blɔd. As yu no, di bon tisu nid blɔd fɔ liv, ɛn na dat ɔksijɛn de du.
• Fibrous Dysplasia: Insay dis kכndishכn, di hεlty bon tisu dεm de riples di fibrous bon lεk tisu. dis de mek di risk fכ fraktכs εn (rili rεli) kin mek di divεlכpmεnt fכ fibrosarkoma.
• Osteomyelitis: Dis na infεkshכn we de afekt di spכnj tisu insay sכm bon dεm, we dεn kכl bon mכro. Dis kin apin if baktri ɔ ɔda jem dɛn kɔmɔt na yu blɔd to di bon ɛn infɛkt di sɛl dɛn we de de.
• Paget in sik na di bon: Dis na wan sik wae de kam fɔ lɔng tɛm (we nɔr de mɛn). I kin mek di bon dɛn wik ɛn i kin brok izi wan. dis kin mek di risk fכ gεt bon kεnsar, inklud spindl sεl sarkoma.
• Fɔ dɔn gɛt redyushɔn tɛrapi fɔ kansa:Radieshɔn tɛrapi de yuz ay ɛnaji rayt (bɔku tɛm na ay ɛnaji ɛkstrem rayt) fɔ pwɛl di kansa sɛl dɛn. Na sכm tεm, spindl sεl sarkoma dεn dכn divεlכp na εria dεm we dεn trit wit rεdyushכn. We dis kin apin, di sarkoma kin kam fɔ sɔm ia afta dɛn dɔn trit am (sɛvin to twɛnti ia). Bɔt mɛmba se, nɔr to 1% pan di pipul dɛm wae de gɛt redyushɔn tɛrapi kin gɛt dis kayn kansa wae gɛt fɔ du wit redyushɔn.

Wetin na di kɔmplikɛshɔn dɛm we de kam wit spindl sɛl sarkoma?

Dis kansa de mek yu bon dεm brok (fracture) na di say we di tכmכro de. We bon brok, di kansa sɛl dɛn we kɔmɔt na di tumbu kin travul go na di say dɛn we de nia de.

Bɔt stil, pipul dɛn stil de agyu bɔt if dis kayn bon we de brok de mek difrɛns to di ɔl di prɔgnosis (dat na di tin we go apin) fɔ di kansa, ɔ if di tin we go apin na fɔ jɔs gɛt fɔ du wit di kansa we de fa fawe (mɛtastatik spred).

Aw dɛn kin no se pɔsin gɛt spindl sɛl sarkoma?

Bifo yu dɔktɔ no ɛn stej yu kansa, i go mɔs bi se dɛn go du bɔku tɛst ɛn tin dɛn fɔ du. We di kansa stej de mek dɔktɔ dɛn ebul fɔ no aw di kansa siriɔs bay di sayz we di tumbu de, usay i de, ɛn if i dɔn skata. we dεn de stej bon kεnsar, dεn de luk bak if di tכmכro na ‘hay-grεd’ כ ‘lכw-grεd’. di hכy grεd tכmכro dεm gεt m כr abnכmal -luk sεl dεm. Dɛn kin gro ɛn skata kwik kwik wan.

כl di spindl sεl sarkoma dεm na hכy grεd.

Test dɛn fɔ tek imej

Pan ɔl we di tɛst we dɛn kin yuz fɔ mek pikchɔ nɔ kin no di kayn kansa, dɛn kin sho di sayz ɛn di say we di tumbu de. Dɛn kin sho bak if di kansa dɔn spre pas di praymari tumbu.

