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SIADH hi eng nge ni tak tak?
A awlsam zawngin sawi ila, SIADH hi i taksain hormone Antidiuretic Hormone (ADH) a siam tam lutuk, a nih loh leh a dik lo taka a siam chhuah theihna a ni. He ADH hormone hi Vasopressin an ti bawk. He ADH hormone hi kan thluaka hypothalamus ah siam a ni. Chumi hnuah chuan posterior pituitary gland -ah dahin, a tul hunah taksaah a chhuak leh thin. Tunah chuan he ADH hormone hian kan taksaah eng thil pawimawh nge a puih tih hi han en ila:- Kan thisena tui leh sodium ( chi ) awm zat inthlauhna vawng reng.
- Thisen sang control nan a pui thin .
- Kidney hnathawh thatna tur a pui thin.
SIADH hian tute nge a nghawng tam ber?
Dik tak chuan tu pawhin SIADH an nei thei. Mahse, kum upat deuh deuh hian he natna hi a vei theihna a sang chho zel a ni. A tlangpuiin, he SIADH an tih hi a tam ber chu:- Damdawi in-a zai atanga dam lehte zingah hian operation hnua tui pek te, damdawi thenkhat, leh taksain natna leh lungkhamna a dawn dan avang te hian a thleng thei a ni.
- Lung cancer vei zingah, a bik takin Small Cell Lung Cancer ( SCLC )'' tih chi khat nei zingah.
Hetiang dinhmun hi engtiang chiahin nge SIADH tia koh a nih?
SIADH hi a awm fo thin. A hmaa kan sawi tawh Hyponatremia (thisenah sodium tlem) hi damdawi ina awm damlote zingah Electrolyte imbalance hmuh tam ber a ni. SIADH hi Hyponatremia thlentu ber a ni.
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Check Availability →Engtin nge SIADH hian hyponatremia a thlen?
I tuihal hle tih han ngaihtuah teh. I taksa hian eng nge a tih? Taksa chu hormone ADH chhuah tir turin signal a pe a ni. Tichuan, kal (kidney) hian zun atanga tui chhuak chu a ti tlem a, chu tui chu taksa chuan a vawng reng a ni. Tui i in hian i tuihalna a reh chuan taksain ADH a chhuah tawh lo va, kal (kidney) chuan zunah tui a chhuah leh tan a, a pangngaiin a chhuak leh ta a ni. Hei hi thil kalphung pangngai a ni. Amaherawhchu SIADH vei tam takah chuan tui in hnuah pawh hormone ADH tihchhuah hi a tlahniam tha tawk lo. Chuvangin an zun chu a concentrate hle (tui tlem leh bawlhhlawh tam tihna a ni). Hei hian taksaah tui a khawlkhawm thin. He tui hi a lo awm khawm chuan thisena sodium ang chi thilte chu a diluted ta a ni. Chu chu thisenah sodium level a tlahniam a, chu chu Hyponatremia an ti a ni. SIADH thenkhatah chuan taksain tui a tam lutuk chuan kal (kidney) te chu zun atanga chi (sodium) tam lutuk chhuah tir turin signal a awm thin. Hei hi hyponatremia thlentu dang a ni bawk.SIADH natna lan chhuah dante chu engte nge ni?
SIADH i neih chuan i zun chu a concentrate hle. Chumi awmzia chu bawlhhlawh a tam lutuk a, tui a tlem lutuk tihna a ni. I taksain a tlangpuiin zun hmanga tui a paih chhuah loh avangin i thisena tui awm zat chu a pung zel a ni. Hei hian i thisenah sodium ang chi thil a ti dilute a ni.Thisena sodium level hniam (hyponatremia) hi SIADH natna lan chhuah chhan ber a ni.A tam zawkah chuan sodium level hniam deuh pawhin symptom lian tham a thlen lo. Mahse, sodium level a hniam lutuk emaw, a hniam lutuk emaw a nih chuan heng ang symptoms hi a awm thei a ni:
- Muscle twitching emaw chak lohna emaw. I ke chu a hrual mai mai ang maia i hriat kha han mitthla teh.
