Kodi pali mbiri ya banja lanu yomwe inadwalapo khansa? Tiyeni tiphunzire za Lynch Syndrome

Nthawi zina timadzifunsa kuti, "Ndili ndi mbiri ya khansa m'banja langa, choncho ndimadabwa ngati inenso ndili ndi mwayi woti ndiipezenso." Ndipotu, mitundu ina ya khansa ingayambitsidwe ndi majini omwe amapatsirana kuchokera ku mibadwomibadwo. Mwachitsanzo, Lynch Syndrome ndi matenda omwe amawonjezera kwambiri chiopsezo cha khansa, koma samakambidwa kwambiri. Ndikofunikira kwambiri kudziwa izi. Choncho tiyeni tikambirane za izi lero.

Mwachidule, kodi Lynch Syndrome ndi chiyani?

Matenda a Lynch ndi matenda a majini omwe amapatsirana kuchokera kwa kholo kupita kwa mwana, kapena cholowa . Munthu amene ali ndi vutoli ali pachiwopsezo chachikulu, kapena ali pachiwopsezo chachikulu, chotenga mitundu ina ya khansa kuposa ena.

Makamaka, munthu amene ali ndi vutoli amakhala ndi mwayi waukulu wa 40% mpaka 80% wokhala ndi khansa ya m'matumbo akamafika zaka 70. Palinso chiopsezo chachikulu cha khansa ya m'chiberekero, mazira, ndi m'mimba. Chodabwitsa pa izi ndichakuti khansa imatha kukula msanga kuposa msinkhu wabwinobwino wa khansa, mwina m'zaka za m'ma 30 kapena 40.

Kodi chifukwa cha vutoli n'chiyani?

Kuti timvetse izi, tiyeni tiganizire za matupi athu kwakanthawi. Matupi athu amapangidwa ndi maselo mabiliyoni ambiri. Maselo amenewa nthawi zonse amagawikana ndikupanga maselo atsopano. Taganizirani ngati kupanga makope pogwiritsa ntchito makina ojambulira. Maselo akagawikana motere, nthawi zina zolakwika zazing'ono zimachitika. Koma mwamwayi, DNA ya thupi lathu ili ndi majini apadera oti 'asagwirizane' omwe amazindikira zolakwikazi ndikuzikonza.

Munthu amene ali ndi matenda a Lynch syndrome amakhala ndi vuto kapena cholakwika mu imodzi mwa majini amenewa . Kenako, maselowo akamagawikana, zolakwika zina sizimakonzedwa, ndipo maselo olakwikawo amapitiriza kugawikana, ndipo maselo ena ambiri olakwika amayamba kupangika m'thupi. Pakapita nthawi, maselo olakwikawa amakhala khansa.

Ngati amayi kapena abambo anu ali ndi vutoli, muli ndi mwayi wa 50% wolandiranso matendawa.

Kodi zizindikiro zomwe zingayambitse matenda a Lynch ndi ziti?

Pali mfundo zingapo zofunika zomwe zingakupangitseni kuda nkhawa ndi vutoli. Ngati chimodzi mwa izi chikukhudza inu kapena banja lanu, ndikofunikira kwambiri kulankhula ndi dokotala.

Kodi mungazindikire bwanji vutoli?

Ngati inu kapena wina m'banja mwanu mwadwala khansa ndipo dokotala wanu akukayikira kuti mwina ndi chifukwa cha matenda a Lynch, chitsanzo chochepa cha khansa chingayesedwe. Pali njira ziwiri zazikulu zochitira izi:

• Mayeso a Immunohistochemistry (IHC): Mayeso awa a mitundu ya mapuloteni omwe amapezeka m'maselo a khansa. Ngati mapuloteni opangidwa ndi 'majini oyesera' omwe tidakambirana kale sapezeka m'maselo amenewo, akhoza kukhala chizindikiro cha matenda a Lynch.
• Kuyesa kwa Microsatellite instability (MSI): Izi zimayang'ana mwachindunji zolakwika mu DNA ya maselo a khansa.

Ngati mayesowa akutsimikizira kuti muli ndi matenda a Lynch, kapena ngati mukuganiza kuti muli pachiwopsezo chifukwa chakuti wina m'banja mwanu ali ndi vutoli, mutha kuyesedwa majini pamagazi kuti mudziwe ngati muli ndi vuto la majini.

Chithandizo kuchokera kwa Mlangizi wa Majini

Pa nthawiyi, dokotala wanu angakutumizireni kwa katswiri wa majini. Adzakufotokozerani zambiri zokhudza izi.

• Momwe matenda a Lynch amabadwira m'banja.
• Kodi zotsatira za lipoti lanu la mayeso a majini zikutanthauza chiyani?
• Momwe zotsatirazi zimakhudzira chiopsezo chanu cha khansa.
• Mwayi woti ana anu adzalandira jini iyi kuchokera kwa inu.
• Njira zomwe mungasankhe kuti mupewe khansa.

Ngati muli ndi matenda a Lynch, kodi amathandizidwa bwanji?

Chinthu chabwino kwambiri choti muchite mukadziwa kuti muli ndi vutoli ndikupita kukayezetsa khansa nthawi zonse . Komabe, ngakhale khansa itayamba, nthawi zambiri imapezeka msanga kwambiri ndipo imatha kuchira kwathunthu . Mwachitsanzo, khansa ya m'matumbo imatha kuchiritsidwa mu 90% ya milandu ngati yapezeka msanga.

Dokotala wanu adzasankha mayeso omwe muyenera kuchita komanso nthawi yomwe mungafunikire. Mayeso omwe nthawi zambiri amalimbikitsidwa ndi awa:

• Kuyeza kwa Colonoscopies: Kuyambira ndili ndi zaka 20-25, mungapemphedwe kuti muchite mayesowa chaka chilichonse kapena ziwiri. Izi zimayang'ana ngati pali ma polyps kapena zizindikiro za khansa m'matumbo akulu.
• Endoscopy: Kuyambira muzaka za m'ma 30, izi zitha kuchitika zaka 3-5 zilizonse kuti mufufuze m'mimba ndi matumbo.
• Mayeso a akazi: Pambuyo pa zaka 30, mayeso monga mayeso a m'chiuno, ultrasound ya transvaginal, kapena biopsy ya uterine angalimbikitsidwe chaka chilichonse kuti aone chiberekero ndi mazira.

Anthu ena, makamaka amayi omwe adaberekapo ana, amalankhula ndi dokotala wawo za opaleshoni yopewera khansa. Izi zikutanthauza kuchotsa m'matumbo, chiberekero, kapena mazira asanayambe khansa. Ichi ndi chisankho chaumwini.

Kufunika kwa moyo wathanzi

Ngakhale kuti amapimidwa nthawi zonse, kukhala ndi moyo wathanzi kumathandizanso kuchepetsa chiopsezochi.

• Idyani zakudya zokhala ndi ndiwo zamasamba zambiri, zipatso, nyemba, ndi tirigu wonse.
• Chitani masewera olimbitsa thupi nthawi zonse .
• Lamulirani kulemera kwanu.
• Chepetsani kumwa mowa.

Kafukufuku wina wasonyeza kuti kumwa aspirin yochepa tsiku lililonse kungachepetse chiopsezochi, koma kafukufuku wowonjezereka akufunika pankhaniyi. Chifukwa chake , musayambe kumwa mankhwala nokha popanda kufunsa dokotala wanu.