• X-ray: X-ray kin sho tumor ɔ ɔda tin dɛn we nɔ fayn na yu bon dɛn. We yu tek ɛkstrem rayt na yu chɛst, yu go si if di kansa dɔn skata to di lɔng dɛn. bכku tεm di mεtastas spindl sεl sarkoma kin spre to di lכng fכs.
• MRI Scan: MRI de yuz big magnet, redio wev, ɛn kɔmpyuta fɔ tek pikchɔ fɔ tin dɛn we de insay di bɔdi. Nɔ lɛk X-ray, MRI kin sho sɔft tisu bɔku bɔku wan. Dis kin fayn mɔ fɔ dɔktɔ dɛn fɔ no di sɔft tisu dɛn we dɛn tink se na sarkoma.
• CT Skan: CT skan de yuz X-ray ɛn kɔmpyuta fɔ mek tri-dimɛnshɔnal (3D) pikchɔ dɛn bɔt bon ɛn sɔft tisu dɛn. insay di kes fכ spindl sεl sarkoma, CT skan kin sho if di kεnsar dכn spre to sכft tisu dεm. Dɛn kin bɛtɛ bak fɔ fɛn fraktrɔs ɔ say dɛn we di bon dɛn wik.
• PET Skan: PET skan de yuz wan tin we dɛn kɔl traysa fɔ fɛn kansa sɛl dɛn ɔlsay na di bɔdi. Dɛn kin ɛp fɔ fɛn mɛtastasayz spindl sɛl sarkoma. Yu kin gɛt PET skan bak fɔ si aw yu tritmɛnt de wok. Bɔt dɛn nɔ kin yuz PET skan fɔ ɔl kayn sarkoma. Yu dɔktɔ go disayd if PET skan fayn fɔ yu.

Blɔd tɛst dɛn

No patikyula blɔd tɛst nɔ de we go ebul fɔ no spindle cell sarcoma. Bɔt blɔd tɛst de gi impɔtant tin dɛn bɔt yu wɛlbɔdi biznɛs, ɛn i impɔtant fɔ mek yu dɔktɔ no da infɔmeshɔn de. Jɛnɛral wan, blɔd tɛst kin gi infɔmeshɔn bɔt tin dɛn lɛk:

• Yu blɔd sɛl dɛn
• Di wok we di ɔgan dɛn de du
• di εnzym lεvεl dεm (εnzym dεm na kεmikכl dεm we de εp di כgan dεm fכ du imכtant prכsεs dεm) .

Bayopsi we dɛn kin du

Di bɛst we fɔ no fɔ tru if wan lump gɛt kansa na fɔ du bayɔpsi. Na di wangren we bak fɔ no di kayn kansa ɛn di gred we i gɛt. We dɛn de du bayɔpsi, dɔktɔ kin tek wan sampul pan di tisu frɔm di lump ɛn sɛn am na lab fɔ chɛk di sɛl dɛn.

Bɔrku pipul dɛm wae gɛt spindle cell sarcoma kin gɛt nidul bayɔpsi. Dɔktɔ dɛn kin numb di tisu we de rawnd di tumbu ɛn afta dat dɛn kin yuz wan smɔl nidul we gɛt ol fɔ tek wan sɛmpul. Fɔ ɛp di dɔktɔ fɔ no ustɛm na yu bɔdi fɔ put di nidul, yu kin nid bak fɔ tek ɛkstrem rayt ɔ CT skan.

Aw dɛn kin trit spindle cell sarkoma?

Di tritmɛnt we yu go gɛt go dipen pan yu wɛlbɔdi, di say we yu de, di sayz, di gred, ɛn ɔda tin dɛn. I dipen bak if yu de gɛt tritmɛnt fɔ di fɔs tɛm ɔ if di kansa dɔn kam bak afta tritmɛnt (we de kam bak).

Ɔpreshɔn

Di gol fɔ ɔpreshɔn na fɔ pul di tumbu we yu de kip bɔku pan yu bon as yu ebul. If dεn kin pul כl di trays dεm fכ kεnsar na di praymar tכmכro εn sεkכnd tכmכro dεm, dεn kin kכl di kεnsar. Bɔt we di kansa dɔn skata pas di fɔs tumbu, i kin at fɔ pul am kpatakpata.

