Yu tink se i nɔ izi fɔ kɔntrol yu asma? Lɛ wi lan bɔt di Xolair vaysin fɔ siriɔs alɛji asma.

Bɔrku pipul dɛm wae gɛt asma kin kɔntrol dɛn sik wit wan tin wae de inhala ɛvride. Bɔt fɔ sɔm pipul dɛn, dis inhala nɔmɔ nɔ go du fɔ dɛn. Na so i bi to yu? We yu gɛt siriɔs asma, ɛn di mɛrɛsin dɛn we yu kin tek nɔ kin ɛp, i kin rili bi lod, nɔto so? Bɔt nɔ wɔri. Dis biɛn tɛm, dɛn dɔn kam wit nyu mɛrɛsin fɔ mɛn dɛn bad bad asma sik ya. Dɛn tin ya nɔto tin dɛn we dɛn kin yuz fɔ blo, bɔt na injɛkshɔn. Wan pan dɛn mɛrɛsin dɛn de na Xolair.

Aw Xolair de wok? Fɔs, lɛ wi ɔndastand smɔl bɔt asma.

Asma, fɔ tɔk am simpul wan, na wan sik we nɔ de dɔn ɛn we kin afɛkt wi lɔng dɛn. I kin mek wi aywe dɛn, di tiub dɛn we de kɛr briz go na wi lɔng dɛn, inflamɛns. Di mɔsul dɛn we de rawnd dɛn kin tayt bak. Dis swel ɛn tayt de mek di aywe dɛn rili sɛnsitiv. Sɔntɛnde, dɛn kin blok wit mכkus.

Pipul wae gɛt asma kin gɛt sɔm kayn sik lɛk wae dɛn kin kɔf, swɛt, nɔr kin ebul fɔ blo fayn, ɛn dɛn chɛst kin tayt. Wi kin kɔl dis "asma atak." Difrɛn rizin dɛn de, ɔ "triggers," we kin mek pɔsin atak.

Di men tin we kin mek sɔm pipul dɛn gɛt asma na alɛji . Di imyun sistɛm fɔ dɛn pipul ya kin riak pasmak pan sɔm tin dɛn. Wi kin kɔl dɛn tin ya alɛrjens . Fɔ dɛn pipul ya, we dɛn alɛrgen ya go insay di bɔdi, asma atak kin apin.

Di men gol fɔ trit asma na fɔ ridyus dis swel ɛn tayt na di lɔng dɛn. Dis kin mek i izi fɔ blo ɛn i kin mek di nɔmba fɔ di wan dɛn we gɛt asma nɔ bɔku.

Di drɔg we dɛn kɔl Xolair gɛt di aktif ingridiɛnt we dɛn kɔl omalizumab . I de wok bay we i de blok wan tin we dɛn kɔl Immunoglobulin E (IgE) na wi bɔdi. We wan alɛrjen we a bin dɔn tɔk bɔt go insay di bɔdi, wi bɔdi kin mek bɔku bɔku dis IgE. We dis IgE blok na di bɔdi fɔ pɔsin we gɛt alɛji asma, di bɔdi in rεspכns to alɛrjens ɛn di lכng swel de rεdכks.

Ɛnibɔdi we gɛt asma kin yuz dis mɛrɛsin?

Nɔ, bɔrku pipul dɛm wae gɛt asma kin kɔntrol dɛn sik bay wae dɛn de inhala ɔltɛm. Sɔntɛnde, dɛn kin kɔntrol di sik fayn fayn wan wit mɛrɛsin dɛn we dɛn kin tek bay mɔt.

Dɛn kin gi Xolair to pipul dɛn nɔmɔ we gɛt siriɔs asma we nɔ ebul fɔ kɔntrol dɛn sik dɛn pan ɔl we dɛn de yuz di ays doz we dɛn kin yuz fɔ inhala. Dɔn bak, fɔ yuz dis mɛrɛsin, dɛn fɔ dɔn tɛst yu na dɔktɔ ɛn kɔnfyus se yu gɛt alɛji to wan aeroallergen we kin de ɔltɛm, lɛk animal dander ɔ dɔst mit.

Aw yu kam fɔ no aw dis mɛrɛsin de wok?

Dɛn dɔn du bɔku klinik stɔdi fɔ no if Xolair sef ɛn i wok. Dɛn dɔn du dɛn tin ya pan big pipul ɛn pikin dɛn.

Ɔl di wan dɛn we tek pat pan dis stɔdi bin gɛt prɔblɛm fɔ blo ivin afta dɛn yuz di maksimal doz fɔ inhala. Dɛn bin kɔnfyus bak se dɛn gɛt alɛji, lɛk dɔst mit.

