He aha te POEMS Syndrome? Kei te hiahia koe ki te mōhio mō tēnei anō hoki?

Kua rongo kē koe i te mate POEMS? He mate onge tēnei, kāore e tino rangona. Heoi, he mea nui kia mōhio koe ki tēnei mate nā te mea ka pā ki ngā pūnaha maha o roto i tō tātou tinana i te wā kotahi. He māmā noa iho, he mate uaua tēnei e pā ana ki ō tātou toto. I tēnei rā, ka kōrero tātou mō te mate POEMS, he aha ōna tohu, me pēhea te tautuhi i tōna mate, me te mea he rongoā kei reira.

He aha rawa te mate POEMS?

Āe, me titiro tātou he aha te mate POEMS. He mate toto tino onge tēnei. Kei roto i te tinana tētahi momo toto e kiia nei ko ngā pūtau plasma. Ina puta te mate POEMS, ka wehea, ka whakanuia hoki ēnei pūtau plasma, he mea rerekē, kāore e taea te whakahaere. Ka tukuna e ēnei pūtau plasma rerekē tētahi pūmua motuhake ki roto i ō tātou toto. Ka kiia ko te pūmua monoclonal, ko te pūmua-M rānei. Ka taea e koe te whakaaro, tika? Ina nui rawa te pikinga o ēnei pūtau plasma rerekē, arā, te pūmua-M, i roto i te toto, ka kino pea ō tātou io me ngā whekau o roto.

I ahu mai te ingoa POEMS i ngā reta tuatahi o ngā tohu matua e rima o tēnei mate:

• P - Polyneuropathy: E pā ana tēnei ki te kino o ngā io puta noa i te tinana. I roto i ngā POEMS, ka taea e tēnei kino te whakararu i te mamae, i ētahi atu kare ā-roto rānei (pēnei i te ngau, te wera, me ētahi atu) i roto i ō waewae, ringa, kapu waewae, me ō ringaringa.
• O - Organomegaly: Ko te tikanga tēnei ka nui rawa ngā whekau o roto. Tērā pea ka nui haere ngā whekau o te tangata whai POEMS pērā i te ate, te whēkau, me ngā kōpū lymph.
• E - Endocrinopathy: Ki te kī māmā noa, he raruraru homoni tēnei. I roto i te POEMS, he rerekē te nui o ngā homoni e tukuna ana e ō tātou repe endocrine. Tērā pea ka nui rawa, ka iti rānei te nui o ētahi homoni e tukuna ana.
• M - Pūmua Monoclonal (M-protein): Koinei te pūmua motuhake e kohia ana i roto i te toto i roto i ngā POEMS. Ina hanga e te pūtau plasma kotahi he maha ngā tārua (tārua) o ia anō, ka tāpirihia e ia pūtau tēnei pūmua-M ki te toto. Ā tōna wā, ka tino piki ake te nui o te pūmua-M i roto i te toto.
• S - Ngā panonitanga kiri: Tērā pea ka pāngia te hunga whai POEMS e ngā panonitanga kiri maha, pērā i te pōuriuri o te kiri me te matotoru o te kiri.

E mōhiotia ana hoki te mate POEMS ko te osteosclerotic myeloma , te mate Crow-Fukase , te mate PEP , me te mate Takatsuki .

Ko wai te mea tino tūpono ka pāngia e te mate POEMS?

He tino onge te mate POEMS. He tokoiti noa iho ngā tāngata e pāngia ana puta noa i te ao. Ko te nuinga o te wā ka kitea i waenga i te 50 me te 60 tau te pakeke. Ka pāngia pea ngā ira e rua, engari he nui ake te kitea i roto i ngā tāne.

He aha ngā tohu o te mate POEMS?

