Thalassemia chungchanga hriat tur awmte

I chhungkuaa mi emaw, i hriat mi emaw chuan "anemic" an tih i hre ngai em? A chang chuan an chau reng a, an vun chu a sen leh sallow hmel hle. Hei hi thisen tlakchhamna pangngai a ni thei ang em? Ni e, a pangngai lo mai thei, thisen natna rochun thalassemia an tih pawh a ni thei. He hming i hriat hian hlau suh. Hei hi natna hrik kai theih a ni lo. Engkim hi awlsam tak leh chiang takin sawi ila.

Thalassemia hi eng nge ni tak tak ?

A awlsam zawngin sawi ila, thalassemia hi kan nu leh pate hnen atanga kan rochun thisen natna a ni. Hetiang natna vei hian thisen sen hrisel leh protein hemoglobin tih chu a siam chhuah dan pangngai aia tlem a nei a ni.

Ngaihtuah teh, red blood cells hi kan taksa pum puia oxygen phurtu delivery service a ni. Hemoglobin hi box bik ang a ni a, chu oxygen chu a pack a, a phur a ni. Thalassemia veiah chuan heng delivery vehicle (red blood cells) leh oxygen box (hemoglobin) te hi a tam lo emaw, a chhiatna engemaw zat a awm emaw a ni. Chuvangin, taksa peng zawng zawng hian oxygen an dawng tling vek lo. Hei hi anemia kan ti bawk .

Thalassemia hian hming hrang hrang a nei a. Heng hmingte hi i hre tawh mai thei:

• Alpha thalassemia natna a ni
• Beta thalassemia natna a awm
• Cooley-a thisen tlakchhamna (anemia) a nei
• Mediterranean tuipuiah thisen tlakchhamna (anemia) a awm

Engtin nge thalassemia hi a lo awm? Tute nge hlauhawma awm?

Thalassemia hi ei leh in emaw, tui emaw, mi dang atanga kan kai theih natna a ni lo. Nu leh pa atanga fate hnena genes hmanga inthlunzawm vek thil a ni.

Hemoglobin an tih protein siam nan hian thil pawimawh pahnih a awm a. Alpha globin leh beta globin te an ni. Hengte siam dan tur "recipe" hi kan genes ah hian a awm a ni. Heng genes-ah hian tihsual (recipe-a tihsual) a awm chuan taksain a tul angin hemoglobin hrisel a siam thei dawn lo.

• Nu leh pa pakhat chauh atanga gene chhia i rochun chuan: Carrier i ni thei. Hei hian symptom i nei lo emaw, i nei tlem hle emaw a ni thei tihna a ni a, mahse gene chhia chu i fate hnenah i pe thei a ni.
• Nu leh pa pahnih atanga gene chhia i rochun chuan: Thalassemia na lo, na lo, emaw, na tak emaw i vei thei.

Hetiang dinhmun hi Asia ram Sri Lanka, Middle East, Africa, leh Mediterranean ram Greece leh Turkey-a mite zingah hmuh tur a awm tlangpui.

Thalassemia chi hrang hrangte chu engte nge ni?

Thalassemia hi chi hnih ah then a ni a, hei hi hemoglobin formula a eng part nge a chhiat tih a zirin a ni.

Alpha Thalassemia chi hrang hrang

• Carrier status: Gene 1 dik lo nei. Symptoms a awm lo.
• Alpha Thalassemia Minor: Gene 2 tha lo a nei. Symptoms a awm lo emaw, a na lo hle emaw a ni.
• Hemoglobin H Natna: Gene 3 tha lo a nei. A natna lan chhuah dan chu a hniam lam atanga na tak a ni.
• Alpha Thalassemia Major: Gene 4 chhia zawng zawng nei vek. Hei hi dinhmun pawi tak a ni. Naute hi a pum chhungah emaw, a pian hnu rei vak lovah emaw a thi fo thin.

Beta Thalassemia chi hrang hrang

• Beta Thalassemia Minor: Gene 1 dik lo nei. Symptoms nei lo emaw, a na lo hle emaw (carrier state).
• Beta Thalassemia Intermedia: Gene 2 tha lo a nei a. Symptoms a hniam lam (moderate) a awm.
• Beta Thalassemia Major / Cooley’s Anemia: Gene 2 chhia a awm. Hei hi symptoms na tak tak nei condition a ni.

Thalassemia natna lan chhuah dan chu engte nge ni?

Thalassemia i neih chi leh a nasat danah a symptoms a innghat. Mi thenkhat chuan symptom engmah an nei lo mai thei. Nausen chi hrang hrangah chuan naupang kum 2 a tlin hmain symptoms a lang tlangpui.

A pawimawh ber chu heng symptoms te hi mi zawng zawngah a inang vek lo. Thalassemia pakhat emaw a aia tam emaw i neih vang mai maiin i vei tih ngaihtuah suh. Ringhlelna i neih chuan Doctor pan ngei ngei tur a ni.

Hengte hi a lan chhuah dan tlangpui thenkhat chu an ni:

• Chauhna leh hah lutuk
• Thâwk harsa , thawk hah
• Luak chhuak leh chak lohna
• Vun dum emaw, sen emaw
• Zun dum
• Chaw chakna
• Naupangte thanlenna tlahniam leh puitlin hun sawn hlat
• Hmêl pianzia dik lo (a bik takin hmai leh hmui ruh langsar) .
• Abdomen chhuak (liver emaw spleen emaw a lian vang) .
• Lu na fo thin
• Ruh chak lo leh awlsam taka chhe thei

Engtin nge thalassemia i vei tih i hriat theih ang?

