I vunah hmun mak tak mai nen i itching em? Extramammary Paget natna (EMPD) a ni thei!

I vunah, a bik takin i groin, armpits, emaw genital area-ah hian sen, scaly, a chang chuan crusty patch i hmu ngai em? Zawi zawiin a lo thang lian niin a lang a, a chang chuan a hnim bawk, ​​a dik em? Okay, chuti a nih chuan vawiin hian chutiang vun natna bik kan sawi dawn a ni. Doctor-te chuan Extramammary Paget’s Disease , a tawi zawngin EMPD an ti a. A tlem deuh a, mahse fimkhur a pawimawh hle.

Extramammary Paget natna (EMPD) hi eng nge ni?

A awlsam zawngin EMPD hi vun natna hmuh tur awm lo tak a ni. A chang chuan cancer chi dang nen pawh a inzawm thei bawk. Mahse chutiang chu a ni reng reng lo. I vun a sen, a hring emaw, a hring emaw a lo lian a, a lian zawk tihna a ni. A châng chuan natna a lo chhuah hnu kum tam tak chu hriat lohvin a awm thei bawk.

Kum zabi 19-naa British doctor thiam tak Sir James Paget hming chawia "Paget's Disease" tih a ni. A hming hi cancer chi dang engemaw zatah pawh hman a ni tawh a, hei hi pathology lama a thawhhlawk vang a ni. "Extramammary" tih thumal hi "hnute pawn lam" tihna a ni. Hei hi Paget-a hnute natna nen hian inthlau tur a ni lo.

Extramammary Paget’s Disease vei zinga 7% leh 40% inkar chuan cancer bulpui an nei thei niin an chhut . Mahse, a hmaa ka sawi tawh ang khan EMPD hi natna dang chhinchhiahna a ni ngai lo. Enkawl hmasak hian i natna lan chhuah dan a tihziaawm thei a, cancer hnuaia awmte pawh a hriat theih nan a pui thei bawk.

EMPD chi hrang hrangte chu engte nge ni?

EMPD hi chi hnih a awm a, chungte chu:

1. Primary EMPD: Hei hi vun natna a ni a, amah chauha lo awm a ni. A chhan dang awm lovin vunah a intan thin.

2. Secondary EMPD: Hei hi taksa hmun danga cancer hnuaia awm vang a ni.

Tute nge EMPD vei tam zawk?

Tu pawhin EMPD hi an vei thei a, mahse a hnuaia pawl hrang hrangah hian a tam zawk:

• Kum 50 leh 80 inkar te .
• Hmeichhia zingah a awm fo thin .
• Asian mipa zingah pawh hmuh tur a awm .
• Mi var te.

Mahse hei hi thil awm lo tak a ni tih hriat reng a pawimawh.

Engvangin nge he EMPD hi a lo awm?

Eng thilin nge primary EMPD hi a thlen?

Dik tak chuan doctor-te chuan primary EMPD thlentu hi eng nge ni tih chiang takin an la hre lo. Kan taksaa cell chi hrang hrangah a intan thei niin an ring. Heng cell chi hrang hrangte hi:

• Apocrine gland duct cells: Hengte hi thawmhnaw hrui (sweat glands) an ni a, sam hnah (hair follicles) bulah an awm a.
• Keratinocyte stem cells: Hei hi vun siamthatna atana puitu cell te an ni.
• Toker cells: Hengte hi hnute leh vaginal opening vel vun (`vulvar tissue`)-a awm cell te an ni.

Eng thilin nge secondary EMPD hi a thlen?

Secondary EMPD hi taksa hmun danga cancer vang a ni. EMPD vei hmun thuma ṭhena hmun khat vel chu rectal cancer vang nia sawi a ni. Tin, cancer chi dang, secondary EMPD thlen thei a awm bawk:

• Anal cancer a ni
• Bladder cancer a ni
• Cervical cancer a ni
• Ovarian cancer a ni
• Prostate cancer a ni
• Uterine cancer a ni

EMPD natna lan chhuah dante chu engte nge ni?

EMPD chhinchhiahna ber chu vun rawng a ni a , eczema ang mai a ni . Research atanga a lan dan chuan EMPD vei zinga 65% vel ah chuan vulva vel ah a awm a, 20% vel ah chuan anus vel ah a awm bawk.