Fɔ tɔk am simpul wan, na so dɛn du di risach:

• Dɛn bin gi wan grup di Xolair vaysin. Dɛn bin gi di ɔda grup wan dɛmi vaysin, we na wan plesibo . Bɔt nɔbɔdi nɔ bin no wetin dɛn bin de gɛt.
• Dɛn bin tɛl ɔlman fɔ kɔntinyu fɔ yuz di tin dɛn we dɛn kin yuz fɔ blo ɔltɛm.
• Afta sɔm mɔnt, ɔlman in kɔtikosterɔyd inhala doz bin ridyus smɔl smɔl.
• Dɔn dɛn luk if di wan dɛn we tek Xolair bin gɛt mɔ rilif pas di wan dɛn we tek plasɛbo.

Wetin na di bɛnifit dɛn we di risach dɔn gi?

Tu men bɛnifit dɛn bin de klia wan.

1. Ridyus siriɔs asma atak: Di Xolair grup bin gɛt signifyant lɔwa nɔmba fɔ siriɔs asma atak pas di plasɛbo grup. Dis bin de ivin afta dɛn dɔn ridyus di inhala doz.

2. Abiliti fɔ ridyus di inhala doz: Na lɛk 75% pan di pipul dɛn we tek Xolair bin ebul fɔ ridyus dɛn ɛvride kɔtikosterɔyd inhala doz bay af, we yu kɔmpia am wit 50% nɔmɔ pan di wan dɛn we tek plasɛbo.

Aw dɛn kin yuz di Xolair vaysin?

Xolair na wan injɛkshɔn we dɛn kin put ɔnda di bɔdi . Dɛn kin gi am ɛvri 2 to 4 wik. Yu dɔktɔ go disayd ɔmɔs tɛm yu nid fɔ tek di injɛkshɔn, bay yu ej, wet, ɛn di lɛvɛl we di IgE de na yu blɔd. Dɛn kin gi di injɛkshɔn na di shɔl, bɛlɛ, ɔ bak na di ɔp an.

Di impɔtant tin na dat, dɛn kin gi di fɔs fɔs dos fɔ di vaysin ɔltɛm na ɔspitul ɔ klinik. Dis na fɔ wach if yu gɛt ɛni alɛji. Afta dat, if yu mit sɔm tin dɛn we yu fɔ du, yu dɔktɔ kin alaw yu fɔ injɛkt yusɛf na os.

Tu we de fɔ gɛt dis mɛrɛsin. Wan pan dɛn na tin we tan lɛk pen we dɛn kɔl ɔtoinjɛkta . Dis kin mek yu ebul fɔ injɛkt di vaysin izi wan we yu nɔ yuz sirinj ɔ nidul. Di ɔda wan na di sirinj we kin kam wit di nidul lɛk aw i kin bi. If yu gɛt alɛji fɔ lɛtɛks, nɔ fɔgɛt fɔ tɛl yu dɔktɔ bɔt am. Na bikɔs sɔm sirinj dɛn kin gɛt lɛtɛks.

Aw lɔng i kin tek fɔ mek pɔsin fil fri frɔm dis?

If di Xolair vaysin rayt fɔ yu, yu fɔ bigin fɔ fil fayn insay sɔm wiks . As tɛm de go, yu nɔ go gɛt bɔku asma atak. Yu kin ebul bak fɔ ridyus di doz fɔ yu kɔtikosterɔyd inhala.

If yu nɔ fil ɛni chenj afta sɔm mɔnt, tɛl yu dɔktɔ bɔt dat bak.

Sayd ɛfɛkt ɛn aw fɔ mɛn dɛn?

Pipul dεm wae de tek Xolair kin gεt sכmtεm rεspiretכri infεkshכn (trot we de at, kol). Di bɛst we fɔ mek dis nɔ apin na fɔ was yu an ɔltɛm, klin, ɛn nɔ de nia pipul dɛn we sik. Ɛn gɛt yu ɛni ia flu shot.

Na smɔl tɛm nɔmɔ, sɔm pipul dɛn kin gɛt siriɔs alɛji, we dɛn kɔl anafylaksis , afta dɛn dɔn gi dɛn di fɔs doz. Dis na wan sik we rili siriɔs. Na dat mek dɛn kin gi yu fɔs fɔs dos ɔltɛm na ɔspitul. Na de, di dɔktɔ dɛn we tren go wach yu ɛn rɛdi fɔ trit yu wantɛm wantɛm if ɛni prɔblɛm kam.

Apat frɔm dɛn tin ya, ɔda bad bad tin dɛn kin apin. If yu gɛt ɛni sayn we de mɔna yu, tɔk to yu dɔktɔ.

Prɔblɛm kin de wit ɔda mɛrɛsin dɛn?

Nɔr no siriɔs intarakshɔn de bitwin Xolair ɛn ɔda mɛrɛsin dɛm. Bɔt i impɔtant fɔ tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn (we dɛn gi yu ɔ we yu nɔ de it), vaytamɛn dɛn, ɛbul mɛrɛsin dɛn, ɛn sɔpɔtmɛnt dɛn we yu de tek.