A tlangpuiin, symptom i neih loh chuan chhan dang avanga thisen test pangngai tih laiin accident-in a hriat theih a ni. Symptom i neih chuan i doctor chuan a enfiah ang che a, i chhungkaw medical history a zawt ang che.

Chumi hnuah chuan thisen test bik thenkhat tih a tha a, chungte chu:

• Complete Blood Count (CBC): Hei hian thisen chhunga thisen sen leh hemoglobin awm zat a tehna a ni. Hengte hi thalassemia vei zingah a hniam tlangpui.
• Hemoglobin Electrophoresis: Hei hian i thisena hemoglobin chi hrang hrang awm leh engzat nge awm tih chiang takin a hril thei a ni.
• Genetic Testing: He test hian eng thalassemia chi nge i neih tih chiang taka hriat theih nan a pui a ni.

Naupai laia natna hriatchhuah

Nangmah emaw, i kawppui emaw chu thalassemia carrier i nih chuan i naute chu a pian hmain a natna hi i test thei ang.

• Chorionic Villus Sampling (CVS): Naupai atanga kar 11 vel ah nausen atanga sample te tak te lak a ni a, test a ni.
• Amniocentesis: Naupai kar 16 vel ah naute chhehvel amniotic fluid sample lak a ni a, test a ni.

Hetiang dinhmun hi hmuhchhuah a nih chuan hematologist hnenah refer i ni ang.

Thalassemia enkawl dan tur chu engte nge ni?

Enkawlna chu a natna nasat danah a innghat a ni. Thalassemia minor ang chi natna na lo tak nei chuan enkawlna engmah a mamawh lo mai thei a, mahse a nasat chuan dam chhung enkawl a ngai thung.

Enkawl dan tlangpui chu:

1. Thisen pek dan

Thalassemia na tak nei damlote chuan thisen pek an mamawh a, chu chuan thisen sen hrisel leh hemoglobin a pe thei a ni. A tlangpuiin kar 2-4 danah thisen pek an ngai thin . Hei hian hah lova an thil tih pangngai chhunzawm zel turin chakna a pe a ni.

2. Chelation Therapy hmanga enkawlna

Thisen pek fo leh damdawi lam dinhmun avang hian taksaa iron awm zat hi a tul lovah a pung thei a ni. Hei hi Iron Overload'' kan ti a ni.He extra iron hi thinlung leh thin ang chi taksa peng pawimawh tak takah a awm khawm thei a, a tichhia thei bawk.

Chuvang chuan thisen petute chu an taksaa thir tam zawk awm khawm chu paih chhuah nan damdawi bik pek an ni. Hei hi Chelation Therapy an ti a. Heng damdawi te hi pill angin emaw, injection angin emaw ei theih a ni.

3. Enkawlna dang

• Bone Marrow emaw Stem Cell Transplant: Donor hrisel tak hnen atanga bone marrow transplant hian a chang chuan thalassemia hi a tidam vek thei. Mahse, hei hi a hlauhawmna leh a inmil tur donor hmuh a harsat avangin tih a ni fo lo.
• Surgery: Damlo thenkhat chuan an spleen a lian a, chu chu surgery hmanga lakchhuah (splenectomy) a ngai a ni.
• Damdawi: Damdawi Luspatercept (Reblozyl) leh Hydroxyurea te hi thisen zam (red blood cells) siam chhuahna atan leh natna lan chhuah dan control nan hman a ni.
• Supplements: I doctor chuan folic acid ang chi vitamin a rawn rawt thei a, hei hian thisen zam (red blood cells) a siam thei a ni. Amaherawhchu, damdawi lam thurawn tel lo chuan iron supplement hi eng vang pawhin ei loh tur a ni.

Thalassemia natna vei hian engtin nge hrisel taka kan nun theih ang?

Thalassemia vei tan chuan nun hrisel leh hlim taka a awm theih nan heng thilte hi enkawl hi a pawimawh hle.

• I doctor thupek zawm rawh: I doctor enkawl dan tur chu a tih ang chiah, a hun takah zawm la, clinic-ah pawh kal ngei ngei tur a ni.
• Ei leh in hrisel: Ei leh in inthlau tak, thei leh thlai tam tak ei thin ang che. Iron tamna ei tur (sa, sangha, legumes) leh iron tamna ei tur tihtlem a ngai em tih doctor zawt rawh.
• Vaccine la rawh: I doctor-in a rawt vaccine zawng zawng, a bik takin flu shot ang chi te chu la vek rawh, a chhan chu natna kai theihna a sang zawk thei a ni.
• Insawizawi:I taksa nena inmil exercise light tak nei rawh. Chumi chungchang chu i doctor nen sawiho rawh.
• Faina: Mi damlote lakah inthiarfihlim rawh. Kut sil fo thin ang che.
• Meizial leh zu in loh tur: Hengte hi i thinlung leh ruh tan a tha lo.
• Rilru hriselna: Natna khirh tak nena nun hi rilru hahna a ni thei. I rilru hah emaw, lungngaihna emaw i neih chuan, chhûngte, ṭhiante, a nih loh leh rilru lam hrisêlna lama thurâwn petu hnênah sawiho rawh .