Hnute cancer tih thumal kan hriat hian mi tam tak chuan hlauthawng deuhin kan awm thin. A bik takin i nu emaw, i farnu emaw, i farnu emaw hian he natna hi a vei tawh a nih chuan "Aw, kei pawhin ka vei dawn em?" Chuvangin hetiang cancer vei theihna hi hereditary risk a awm leh awm loh hriat theihna tur special genetic test a awm a ni. Chu chu vawiina kan sawi tum chu a ni. Mahse hei hi mi zawng zawng mamawh a ni em? Fiah tak leh awlsam takin i hrethiam ang u.
Breast cancer zawng zawng hi thlahtute atanga lo chhuak a ni tak tak em?
A hmasain he ngaihdan dik lo hi i paih bo ang u. Hnute cancer tam zawk hi thlahtute atanga lo chhuak a ni lo. Dik tak chuan hnute cancer hmuhchhuah tam zawk hi kan tar chhoh zel a kan taksa cell genes inthlak danglamna (mutations) vang a ni. A awlsam zawngin kan taksa cell-te a inthen darh hian a chang chuan tihsual tenau te a thleng thin. Heng tihsualte hi kan tar chhoh zel chuan a pung thei a ni. Chu chu cancer tam zawk thlentu a ni.
Mahse, za zela tlemte tan chuan, hmeichhe 100 zinga 5 leh 10 inkar, hnute cancer vei , he cancer thlentu hi gene dik lo, rochun a ni. Phên dangin sawi ila, an chhungkuaah he cancer vei theihna hi thlah khat atanga thlah dangah a darh zel a ni.
A pawimawh ber chu i chhungkuaa tumahin hnute cancer an vei loh vang mai mai chuan i vei dawn lo tihna a ni lo. Tin, i chhungkuaa mi pakhatin a neih tawh vang mai mai chuan nang pawhin i hmu ngei ang tihna a ni lo.
Heng genes te hi BRCA1 leh BRCA2 an tih te hi eng nge ni?
Herditary breast cancer chungchang kan sawi hian kan hriat fo thin hming pahnih chu BRCA1 (Braca One) leh BRCA2 (Braca Two) te an ni. Hengte hi a takah chuan kan taksaa gene pangngai an ni. An hna ber chu cell chhiat huna siam that leh cancer cell siam dan control hi a ni. Taksa ngeiin a invenna ang mai a ni.
Mahse a châng chuan heng BRCA gene-ah hian chhiatna, a nih loh leh mutation a awm thei a ni. Chutiang gene chhia chu thlah khat atanga thlah khata rochun a nih chuan chu humhimtu chuan hna a thawk tha lo. Chu chu hnute cancer leh ovarian cancer vei theihna a sang hle a ni.
Ngaihtuah teh, .
- A vaiin hmeichhiain a dam chhungin hnute cancer a vei theihna chance chu 13% vel a ni.
- Mahse BRCA1 gene mutation nei tan chuan he risk hi 55% leh 85% inkar ah a pung thin .
- Ovarian cancer vei theihna pawh a sang hle bawk.
- Thil pawimawh dang chu heng BRCA gene- related cancer te hi a tlangpui aia kum naupang zawkah a awm thei tih hi a ni.
Khawvel hriat hlawh actress Angelina Jolie ang mite chuan he BRCA gene mutation hi an vei tih hmuhchhuah a nih hnuah, chutiang hlauhawmna sang tak avang chuan cancer a lo awm hmain an hnute leh ovary te chu lakchhuah tumin operation an nei a ni.
Chuti a nih chuan tuin nge he test hi ngaihtuah ngai?
Hei hi zawhna pawimawh ber a ni. A chhanna chu, mi zawng zawng hi test neih a ngai lo. Chhungkaw cancer i neih loh chuan he BRCA gene mutation hi i neih theihna chance a hniam hle.