Kimotɛrapi

Kimotɛrapi na tritmɛnt we de yuz drɔgs fɔ kil kansa sɛl dɛn ɔlsay na di bɔdi. Dɛn kin gi yu kemotɛrapi bifo dɛn du yu ɔpreshɔn fɔ mek di tumbu smɔl ɛn mek i izi fɔ pul am. Ɔ, dɛn kin gi yu kemotɛrapi fɔ kil ɛni kansa sɛl we lɛf afta dɛn dɔn du di ɔpreshɔn. Dɛn kin yuz kimotɛrapi bak as ‘palliative care’. Pan ɔl we i nɔ kin ebul fɔ mɛn kansa, kemotɛrapi kin kil di kansa sɛl dɛn fɔ ridyus di sayn dɛn lɛk bon pen.

Dɛn kin gi bɔku pipul dɛn wan kɔmbayn kemotɛrapi mɛrɛsin fɔ mek di tritmɛnt wok fayn. Dipen pan if yu de gɛt tritmɛnt fɔ di fɔs tɛm, nɔ de ansa fayn to sɔm pan di kemo drɔgs, ɔ if di kansa dɔn kam bak afta yu dɔn go insay ``rɛmishɔn,'' dɛn kin gi yu difrɛn kemo drɔgs. ``Rεmishכn'' min se di kansa dכn bεtε כ go kכmplit afta tritmεnt.

Rɛdieshɔn Tɛrapi

External Beam Radiation Therapy (EBRT) de yuz wan mashin fɔ dayrɛkt ɛkstrem rayt pan di tɔŋ fɔ kil di kansa sɛl dɛn. If yu nɔ ebul fɔ du ɔpreshɔn, dɛn kin gi yu raytin tɛrapi fɔ pwɛl di tumbu. Sɔntɛnde, dɔktɔ we de du ɔpreshɔn nɔ go ebul fɔ rich di tumbu we dɛn de du ɔpreshɔn pan am. I kin tu dip insay di tisu ɔ i kin tu nia di impɔtant ɔgan dɛn fɔ pul am sef wan. If na so i bi, dɛn kin gi yu redyushɔn tɛrapi insted.

Lɛk kemotɛrapi, redyushɔn tɛrapi kin ridyus di sik dɛn bak if dɛn nɔ ebul fɔ mɛn di kansa.

Wetin na de kɔmplikeshɔn ɔr sayd ɛfɛkt dɛm wae de tritmɛnt kin gɛt?

I kɔmɔn fɔ gɛt sayd ɛfɛkt frɔm kemotɛrapi ɛn redyushɔn tɛrapi we dɛn de trit kansa. Dɛn tin ya kin de fɔ sɔm tɛm afta di tritmɛnt dɔn. I impɔtant fɔ aks yu dɔktɔ bɔt di bad tin dɛn we kin apin to yu, i kin dipen pan di tritmɛnt we yu de gɛt.

Ustɛm a fɔ go to mi dɔktɔ?

Yu dɔktɔ go tɛl yu aw ɔltɛm yu nid fɔ kam insay fɔ tritmɛnt, ɔ fɔ du tɛst fɔ si if di kansa stil de na ``rɛmishɔn.`` Bɔrku pipul dɛm wae gɛt kansa wae de na rɛmishɔn go nid fɔ go to dɔktɔ mɔr tɛm na di fɔs stej. As yu de nɔ gɛt kansa fɔ lɔng tɛm, di nɔmba fɔ di fɔlɔp apɔntinmɛnt fɔ chɛk fɔ si if i kam bak go go dɔŋ.

Us kayn fɔlɔp tritmɛnt a nid?

Dipen pan ɔmɔs bon di dɔktɔ we de du di ɔpreshɔn bin gɛt fɔ pul, yu kin nid fɔ du ɔda tin dɛn. Dɛn tin ya kin ɛp fɔ mek di bon kɔntinyu fɔ wok. Fɔ ɛgzampul, yu kin nid fɔ mek dɛn kɔt yu bon. Bɔn graft min fɔ riples di tisu we dɛn pul wit tisu frɔm ɔda pat na yu bɔdi ɔ frɔm pɔsin we gi yu. Yu kin nid bak wan atifishal limb. Yu kin nid ɔda tritmɛnt fɔ ɛp yu fɔ ajɔst to dɛn chenj ya.

