I taksa hian chhungril atangin a do che niin i hria em? Antisynthetase Syndrome a ni thei!

A châng chuan chhûngril aṭangin thil engemaw tibuaitu che angin i inhria em? I ruhte a na mai mai emaw, thawk a harsa deuh emaw a ni thei a, i vunah inthlak danglamna tenau engemaw zat pawh i hmu thei bawk. Hengte hi thil thleng anga ngaih mai mai suh. A chang chuan an hnung lamah hian thawnthu buaithlak zawk a awm thin. Vawiin hian natna hlauhawm tak, mahse enkawl theih tak Antisynthetase Syndrome tih kan sawi dawn a ni.

Antisynthetase Syndrome hi eng nge ni? A awlsam zawngin...

Antisynthetase Syndrome hi a awm lo hle. Hemi a thil thleng chu kan taksa pum puiah hian inflammation a awm a, chu chu inflammation ang chi condition a ni. Hei hi a takah chuan autoimmune disease a ni. Tunah chuan autoimmune disease chu eng nge ni tih i zawt ta a ni.

Kan taksa hian immune system a nei tih han ngaihtuah teh . Kan ram humhalhtu sipai ang mai a ni. He system chhunga cell leh taksa peng hrang hrangte hian natna thlentu hrik, bacteria leh virus lakah min venghim a ni. Mahse, autoimmune disease-ah chuan he defense system hi a kal sual thin. Kan cell leh tissue hrisel tak takte chu "hmêlma" niin a ngai a, a bei tan ta a ni. Keimahni sipai ngeiin mahni in an rawn bei ang mai a ni. Doctor-te pawhin hetiang thil hi a thlen chhan chiang takin an la hre thei lo.

Antisynthetase Syndrome-ah hian kan taksa hriselna (immune system) hian kan taksa hmun hrang hrang a nghawng thei a ni:

• Muscle te hi a ni
• Joints te pawh a awm
• Chuap
• Vun
• Thisen kalna kawng

A pawimawh ber chu ruh natna thar, vun inthlak danglam emaw, thawk harsa emaw i hmuh chuan, ngaihthah lovin doctor pan tur a ni.

He natna hi engtiang chiahin nge a tlem?

Hei (Antisynthetase Syndrome) hi natna hmuh tur awm lo tak a ni . Mi engzat nge nei tih chiang taka sawi a har khawp mai. A chhan chu kum tin case tlemte chauh an report thin vang a ni. A châng chuan, heng chhinchhiahnate hi natna dang chhinchhiahnate nên a inang a, hriat lohvin a awm thei bawk.

Antisynthetase Syndrome natna lan chhuah dan chu engte nge ni?

Eng symptoms nge i neih tih chu i taksaah i immune system a thawh that dan leh a tihchhiat nasat danah a innghat ang.

Vawi tam tak chu Antisynthetase Syndrome vei te hian natna dang engemaw zat inzawmkhawma symptom an nei thin. Eng nge an nih hi han thlir ila:

• Myositis: Hei hi hun rei tak chhung taksa ruh natna a ni. Hei hian taksa ruh a ti na a, chak lohna a thlen bawk.A thleng thin. Ngaihtuah teh, i chak lo lutuk a, i kut pawh i chawi thei lo. A châng chuan i kawr ruhte chu a chak lo va, ei leh in tur ei harsa a ti ṭhin. Chu chu dysphagia kan ti a ni .

• "Mechanic kut": Hei hi hming mak deuh a ni lo maw? Hei hi kutphah leh kut zungtang sir vun a thim leh a chhe na hmun a ni. Nilengin grease leh oil hmanga hnathawk mechanic kut ang mai a ni.

• Interstitial lung disease (ILD): Hei hi kan lung chhunga boruak bawm te tak te (alveoli) leh a chhehvela thisen kalna kawng inkar tissue a chhiat hian a ni. Hei hian thawk hah (dyspnea) , khuh vawt , hahna , leh rilru hahna a thlen thei a ni. Stairs atanga tla thla ang mai a ni.