- Nausea leh luak chhuak .
- Lu na .
- Balance lama harsatna, a chang chuan tlu thei.
- Rilru lama inthlak danglamna, ngaihtuahna seng harsa, hriatrengna hloh, leh/ emaw nungchang mak tak tak te.
- A nasat chuan seizure emaw coma emaw a awm thei.
SIADH awm chhante chu engte nge ni?
A tam zawkah chuan SIADH hi damdawi lam thil dang vang a ni. Hereditary SIADH (chu chu thlah kal zelah a kal zel tihna) hi a tlem hle.Kidney-a Vasopressin 2 (V2) receptor-a gene mutation vang a ni. SIADH lo awm chhan fotu dinhmun leh chhan thenkhat chu hetiang hi a ni:- Cancer chi thenkhat: Tumor thenkhat chuan anmahni ADH hormone an siam chhuak thei. Hei hian taksaah ADH tam lutuk a thlen thei a, SIADH a thlen thei a ni. Small cell lung cancer (SCLC) hi cancer chi hrang hrang zingah hetianga ADH siam chhuaktu tam ber a ni. Tin, cancer te, lung pawn lama lo awm small cell carcinoma te, lu leh kawng cancer te, olfactory neuroblastomas te pawh hian SIADH a thlen thei bawk.
- Central Nervous System (CNS) lama harsatna: Kan central nervous system hi thluak leh ruhro atanga siam a ni. He system-a thil dik lo eng pawh, stroke, thluaka thisen chhuah, natna kai, hliam, emaw, a tlem berah chuan rilru lam natna (psychosis) te hi SIADH a thlen thei a ni.
- Damdawi thenkhat: Damdawi thenkhat hian hormone ADH release emaw activity emaw a tipung thei. Chuvangin SIADH a lo thleng thei a ni. Entîr nân, epilepsy damdawi ṭhenkhat, lungngaihna damdawi, cancer damdawi, leh lung natna, zunthlum, leh thisen sang damdawi ṭhenkhat.
- Anesthesia hnuaia surgery: SIADH hi surgery nen a inzawm thei. Hei hi taksain rilru leh taksa lama harsatna a tawh vang pawh a ni thei.
- Lung natna: Lung natna, a bik takin pneumonia (virus, bacteria, tuberculosis avanga lo awm) hian SIADH a thlen thei. Zirchiangtute chuan hetiang thil hi a thlen chhan an la hre chiang lo.
- Hormone tlakchhamna: Hypopituitarism (underactive pituitary gland) leh Hypothyroidism (underactive thyroid gland) an tih hian SIADH a thlen thei a ni.
Engtin nge SIADH hi hmuhchhuah a nih?
Hyponatremia (thisenah sodium tlem) symptom i neih chuan i doctor chuan taksa enfiahna kimchang a ti ang. I fluid status pawh an check bawk ang. Hei hi diagnosis dik tak siam nan a pawimawh hle. I dehydrated, overhydrated, a dik chiah em tih an enfiah ang. SIADH hriat theihna tur test tha ber pakhat mah a awm lo. I thisena ADH level enfiah thei test awm mahse, result a lo chhuah leh theih nan kar hnih vel a ngai thei. Chuvangin, i doctor chuan hyponatremia enfiah nan test dang a ti mai thei a, chu chu:- Metabolic Panel (CMP) hmanga siam a ni.
- Thisen osmolality test a ni.
- Zun Osmolality Test a ni.
- Zun sodium leh potassium test.
- Damdawi thenkhat tan Toxicology Screens a awm.
SIADH hi engtin nge enkawl a nih?
