Thisen zam i nei nghal em, a nih loh leh naupai laiin harsatna engemaw zat i nei a, doctor-in thisen test a nei em? Report-a ‘Lupus Anticoagulant positive’ tih a nih khan i lungngai em? ‘Lupus’ tih thumal i hmuh khan hei hi lupus a ni tih i ngaihtuah khan i hlau em? He hming hi a takah chuan a buaithlak deuh. Chuvang chuan mi tam takin hemi chungchangah hian inhriatthiam lohna an nei thin. Hemi chungchanga harsatna awm zawng zawng hi vawiin hian i tifai vek ang u.
Lupus Anticoagulant hi eng nge ni tak tak?
A awlsam zawngin sawi ila, hei hi kan thisena awm thei antibody chi khat a ni.
Kan taksa invenna (immune system) hi ram venghimtu sipai angin han ngaihtuah teh. Pawn lam atanga natna hrik emaw thil tha lo emaw taksa chhunga a luh chuan he sipaite hian chu hmelma chu an hre chiang a, chu chu tihchhiat tumin sipai bik pawl, antibodies an tih chu an siam chhuak thin. Hei hi thil thleng tlangpui a ni.
Mahse, a chang chuan kan immune system a kal sual thin. Ramdang mi rawn bei ai chuan kan cell hrisel tak takte chu a bei tan ta zawk a ni . Chutiang chuan lupus anticoagulant (LA) hi antibody a ni a, tihsual avanga siam chhuah a ni a, keimahni taksa ngei pawh a tichhe thin.
He LA antibody hi antibody dang pahnih nen hian Antiphospholipid Syndrome (APS) tih hming puin natna a thlen thei a ni. Hei hi autoimmune natna a ni. Chumi ziarang ber chu taksa thisen kalna kawng hrang hranga thisen zam (blood clots) lo awm theihna hi mi pangngai aiin a sang zawk hle a ni.
Chuti a nih chuan engvangin nge hei hi ‘lupus’ an tih? Hei hi lupus natna nen a inang em?
Hei hi mi tam tak buaina leh hlauhthawnna hmun a ni. A hmingah hian ‘lupus’ part awm mahse, a takah chuan lupus hi thil hrang hrang pahnih a ni a, chungte chu Lupus Anti-Coagulant (LA) leh Lupus natna te an ni. He hming hi engtin nge a lo awm tih hi thawnthu ngaihnawm tak a ni.
He antibody hi kum sawm tam tak kalta khan zirchiangtute chuan lupus vei thisen sample an test khan hmuhchhuah a ni. Chuvangin lupus vei tan thil bik niin an ngai a ni.
He antibody awmna thisen sample te hian in vitro-a clot turin a tlangpui aia rei a daih tih an hmuchhuak bawk. ‘Anticoagulant’ tih awmzia chu ‘thisen a veng’ tihna a ni. Chuvangin, ‘lupus anticoagulant’ tiin an vuah a, chu chu ‘lupus vei taksaa thisen zam tikhawlo thei thil’ tihna a ni.
Mahse, chu ngaihdan pahnih chu a hnuah chuan a dik lo tih hmuhchhuah a ni. Dik tak chuan a kalh zawng a ni. He antibody hian taksa chhunga a tih chu thisen zam tihpun a ni a, a venna a ni lo!
He buaina hi tihfel nan a hnuaia table hi en la.
| Thudik | Lupus anticoagulant (LA) hmanga tihdam theih a ni. | Lupus natna (SLE) . |
|---|---|---|
| Nihphung | Thisenah hian antibody tha lo tak tak a awm. | Taksa chhunga taksa peng hrang hrang tichhe thei, autoimmune disease complex tak a ni. |
| Main effect a ni | Thisen zam awm theihna a tipung. | System tam tak a nghawng thei a, chu chu vun, ruhkawr, kal, thinlung leh thluak te hi a ni. |
| Inlaichinna | LA neih hian lupus i nei tihna a ni lo va, mahse lupus vei thenkhat chuan LA an nei thei. | LA hi lupus nena inzawm thei thil hmuhchhuah pakhat chauh a ni. |
Engvangin nge hetiang thil hi kan taksaah a lo thlen?
Hei hi kan immune system hian a tihsual vang a ni. Heng LA antibodies te hian kan cell pawn lam atanga thau chi khat phospholipids an tih nena inzawm protein te chu an bei thin. He attack hian cell te chu a tichhia a, an inzawm khawm a, thisen zam a tipung a ni.