• Polyarthritis: Hei hi ruh panga emaw a aia tam emaw a ruala natna a awm chuan a ni. Hei hian ruhte a ti na a, a tikhauh a, a ti hring bawk . Zing i thawh chuan i rilru a hah mai thei.

• Raynaud’s phenomenon (secondary Raynaud’s syndrome): Hetah hian kut zungtang leh ke ruhte chu a rawng a inthlak (a rawng a dum a, a rawn sen a, a rawn sen a, a rawn sen) a, a bik takin khaw lum a nih chuan a hring chhuak thin. Freezer atanga ice cube i lakchhuah hnua i kut zungtang a hrual ang mai a ni.

• Khawsik: Mi thenkhat chuan an taksaah natna hrik awm lovin khawsik an nei mai thei. Chumi awmzia chu he immune system hnathawh avang hian taksa lumna a sang tihna a ni.

Eng thilin nge Antisynthetase Syndrome hi a thlen?

He natna thlen chhan dik tak hi hriat a la ni lo . Mahse doctor-te chuan he natna vei tam tak hian an thisenah antibody chi khat bik an nei tih an hmuchhuak a. Heng antibodies te hian an immune system hian anmahni taksa venghim lovin anmahni taksa a bei tih a tilang a ni. Hengte hi (autoantibodies) kan ti a, chu chu "self-antibodies" tihna a ni.

Tunah chuan en teh, antibody hi kan taksaa thil tha lo a luh chuan min vengtu protein a ni. Kan immune system hmanga chemical signal ang mai an ni. Heng antibodies te hian bacteria leh virus ang chi invader tha lo tak takte chu "hlauhawm" tiin an chhinchhiah a ni. Mahse autoimmune disease i neih chuan i immune system hian tihsualin antibodies a siam chhuak a, chu chuan tissue hrisel tak tak a bei thin.

Antisynthetase Syndrome vei te hian autoantibodies an nei tlangpui a , chu chuan enzyme tRNA synthetases an tih chu a bei thin . Heng tRNA synthetases te hi enzyme pawimawh leh tangkai tak tak an ni a, kan taksain a hnathawh that theih nan a mamawh a ni.

Engvangin nge kan immune system hian heng autoantibodies te hi a siam tan tih hi thuruk a la ni reng. Mahse, i thisena heng autoantibodies te hi evidence i neih chuan Antisynthetase Syndrome i neih a rinawm hle.

Hetiang hi a ni, i in hmaah mi pakhatin meipui a hal ang tih han mitthla teh. A tuk zingah i en chuan halmawi chi hrang hrang leh kawngpui kangte chu leiah a darh zau vek a. Tuin nge meipui chu a kap tih chiang takin i hre lo mai thei, engtikah nge a kah tih leh engvangin nge a kap tih i hre lo mai thei. Mahse a thleng tih finfiahna a awm. Antisynthetase Syndrome-ah hian meipui i hal laia thawm i hriat leh ui te hlauhthawn ai chuan a hmaa kan sawi tawh ang kha i tawng thin.

He natna vei theihna hlauhawm ber chu tute nge ni?

Tu pawhin Antisynthetase Syndrome an nei thei. Amaherawhchu, hmeichhia leh kum 50 chunglam te hian he natna hi an vei tam zawk a ni. Hmeichhia hian he natna hi mipa aiin a let hnih velin an vei tam zawk a ni.

Engtin nge Antisynthetase Syndrome hi hmuhchhuah a nih?

Doctor chuan he natna hi i natna lan chhuah dan te, taksa enfiahna te, leh test dang engemaw zat a zirin a hmuchhuak thin.

Autoimmune diseases lama tui doctor, rheumatologist tia koh chu i pan a ngai mai thei. A enfiah ang che a, i symptoms te a zawt ang che. I natna lan chhuah dan te, engtikah nge i hriat hmasak ber tih te, eng thil pawhin a ti na zual em tih te chu doctor hnenah i hrilh a ngai dawn a ni.

