I chau reng reng em? I pale a, vun rawng sen i nei em? A nih loh leh in chhungkuaa mi tu emaw hian thisen natna (hereditary blood disease) a nei em? Hetiang hunah hian i doctor chuan thisen test bik neih a rawt thei che a ni. Chutiang thisen test pawimawh tak, special tak, tunlaia kan sawi tak pakhat chu Hemoglobin Electrophoresis tih a ni. A hming hi a buaithlak deuhin a lang thei a, mahse a tih dan chu a awlsam hle. Eng nge a nih, engvangin nge tih a nih, eng nge kan zir theih ang tih i lo en ang u.
Hemoglobin Electrophoresis tih hi eng nge ni?
A awlsam zawngin, Hemoglobin Electrophoresis hi special lab test a ni a, i thisen sen chhunga hemoglobin chi hrang hrang, leh a chhunga hemoglobin awm zat te a en thin.
Okay, tunah chuan, "He hemoglobin hi eng nge ni?" I taksa chhunga thisen sen (red blood cells) te hi delivery truck te tak te ang maiin han ngaihtuah teh. Tichuan hemoglobin chu chu truck chhunga thu ‘delivery man’ chu a ni a, lung atanga oxygen packet la chhuakin taksa chhunga cell dang zawng zawngah a sem chhuak thin He ‘delivery man’ hian hna a thawh that hunah chauh kan taksa peng tinah oxygen tling kan hmu thei ang.
Mahse a chang chuan, genetic reasons avang hian he protein hemoglobin an tih hian inthlak danglamna emaw, chhiatna emaw engemaw zat a tawk thin. Tichuan he ‘delivery man’ hian tlem a danglam deuhin a awm tan ta a ni. He hemoglobin chhiat avang hian thisen sen (red blood cells) pianzia a danglam thei a, a chhe thuai thei a, taksain oxygen a mamawh zat dik tak a dawng lo thei bawk. He Hemoglobin Electrophoresis test hi kan ti a, chutiang hemoglobin chi hrang hrang, chhia chu a awm em tih chiang takin kan hre thei a ni.
Hei hi hemoglobin test pangngai nen hian eng nge a danglamna?
Hei hi mi tam tak tibuaitu a ni. FBC (Full Blood Count) report i en chuan Hemoglobin (Hb) tih value a awm bawk.
- General hemoglobin test (FBC-a hmuh): Hei hian i thisena hemoglobin awm zawng zawng a tehna chauh a ni. Kan entirnan, i taksaah ‘delivery men’ engzat nge i neih tih check ang mai a ni.
- Hemoglobin Electrophoresis Test: Hei hi test thuk zawk a ni. I thisena hemoglobin chi hrang hrang leh chi hrang hrang awm zat a en thin . 'Delivery mipa' engzat nge awm tih en mai ni lovin , "tha" an awm em, "a danglam deuh" an awm em tih te, leh "defective" an awm em tih te , a awm a nih chuan engzat nge awm tih pawh en ang mai a ni.
He test hi thisen lama natna inherited, sickle cell anemia leh thalassemia te hriat theihna atan a pawimawh hle.
Hemoglobin chi hrang hrang hi han sawi ila.
He test hian a zawn ber hemoglobin chi hrang hrang a awm. Hengte hi hriatthiam awlsam zawk nan a hnuaia table hi en la.
| Hemoglobin chi khat a ni | A tawi zawngin sawi ila, hei hi eng nge ni... |
|---|---|
| Hemoglobin A (HgbA) a awm bawk. | Hei hi puitling hrisel thisena awm tam ber, "normal" chi a ni. Puitling hrisel takah chuan hemoglobin zawng zawng 95% aia tam a ni. |
| Hemoglobin F (HgbF) hi a awm a. | Hei hi "fetal hemoglobin" an ti a. A hming ang bawkin hei hi nausen leh nausen piang tharte hemoglobin chi khat ber a ni. Naute a lo puitlin chuan HgbF a tlahniam a, HgbA a pung bawk. Puitlingah chuan hei hi a sang hle a, chu chu damdawi lam dinhmun thenkhat chhinchhiahna a ni thei. |
| Hemoglobin S (HgbS) a awm bawk. | Hei hi sickle cell anemia thlentu hemoglobin chhia chi khat a ni . Chutiang a nih chuan thisen sen (red blood cells) te chu an pianzia zungbun pangngai ni lovin, sickle ang maiin an awm a, thisen kalna kawngah an tang thei a ni. |
| Hemoglobin C (HgbC) a awm a ni. | Hei hi hemoglobin chhia chi dang a ni. Hei hian thisen sen (red blood cells) chu a hun hmain a ti chhe thei a, chu chuan thisen tlakchhamna (thisenah thisen tlakchhamna) a thlen thei a ni. |
Engtin nge he test atan hian thisen i lak theih ang? Hlauh tur thil a ni em?
