Cancer i vei tih i hriat chuan hlauhna leh mangang tak tak i nei thin. Tichuan, Doctor ten a enkawl dan tur an sawi chuan damdawi thar leh thu thar i hriat thiam loh tam tak i hre thin. A châng chuan heng thilte hi i hriatthiam loh chuan i hlauhna a zual lehzual ṭhin. Avastin hi cancer enkawlna atana hman thin damdawi danglam deuh a ni . Chuvangin vawiin hian he damdawi Avastin (Bevacizumab) tih hi i hriatthiam theih tur awlsam takin i sawi dawn nia.
A hmasain he damdawi hi eng Angiogenesis inhibitor nge a nih tih hi han en ila.
Hei hi hrethiam tur chuan entirnan awlsam tak hmang ila. Kan huana hnim hring hring ang maia cancer cell tumor lo chhuak chu han mitthla teh. He hnim hi huan pum puia lo thang leh darh tur hian eng nge a mamawh? Tui a mamawh tak zet a ni. Chutiang bawkin cancer tumor hian taksa peng dangah a lo thang lian a, a darh theih nan thisen supply a mamawh bawk.
Chuvangin he cancer hi a finthlak hle. Kan taksaah thisen mamawh a hmuh theih nan leh thisen kalna kawng thar siam turin “signal” a thawn a ni . Chu weed plant chuan tui rawn thlen turin lei hnuaiah pipe system thar a tipung ang bawkin. Damdawi angiogenesis inhibitor an tih hian heng thisen kalna kawng thar te hi a titawp thin. Chu chu cancer-a kal “thisen kalna kawng” te chu an block tihna a ni. Tichuan, thisen supply a bo chuan cancer chu a lo thang lian thei lo va, a darh thei lo bawk.
Chuti a nih chuan engtin nge Avastin (Bevacizumab) hian hna a thawh?
Avastin hi damdawi a ni a, a chunga kan sawi tawh ang khan Angiogenesis inhibitor class a mi a ni. A dik tak chuan hei hi damdawi class bik Monoclonal antibody tih a ni.
Tunah chuan monoclonal antibody chu eng nge ni tih i ngaihtuah mai thei. A awlsam zawngin sawi ila, laboratory-a a bik taka siam, kan taksain natna dona atana a pianphung atanga a siam antibodies nen a inang, synthetic protein a ni. Hemi chungchanga thil danglam tak chu chemotherapy damdawi pangngai angin taksaa cell zawng zawng a nghawng lo va, targeted therapy- a cancer cell chauh a nghawng a ni
Avastin hian VEGF (Vascular Endothelial Growth Factor) chu a target a, hei hi a hlawhtling hle.A molecule chu. Kan sawi tawh ang khan cancer hian thisen kalna kawng thar siam turin “signal” a thawn a, chu signal chu VEGF a ni. Avastin hian a tih chu he VEGF molecule hi a inzawm a, hnathawh a titawp a ni. Signal “off” ang mai a ni. VEGF hian hna a thawh tawh loh chuan thisen kalna kawng thar a lo piang lo va, cancer hian a ei leh in a hloh ta a ni.
Avastin ka ei chuan chemotherapy ka mamawh em?
Ni e, hei hi mi tam tak tan chuan harsatna a ni. Avastin hi targeted therapy ni mahse, a mah chauhin a thawk lo . Supporting actor ang mai a ni. A thawnthua a changtu ber, chemotherapy chu a la mamawh hle.
Chemotherapy hi damdawi chi khat chak tak a ni a, rang taka inthen darh cell (cancer cell ang chi) te chu a that thei a ni. Avastin hian chemotherapy puiin hna a thawk a ni.
Mahse a tha ber chu, Avastin hi chemotherapy nen an inzawm chuan chemotherapy result chu a hlawhtling zawk a ni. Chu chu heng damdawi pahnih hi an inkawp chuan cancer dona chu a chak lehzual tihna a ni. Tumor-a thisen kalna a tihtlem avangin chemo damdawi hian cancer cell te chu a that a ni.
Avastin hmang hian eng cancer chi nge enkawl?
Avastin hi cancer chi hrang hrang tan phalsak a ni . Mahse, cancer zawng zawng tan pek a ni lo. I doctor chuan he damdawi hi i tan a tha em tih chu i cancer chi hrang hrang, a stage leh i hriselna zawng zawng a zirin a rel ang.
A hnuaia table-ah hian Avastin hmanna cancer chi hrang hrang zingah a langsar ber berte tarlan a ni.
| Cancer chi hrang hrang | Thu pawimawh tak tak |
|---|---|
| Colon emaw Rectal Cancer emaw a awm thei | Cancer hian taksa peng dangah a darh tawh (metastatic)-ah hman a ni ber. Chemotherapy damdawi 5-fluorouracil (5-FU) emaw capecitabine (Xeloda) emaw nen pek thin a ni. |
| Lung Cancer a ni | Lung cancer hmasawn chi thenkhat tan hman a ni. |
| Kidney Cancer a ni | Metastatic renal cell carcinoma tan hman a ni. |
| Ovarian Cancer a ni | Ovarian cancer vei thenkhat enkawlna atan hman a ni. |
| Cervical Cancer a awm a ni | Cervical cancer lo awm leh tawh emaw, darh zel emaw tan hman thin. |
| Glioblastoma natna a ni | Hei hi thluak cancer chi khat a ni a, he enkawlna hi a lo let leh chuan pek theih a ni. |
Avastin hi hnute cancer vangin pek a ni lo em ni?