Tin, Antisynthetase Syndrome i vei tih finfiah nan leh chutiang bawka symptoms nei thei dinhmun dang pawh paih chhuah nan test engemawzat i neih a ngai bawk ang.

Natna hriat theih nan eng test nge hman thin?

Test pakhat mah hian hei hi chiang takin a nemnghet thei lo. Hei hi hriatchhuah hi a tlangpuiin differential diagnosis an tih process pakhatah a tel a ni . Chumi awmzia chu i doctor chuan i natna lan chhuah chhan zawng turin test eng emaw zat a kalpui ang a, natna dang a paih chhuak ang a, a tawpah chuan Antisynthetase Syndrome i nei tih a hmuchhuak ang che tihna a ni. Test i neih theih thenkhat chu:

• Thisen test: I immune system hnathawh dan enfiah tur leh autoantibodies i neih leh neih loh enfiah nan, chu chu Antisynthetase Syndrome chhinchhiahna a ni. Thisen test hian taksa ruh a chhiat chuan thisenah enzyme thenkhat chhuak a sang em tih pawh a enfiah thei bawk.
• Urinalysis: Kidney function enfiah nan leh i symptoms thlentu tur infection emaw, zun chhunga harsatna dang emaw a awm leh awm loh enfiah nan.
• Pulmonary function tests: I lung emaw thawkna lam emaw a nghawng em tih enfiah thin ang che.
• Computed tomography (CT) scan emaw imaging test dang emaw: Taksa chhunga tissue leh organ hrang hrangte thlalak lak.
• (Electromyography - EMG) tih a ni a:Muscle hnathawh dan enfiah rawh.
• Magnetic resonance imaging (MRI) scan hmanga taksa ruh natna te: inflammation enfiah nan.
• Biopsy hi test a ni a, chu chu taksa ruh emaw, lung tissue emaw te tak te lak a ni.

Antisynthetase Syndrome hi engtin nge enkawl a nih?

Antisynthetase Syndrome hi damdawi a awm lo . Mahse, i doctor chuan i natna lan chhuah dan control thei tur, i nitin nunah nghawng a neih tihziaawmna tur leh i taksa peng hrang hrangte tihchhiat tlem thei tur damdawi inzawmkhawm zawng turin a pui thei che a ni.

I mamawh enkawlna chi chu i natna lan chhuahna hmun leh a nasat danah a innghat ang. Damdawi hman tlanglawn tak tak thenkhat chu hetiang hi a ni:

• Corticosteroids: Hengte hi damdawi prescription a ni a, natna leh hliam tihziaawmna a ni. Doctor-te chuan immunosuppressant an tih damdawi bakah corticosteroid an pe tlangpui.
• Immunosuppressants: Heng damdawi te hian i immune system hian cell leh tissue hrisel tak tak a beih loh nan a titawp a ni. Damdawi i mamawh chi chu eng organ nge a nghawng danah a innghat ang. Immunosuppressant hman tlanglawn ber chu methotrexate, azathioprine, leh mycophenolate te an ni. Cyclophosphamide, rituximab, emaw tacrolimus emaw pawh i mamawh thei bawk.
• Interstitial Lung Disease (ILD) enkawlna: Thâwk awlsam zawk nan damdawi pek i ni thei a, oxygen pek belh i mamawh chuan oxygen therapy pek i ni thei bawk. I thawk lama harsatna i neihte enkawl turin pulmonologist nen thawhhona i neih a ngai dawn a ni.
• Physical therapy: Physical therapist hian i taksa chetna range tihchangtlun nan a pui thei che a ni. Muscle-related symptoms enkawlnaah an pui thei a, i lung tichak turin thawkna exercise an rawt thei bawk. Pulmonary rehab pawh i mamawh thei bawk .

Antisynthetase Syndrome ka neih chuan eng nge thleng ang?

I doctor chuan i natna lan chhuah dan tur enkawl thei tur enkawlna hrang hrang zawng turin a pui thei che a ni.