Ni miah lo. Hei hi thisen test pangngai ang mai a ni. Thisen lak dan hi kum leh mamawh dan azirin a inang lo deuh thei.
| Thisen lak dan | Hrilhfiahna |
|---|---|
| Venous thisen lak chhuah | Hei hi puitling leh naupang kum upa zawkte tana hmanraw hman tlanglawn ber a ni. I elbow crook-a vein pakhatah needle te tak te dahin thisen tlem te te chu lakchhuah a ni. Hriselna tlemte i nei thei a, rulhut seh ang maiin, mahse second tlemte chauh a daih. |
| Finger stick a ni | Hetiang hmanrua hi naupang tê tê emaw, thisen tlemte chauh mamawh hunah emaw hman a ni. Thisen tlemte chu kut zungtang tip chu zungbun te tak te hmanga chilhin an la khawm thin. |
| Heel stick a ni | Hei hi naute piang thar tan tih a ni . Naute pian atanga darkar 48 chhungin an kekawrteah hian needle te tak te an chil a, thisen tla tlemte chu special card-ah an khawn khawm thin. Hei hi Sri Lanka rama naute piang thar zawng zawng deuhthaw chunga test neih thin ``newborn screening`` series-a tel a ni. Hei hian a hmaa hmuhchhuah a nih chuan natna khirh tak, mahse enkawl theih Sickle Cell Anemia ang chi te a hmuchhuak thei a ni. Naute tihnat tur ngaihtuah buai suh, hei hi nuin naute a la chelh lai hian tih theih a ni. |
Lab-a he thisen sample hi engtin nge a awm?
I thisen sample chu lab-a a kal chuan chuta technician-te chuan tih dan bik an zawm thin.
Hemoglobin chi hrang hrangte hi a rit zawng inang lo leh chakna hrang hranga tlan thei mi ang an ni tih han ngaihtuah teh.
1. Pakhatnaah chuan i thisen sen (red blood cells) atang hian hemoglobin chu a inthen a.
2. He hemoglobin mixture hi gel emaw paper strip bik emaw-ah dah a ni.
3. Tunah chuan hei hi electric current pek a ni ta.
4. Electric hman a nih chuan hemoglobin chi hrang hrang hi he gel hmang hian hmalam pan zelin speed hrang hrangin an kal a , a rit leh electric charge a zirin.Running intlansiak ang bawkin tlan chak zawkte chuan hma an hruai a, slow zawkte chu an hnufual ta a ni.
5. Hun engemaw chen hnuah heng hemoglobin chi hrang hrangte hi rawng hrang hranga siam angin an lo lang ta a ni .
6. A tawp berah chuan lab staff te chuan i band pattern chu mi hrisel tak pattern pangngai nen an khaikhin a. Hei hian i thisena hemoglobin chi hrang hrang awm chu chiang takin a hre thei a, a zat chu a pangngai leh pangngai lo a nih leh nih loh a hre thei bawk.
Ka report hian eng nge a awmzia?
Test atanga ni engemaw zat chhungin report i dawng ang. Hemoglobin chi hrang hrang percentage leh value te a tarlang ang. Entirnan, HgbS emaw HgbC emaw a awm tih a lantir chuan Sickle Cell Disease emaw, a ang chi emaw chhinchhiahna a ni thei. Puitlingah HgbF level a sang a nih chuan Thalassemia ang chi natna chhinchhiahna a ni thei.
Mahse thil pawimawh tak pakhat chu hre reng ang che. He report-a number leh letter hmang hian nangmah ngeiin thutlukna siam suh la, internet hmangin diagnosis siam suh. I rilruah ṭul lova hlauhna a thlen thei a ni.
He report awmzia dik tak hi i doctor chauhvin a hrilhfiah thei ang, i natna lan chhuah dan leh test dangte nena inzawm a ni. Chuvangin report i dawn veleh a ordertu doctor nen inhmuhkhawm la, sawiho rawh.
I naute report-ah thil danglam tak a lan chuan nu leh pate chuan hlauhna leh lungkhamna an neih hi thil pangngai a ni. Mahse, lungngai suh. I naute mamawh enkawlna leh enkawlna chu a hmaa tan theihna hun remchang i nei tihna a ni. I doctor chuan i mamawh thurawn zawng zawng a pe ang che.
Take-Home Thuchah a ni
- Hemoglobin Electrophoresis hi test bik a ni a, thisen a hemoglobin awm zat chauh ni lovin, a chi hrang hrangte pawh a teh thei bawk .
- Hei hi thisen natna chi hrang hrang, sickle cell anemia leh thalassemia te hriatchhuahna kawngah a pui hle.
- He test atan hian i thisen lak tir hi a awlsam hle a, a him hle bawk. Hlauhna tur a awm lo.
- A pawimawh ber chu: Report hi nangmah ngeiin hriatthiam tum suh. I doctor hnenah entir fo la, a chipchiar zawkin zawt rawh.
- Report pangngai lo chu khawvel tawpna a ni lo. Diagnosis dik tak leh enkawlna tul tak neih theihna tura zinkawng hmasa ber chauh a ni.
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