I pum natna pawh tihdam theih loh i nei em? VIPoma (Vasoactive Intestinal Peptide Secreting) tumor chungchang hi i zir dawn teh ang!

A châng chuan ni tam tak chhûnga rilṭâm na tak, pum na leh rilṭâmna i nei ṭhin em? Engmah i ei lo emaw, i in lo emaw pawh a ni thei, mahse hetiang hian i la inhria. Hetiang symptoms i neih chuan a chhan hi a tlem hle mai thei a, mahse kan sawi tur tak tak condition a ni thei. Vawiin hian chutiang dinhmun pakhat VIPoma , emaw `Vasoactive Intestinal Peptide Secreting` tumor tih kan sawi dawn a ni. A hming hi a buaithlak deuhin a lang thei a, mahse a awlsam zawngin i dah ang u.

VIPoma tumor tih hi eng nge ni?

A awlsam zawngin VIPoma hi tumor chi khat, pancreas-a lo awm hi a awm lo hle a ni . A bik takin, hengte hi pancreas-a hormone siamtu cell-a lo awm, endocrine cells -a lo awm tumor an ni. Doctor-te chuan he natna hi `Verner-Morrison syndrome` an ti \hin.

VIPoma tumor hi a tlem hle . America ang ramah pawh he natna hi mi maktaduai sawm zinga pakhat velah a awm niin an sawi. Chuvangin a tlem zia chu i ngaihtuah thei ang. Chutiang natna hlauhawm tak nena nun chu harsatna tak tak a ni thei a, a chhan chu i nitin nunah nghawng lian tak a nei a ni. Mahse, lungngai suh . Tunah chuan he VIPoma natna hi a chang chuan a tidam vek thei a, a tlem berah chuan a natna lan chhuah dan pawh control thei tur enkawlna a awm ta.

VIPoma tumor hian eng symptoms nge a neih?

Hetiang dinhmunah hian a lan chhuahna ber leh pawimawh ber chu ril\am na tak, tui ang chi hi a ni . Hei hi a nasat em avangin chaw ei loh (chaw nghei) pawhin he riltam hi i nei thei a ni. Ni rei lo te chhungin a reh lo. Hei hi he natna chhinchhiahna langsar ber a ni.

Chu bakah chuan symptom dang engemaw zat a awm thei bawk:

• Pum natna emaw, na emaw: I pum chu a inher ang maiin a lang thei a, khawih pawhin a na thei bawk.
• Chauhna: Chau leh nunna nei lo anga inhriatna.
• Flushing: Hmai leh rilru a sen nghal zung zung. Hei hi chhan hriat lohvin a thleng thei a ni.
• Muscle chak lohna: I ke ruhte chu a hring vek ang maiin i inhria thei a, rit phurh pawh a harsa thei bawk.

Ni khatah tui bottle hnih emaw, pathum emaw chu bawlhhlawh atan i sem chhuak a nih chuan engtin nge i awm ang tih han ngaihtuah teh. Hei hi a nasat em avangin nitin hna pawh i thawk thei lo.

Eng thilin nge VIPoma a lo awm chhan?

Mithiamte chuan VIPoma tumor hi eng nge a thlen tih chiang takin an la hre lo a , mahse heng symptoms te hi engtin nge a awm tih erawh chiang takin an hre chiang hle.

Kan taksa hian hormone `Vasoactive Intestinal Peptide` (VIP) tih a nei a. He VIP hormone hian kan chaw ei leh in (digestive system) a tidanglam thin a ni.A pui nasa hle. Chu chu, he hormone hian chaw ei kawng a tui, chi, enzyme leh stomach acid te chhuah dan a control tihna a ni. Tin, chaw ei kawng (digestive tract) chhunga taksa ruh thenkhatte chu a ti hahdam thei bawk.

VIPoma tumor a lo awm chuan taksaah VIP hormone tam tak, a pangngai lo takin a chhuah tir thin. He VIP hormone tam lutuk hi taksaah a luh chuan a hmaa kan sawi tawh ang khan natna lan chhuahna, riltam na tak leh pum na tak te hi a lo lang thin. A awlsam zawngin sawi ila, he tumor hian VIP hormone chu a thawk nasa lutuk a ni.

VIPoma avanga harsatna awm thei te chu engte nge ni?

VIPoma chungchanga harsatna lian ber chu riltam lutuk hi a ni. Mi thenkhat chuan ni khatah tui bawlhhlawh litre khat atanga litre thum (1-3 quarts) vel an pass thei. Hetiang ril\am hi a la awm zel chuan taksain tui leh mineral pawimawh tak tak, a bik takin potassium a hloh nasa hle.

Hei hian hun kal zelah dehydration leh hypokalemia a thlen thei a ni. Heng dinhmun pahnihte hi hriselna lama harsatna lian zawk a thlen theih avangin a hlauhawm hle. Entir nan:

• Heartbeat irregularities (`Arrhythmia`): Thinlung thawk mumal lo.
• Hypovolemic shock: Taksa chhunga tui awm zat tlem avanga lo awm thin.
• Muscle chak lohna (`Myopathy`): Muscle hnathawh that lohna.
• Tetany: Taksa ruh (muscles) a natna (contractions) a awm.

Heng harsatna te avang hian VIPoma natna lanchhuahna i neih chuan doctor lam pan vat a pawimawh hle.

Doctor-te hian engtin nge VIPoma hi an hriat theih?

Ni eng emaw zat atanga lo awm tawh, luak chhuak nasa emaw, pum na emaw ang chi symptom i neih chuan doctor chuan taksa enfiahin i symptoms te a zawt ang .