I vunah hian heng mizia te hi i hmu thei ang:

• A hnah (`Crusty`) ang maiin .
• A rawn sen (`Red`) .
• Scaly a ni

Spot te hi a lian zauh zauh a, a sir pawh a mumal lo thei bawk. EMPD a kal zel chuan ulcer thuk tak emaw nodules emaw a lo awm thei a ni. A lan chhuah dan dangte chu:

• Burning sensation a awm
• Vun a sen a , a thinrim hle bawk .
• Itchy a ni
• Natna emaw, tender emaw
• Vun a hring (edema) a ni

EMPD hi i thawmhnaw (a bik takin apocrine skin glands) awmna hmunah a awm tlangpui. Vaginal opening vel ah hmuh tur a awm tam ber. Heng hmunah te pawh a awm thei bawk:

• Anus chhehvel (`Anus`) .
• Penis a ni
• Perineum a ni
• Scrotum tih hi a ni

A tlem hle a, EMPD hi taksa peng dangah pawh hmuh tur a awm a, chungte chu:

• Pum chhunga awm
• Armpit a ni
• Bellybutton a ni
• Buttocks a ni
• Beng, mitmeng, hmai emaw lu vun emaw
• A rilru hnuai lam
• Khup emaw, kekawr emaw

Extramammary Paget natna vei zinga 10% vel chuan symptoms an nei lo tih hriat a pawimawh .

Engtin nge he EMPD natna hi hriat chhuah a nih?

A hmasain doctor chuan i natna lan chhuah dan a zawt ang che a, taksa enfiahna a nei ang. EMPD i nei nia an rinhlelh chuan:Skin biopsy tih a ni. Biopsy tih hian i vun sample tlemte lak a, microscope hmanga enfiah a ni.

Microscope hmanga a en hian pathologist chuan cell bik, lian leh pangngai lo, "Paget cells" an tih chu a zawng thin. Heng cell te hi chemical chi hrang hrang (immunohistochemistry) laka an thil tih dan enin an hrechhuak bawk.

Engtin nge EMPD hmanga cancer i vei tih i hriat theih ang?

EMPD i vei tih i hriat hnuah i doctor chuan test dang engemaw zat a nei ang a, underlying cancer a awm leh awm loh a enfiah ang. Heng test-ah hian:

• Ultrasound hmanga scan (`Ultrasound`) hmanga tih a ni.
• Hnute enfiah (mammogram) .
• Pap hnawih a ni
• Colonoscopy emaw proctoscopy emaw hmanga enfiah a ni
• CT scan a ni
• Cystoscopy (bladder enfiahna) 1.1.
• Prostate enfiah a ni
• Retrograde pyelogram (kal leh zun kawng enfiahna) .
• Ultrasound emaw needle biopsy hmanga lymph node te tih a ni
• Upper endoscopy (ril, chaw kawng, leh pum enfiah) .

EMPD enkawlna tur engte nge ni?

Doctor-te chuan extramammary Paget natna hi operation hmangin an enkawl tlangpui.

• Mohs surgery: Hetiang procedure-ah hian surgeon chuan vun natna chu layer khatin a paih chhuak a, a chhehvel vun hrisel chu a humhim thei a ni.
• Wide local excision: Hetiang tih danah hian surgeon chuan EMPD awmna hmun chu a chhehvela tissue hrisel thenkhat nen a paih chhuak thin. Chumi hnuah chuan hliam kilte chu sutured a ni.

A châng chuan surgeon-te chuan vun leh tissue dangte hmun zau tak an paih chhuah a ngai ṭhin. Vulva chhehvela EMPD vei thenkhat chu vulva thenkhat emaw, a zawng zawng emaw lakchhuah a ngai mai thei (a `vulvectomy`).

Hei hi han ngaihtuah teh: Hriselna dang emaw, hriselna \ha lo emaw avanga operation i neih theih loh chuan i doctor chuan enkawlna dang a rawn rawt thei ang che:

• Immunotherapy hmanga enkawl a ni
• Laser hmanga vun rawn lang leh
• Photodynamic therapy (PDT) hmanga enkawl a ni.
• Radiation hmanga enkawlna a ni
• Cancer enkawlna atana hman tur damdawi (cytotoxic drugs) .

