Chau leh nunna nei loin i inhria fo em? Hei hi a chhan pakhat chu taksaa thisen tlakchham vang a ni thei a, hei hi damdawi lam hawi chuan thisen tlakchhamna (anemia) an ti a ni. Damdawi lam thil engemaw avanga he thisen tlakchhamna hi a lo awm chuan thisen pek fo a ngai mai thei. Chuvangin, vawiin hian hetiang dinhmun enkawlna atana khawvela damdawi thar tak tak rawn chhuah tawh chungchang kan sawi dawn a ni. Chu damdawi hming chu Reblozyl a ni.
Reblozyl hi eng damdawi nge ni?
Reblozyl hi kum 2019 khan pawm a ni a, a dik tak chuan ``erythroid maturation agents (EMA)'' tih damdawi class-ah a tel a ni. Okay, okay, chu thumal chu a buaithlak deuhin a ri mai thei. A awlsam zawngin sawi ila, he damdawi hian kan ruhro (bone marrow)-a thisen sen (red blood cells) lo awmte chu "puitling" turin a pui a, chu chu cell tha tak, hrisel tak ni turin a pui a ni. He damdawi hi thisen natna thenkhat avanga thisen tlakchhamna (anemia) enkawlna atan hman a ni ber. A bik takin heng natna pahnih nei puitlingte tan: 1.
Beta-thalassemia: Hetiang dinhmun avanga thisen pek fo ngai te. 2.
Myelodysplastic Syndromes (MDS): Hei hi bone
marrow failure tia hriat a ni bawk. Chuvangin Reblozyl hi thisen pek fo ngai te tan pawh pek thin a ni.
Beta-thalassemia leh MDS chungchang tlem han zir belh ila.
Heng natna pahnih hi tlem tal i hriatthiam chuan Reblozyl damdawi hnathawh dan hi hriatthiam a awlsam zawk ang.
- Beta-thalassemia: Kan thisena thisen sen (red blood cells) te hi oxygen phurtu lirthei angin han ngaihtuah teh. He lirtheia oxygen hi protein pakhat hemoglobin ah a load a ni . Beta-thalassemia vei chuan he hemoglobin protein hi a siam chhuak tawk lo. Chuvangin taksa chhunga cell te hian an mamawh oxygen an hmu lo. Chuvangin hah reng leh vun rawng hring (paleness) ang chi symptoms a awm thin.
- Myelodysplastic syndrome (MDS): Hei hi cancer chi khat a ni a, ruhro atanga intan a ni. Kan thisen cell (red cells, white cells, leh platelets) siamtu factory chu bone marrow hi a ni. MDS vei miah chuan he factory siamchhuah hi a tibuai a ni. Chumi awmzia chu thisen cell hrisel, tha tak tak siamchhuahna a tlahniam tihna a ni.
Heng dinhmun pahnihah hian harsatna lian ber chu thisen sen hrisel, hnathawk thei zat tlahniam a ni a, chu chu a awmzia a niAnemia a awm thin.
Reblozyl hian thisen sen puitling lo, thang tha lo te chu a puitlin theih nan a pui a ni. Hei hian thisen sen hrisel tak tak a tipung a, hemoglobin level a tisang a, taksain oxygen a phurh theihna a tichak bawk. Chumi avang chuan thisen pek
tam i mamawh lo mai thei .
Mahse hei hi hre reng ang che: Reblozyl hi thisen pekna aiah a ni lo. A mamawhna tihziaawmna tura puitu enkawlna mai a ni.
Engtin nge he damdawi hi pek a nih?
Reblozyl hi in lama ei theih pill a ni lo.
Kar 3 danah shot a ni . He shot hi i doctor office, clinic emaw hospital-a doctor emaw nurse emaw trained-in a pe thin a ni.
- Vaccine pekna hmun: He vaccine hi a tlangpuiin kut, kekawr, emaw pum vun hnuaiah, kekawr hnuai lamah pek thin a ni.
- A hun taka vaccine lak: Doctor-in a pek ni vek a vaccine lak tura kal a pawimawh hle. Ni i tlai chuan doctor ko nghal la, a tuk lo thleng turah thurawn dil rawh.