Us kwɛstyɔn dɛn a fɔ aks mi dɔktɔ bɔt spindle cell sarcoma?

Na sɔm impɔtant kwɛstyɔn dɛn we yu fɔ aks yu dɔktɔ:

• Usay di kansa de?
• Wetin na di stej/grɛd fɔ kansa?
• Aw da stej/grɛd de afɛkt mi tritmɛnt plan?
• Us tritmɛnt sayd ɛfɛkt dɛn a fɔ ɛkspɛkt?
• Yu tink se dɛn go ebul fɔ mɛn mi kansa?
• Wetin na di gol dɛm fɔ tritmɛnt?
• Yu kin kɔnɛkt mi to palliative care services fɔ ɛp mi fɔ bia wit mi kansa diagnosis?

Yu tink se dɛn kin mɛn spindle cell sarkoma? Aw i siriɔs?

If dɛn ebul fɔ pul ɔl di tin dɛn we de na di kansa, dɔktɔ dɛn kin mɛn di spindle cell sarcoma. Spindle cell sarcoma we nɔ dɔn spre pas di say we i bin de fɔs, i izi fɔ mɛn. Bɔt fɔ trit sarkoma we dɔn skata na tin we rili tranga . Metastatic Spindle Cell Sarkoma nɔ kin rili wɛl.

Dis kayn kansa kin bi ‘high-grade’. Dis min se i de gro kwik kwik wan ɛn i de skata kwik kwik wan. Afta i dɔn rɛmishɔn, i kin izi fɔ kam bak, sɔm tɛm dɛn de na di sem ples usay di fɔs tɔŋ bin de, sɔm tɛm dɛn na difrɛn say.

Bɔt mɛmba se ɔltin we dɛn kin no bɔt kansa kin difrɛn. Yu dɔktɔ kin tɛl yu di tin we go apin to di tritmɛnt (prognosis) bay di patikyula kayn kansa we yu gɛt, di stej we i gɛt, yu ɔl wɛl bɔdi, aw yu de du tritmɛnt, ɛn difrɛn ɔda tin dɛn. Yu dɔktɔ na di bɛst pɔsin fɔ advays yu bɔt aw dis diagnosis go afɛkt yu.

Tin dɛn we wi fɔ mɛmba frɔm dis stori (Take-Home Message)

If dɛn no se yu gɛt Spindle Cell Sarcoma, dat kin mek yu strɛs. De sik kin mek yu taya ɛn nɔr kin fil fayn. Bɔku tɛm, di tritmɛnt dɛn kin tranga, ɛn yu kin gɛt prɔblɛm dɛn lɛk fɔ yus to bon graft ɔ atifishal limb.

So, i rili impɔtant fɔ tɔk to yu dɔktɔ ɔnɛs ɛn opin wan frɔm di biginin. Dis we ya, yu kin ɔndastand aw yu gɛt di sik, aw yu go ebul fɔ mɛn yu kansa, wetin na di gol dɛm fɔ yu tritmɛnt, ɛn wetin yu go nid fɔ chenj yu layf we yu de trit yu ɛn we yu de wɛl.

Spindle cell sarcoma na siriɔs kansa we de gro fast fast. Bɔt sɔm tritmɛnt dɛn de we kin kɔntrol aw i de gro ɛn sɔm tɛm dɛn kin mɛn am kpatakpata. Tɔk to yu dɔktɔ bɔt wetin yu go ebul fɔ ɛkspɛkt. Nɔ ɛva giv ɔp op. Fɔ fala di rayt advays we dɔktɔ gi yu ɛn fɔ kɔntinyu fɔ gɛt gud maynd rili impɔtant fɔ dis fɛt.

Spindle Cell Sarkoma, Spindle Cell Sarkoma, Kansa, Bon Kansa, Sɔft Tisu Kansa, Tumɔr, Simptom, Tritmɛnt