Celexa ndi Lexapro: Kodi pali kusiyana kotani pakati pa mankhwala awiriwa? (Citalopram ndi Escitalopram)

Kodi dokotala wanu anakupatsani mankhwala a matenda monga kuvutika maganizo kapena nkhawa? Ngati ndi choncho, mwina munamvapo za mankhwala otchedwa `Celexa` kapena `Lexapro`. Awa ndi awiri mwa mankhwala omwe amaperekedwa kwambiri pa matenda amenewa padziko lonse lapansi komanso m'dziko lathu. Chifukwa chake, funso lomwe anthu ambiri ali nalo ndi lakuti kodi pali kusiyana kotani pakati pa awiriwa, kodi ndi ofanana, ndipo ndi uti woyenera kwa ine? Tiyeni tikambirane za izi lero kuti tithetse kukayikira konse komwe muli nako m'maganizo mwanu.

Choyamba, tiyeni tiwone zomwe Celexa ndi Lexapro ali.

Mwachidule, mankhwala onsewa ali m'gulu lotchedwa antidepressants . Kunena zoona, amachokera ku gulu linalake la mankhwala lotchedwa ``SSRIs`` (Selective Serotonin Reuptake Inhibitors). Ngakhale dzinalo lingamveke ngati lovuta pang'ono, njira yake ndi yosavuta.

Tangoganizani kuti pali amithenga mkati mwa ubongo wathu omwe amanyamula uthenga mobwerezabwereza. Timawatcha amithengawa kuti ma neurotransmitters. Serotonin ndi mthenga wofunika kwambiri amene amalamulira zinthu monga momwe timamvera, khalidwe lathu, ndi kukumbukira. Mu matenda monga kuvutika maganizo, kuchuluka kwa Serotonin kumeneku kumatha kuchepa.

Zimene ma SSRI amachita ndikuletsa serotonin iyi kuti isatengedwenso mwachangu ikatha. Kenako serotonin imakhalabe m'maselo a mitsempha ya ubongo kwa nthawi yayitali. Izi zikutanthauza kuti uthenga "wachimwemwe" umakhalabe wogwira ntchito kwa nthawi yayitali. Apa ndi pamene malingaliro athu amayamba kusintha.

Celexa ndi dzina la mankhwala otchedwa Citalopram . Lexapro ndi dzina la mankhwala otchedwa Escitalopram . Onsewa ndi ovomerezeka kuchiza matenda aakulu ovutika maganizo (MDD) mwa akuluakulu, pomwe Lexapro ndi ovomerezekanso kuchiza matenda ovutika maganizo (GAD).

Chabwino, ndiye kusiyana kwakukulu pakati pa ziwirizi ndi kotani?

Ichi ndi chowonadi chosangalatsa kwambiri. `Citalopram` (Celexa) ndi `Escitalopram` (Lexapro), ponena za mankhwala, ndi zithunzi zofanana za molekyulu yomweyo. Monga momwe dzanja lathu lamanzere ndi dzanja lathu lamanja. Onse ndi manja, koma ndi osiyana. Mu chemistry, awa amatchedwa `enantiomers`.

• Citalopram (Celexa) ndi kuphatikiza kwa mitundu ya "amanja amanzere" ndi "amanja amanja" omwe mwatchulawa.
• Escitalopram (Lexapro) ndiye mankhwala ogwiritsidwa ntchito kwambiri kuposa awiriwa, zomwe zikutanthauza kuti ndi mankhwala opangidwa kuchokera ku gawo lalikulu lokha, monga "dzanja lamanja".

Ichi ndichifukwa chake pali kusiyana pang'ono pa momwe mankhwala awiriwa amagwirira ntchito m'thupi lathu.

Tiyeni tiwone kusiyana kwakukulu:

• Kugwiritsa Ntchito Kovomerezeka: Ngakhale kuti `Citalopram` imavomerezedwa kokha pa matenda a maganizo mwa akuluakulu, `Escitalopram` imavomerezedwa pa matenda a maganizo mwa akuluakulu ndi ana opitirira zaka 12, komanso pa matenda a nkhawa mwa akuluakulu ndi ana opitirira zaka 7.
• Kugwira Ntchito: Kafukufuku wina wasonyeza kuti Escitalopram ndi yothandiza pang'ono kuposa Citalopram poletsa zizindikiro za kuvutika maganizo.
• Chiwopsezo cha kugunda kwa mtima: Mankhwala onsewa akhoza kukhala ndi zotsatira zochepa pa ntchito yamagetsi ya mtima. Izi zimatchedwa `QT prolongation`. Izi zimakhala ndi chiopsezo chochepa cha kugunda kwa mtima kosazolowereka. Komabe, chiopsezochi chimakhala chachikulu pang'ono ndi `Citalopram` kuposa ndi `Escitalopram`, makamaka pamlingo wokwera.

Zotsatirapo zake ndi zinthu zomwe muyenera kuzidziwa

Popeza mankhwala onsewa ali m'banja limodzi, zotsatira zake zimakhala zofanana kwambiri. Si aliyense amene amalandira mankhwalawa, koma nthawi zambiri amatha pakatha masiku angapo thupi likayamba kuzolowera mankhwalawo.