Mahse, i chhungkaw history-ah a hnuaia mi hi i neih chuan , he test chungchangah hian i doctor nen inbiakna neih a tha hle.
| Chhungkaw history-a risk tipungtu | A awlsam zawngin... |
|---|---|
| First-degree chhungte hnute cancer vei neih | I nu, i farnu emaw, i fanu emaw chuan hnute cancer a vei tawh a nih chuan, a bîk takin kum 50 a tlin hmain . |
| Chhungkaw pakhata mi eng emaw zatin hnute cancer an vei tawh a ni | Entîr nân, i nu lam aṭanga mi engemaw zât, i pi, i nu, leh i pi te chu cancer an vei tawh a nih chuan. |
| Chhungkaw member ovarian cancer vei neih | Ovarian cancer hi hnute cancer aiin a tlem zawk a, chuvangin chhungkaw history-a natna vei neih hi risk factor chak tak a ni. |
| Chhungkaw member mipa pakhatin hnute cancer a nei a | Hei pawh hi a tlem hle. Chuvangin chhungkaw zinga mipa pakhatin hnute cancer a vei tawh a nih chuan chu pawh chu risk factor chak takah ngaih a ni. |
Test i lak hmain eng nge i tih tur?
A chunga kan sawi tak risk factors te hi i neih chuan hlau suh. I tih hmasak ber leh pawimawh ber chu i chhungkaw doctor emaw gynecologist emaw hmu la, hei hi chipchiar taka sawiho hi a ni.
Lab-ah direct-in kal la, hetiang hian genetic test hi ti ngai suh, a chhan chu he test result hian i chhungkaw dangte ang bawkin i nun a nghawng thei a ni.
I doctor chuan i chhungkaw chanchin a enfiah ang a, he test hi i mamawh leh mamawh loh a rel ang. A tul chuan genetic counseling atan a refer thei che a ni . Chutah chuan specialist chuan test chungchanga i hriat tur zawng zawng te, result awmzia te, result a zirin eng step nge i tih tur tih te a hrilhfiah ang.
Cancer lo kir leh theihna tur test dang
BRCA test bakah hian genetic test dang pawh a awm a, chu chuan hnute cancer nei tawh (stage 1 emaw 2 emaw) leh enkawl mek chu cancer lo kir leh theihna tur leh chemotherapy engzat nge a mamawh dawn tih hriat theih nan a pui thei a ni. Chung zinga ṭhenkhat chu:
- Oncotype DX: Test hman lar tak a ni a, cancer lo lang leh theihna tur score pe turin gene 21 a zirchiang a ni.
- Mammostrat: Gene 5 a zirchiang a, risk chu low, medium, high tiin a categorize a.
- MammaPrint: Gene 70 a zirchiang a, risk hniam emaw, risk sang emaw tiin a thliar hrang thin.
Heng test chungchanga thutlukna siam hi i enkawltu oncologist-in a siam a ni. Chuvangin hemi chungchanga zawhna i neih chuan i zawt thei ang.
Take-Home Thuchah a ni
- Hnute cancer tam zawk hi thlahtute atanga lo chhuak a ni lo . Kan tar chhoh zel chuan kan genes a inthlak danglam vang a ni thei.
- BRCA genetic testing hi mi zawng zawng tih tur a ni lo . Chhungkaw cancer vei chak tak tan chauh a tha.
- I chhungte hnai tak, i nu emaw, i unaunu emaw, kum 50 an tlin hmaa hnute cancer nei tawh emaw, chhungkaw history-a ovarian cancer emaw, mipa hnute cancer emaw i neih chuan doctor thurawn lak a pawimawh hle.
- Nangmah chauhin genetic testing neih tum ngai suh. Doctor nen sawiho hmasa phawt ang che.
- Genetic test result hi i risk hriatthiamna tur kaihhruaina chauh a ni tih hre reng ang che. 100% dik taka hrilhlawkna a ni lo.
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