E ai ki tā mātou i kōrero ai i mua ake nei, ko ngā reta i roto i te ingoa POEMS e tohu ana i ētahi o ngā tohu matua. Arā, ko te Polyneuropathy, te Organomegaly, te Endocrinopathy, te M-protein elevasion, me ngā huringa kiri ngā tohu matua. Tata ki te katoa e pāngia ana e te POEMS he polyneuropathy me te M-protein elevation. Tērā pea ka rerekē ētahi atu tohu i ia tangata, i ia tangata.

Ngā tohu i puta mai i te polyneuropathy

Ko ngā tohu i puta mai i tēnei kino o te io te mea tino kitea i roto i ngā POEMS. I te nuinga o te wā, ka tino pāngia ngā waewae me ngā waewae e te mamae. Engari i ētahi wā ka pā ki ngā ringa me ngā ringaringa. Anei ō kare ā-roto ina pāngia koe e tēnei mate:

• ngoikore
• Te wiri
• te ngoikore
• Te ahua o te werowero / te ngira
• Te mura o te ngākau

Organomegaly - te whakanui ake i ngā whekau o roto

Mā ngā tikanga whakaahua e mahia ana e ngā tākuta ka kitea mēnā kua rahi ēnei whekau:

• Ate (Ate - `(Hepatomegaly)`)
• Te Wheke (Splenomegaly)
• Ngā Pūnaha Lymph (Ngā Pūnaha Lymph - `(Lymphadenopathy)`)

Endocrinopathy - he raruraru homoni

Ko te raruraru homoni matua e pā ana ki te POEMS ko te hekenga o te taumata o ngā homoni ira tangata. Ko ēnei homoni ira tangata e kiia ana ko te "Testosterone" i roto i ngā tāne, ā, ko te "Estrogen" i roto i ngā wāhine. Hei tāpiri, tera pea ka kite koe i ngā tohu pēnei i:

• Ngā raruraru ki te whakahaere i ngā taumata huka toto (hei tauira, te mate huka)
• Ngā raruraru o te tairoi (hei tauira, te Hypothyroidism)
• Te mate a Addison (Te ngoikore o te adrenal - `(Te mate a Addison)`)

Tērā pea ka pāngia ngā tāne e te ngoikore o te momonatanga me te whakanui i ngā ū (Gynecomastia).

Mō ngā wāhine , ka mutu pea te paheketanga (`(Amenorrhea)`), ka rahi pea ngā ū. I te wā e hapu ana, ka nui rawa te whakaputanga o te homoni `(Prolactin)`, e āwhina ana ki te whakaputa waiū. Nō reira, ka taea e te waiū te turuturu mai i ngā uma ahakoa kāore koe e hapu ana.

Te Pūmua-M kua Whakanuia

Ko tētahi āhuatanga matua o te POEMS ko te nui haere o te pūmua-M i roto i te toto. Ka taea e tēnei nui rawa o te pūmua-M te arahi ki te hanganga o ngā pukupuku i roto i te toto. Waihoki, nā te nui o te pūmua-M, kaKa matotoru, ka pakari hoki ngā wheua (osteosclerosis) .

Ngā huringa kiri

Ka puta pea ngā huringa kiri maha, pērā i:

• Kiri pouri ake
• Kiri matotoru ake
• Ngā maikuku mā
• Te tipu haere o ngā huruhuru i tō mata me ō waewae
• Te tipu o ngā oko toto e rite ana ki ngā cheri iti i runga i te kiri o te uma

Ētahi atu tohu

Hei tāpiritanga ki tēnei, ka kitea pea ētahi atu tohu:

• Te pupuhi o ngā ringa me ngā waewae
• Te ngaronga taumaha mō te kore take
• Te mamae o ngā wheua me ngā hononga
• Ngā ngoikoretanga tirohanga
• Te uaua ki te manawa
• Ngenge
• Kirika

Tērā pea kei ētahi tāngata whai mate POEMS tētahi āhuatanga e kiia nei ko te Mate Castleman (CD), e pā ana ki ngā pona lymph. Mena kei a koe ngā tohu o te Mate Castleman, tera pea ka whakapae tō tākuta kei a koe te POEMS.