- Symptom diary: Nitin i symptoms (chauhna leh luak chhuak ) te chu notebook-ah emaw, i phone-ah emaw ziak chhuah a tha. Hei hian i doctor hnenah damdawi in a nghawng dan sawifiah a awlsam phah ang.
I damdawi pek tur zat tur chu i taksa rihna leh i taksain damdawi a dawn dan a zirin i doctor-in a ruat ang.
Side effect awm thei te chu engte nge ni? Engtin nge an hmachhawn ang?
Damdawi dang ang bawkin Reblozyl hian side effect engemaw zat a nei thei a ni. Mi zawng zawngin kan hmu vek lo a, mahse fimkhur a pawimawh. A hnuaia table-ah hian side effects awm fo thin thenkhat leh a enkawl dan tur tarlan a ni.
| Side Effect a awm thei | Engtin nge kan enkawl ang |
|---|
| Chauh lutuk, luak chhuak, taksa thunun theih loh | He damdawi hian engtin nge a nghawng tih chiang taka i hriat hma chuan lirthei khalh emaw, machine rit tak tak hman emaw kha pumpelh rawh. |
| Lu na, taksa ruh emaw ruh na emaw | Heng symptoms te tihziaawmna tura pui thei painkillers te hi i doctor hnenah zawt rawh. I symptoms a that loh emaw, a zual emaw chuan doctor hnenah hrilh rawh. |
| Luak chhuak, pum na, luak chhuak (flatulence) . | Chaw lian ei ai chuan chaw te te ei tum zawk ang che. Chhangphut, crackers, leh buhfai ang chi ei tur hmin lo ei rawh. Tui tam tak in thin ang che. Heng symptoms te hi a zual emaw, a tha lo emaw a nih chuan doctor hnenah hrilh rawh. |
| Thisen sang lutuk | Exercise neih a pawimawh a, DASH ang chi ei leh in hrisel tak hman a pawimawh bawk. I thisen sang kha enfiah fo thin ang che. I thisen sang 180/120 mmHg aia sang a nih chuan Emergency Department (ETU) ah kal nghal tur a ni. |
| Thâwk harsa, Allergic reaction | Allergy natna lan chhuah dan (e.g., vun rawng, hrual, hmai hring, thawk hah) te chu doctor zawt hmasa phawt ang che. Heng symptoms te hi i neih chuan doctor ko nghal la, a hnai ber Emergency Department (ETU) ah kal rawh . |
| Taksa chhunga tui awmkhawm (edema) . | I kut, ke, taksaah a hring chhuak tih i hriat chuan doctor hnenah hrilh rawh. A tul anga enkawlna a pe ang. |
Damdawi dangah harsatna a awm thei em?
Awle. Reblozyl ei hian damdawi dang thenkhat i ei chuan harsatna a thlen thei. A bik takin, menopause emaw birth control pill emaw atana hormone replacement therapy i ei a nih chuan thisen zam a awm theihna a sang thei hle.
Chuvangin, i damdawi ei zawng zawng, doctor-in a pek te , over-the-counter damdawi te, vitamin te, traditional medicines te, leh herbal products te pawh hi i doctor hnenah hrilh ngei ang che.
Take-Home Thuchah a ni
- Reblozyl hi damdawi thar tak a ni a, beta-thalassemia leh MDS an tih natna avanga thisen tlakchhamna (anemia) enkawlna atana shot anga pek a ni.
- Hei hian thisen sen puitling lote chu a lo thang lian tha hle a ni.
- He damdawi hian thisen pek fo ngaina a tiziaawm thei a, mahse thisen pek thlakna tur a ni lo.
- He vaccine hi doctor emaw nurse emaw in kar 3 danah a pe thin.
- Side effects, lu na, hahna, leh taksa ruh na te a awm thei. I doctor nen symptom danglam tak tak i neih chuan sawipui rawh.
- Damdawi dang i ei zawng zawng chu i doctor hriattir a pawimawh hle.
Reblozyl, thisen tlakchhamna, Beta-Thalassemia, Myelodysplastic Syndromes, MDS, thisen pek, Luspatercept, hemoglobin
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