Omusawo wo bw’akugamba nti omwana wo alina ADHD ( Attention Deficit Hyperactivity Disorder), ggwe ng’omuzadde, oboolyawo oba oyitiriddeko ebibuuzo n’ebikweraliikiriza. Oyinza okuba n’endowooza ez’enjawulo ku ddagala omwana ly’agenda okuweebwa n’ebizibu ebivaamu. Ebiseera ebisinga, eddagala erizimba omubiri lye lisooka okulondebwa eri ADHD. Naye eddagala lino terikola ku buli mwana. Abazadde abamu nabo batya okuwa omwana eddagala lino. Kale, bw’oba olowooza ku ngeri etali ya kuzimba, omusawo ayinza okukuwa amagezi ku kika ky’eddagala eriyitibwa SNRI. Leero, ka twogere ku SNRI zino kye ziri n’engeri gye zikolamu.
SNRIs kye ki?
Mu ngeri ennyangu, SNRIs (Serotonin-Norepinephrine Reuptake Inhibitors) kika kya ddagala erikozesebwa okujjanjaba okwennyamira. Zikola nga zongera ku miwendo gy’ababaka babiri ab’eddagala mu bwongo bwaffe. Ababaka bano tubayita obusimu obutambuza obusimu. Eddagala lino ebbiri ye serotonin ne norepinephrine.
Eddagala lino terikkirizibwa mu butongole kitongole kya FDA (Food and Drug Administration) okujjanjaba ADHD. Wabula singa abasawo bawulira nti lisinga kusaana era nga liyamba omulwadde, basobola okumuwa eddagala lino ‘off-label’, ekitegeeza ku mbeera endala etali embeera ekkiriziddwa. Kino kitera okukolebwa mu basawo mu Sri Lanka n’ensi yonna.
Eddagala lino eppya erya SNRI litwalibwa ng’eririna obukuumi era lirina ebizibu ebitono okusinga eddagala erya tricyclic antidepressants (TCAs) eryali likozesebwa edda.
Waliwo ebika bibiri ebikulu ebya SNRIs ebikebereddwa ku baana abalina ADHD:
1. Duloxetine: Kino kikkirizibwa okujjanjaba ekiwuubaalo n’okweraliikirira mu bantu abakulu. Okugatta ku ekyo, eddagala lino era likozesebwa okujjanjaba okweraliikirira mu baana abasukka mu myaka 7 n’embeera eruma eya fibromyalgia.
2. Venlafaxine: Lino ddagala erikkirizibwa okujjanjaba ekiwuubaalo n’okweraliikirira mu bantu abakulu. Wadde nga tekikkirizibwa mu butongole ku baana abali wansi w’emyaka 18 oba aba ADHD, abasawo oluusi bakiwandiika ‘off-label’.
SNRIs ziyamba zitya ku ADHD?
Kuba akafaananyi ng’obutoffaali bw’obusimu mu bwongo bwaffe bwe byogera. Ezo eziyamba mu mboozi eno, kwe kugamba, okuwanyisiganya obubaka, ze busimu obutambuza obubaka bwe twayogeddeko emabegako. Abasawo balowooza nti abaana abalina obulwadde bwa ADHD balina obuzibu obumu mu nkola y’ababaka dopamine ne norepinephrine. Okunoonyereza okumu kuzudde nti ne serotonin yeenyigiddemu.
Eddagala erizimba omubiri lyongera ku muwendo gwa dopamine mu bwongo. Eddagala lya SNRI lyongera ku muwendo gwa serotonin ne norepinephrine. Eddagala lino bwe lyeyongera, empuliziganya oba okuwanyisiganya obubaka, wakati w’obutoffaali bw’obusimu mu bwongo kubaawo bulungi.
Empuliziganya eno esobola okuyamba okulongoosa obudde bw’omwana okussaayo omwoyo , okulongoosa okufuga ebirowoozo , n’okukendeeza ku kukola ennyo n’enneeyisa ey’obusungu . Era kiyinza okuyamba omwana okufuuka omwana omuwulize era atafaayo nnyo.
Ebintu by’olina okumanya ng’okozesa eddagala lino
Singa omusawo w’omwana wo akuwa eddagala lya SNRI, emirundi mingi ajja kutandika ne ddoozi entono ennyo . Olwo mu wiiki ntono, bajja kwongera ku ddoozi mpolampola okutuusa omwana lw’anaafuna ddoozi esinga okubakolera. Kiyinza okutwala wiiki 2 ku 4 okulaba eddagala lino mu bujjuvu. Kale, tosattira n'ogamba nti, "Kino sinnatandika kutwala." Kikulu okubeera omugumiikiriza.