A pawimawh ber chu cancer hnuaia awm a nih chuan a hranpaa enkawl a ngai bawk.

EMPD vei theihna tihtlem dan tur a awm em?

Vanduaithlak takin EMPD vei theihna tur tihziaawmna tur engmah kan nei lo.

EMPD vei hian eng ang hmalam hun nge a beisei theih ang?

EMPD enkawl hnuah doctor nen follow-up visit neih a ngai dawn a ni. Hei hi EMPD awmna hmunah a innghat ang. EMPD hi a hmaa enkawl tawhna hmunah emaw, a chhehvelah emaw a lo lang leh fo thin. Chuvang chuan doctor thupek zawm chhunzawm zel a pawimawh hle.

Extramammary Paget natna hi a tlem hle a, taksa peng dangah a darh (metastasis) a ni. Mahse, a chang chuan lymph node emaw, taksa peng dang emaw-ah a darh thei a ni. I doctor chuan i case-a thil awm thei chu a sawifiah thei ber ang.

EMPD hi a dam hnuah a lo kir leh thei ang em?

Ni e, EMPD hi enkawl leh dam hnuah pawh kum tam tak hnuah pawh a lo lang leh thei a ni. A chang chuan kum 15 chuang hnuah a lo let leh thei bawk. Chuvangin doctor-te chuan hun rei tak enkawl leh checkup reng reng an rawt a ni.

EMPD ka neih chuan engtin nge ka in enkawl ang?

I tih theih tha ber chu i doctor hnenah regular follow-up appointment neihpui zel hi a ni. I doctor chuan EMPD lo kir lehna chhinchhiahna a hmuh chuan enkawl tan nghal thei a ni.

Engtikah nge Doctor ka hmuh ang?

EMPD chhinchhiahna thar i hmuh chuan, emaw, natna lan chhuahna thar i neih chuan doctor pan nghal rawh.

I taksa hmun sensitive tak, i genitals ang chiah-a vun rawng emaw, lump emaw i hmuh hian hlauhna, mualphona leh lungawi lohna i neih hi thil pangngai a ni. He natna hi Extramammary Paget’s Disease (EMPD) tia koh a ni a, a chang chuan vun natna dang nen pawh a inthlau thei a, chuvangin a dik taka hriat theih nan hun rei tak a ngai thei a ni. Cancer hnuaia awm a awm chuan EMPD hi a na zawk thei.

Mahse, thu lawmawm tak chu EMPD vei tam zawk hi enkawl hnuah nun pangngai, nun pumhlum an hmang a ni. EMPD hi operation hmanga enkawl a ni tlangpui. Cancer hnuaia awm a nih chuan chu pawh chu enkawl a ngai dawn a ni. Extramammary Paget’s Disease hi a lo lang leh thei a, chuvangin doctor hnena checkup neih fo hian a lo let leh a nih chuan a hmain a hriat theih nan a pui thei a ni.

I hriat reng tur pawimawh ber berte (Take-Home Message) .

• EMPD hi vun natna hmuh tur awm lo tak a ni a, cancer nen pawh a inzawm thei.
• Vun sen, a hring, a hring emaw, a sang emaw, a bik takin, mipat hmeichhiatna hmun, kawrfual, emaw, hnute vel emaw vel chu ngaihven rawh. A lan chhuah dan chu hnim hring, kang, leh natna te a ni thei.
• Hetiang chhinchhiahna i hmuh chuan , zak leh hlau suh, mahse doctor pan nghal rawh.
• EMPD hi vun biopsy hmanga hmuhchhuah a ni.
• Surgery hi a enkawl dan tlangpui a ni.
• Medical checkup chhunzawm zel a pawimawh a, EMPD hi a lo lang leh thei a ni.
• Ngaihtuah buai suh, EMPD vei tam zawk hi enkawl hnuah an dam tha hle. A pawimawh ber chu natna hi hriat hmasak a, enkawlna dik tak neih hi a ni.

Hemi chungchanga zawhna dang i neih chuan i doctor nen inbia ang che. I tana tha tur thurawn a pe thei che a ni.

` Extramammary Paget’s Disease, EMPD, vun natna, vun cancer, Paget cells, vun hring, itching, vulva, perianal area, vun natna, Mohs surgery