Kan taksaah hian kan hriat lohva virus chi engzat nge awm? JC virus hi chutiang zinga mi a ni. Dik tak chuan he virus hi khawvel puitling zinga a chanve aia tam taksaah a cheng a ni. Mahse mak tak mai chu, mi tam zawk tan harsatna leh buaina a thlen lo. Chuvangin, vawiinah hian hei hi eng nge a nih tak tak tih te, engtikah nge buaina a lo nih dan te, kan hlau tur nge tih te chipchiar takin kan sawi dawn a ni.
JC virus hi eng nge ni tak tak?
A awlsam zawngin sawi ila, JC virus hi virus tlanglawn tak a ni. Kum 1971 khan hmuhchhuah hmasak ber a ni a, Doctor pakhat chuan he hri hi mipa pakhat, cancer natna vei, Hodgkin’s lymphoma vei thluak ah a hmuchhuak a. He virus hi damlo hming hmasa (John Cunningham) atanga an vuah a ni.
Mahse mithiamte chuan engtin nge mi pakhat atanga mi dangah a darh tih an la hre chiang lo. Amaherawhchu, mi tam tak chuan he hri hi kan naupan lai hian kan taksaah tui bawlhhlawh emaw, ei tur emaw hmangin a lut niin an ngai. A chhunga a luh tawh chuan kan zun kawng, ruhro, tonsils, emaw thluaka kum tam tak chhung chu a muhil thei a, harsatna a thlen lo. Chuvang chuan mi tam takin hri kai an ni tih pawh an hre lo.
Chuti a nih chuan he thil atang hian tu nge hlauhawm?
Hetah hian a pawimawh ber. I immune system a tha a, a chak chhung chuan JC virus hian a tibuai lovang che. Mut ang mai a ni.
Mahse, eng emaw chhan vanga mi pakhat taksa hriselna a chak lo hle a nih chuan , chu virus muhil chu a harh nghal a, a thawk tan ta a ni.
Hetianga virus hi a thawkrim chuan thluaka natna khirh tak tak, Progressive Multifocal Leukoencephalopathy , emaw PML , a thlen thei a ni.
PML chu eng nge ni?
Hei hian kan nerve cells vel a protective covering chu a tichhia a ni . Electric wire-a plastic khuhna chu a hmin ang mai a ni. Hei hian nerve hmanga thuchah thawn dan chu a tibuai vek a ni. Hei hian chak lohna nghet tak a thlen thei a , a chang chuan thihna pawh a thlen thei bawk .
PML vei theihna sang ber chu:
- HIV/AIDS vei te tan.
- Hodgkin natna a ni), cancer natna vei, leukemia leh lymphoma te.
- Multiple Sclerosis (MS) , Rheumatoid Arthritis , emaw, taksa peng thlak hnua immune-suppressing damdawi chi hrang hrang ei thinte tan
PML natna lan chhuah dante chu engte nge ni?
Heng symptoms te hi a intan thuai tlangpui a, hun kal zelah a zual zel bawk. Thluak chhiatna hmun a zirin symptoms a inang lo thei. Mahse, hengte hi a lan chhuah dan tlangpui a ni.
| Symptom a ni | Hrilhfiahna |
|---|---|
| Clumsiness a ni | Thil tihfel harsa, kal laia tlu, kut atanga tlu te ang chi thil te. |
| Chak lohna a zual zel | Kut, ke emaw, taksa peng khat emawa chak lohna chu zawi zawiin a pung zel a. |
| Mihring nihna inthlak danglamna | Thinrimna rang tak, buaina, leh hriatrengna hloh ang chi inthlak danglamna. |
| Thusawi buaithlak | Thumal a inzawm khawm a, ka sawi duh chu ka sawi chiang thei lo. |
| Mit hmuhna lama harsatna a awm | Vision a fiah lo va, thil pahnih vawi khata hmuh ang chi harsatna a awm bawk. |
Engtin chiah nge hei hi i diagnose?