Tun hmain Avastin hi hnute cancer enkawlna atan hman ni mah se, a hnu lama zirchianna hrang hrangah chuan he damdawi hian a thatna aiin a side effects a hlauhawm zawk tih a nemnghet a ni. Chuvangin, United States-a FDA ang institution te chuan hnute cancer tan Avastin hman hi an pawm tawh lo.
Avastin hian colon cancer hi a tidam kim thei ang em?
No. Avastin hi cancer tidam vek thei tur “magic” damdawi a ni lo . Mahse, clinical trial-ah chuan he damdawi hian damlote dam chhung nasa takin a ti rei thei tih hmuhchhuah a ni . Entirnan, zirchianna thenkhatah chuan Chemotherapy hmanga Avastin dawngtu damlote chu chemotherapy chauh dawngtu damlote aiin thla 5 vel an dam rei zawk tih hmuhchhuah a ni. Cancer dotu tan chuan he hun hi a hlut zia kan hria.
Avastin hian eng side effect nge a neih?
Damdawi chak tak ang bawkin Avastin hian side effect a nei thei a ni. Mahse, a ei zawng zawng hian heng side effects te hi an nei vek dawn lo . Amaherawhchu hei hi hriat chian a pawimawh hle. Hei hian symptoms eng pawh i hriat theih nan leh doctor hnenah i hriattir nghal ang.
A hnuaia tarlan te hi side effect na tak leh tlanglawn tak tak awm thei thenkhat te an ni.
| Avastin hian a nghawng tha lo hle | |
|---|---|
| Side effect a awm thei | Hemi chungchangah hian eng nge hriat tur |
| Side effect na tak tak, doctor hnena hriattir nghal tur | |
| Gastrointestinal perforation a awm thin | Hei hi dinhmun pawi tak a ni. A lan chhuah dan chu pum na na tak, khawsik leh rilru hahna te a ni thei. Surgery neih a ngai mai thei. |
| In chhungril lama thisen chhuak | Hei hian nunna atana hlauhawm tak tak, stroke ang chi a thlen thei a ni. |
| Hliam dam rei lutuk | Doctor chuan a bik takin he damdawi hi operation hma emaw, operation hnu emawa pek hi a fimkhur hle. |
| Lung lam chak lohna | A bik takin thinlung tichhe thei chemo damdawi dang nena ei hian a hlauhawmna a sang hle. |
| Kidney a chhiat phah | Zun-a protein tam lutuk ang chi symptoms a awm thei. |
| Side effect dang awm fo (doctor hriattir) . | |
| Thisen sang lutuk | Enkawl lai hian thisen sang enfiah fo a pawimawh. |
| Chau | Hei hi chemotherapy avanga side effect awm fo a ni bawk. |
| Thisen chhuak chu thisen kalna kawng (veins) ah a awm | Ke hring leh na ang chi symptoms te chu fimkhur rawh. |
| Diarrhea, lu na, chaw ei chak lohna, hmui natna | Hengte hi a tlangpuiin manageable side effects an ni. |
| Thisen chu zun chhungah a awm | Hei hi i hriat chuan doctor hnenah i hriattir nghal tur a ni. |
A pawimawh ber chu, heng symptoms te hi i neih chuan, "Hei hi engmah a ni lo" tih mai mai suh. I doctor emaw, i enkawlna hmuna damdawi in department kaihhnawih emaw hnenah hriattir nghal rawh. I report hma chuan condition enkawl a awlsam zawk ang.
Take-Home Thuchah a ni
- Avastin (Bevacizumab) hi hmanlai chemotherapy damdawi a ni lo. Target therapy a ni a, cancer cell-a thisen pe chhuaktu thisen kalna kawng siam a titawp a ni.
- He damdawi hi a ringawt hman a ni tlangpui lo. A thatna tihpun nan chemotherapy nen pek dun a ni.
- Hei hi cancer chi hrang hrang, colon, lung, kidney, leh ovarian te tan chauh hman a ni.
- Side effect na tak tak a awm theih avangin enkawl laiin i doctor hnenah symptom danglam tak tak i neih chuan hriattir nghal a pawimawh hle.
- Nangmah emaw, i hmangaih tak emaw chu cancer enkawlna atan Avastin pek a nih chuan, zawhna emaw, ngaihtuahna emaw i neih apiang chu i doctor nen sawiho ngei ang che . Anni hian thu dik ber an rawn pe thei ang che.
Avastin, Bevacizumab, cancer, cancer enkawlna, chemotherapy, angiogenesis inhibitor, cancer damdawi, side effects, pilika prathikara, anathuru abada, cancer enkawlna sinhala
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