Antisynthetase Syndrome hi natna khirh tak a ni a . Hei hian a awmzia chu hun rei tak (i ​​dam chhung zawng pawh a ni thei) symptoms te chu i enkawl a ngai dawn tihna a ni.

(Antisynthetase Syndrome) hian thihna a thlen thei em?

Antisynthetase Syndrome hi a tlangpuiin thihna a thlen lo . He natna vei dam rei zawng hi a tlangpuiin a nghawng nasa lo hle. Mi tam tak chu he natna hi an dam chhung zawngin an khawsa a, mahse enkawlna hmangin an natna lan chhuah dan chu an thunun thei a ni.

Mahse, interstitial lung disease na tak emaw, i thawkna kawng tichhe thei complication dang emaw i neih chuan thihna a thlen thei a ni. Mahse a tlem hle. I doctor chuan i beisei tur a hrilh ang che a, eng symptom danglam nge chu thawkna lama harsatna nasa tak lanchhuahna hmasa ber ni thei tih a hrilh bawk ang che.

Antisynthetase Syndrome ka vei loh nan ka veng thei ang em?

Antisynthetase Syndrome hi ven theih dan tur a awm lo a , mithiamte chuan eng thil nge a thlen tih leh eng thilin nge a hlauhawmna a tipung tih an hre chiang lo.

Engtikah nge Doctor ka hmuh ang?

Symptom thar i neih chuan, a bik takin a na zual a nih chuan doctor pan rawh . I natna lan chhuah dan chu i enkawlna nen a hma angin a thunun theih loh nia i hriat chuan, emaw, i natna lan chhuah danin nitin hna i thawh a harsat phah a nih chuan, i doctor nen inbia ang che.

Engtikah nge emergency room-ah ka kal ang?

Heng symptoms te hi i neih chuan emergency room-ah kal nghal la emaw 911 (or i awmna hmuna emergency number) ah call rawh :

• Thâwk harsa nghal.
• Thâwk hahna nasa tak (thâwk thei lo ang maia inhriatna).
• Vun, hmui, kut zungtang (cyanosis) rawng dum.
• Chhuak na emaw, a rit emaw.

Doctor hnenah eng zawhna nge ka zawh ang?

• Antisynthetase Syndrome emaw autoimmune natna dang emaw ka nei em?
• Eng ang test nge ka tih ang?
• Ka symptoms control nan eng treatment tha ber ber nge ni?
• Physics therapy emaw, thawkna lama harsatna emaw ka mamawh ang em?
• Engtiang chiahin nge lung complication na tak ka neih theih?

Antisynthetase Syndrome tih hming dang engte nge ni?

Doctor-te chuan Antisynthetase Syndrome hi hming dangin an ko \hin. Entir nan:

• (Antisynthetase tlakchhamna natna) .
• (AS syndrome) (AS syndrome) tih a ni.
• (Anti-Jo1 syndrome) tih a ni.

Heng zawng zawng hi dinhmun inang hming hrang hrang an ni.

A tawp berah chuan hriat reng tur (Take-Home Message) .

Antisynthetase Syndrome hi natna hlauhawm tak a ni a, i immune system hian i taksa a venghim a, i taksa a bei zawk thin. I natna lan chhuah danin i nitin nunah nghawng a neih tlem theihna tura pui thei tur enkawlna chungchang i doctor nen sawiho rawh.

Autoimmune natna nena nun hi a lungchhiatthlak hle thei – i taksain a bum che ang maiin a lang thei. I nunah inthlâk danglamnate nena insiamrem tûr emaw, chu natna hmachhawn tûr emawa ṭanpuina i mamawh a nih chuan, i doctor hnênah rilru lam hrisêlna lama counseling lak theih dân tûr zawt rawh. Lungngaihna leh lungngaihna hi thil pangngai a ni a, mahse nangmah chauhin i paltlang a ngai lo.

`Antisynthetase Syndrome, autoimmune natna, myositis, interstitial lung natna, Raynaud-a phenomenon, autoantibodies, ruh natna, taksa ruh chak lohna