He aha ngā pūtake o te mate POEMS?

Ina pāngia koe e te POEMS, ka pāngia koe e ngā momo tohu me ngā pānga nā te mate pūtau plasma monoclonal . He māmā noa iho, he nui rawa ngā tārua o tētahi pūtau plasma rerekē. Ka nui ake ēnei pūtau, ka nui ake te kino ka pā ki ngā kiko. Ka tāpirihia e ēnei pūtau te pūmua-M ki te toto, ka piki ake te nui o te pūmua-M i roto i te toto. Ko ēnei pūtau taikaha me te pūmua-M e kino ana i ngā pūnaha rerekē o te tinana.

Heoi anō, kāore anō kia tino mōhiotia e ngā kaipūtaiao he aha i tīmata ai te tipu rerekē o ēnei pūtau plasma.

Kua kitea e ngā kairangahau he pūmua e kiia nei ko te Vascular Endothelial Growth Factor (VEGF) pea kei roto. Ko te nuinga o te hunga e pāngia ana e te mate POEMS he nui ngā taumata o te VEGF i roto i ō rātou toto. Kei te haere tonu ngā rangahau mō te whanaungatanga i waenga i te VEGF me te mate POEMS.

Me pēhea te tātaritanga o te mate POEMS? (Tauātanga)

Ka pātai tuatahi tō tākuta ki a koe mō tō hītori hauora me ngā tohumate o nāianei. Kātahi ka whakahaerehia he whakamātautau tinana hei tirotiro i ngā tohu o te mate POEMS.

Hei tāpiri, ka taea e te tākuta te whakahaere i ētahi whakamātautau maha, pēnei i:

• Ngā whakamātautau toto me te mimi: Ka āwhina ēnei whakamātautau ki te tirotiro i ngā taumata teitei o te pūmua-M, o te VEGF rānei i roto i tō toto, i tō mimi rānei. Ka taea hoki e rātou te tirotiro i ngā tau toto rerekē, ngā pūtau toto āhua rerekē rānei. He tohu pea ēnei o te POEMS.
• Ngā whakamātautau whakaahua: Ka taea e ngā whakamātautau pēnei i ngā hihi-X me ngā karapa CT te whakaatu mēnā he matotoru, he pakari rānei ō wheua. Ka puta pea ēnei huringa ina teitei ake ngā taumata pūmua-M.
• Kohikohi ira wheua: Mā tēnei ka kitea mēnā he āhua rerekē ngā pūtau plasma kei roto i tō hinu wheua, mēnā rānei he nui rawa te maha o ngā pūtau plasma.
• Electromyogram (EMG): He whakamātautau te EMG e ine ana i te mahi a ngā io. Ka taea e ia te āwhina i tō tākuta ki te tautuhi i te polyneuropathy.

I runga anō i ō tohumate, ka whakahaerehia pea e tō tākuta ētahi atu whakamātautau, pērā i ngā whakamātautau manawa, ngā echocardiogram, ngā whakamātautau endocrine rānei.

Mena kua tāpaetia koe kei te pāngia e te mate e kiia nei ko te Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) , ka whakamatautauria pea koe e tō tākuta kia kitea ai mēnā kei a koe te mate POEMS.

Me pēhea te whakahaere, te rongoā rānei i te mate POEMS?

Kāore he rongoā mō te mate POEMS. Heoi anō, ka taea e ngā maimoatanga te āwhina ki te whakahaere me te whakahaere i ngā tohu. Ko ngā kōwhiringa maimoatanga ko:

• Whakaora irahiko: Kei roto i tēnei ko te tuku i ngā taumata teitei o te irahiko ki ngā pūtau plasma rerekē hei whakangaro i a rātou.
• Te rongoā matepukupuku: Ko ngā rongoā ārai matepukupuku, e mōhiotia ana ko te "Te rongoā matepukupuku", ka whakamahia hei whakamate, hei whakaroa rānei i te tipu o ngā pūtau toto rerekē. He rite te rongoā matepukupuku mō te POEMS ki te rongoā mō te myeloma maha. He tino whai hua ēnei rongoā, ā, he maha ngā wā kāore e puta he pānga kino kino.
• Te whakawhitinga pūtau take aunoa: Ka whakakapia e tēnei tikanga ō pūtau plasma rerekē ki ngā pūtau take hauora. Ko ngā pūtau take ko ngā pūtau e whanake ana hei pūtau pakeke pērā i ngā pūtau plasma. I roto i tēnei whakawhitinga, ka tangohia tuatahitia e tō tākuta ētahi pūtau take hauora mai i tō tinana. Kātahi ka whakamahia e rātou te chemotherapy, te radiation therapy rānei hei whakangaro i ngā pūtau plasma rerekē. Whai muri i te maimoatanga, ka whakahokia ngā pūtau take kua tangohia ki roto i tō tinana. Kātahi ka tipu hei pūtau plasma hauora.
• Whakaora tinana: Mena he uaua ki te hikoi nā te polyneuropathy, tera pea ka āwhina tēnei maimoatanga.

Hei tāpiritanga, ka tohua pea e te tākuta ngā rongoā pēnei i te steroids hei whakamamae i ngā tohu me ngā diuretics (ngā pire wai) hei whakaiti i te pupuhi.

He aha ngā raruraru e pā ana ki te mate POEMS?

I roto i te mate POEMS, ka piki haere te kino me te ngoikore o ngā io i roto i te wā. Ka uaua hoki te neke haere. Ki te nui rawa te wai e kohia ana i te taha o ngā pukahukahu, i roto rānei i te uma, ka mamae te uma, ka uaua hoki te manawa.

Engari kia mahara,Mā te maimoatanga angitu ka taea te aukati, te whakaroa rānei i te kino o ngā io. Ka taea hoki e ia te āwhina ki te whakamamae i ētahi atu tohu. Ahakoa te kino o ngā io ka taea te whakaora mārire i roto i te wā.

He āhuatanga mōrearea kei te pā mai o te mate POEMS?

Kāore anō kia kitea he āhuatanga mōrearea e pā ana ki te whakawhanaketanga o te mate POEMS i tēnei wā.

Ka taea te ārai i te mate POEMS?

Engari, kāore e taea te ārai i te mate POEMS.

He aha te āhua o te mate mō te hunga e pāngia ana e te mate POEMS?

He maha ngā āhuatanga e whakawhirinaki ana tō hauora, tae atu ki ngā wāhanga o tō tinana e pāngia ana, te tere o te tautuhi i te mate me te tīmatanga o te maimoatanga, me te āhua o tō urupare ki te maimoatanga.

He mea nui kia whiwhi maimoatanga mō te POEMS. Ka taea e te mate POEMS te whakararuraru i te ora mēnā kāore e rongoatia. I tētahi atu taha, mā ngā maimoatanga angitu e whakangaro ana i ngā pūtau plasma rerekē ka roa ake tō oranga. Hei tāpiri, ka taea e ngā maimoatanga te whakamamae i ngā tohu me te whakapai ake i te kounga o tō oranga.

Ko te toharite o te oranga mō te nuinga o te hunga whai POEMS he tata ki te 14 tau. Ko te tikanga, tata ki te haurua o te tangata e ora ana i raro iho i te 14 tau, ko te haurua ia e ora ana mō te roa ake. Ko tō roanga o te ora e whakawhirinaki ana ki tō wheako me tō maimoatanga.

Pātai atu ki tō tākuta mō tōu heke mai hei tangata e pāngia ana e te mate POEMS.

Āhea koe me toro atu ki te tākuta mō te mate POEMS?

Mena ka pāngia koe e ētahi tohu e pā ana ki te mate POEMS, inā koa te ngoikore o ngā ringa me ngā waewae , me toro atu ki te tākuta tonu.

He aha ngā pātai me pātai atu ki taku tākuta mō te mate POEMS?