Eddagala lino lijja mu ngeri ya ddagala oba kkapu. Omwana wo bw’aba afuna obuzibu mu kumira empeke, eddagala erimu osobola okulinyiga n’otabula mu kintu ng’obulo. Yogerako n’omusawo wo ku nsonga eno.
Kikulu nnyo okumanya ebizibu ebiyinza okuva mu kumira eddagala lino n’obubonero obuyinza okubaawo singa olekera awo okulimira mu bwangu.
| Ebizibu Ebitera okubaawo | Obubonero bw’okuggwaamu amaanyi |
|---|---|
| |
| Ekisinga obukulu: Buulira omusawo wo mu bwangu ku bikolwa bino byonna oba enkyukakyuka mu nneeyisa y’omwana wo. Tokyusa mu ddoozi oba okuyimiriza eddagala mu bwangu nga tosoose kwebuuza ku musawo. | |
SNRIs zikola zitya ku ADHD?
Kino kye kintu kye twetaaga okwogerako mu bwesimbu. Wabaddewo okunoonyereza okumala emyaka mingi ku ddagala eriweweeza ku ADHD, era wakati wa 70% ne 90% ku bantu abalikozesa balaga okulongoosa okw’amaanyi mu bubonero bwabwe.
Wabula waliwo okunoonyereza okutono ennyo ku bulungibwansi bwa SNRIs ku ADHD. Mu kunoonyereza okutonotono okutonotono ku ddagala lya venlafaxine, wakati wa kimu kya kusatu n’ebitundu bibiri ku bisatu eby’abaana abeetabye mu kunoonyereza kuno baalaga okulongoosa mu bubonero (naddala okukola ennyo n’obutafaayo). Wabula bangi baava mu kunoonyereza kuno olw’ebizibu ebyavaamu. Okunoonyereza okumu ku duloxetine nakyo kyalaga nti waliwo okulongoosaamu. Kale, tetusobola kugamba n’okutuusa kati nti bino bikola bulungi ng’ebizimba.
Obulabe ki obusinga obunene obuli mu SNRIs?
Kino kye kintu ky’osaanidde okusinga okussaayo omwoyo ng’omuzadde.
Eddagala lino lirina okulabula okw’enjawulo, okw’akabi ennyo okuyitibwa okulabula kwa ‘black box’. Kino kitegeeza nti, okufaananako n’eddagala lyonna eriweweeza ku kweraliikirira, eddagala lino liyinza okwongera ku bulabe bw’okulowooza oba ebikolwa eby’okwetta mu baana n’abavubuka naddala nga basoose kutandika kumira ddagala eryo .
Oyinza okutya ennyo ng’owulira bino. Naye ekyo tekitegeeza nti tolina kuwa mwana wo ddagala lino. Naye kitegeeza nti olina okwegendereza ennyo n'okubeera obulindaala . Olina okufaayo ennyo ku nkyukakyuka mu nneeyisa y’omwana wo n’embeera ye.
Omwana wo:
- Bw’oba olaga obubonero bw’okwennyamira, .
- Bw’oba oyogera ku kwetuusaako obulabe,
- Bwe twogera ku kufa, .
- Bw’oba olaga enkyukakyuka ezitali za bulijjo, ez’amangu mu nneeyisa, .
Kuba essimu y’omusawo mu bwangu, awatali kulwa. Oba mutwale mu ddwaaliro eriri okumpi mu kitongole ky’abalwadde ab’amangu (ETU). Tonyooma bulabe buno.
Obubaka Obutwala Awaka
- SNRIs ngeri ndala mu kifo ky’eddagala erisitula obulwadde bwa ADHD. Mu butuufu kika kya ddagala eriwonya okwennyamira era likozesebwa ‘off-label’ ku ADHD.
- Kiyinza okutwala wiiki eziwera okulaba engeri eddagala lino gye likola mu bujjuvu, n’olwekyo kikulu okubeera omugumiikiriza.
- Tokyusa mu ddoozi y’eddagala lyo oba okulekera awo okulimira mu bwangu nga tolina magezi ga musawo. Okukola ekyo kiyinza okuvaako ebizibu ebivaamu.
- Obulabe obusinga okuba obw’amaanyi kwe kusobola okulowooza ku kwetta mu biseera ebisooka eby’eddagala. Weegendereze nnyo enneeyisa y’omwana wo.
- Yogerako mu lwatu n’omusawo wo ku bibuuzo byonna, ebikweraliikiriza oba ebizibu omwana wo by’ayinza okuba ng’afuna. Empuliziganya ennungi wakati wo n’omusawo wo yeetaagibwa nnyo mu mbeera y’omwana wo.
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