SIADH enkawl dan chu a chhanah a innghat. Entirnan, ADH siamtu tumor i neih chuan i doctor chuan operation tihchhuah a rawt thei ang. He natna hi damdawi avanga lo awm a nih chuan i doctor chuan damdawi dose a thlak thei a, damdawi dang a pe thei bawk. SIADH vei zawng zawngah hian a hmasa ber chu tui i in zat tihtlem hi a ni. Hei hian i taksain tui a vawn tam lutuk loh nan a pui a ni. I doctor chuan nitin tui i in tur zat (tui, coffee, tea leh sugary drinks te pawh tel) a hrilh ang che. Hyponatremia symptom na tak tak (confusion, seizures ang chi) i neih chuan medical emergency a ni. Hei hi damdawi inah saline (IV hmanga pek chhuah chi solution) vein-a pek hmanga enkawl a ni tlangpui. I kal (kidney)-a ADH hormone-in nghawng a neih loh nan damdawi i mamawh thei bawk. Tichuan kidney te hian signal an dawng a, taksaa tui tam lutuk chu zun hmangin an paih chhuak tan ta a ni.SIADH hi ven theih a ni em?
SIADH awm chhan tam tak a awm avangin ven a harsa tlangpui. SIADH emaw hyponatremia emaw i vei thei tih i ngaihtuah chuan doctor nen inbia ang che.SIADH hi eng prognosis nge ni?
SIADH hmalam hun chu a chhan bulpuiah a innghat a ni. Thu lawmawm tak chu SIADH thlentu tam tak hi tihdanglam theih leh/ emaw enkawl theih a ni. Acute hyponatremia, darkar 48 aia rei lova lo awm hi a hlauhawm zawk a, hun kal zelah zawi zawia lo awm thin hyponatremia aiin a hlauhawm zawk. Chronic hyponatremia hi thluak lam harsatna (e.g., balance hloh, hriatrengna hloh) nen a inzawm a ni. SIADH a nasat a, thisena sodium level a tlahniam lutuk chuan a hnuaia mi hi a thleng thei a ni:- Thil hriatna hloh, hallucinations, emaw coma emaw.
- Thluak Herniation a awm.
- Thihna.
SIADH chungchangah engtikah nge doctor i hmuh ang?
Hyponatremia symptoms, muscle cramps leh balance problems te i neih chuan doctor nen inbia ang che. Heng symptoms te hi chhan hrang hrang a awm theih avangin i doctor hian test hrang hrang a nei ngei ang.Hyponatremia na tak symptoms, confusion, delirium, seizures i neih chuan a rang thei ang bera damdawi in hnai ber pan rawh.SIADH hi natna tlanglawn tak a ni a, a chhan hrang hrang a nei thei bawk. Damdawi ina awm tawhte a nghawng fo thin. Amaherawhchu, SIADH natna lanchhuahna, rilru hahna emaw, rilru lam inthlak danglamna emaw i neih chuan doctor nena inbiakna neih a pawimawh.
Thil pawimawh tak tak hriat reng tur (Take-Home Message) .
Okay, chuvangin tunah chuan vawiin a kan sawi SIADH hi in hriatthiam ka beisei.- SIADH hi taksain tui a vawng reng a, hormone ADH a siam chhuah tam lutuk avangin thisenah sodium a tihtlem phah a ni.
- Hei hi chhan tam tak a awm thei a; thil cancer, damdawi thenkhat, surgery, lung natna, etc. ang chi te.
- A lan chhuah dan chu rilru hahna, luak chhuak, luak chhuak, leh rilru lam inthlak danglamna te a ni thei . A nasat chuan seizure leh hriatna hloh a awm thei.
- Enkawlnaah chuan tui control te, a chhan enkawl te, leh a tul chuan saline emaw damdawi emaw pek te pawh a tel thei .
- A pawimawh ber chu, heng symptoms te hi i neih chuan hlauthawng suh la, doctor thurawn la nghal rawh. Chutiang chuan thil dik lo dik tak chu i hre thei ang a, a tul anga enkawlna chu i tan thei ang.
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