A hmasa berin JC virus i vei em tih test i nei thei ang. Hei hian thisen test emaw tissue sample emaw lak a huam a ni . Hei hi i immune system titawp thei damdawi i ei a nih chuan a pawimawh hle .
Mahse, i doctor-in PML i vei nia a rinhlelh chuan test dan a danglam.
1. MRI scan: I test hmasa ber tur chu MRI (Magnetic Resonance Imaging) scan a ni. Hei hian magnet chak tak tak leh radio wave hmangin i thluak thlalak chipchiar tak tak a la a, PML ang chi thluak tissue-a pattern awmte a zawng bawk.
2. Spinal Tap : A dawtah chuan i doctor chuan spinal tap (lumbar puncture) tih a rel mai thei . Ngaihtuah buai suh, hei hian needle te tak te lak a, i hnungzang hnuai lam atanga spinal fluid tlemte lak a huam a ni. He fluid hi JC virus awm leh awm loh test a ni. He fluid-ah hian JC virus hmuh a nih chuan PML a awm tih a nemnghet a ni.
3. Brain Biopsy: A chunga test te hi a la chiang lo a nih chuan thluak atanga tissue te tak te te chu test (biopsy) atan lak a ngai mai thei.
Natna thenkhat enkawlna atana hman damdawi leh JC virus inzawmna
Multiple Sclerosis (MS) leh Crohn natna te a ni
Multiple Sclerosis (MS) leh Crohn’s Disease (entir nan, Natalizumab, Dimethyl fumarate, Fingolimod, Ocrelizumab ) te ang chi natna enkawlna atana hman thin damdawi thenkhat chu PML nen a inzawm tih hmuhchhuah a ni.
Chuvangin, he damdawi chi hi i tan hmain i doctor chuan JC virus i nei em tih a enfiah ngei ang. He damdawi hi hripui i vei pawhin i ei thei mai thei a, mahse thutlukna i siam hmain i doctor nen a hlauhawmna leh a thatna te i sawipui hmasa phawt tur a ni.
HIV/AIDS vei vang a ni
Tunlai damdawi thenkhat HIV/AIDS vei te hnena pek thin hian taksa hriselna tichak turin a pui thin. Hei hian JC virus atanga PML lo awm tur venna kawngah nasa takin a pui a ni. Chuvang chuan tun hnaiah HIV/AIDS vei zingah PML vei an tlahniam nasa hle a ni.
PML enkawl dan tur chu engte nge ni?
Tunah hian PML tihdam kim theihna tur damdawi bik pawm a la awm lo a, scientist-te chuan hei hi an la zirchiang mek a ni.
Tuna enkawl dan tha ber chu kan taksa hriselna (immune system)-in hri hi a din thar leh a, a mah chauha a do let theihna tura puih hi a ni. Entîr nân, miin a taksa chakna tichhe thei damdawi a ei a nih chuan, an doctor chuan chu damdawi chu tihtawp emaw, thlak emaw chu a rel thei a ni.
Take-Home Thuchah a ni
- JC virus hi virus tlanglawn tak a ni a, mi tam zawk tan chuan a hlauhawm lo. Chuvangin tul lovah hlau suh.
- Hei atanga hlauhawm tak tak awm chhun chu immune system chak lo tak tak nei te tan a ni a, thluaka natna khirh tak PML an tih chu an nei thei a ni.
- Thil danglam tak, chak lohna danglam tak, kal leh tawng harsa, emaw, mize inthlak danglam nghal emaw i neih chuan, a bik takin i taksa hriselna tichhe thei damdawi i ei a nih chuan doctor pan nghal rawh.
- MS leh Crohn’s ang chi natna damdawi thenkhat i ei tan hmain JC virus leh PML hlauhawmna chungchang hi i doctor nen sawi hmasa phawt ang che.
- Hemi chungchangah hian zawhna emaw rinhlelhna emaw i neih chuan a tha ber chu i doctor nen chiang taka sawipui a, hriattirna dawng tur a ni.
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