Tun hnaiah i chhungkuaa tar pakhat, i nu emaw, i pa emaw, i pi emaw, i pi emaw pawh ni se, thil tenawm tak tak a theihnghilh tih i hmuchhuak em? I chabi awmna hmun, mi hming, hna i tih tur ang chi thilte... A nihna takah chuan hetiang theihnghilh hi kan tar chhoh zel hian a thleng fo thin. Mahse he dinhmun hi a zual zauh zauh a, i hriatrengna a chak lo lutuk a, nitin hna pawh i thawk thei lo a nih chuan Alzheimer’s ang natna chhinchhiahna hmasa ber a ni thei. Chuti a nih chuan he thil hi a hma, awlsam taka hriat theih dan awm ta se engtiang chiahin nge a hlut ang? Chu chu vawiina he thuziaka kan sawi tum chu a ni a, beiseina nasa tak min pe a ni.
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He thisen test thar hi eng nge ni?
Tun hnaia zirchianna pakhatah chuan thisen test thar an hmuchhuak a, chu chuan Alzheimer natna chhinchhiahna a hmuchhuak thei a ni. Hemi chungchanga thil danglam bik chu he thisen test awlsam tak hi tuna hman mek, hrehawm leh buaithlak tak, spinal tap ang chiah hian a dik a ni.
A awlsam zawngin, he thisen test hian kan thisena protein bik p-tau217 tih chu a teh a ni. Researcher-te chuan mi pakhatin a thisenah he p-tau217 protein level nasa taka a san chuan Alzheimer natna nena inzawm tlat protein dang pahnih: amyloid beta leh tau -a inthlak danglamna tilangtu chak tak a ni tih an hmuchhuak. Hengte hi Alzheimer natna a lo awm huna thluaka protein lo awm khawm berte an ni.
He thisen test thar hian 97% thleng a dik tih a hmuchhuak a, hei hi rintlak tak a ni. Tin, he zirchiannaa tel zinga 20% chauhvin natna hi finfiah nan test dang neih belh an mamawh bawk.
Hei hi tuna test hman mek nen engtin nge a danglam?
Tuna Alzheimer natna dik taka hriat theihna atana hmanraw tha ber berte hi a buaithlak deuh a ni. He thisen test thar nen hian eng nge an nih leh an danglamna hi han thlir ila.
| Test dan tur | Hrilhfiahna | A that lohna leh harsatna a awm |
|---|---|---|
| Spinal Tap a ni | Spinal cord kaltlangin needle bik dahin cerebrospinal fluid, thluak leh spinal cord vel tui tlemte lakchhuah a ni. | A na thei a, hlauhawmna engemaw zat a awm a, damdawi ina awm a ngai bawk a, mi tam takin hei hi an hlau hle. |
| PET Scan a ni | Scanner sensitive tak, specialized tak chuan thluaka amyloid leh tau protein awmte thlalak a la thin. | A man a to hle mai. Heng facility te hi damdawi in zawng zawngah hman theih a ni lo. Hmun hla taka chengte tan chuan hmuh a har khawp mai. |
| Thisen test thar p-tau217 | Arm chhunga vein atanga thisen sample lak dan pangngai hmanga p-tau217 protein level test. | A awlsam hle a, risk a hniam hle a, hmanraw dang nena khaikhin chuan a man a tlawm hle a, khawi hmunah pawh awlsam takin tih theih a ni. |
He zirchiannaa thisen test hman hi ram dangah 200 leh 500 inkar velin lak theih a ni an ti. Hei hi Sri Lanka-ah chuan sum tam tak ni mah se, PET scan ang chi test nen khaikhin chuan he senso hi a tlem hle a, dollar maktaduai tam tak sen a ngai a ni.
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Khawvel hriat hlawh medical journal JAMA Neurology-a tihchhuah he zirchianna hian p-tau217 thisen test hi hriatrengna lama harsatna awmte enfiahna hmanraw hmasa ber a ni thei tih a tarlang
Hetiang hian han ngaihtuah teh. Miin hriatrengna lama harsatna a neih theih a rinhlelh chuan he thisen test awlsam tak hmang hian a tan thei a ni. Symptoms an nei tih clue a pek chauhvin test man to zawk, complex zawkah an kal thei ang. Hei hian damlo leh doctor-te hun leh sum tam tak a humhim thei a ni.
A pawimawh ber chu hetianga natna hi a hmaa hriatchhuah a nih chuan thluaka amyloid protein target-a enkawlna thar chu tan thuai theih a ni. Natna eng pawh enkawl tan a nih chuan a rah a tha zawk thin.
General forgetfulness leh Alzheimer natna te a ni
Alzheimer’s hi dementia chi khat, a nih loh leh hriatna tlahniam (cognitive decline) chi khat a ni. Kum upa lam kan lo upat deuh deuh hian hriatrengna leh ngaihtuahnaah inthlak danglamna tenau tak tak kan tawng thin hi thil pangngai a ni. Mahse, heng inthlak danglamna te hi nitin hna thawh harsat khawpa nasat a nih chuan dementia chhinchhiahna a ni thei.
Entirnan, i chabi i dahna hmun theihnghilh a, rei vak lo hnuah hriatreng leh chu thil pakhat a ni. Mahse, chabi chu eng nge a nih leh eng atan nge a hman tih i theihnghilh vek chuan chu chu thil pawi tak a ni. Chutih hunah chuan damdawi lam thurawn kan zawng tur a ni.
Chuti a nih chuan tunah hian he thisen test hi kan ti thei ang em?
Hei hi zawhna pawimawh ber a ni. He test hi ram thenkhatah chuan sumdawnna atana hman theih ni tawh mah se, a bul tanna a la ni. Zirchiangtute ngei pawhin heng result te hi mipui zahawm tak, chu chu natna lanchhuahna nei lote tan engtin nge a hman theih tih finfiah nan zirchianna neih belh a ngai niin an sawi.
He test hi Sri Lanka-ah chuan a la awm vak lo. Mahse khawvel hmun hrang hrangah damdawi lam kawngah beiseina nasa tak a siam a ni. Nakinah chuan keini pawhin awlsam taka hetiang test awlsam leh man tlawm tak tak kan tih theih hun tur ni a lo thleng dawn a ni.
A pawimawh ber chu, nangmah emaw, i chhungte zingah emaw, hriatrengna chungchangah rinhlelhna emaw, harsatna emaw i neih chuan internet-a i thil chhiarte hmangin nangmah ngeiin thutlukna siam suh. I chhungkaw doctor (physician) hmu la, hemi chungchang hi sawipui ngei ang che. Eng test nge i mamawh tih leh eng step nge i tih tur tih chu i symptoms a zirin kaihhruaina chiang tak a pe ang che.
Take-Home Thuchah a ni
- Alzheimer natna hriat hmasak theihna tura thutiam nei thei tur thisen test thar, awlsam tak chungchangah zirchianna hlawhtling tak neih mek a ni.
- He test hian thisenah protein p-tau217 an tih chu a teh a, tuna test man to leh buaithlak tak tak hman mek ang chiah hian a dik tih hmuhchhuah a ni.
- Hei hi nakin lawkah chuan natna hmuhchhuah hmasakna atana screening test atan a pawimawh hle thei a ni.
- Nangmah emaw, i hnaih ber emaw hian hriatrengna lama harsatna lian tak i neih chuan a tha ber leh tih tur awm chhun chu doctor thiam tak hnen atanga thurawn lak nghal mai hi a ni.
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