Mithiamte chuan engvangin nge immune system hian a tir atang khan heng antibody dik lo te hi a siam tan tih hi an la chiang tawk lo. Genetic factors, environment influence emaw, hri kai theihna dang emaw vang pawh a ni thei niin an ngai.
LA positive tih awmzia chu eng nge ni? Engtin nge min nghawng ang?
I thisena LA awm hian antiphospholipid syndrome (APS) tih natna i vei theihna a ni tihna a ni. Hetah hian, ‘at risk’."will" tih thumal hi a pawimawh hle. A thleng ngei dawn tihna a ni lo.
LA antibody hi thisenah awm mahse, thisen zam leh harsatna nei lo, dam chhung zawnga hrisel taka awm mi tam tak an awm.
Chuvangin i report-a hei hi i hmuh hian a tul lovah hlau suh. Mahse, i doctor tan chuan hei hi a hriat chian a, a enkawl che a pawimawh hle. Midang aiin thisen zam i vei tam zawk avangin hriat reng a finthlak hle.
Hei hi eng enkawlna nge ni?
He LA antibody hi taksa atanga paih chhuak vek thei damdawi a la awm lo. Mahse a chhiatna tur thunun nan hian enkawlna tha tak tak a awm a, chu chu thisen zam (blood clots) siam hi a ni.
Symptoms i neih loh chuan, thisen zam i la nei lo tihna a nih chuan, i doctor chuan damdawi engmah pe lovin enkawl mai turin a rel mai thei.
Mahse, thisen zam i neih tawh emaw, APS i vei tih hriat chhuah tawh emaw a nih chuan, a enkawlna ber chu anticoagulants emaw thisen tithianghlimtu emaw a ni . Damdawi chi hrang hrang warfarin leh heparin te hi thisen zam a tihziaawm nan an pe thin. A châng chuan, taksa chakna (immune system) chak lutuk tihziaawmna turin damdawi , corticosteroid ang chi pawh an pe bawk.
Heng enkawlna zawng zawng hi i doctor-in a rel a, i dinhmun, kum leh natna dangte ang chi thil tam tak ngaihtuah a ni.
Engtikah nge Doctor ka hmuh ang? Emergency chu eng nge ni?
Hetiang dinhmun nena kan nun hian thil awmdan pangngai leh emergency inthlauhna hriat a pawimawh hle.
| Huntha | Eng nge tih tur |
|---|---|
| Enfiahna tlangpui | Doctor sawi angin check-up turin hun ruatah clinic-ah kal rawh. Damdawi hman dan tur dik leh dik loh leh tihdanglamna dang a awm leh awm loh enfiah turin thisen test an nei ang. |
| Emergency (ETU ah kal nghal rawh) . |
|
Thisen zam a awm tih hriattirna
- Ke (Deep Vein Thrombosis - DVT): Ke pakhatah a hring nghal a, a sen a, a lum a, a na bawk.
- Pulmonary Embolism: Thâwk harsa nghal, rilru na tak (a bik takin thawk laiin), thisen chhuak.
- Stroke: hmai sir khata tla, kut pakhat hloh, tawng harsa.
Heng symptoms zinga pakhat tal a lo lang a nih chuan damdawi in Emergency Treatment Unit (ETU)-ah kal nghal vat rawh .
Take-Home Thuchah a ni
- Lupus anticoagulant (LA) hi lupus tak tak a ni lo. Thisen chhunga antibody chi khat chauh a ni.
- I thisena LA awm hian thisen zam (blood clot) i neih theihna a sang zawk tihna a ni. A thleng ngei dawn tihna a ni lo.
- Report i hmuh hnuah pawh hlauthawng suh. Mahse he thu hi i doctor nen inbia la, a thurawn zawm ngei ang che.
- Enkawlna tum ber chu thisen zam a lo awm loh nan a ni. I doctor chuan i tana enkawlna tha ber tur a ruat ang.
- Thisen zam a awm tih hriattirna (ke na, rilru na, thawk harsa) te chu fimkhur reng tur a ni. Chutiang symptom a lo lan chuan ETU-ah kal nghal rawh.
- I taksa chhunga i hmuh theih loh thilin a tichhe thei che nia i ngaih hian hlauhna leh lungkhamna i neih hi thil pangngai a ni. Hlauhna neia nun ai chuan hriatna leh ngaihtuahna fim tak nen nung rawh. Chu zinkawngah chuan i doctor chuan a pui thei che a ni.
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