Ka taea e koe te pātai i ngā pātai penei:

• He pēhea te kino o tōku āhua?
• He aha ngā kōwhiringa maimoatanga kei a au?
• Me aha ahau hei whakaiti, hei whakahaere rānei i ngā pānga taha?
• He aha ngā ratonga tautoko e wātea ana ki ahau?
• Me toro atu ahau ki tētahi tākuta tohunga ki ngā mate pūtau toto hei ārahi i taku maimoatanga?

Āhea ahau ka taea ai te hoki ki aku mahi o ia rā mēnā kei a au te mate POEMS?

Ka pāngia pea koe e te mate POEMS ki te mahi i ō mahi o ia rā. Ma tō tākuta koe e whakamārama me pēhea te pānga o tēnei mate ki tō oranga o ia rā.

He mate pūnaha ārai mate te mate POEMS?

He mate paraneoplastic te POEMS.Ehara i te mate pūnaha ārai mate. Ko te paraneoplastic syndrome he kohinga tohu e puta mai ana i tētahi mate hauora. I roto i te POEMS, ko te raruraru matua ko te nui rawa o te M-protein e whakaputaina ana e ngā pūtau plasma rerekē i roto i te toto (he mate pūtau plasma monoclonal). Ko ngā tohu o te POEMS e puta mai ana i ngā pūtau plasma rerekē me te M-protein e kino ana i ngā kiko o te tinana.

He rite tonu te mate POEMS ki te mate myeloma maha?

He mate pukupuku te myeloma maha e pā ana ki ngā pūtau plasma. Ko te mate POEMS he kohinga tohu e puta mai ana i ngā pūtau plasma rerekē me te pikinga o te pūmua-M. He pai ake te tere ora o te mate POEMS i te roanga o te oranga o te myeloma maha.

Heoi, he rite tonu ngā maimoatanga chemotherapy mō te POEMS me te myeloma maha. Tērā pea he rite anō hoki ētahi o ngā tohu.

He tātaritanga uaua te mate POEMS. Tērā pea ka roa te wā e whakatau ai tō tākuta mēnā ko te mate POEMS te take o ō tohumate, ehara i te mea nā tētahi atu mate. Kia oti koe te tātaritanga, mahi tahi me tō tīma hauora ki te whakatau ko ēhea maimoatanga ka tino whakaora i ō tohumate. Pātai atu ki tō tākuta mō ngā whakahaere, ngā rōpū tautoko rānei e āwhina ana i ngā tāngata takitahi me ngā whānau ki te whakatau i ngā tātaritanga pēnei i te mate POEMS.

Karere Tangohia ki te Kāinga

Āe, kua maha ā tātou kōrero mō te POEMS Syndrome i tēnei rā. Ko te mea nui kia mārama he mate onge tēnei, engari he mate kino . Ka pā pea ki ngā pūnaha maha o tō tātou tinana.

• I ahu mai te ingoa POEMS i ngā reta tuatahi o ngā ingoa Ingarihi o ngā tohu matua e rima (ngā mate io, te whakanui ake i ngā whekau o roto, ngā raruraru homoni, te pikinga o te pūmua-M, me ngā huringa kiri).
• Ko te tino take o tēnei ko ngā pūtau plasma rerekē me te pūmua-M e whakaputaina ana e rātou.
• Ahakoa kāore he rongoā katoa, kei reira ngā maimoatanga whai hua hei whakahaere i ngā tohu me te whakapai ake i te kounga o te oranga.
• He mea tino nui te tautuhi i te mate me te tīmata wawe i te maimoatanga .

Mena kei a koe ētahi o ēnei tohu, rapua he tohutohu hauora. Kaua e mataku, mā te mōhiotanga tika me te tautoko hauora, ka taea e koe te whakatau i tēnei āhuatanga.

` Te mate POEMS, ngā mate toto, te kino o ngā io, ngā raruraru homoni, te pūmua-M, ngā huringa kiri, ngā pūtau plasma