'Serotonin Syndrome' ndi vuto lomwe limafuna chisamaliro chapadera.

Ichi ndi chinthu chomwe muyenera kudziwa . Serotonin Syndrome ndi kuchuluka kwa serotonin m'thupi komwe kumakhala koopsa kwambiri. Izi zimachitika nthawi zambiri mukayamba kumwa mankhwalawo, mukawonjezera mlingo, kapena mukamwa limodzi ndi mankhwala ena omwe amakhudza kuchuluka kwa serotonin (monga mankhwala ena a mutu waching'alang'ala, mankhwala ena oletsa kupsinjika maganizo).

Ngati inu kapena munthu amene mumamudziwa akukumana ndi zizindikirozi nthawi imodzi, pitani ku Dipatimenti Yothandiza Anthu Odwala Mwadzidzidzi (ETU) ya chipatala nthawi yomweyo.

• Kusakhazikika, kusakhazikika
• Kusanza, kutsegula m'mimba, kusanza
• Ophunzira otambasuka
• Kunjenjemera, kugwedezeka kwa minofu, kuuma
• Kutuluka thukuta kwambiri, kuzizira, ndi kunjenjemera
• Kusokonezeka kwakukulu, kutaya chidziwitso
• Kuthamanga kwa mtima, kuthamanga kwa magazi
• Malungo, khunyu, kutaya chidziwitso

Dziwani maganizo ofuna kudzipha.

Izi ndizofunikira kwambiri. Chiwopsezo cha maganizo ofuna kudzipha chingawonjezeke pang'ono m'masabata oyamba oyamba kumwa mankhwala ochepetsa nkhawa kapena posintha mlingo, makamaka kwa achinyamata ndi ana osakwana zaka 24. Dziwani bwino zizindikiro zotsatirazi.

• Kuvutika maganizo kukukulirakulira.
• Kuganiza zothetsa moyo wanu.
• Kuukira ndi mantha.
• Kusowa tulo.
• Kusakhazikika, kukwiya, kukwiya.
• Kuchita zinthu popanda kuganiza ndikukhala ndi chisangalalo chosaneneka.

Kodi mungakhale ndi chizolowezi cha mankhwalawa?

Ayi. Izi sizimaonedwa ngati mankhwala osokoneza bongo monga mankhwala osokoneza bongo. Komabe, pali vuto.Ngati mwadzidzidzi musiya kumwa mankhwalawa kwa milungu yoposa 6, mutha kumva kusasangalala kwakuthupi. Izi zimatchedwa `antidepressant discontinuation syndrome`. Zizindikiro monga kusintha kwa malingaliro, chizungulire, ndi nkhawa zimatha kuchitika.

Choncho, musasiye kumwa mankhwalawa mwadzidzidzi popanda kufunsa dokotala wanu. Kusiya kuyenera kuchitika motsatira malangizo a dokotala wanu, mwa kuchepetsa pang'onopang'ono mlingo.

Ntchito zina za Celexa ndi Lexapro (Ntchito zopanda chizindikiro)

"Kugwiritsa ntchito mankhwala osakhala ndi chizindikiro" kumatanthauza kupereka mankhwala pa vuto lomwe silinavomerezedwe mwalamulo pa vuto limenelo, koma madokotala amadziwa kuchokera pa zomwe akumana nazo kuti mankhwalawa ndi othandiza pa vuto limenelo. Mankhwala onsewa amagwiritsidwa ntchito pa matenda ena angapo, kuphatikizapo:

• Nthawi zina pamene Citalopram (Celexa) ingagwiritsidwe ntchito:
• Matenda Ovutika Kwambiri (OCD)
• Matenda a Mantha
• Matenda a Nkhawa Pagulu
• Matenda ovutika maganizo pambuyo pa zoopsa (PTSD)
• Kutulutsa umuna msanga

• Nthawi zina pamene Escitalopram (Lexapro) ingagwiritsidwe ntchito:
• Matenda a Nkhawa Pagulu
• Matenda okakamiza kwambiri (OCD)
• Matenda a Mantha
• Zizindikiro zokhudzana ndi kusamba (monga kutentha thupi)

Ndiye, ndi iti yomwe mungasankhe pakati pa ziwirizi?

Funso lofunika kwambiri ndi ili. Ichi ndi chisankho chomwe dokotala wanu adzapanga atatha kukufufuzani ndi kuganizira zinthu zambiri, monga zizindikiro zanu, zaka zanu, ndi matenda ena.

• Ngati muli ndi nkhawa komanso kuvutika maganizo, Lexapro ikhoza kukhala chisankho chabwino.
• Ngati muli ndi mbiri ya matenda a mtima, Lexapro ikhoza kukhala njira yabwino chifukwa ili ndi zoopsa zochepa.
• Kwa anthu ena, `Celexa` imagwira ntchito bwino. Kwa ena, `Lexapro` ndi yoyenera kwambiri.