Nangmah emaw, i hriatte emaw pawhin ‘Siltuximab’ (brand name: Sylvant) tih damdawi an lo pe tawh a ni mai thei. He hming hriat hi thil mak deuhin a ri mai thei, a chhan chu hei hi nitin kan hriat leh damdawi dawr atanga kan lei damdawi a ni lo. Chuvangin, hlau suh. Vawiin hian he damdawi bik Siltuximab tih hi kan sawi dawn a, a enkawl dan te, he damdawi ei huna fimkhur tur thilte kan sawi dawn a ni.
A awlsam zawngin Siltuximab hi eng nge ni?
Kan taksa hian immune system a nei niin han ngaihtuah teh. Hei hi natna thlentu hrik leh virus dotu a ni. He system hian sipai ang chi bik a nei a, chu chu ' antibodies ' kan ti a ni. Siltuximab hi chutiang chu a ni a, mahse laboratory-a siam artificial antibody chi khat bik tak a ni. A dik zawka sawi chuan ‘monoclonal antibody ’ a ni. A hna chu taksaa natna thenkhat thlen theitu protein bik zawng chhuakin, a target a, hnathawh lohna tur a titawp a ni.
He damdawi hi natna hlauhawm tak , multicentric Castleman disease (MCD) tih enkawlna atan hman a ni ber. Hei hi kan lymph node-a cell te chu thunun theih loha an lo thang lian thinna dinhmun a ni. Siltuximab hian he cell duh loh zawng tipungtu protein pakhat control-in hna a thawk a, chu chuan natna chu a control thei a ni.
Enkawlna i tan hmaa i doctor hnena i hrilh tur thilte
He enkawlna hi i tan a tha em tih hriat nan i medical team te hian i hriselna dinhmun an hriat chian a pawimawh hle. Chuvangin, a hnuaia tarlan te hi i neih chuan thup lovin i doctor hnenah hrilh ngei ang che .
| Situation i report tur a ni | Hrilhfiahna |
|---|---|
| Tuna hri kai mek te | HIV emaw AIDS emaw i vei a nih chuan, emaw, tunah hian natna chi dang (khawsik, khuh, khawsik) i neih chuan, virus infection chickenpox emaw herpes emaw te pawh a tel. |
| Vaccine pek dan tur | Tun hnaia vaccine i dawng tawh emaw, dawng thuai tura ruahman i nih chuan. |
| Pum emaw, intestinal emaw lama harsatna nei | Pum natna, gastritis emaw a kaihhnawih harsatna dang i neih chuan. |
| Allergy nei te pawh a awm | Siltuximab emaw damdawi dang emaw, ei tur emaw, dye dang emaw allergy i neih chuan. |
| Naupai leh nau hnute pek | Naupai i nih chuan, nau pai tum i nih chuan, nau hnute i pe a nih chuan. |
Engtin nge he damdawi hi i hmuh theih?
Hei hi in lama i hruai theih tur pill emaw syrup emaw a ni lo. Siltuximab hi infusion a ni a, taksaah thisen kaltlangin pek a ni. A awlsam zawngin sawi ila, saline ang mai a ni. Hospital emaw clinic emaw-ah chauh pek a ni a, trained medical professional enkawlna hnuaiah pek a ni .
Pawimawh: He damdawi hi doctor-in a pek aia tam i ei tawh nia i hriat chuan damdawi in hnathawkte hnenah hriattir nghal rawh. Emergency a awm chuan Emergency Treatment Unit (ETU) ah direct in kal rawh. Colombo National Hospital-a National Poisons Information Center-ah pawh zawhfiah theih a ni bawk.
Enkawlna a awm loh chuan engtin nge ni ang?
I dose ruahman i pelh chuan i doctor ko nghal rawh . I dose leh tur chu engtikah nge i lak tur tih a rel ang. I dose a hun taka lak hi i enkawlna hlawhtlinna atan a pawimawh hle.
Damdawi dang siltuximab nena inzawm thei
Siltuximab hian damdawi dang i ei lai nen a inzawm thei a ni. Hei hi ‘drug interaction’ an ti a. Chuvangin, i damdawi ei zawng zawng (doctor dangin an pek te, over-the-counter damdawi, vitamin, hnam damdawi, leh Ayurvedic damdawi thlengin) i doctor hnenah i hrilh vek tur a ni.