Stool test pawh tih theih a ni a, chu chuan diarrhea thlentu thil dang (e.g., infection) a awm lo. Tin, a hnuaia test te hi tih theih a ni bawk:

• Thisen test: Hengte hian thisen a VIP hormone level an enfiah ber. VIPoma-ah chuan he level hi a sang hle. Tin, tui tlakchhamna leh potassium tlakchhamna te pawh an enfiah thei bawk.
• Imaging test: Hengte hian taksa chhungril lam thlalak an la a, tumor a awm leh awm loh, a awm leh awm loh, khawiah nge a awm tih leh engtiang chiahin nge a lian tih te an en thin. Hei hian `Computed Tomography (CT) scan` emaw `Magnetic Resonance Imaging (MRI)` test emaw a huam thei a ni.

Doctor-te chuan heng test zawng zawng an neih hnuah VIPoma status hi an nemnghet a ni.

VIPoma hi engtin nge enkawl a nih?

VIPoma enkawlnaah hian damdawi leh operation inkawp a ngai tlangpui. I doctor chuan a hnuaia mi hi a rawn rawt thei ang:

• Thisen chhunga tui (`IV fluids`): .Hengte hi taksa atanga tui leh mineral hloh, riltam chhunzawm zel avanga hloh thlak nan pek thin a ni. Hei hian dehydration control nan a pui thei a ni.
• Damdawi: 1.1.
• Diarrhea hi damdawi ``Octreotide (Sandostatin LAR®)`` hmanga control theih a ni. Heng damdawi te hian hormone VIP tihchhuah a ti tlem a ni.

Hetianga i natna lan chhuah dan a enkawl hmasak hnuah, i doctor chuan tumor tihbo emaw, control emaw dan tur dang a rawn rawt thei ang:

• Surgery: Tumor hi taksa hmun dangah a darh lo (metastasized) , surgery hmangin tumor hi lakchhuah theih a ni. Chumi atan chuan distal pancreatectomy an tih surgery, pancreas tail leh body lakchhuahna chu hman theih a ni. Tumor hi paih vek a nih chuan natna chu a dam thei a ni.
• Chemotherapy: Tumor a darh tawh emaw, surgery hmanga lak chhuah kim theih loh emaw a nih chuan cancer cell tihchhiat nan chemotherapy pek thin a ni.
• Targeted therapy: Heng damdawi te hi cancer cell hmun bik target tu damdawi te an ni.

I medical team chuan i dinhmun uluk taka an enfiah hnuah i tana enkawlna tha ber tur an rel ang.

VIPoma vei chuan eng nge a beisei theih ang?

Hei hi mi hrang hrangah a inang lo tak zet a ni. Surgery hian VIPoma hi a tidam vek thei. Damdawi hian natna lan chhuahna chu nasa takin a thunun thei a ni.

Mahse, mi zawng zawng dinhmun hi a inang vek lo . I thil tawn hi midang VIPoma vei tawh dan nen a danglam hle mai thei. I surgeon leh medical team te hian information tha ber ber leh kaihhruaina tha ber ber pe thei che an ni. Nang leh i dinhmun hi an hre chiang ber a, chuvangin i hriat tur eng pawh zawt rawh.

Engtikah nge Doctor ka hmuh ang?

VIPoma enkawlna i dawng tawh a nih chuan i natna lan chhuah dan a ṭhat loh emaw, a zual emaw chuan doctor ko nghal rawh .

Tin, heng symptoms te hi i neih chuan emergency room-ah kal bawk ang che :

• Pum natna nasa tak i neih chuan .
• Ni engemaw zat chhung chu watery diarrhea i neih tawh chuan .
• If you are showing signs of dehydration , chu chu lu hlim, lu hah, emaw, zun dum emaw, dum emaw i neih te hi a ni.

VIPoma vanga chronic diarrhea hian nitin hnathawh a tibuai thei a, zan mut pawh a tibuai thei bawk. Heng symptoms awm chhan hriat hian hahdamna a thlen thei a ni. Mahse, VIPoma hi natna hmuh tur awm lo tak a nih avangin mi tlemte chauhin an hre chiang hle. Hei hian mahni chauha awm leh lungngaihna a thlen thei che a ni. VIPoma symptoms te pawh i zak mai thei.

I medical team hian heng rilru put hmang hi an hrethiam hle a, chuvangin i mamawh tanpuina dil hreh suh, i natna lan chhuah dan enkawl emaw, chutiang natna hmuh tur awm lo tak nena nun emaw pawh nise.

Kan hriat reng tur pawimawh ber berte (Take-Home Message) .

VIPoma hi tumor rare tak a ni a, pancreas-ah a lo awm thin. VIP an tih hormone a tichhuak nasa lutuk a, chu chuan riltam na tak leh pum na tak ang chi symptoms a thlen thin. Heng symptoms te hi a la awm reng a nih chuan doctor thurawn lak a pawimawh hle. Dehydration leh potassium tlakchhamna ang chi harsatna a awm theih avangin enkawl vat a pawimawh. Enkawlna hrang hrang, zai, damdawi, leh chemotherapy te pawh a awm. Hei hi natna hmuh tur awm lo mah se, nangmah chauh i ni lo. I medical team hnen atangin tanpuina dawng rawh.

` VIPoma, Vasoactive Intestinal Peptide, Pancreatic Cancer, Luak chhuak, Verner-Morrison syndrome, Hormone Imbalances, Natna Rare te