Damdawi chi hrang hrang harsatna thlen thei ber thenkhat chu:
- `atorvastatin`, `lovastatin` (cholesterol tihhniamna damdawi) te hi a ni.
- Naupai venna damdawi
- `cyclosporine` (i taksa hriselna tichhe thei damdawi) .
- Virus nung vaccine pek a ni
- `theophylline` ( thluak lam natna, asthma ang chi damdawi hman thin ) .
- `warfarin` (thisen zawrh tur venna damdawi ) .
He list hi a kim lo tih hre reng ang che. A him ber chu i ei zawng zawng doctor hnenah hrilh vek hi a ni.
Enkawl laia i hriat tur thilte
Infection lakah inveng rawh
He damdawi hian i taksain natna a do theihna (immunity) chu tlem a ti tlem a ni. Hei hian natna hrik i kai theihna a tipung zawk a ni .
- Khawsik, khawsik, rilru na, khuh ang chi symptoms i neih chuan mahni invenna nei suh la, i doctor hnenah hrilh nghal rawh .
- Mipui tamna hmuna kal leh damlo hnaih hi a theih ang anga tih tlem.
Naupai leh nau neih dan tur
Hei hi thil pawimawh tak a ni.
- Siltuximab ei lai hian naupai venna pills hi a hlawk lo zawk thei . Chuvangin, naupai venna hmanraw dang, condom ang chi hman chungchang hi i doctor nen sawiho rawh.
- He damdawi i ei lai hian naupai hi i pumpelh vek tur a ni a, a hnuhnung ber i ei hnu thla 3 chhung chu , nausen piang lai tan harsatna nasa tak a thlen theih avangin.
- Naupai i beisei emaw, naupai tih rinhlelhna tlemte pawh i neih chuan doctor hnenah hrilh nghal rawh.
Nau hnute pek
He damdawi hi i ei lai leh a ei hnuhnung ber atanga thla 3 chhung chu naute hnute pe suh .
Damdawi lam test neih a ni
Enkawl lai hian i doctor chuan i dinhmun enfiah turin thisen test turin a ti fo ang. I enkawlna hlawhtlinna tur chuan heng test te hi a hun taka tih leh skip lovin tih a pawimawh hle.
Damdawi hmansualna (side effects) te
Damdawi dang ang bawkin Siltuximab hian mi thenkhatah side effect a nei thei a ni. Heng zinga a tam zawk hi chu thil pawi tak a ni lo, mahse a bik taka fimkhur tur thil engemaw zat a awm.
| Side effect a awm thei | Hrilhfiahna |
|---|---|
| I doctor emaw damdawi ina thawktute hnena hriattir nghal tur symptoms | |
| Allergic Reaction awm thei te | Skin rash, itching, hmai, hmui, lei hring. |
| Thâwk harsa | Thâwk hah, rilru hah lutuk tih hriat. |
| Heart rate a inthlak danglam thin | I thinlung chu a na rang emaw, a thawk mumal lo emaw ang maia inhriatna, muhil. |
| Hri kai theihna chhinchhiahna | Khawsik, khawsik, ril na, zun laiin na. |
| Symptom na tak dang a awm bawk | Lu na na tak, pum na, hnungzang na, luak chhuak, luak chhuak. |
| Symptoms a awm reng emaw, a buaithlak emaw a nih chuan doctor hnenah report tur | |
| A taksa rihna a tipung | Rihna a sang chho zel. |
| Ke a hring chhuak | Ke emaw ke ruh emaw a hring (swelling) a awm. |
| Chaw ei leh in lama inthlak danglamna | Constipation emaw riltam emaw. |
Take-Home Thuchah a ni
- Siltuximab hi natna hlauhawm tak, multicentric Castleman disease (MCD) an tih enkawlna bik a ni a, damdawi inah vein hmanga pek thin a ni.
- I natna dang leh damdawi i ei zawng zawngte chu enkawl tan hmain doctor hnenah hrilh hmasa phawt ang che.
- He damdawi hian taksa invenna a ti tlem thei a ni. Chuvangin, natna hrik kai lanchhuahna, khawsik leh khuh ang chi i neih chuan doctor hnenah hrilh nghal rawh.
- Enkawl lai leh chawlhsan hnu thla 3 chhung chu naupai loh tur a ni. Naupai tihtlem dan dang hmang bawk ang che.
- Side effect na tak tak, allergy emaw thawk harsa emaw i neih chuan doctor lam pan nghal rawh.
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