Auvelity ni iki? Ikora ite?
Mu magambo make, 'Auvelity' ni uruvange rw'imiti ibiri. Ibyo bivuze ko hari ubwoko bubiri bw'imiti mu kinini kimwe. Ni 'dextromethorphan' na 'bupropion'. Tekereza ko ari ugukorana nk'ikipe. Abantu babiri bakorana bakora imiti irenze umwe bonyine.- Bupropion : Uyu ni umuti usanzwe ukoreshwa mu kuvura indwara yo kwiheba . Ukora mu kongera urugero rw'ibinyabutabire mu bwonko bwacu byitwa `dopamine` na `norepinephrine`, bigira ingaruka ku byiyumvo byacu.
- Dextromethorphan : Ushobora kuba uzi iyi sirupe imwe n'imwe ikoresha inkorora irimo uyu muti. Ariko, uyu muti wagaragaye ko ugira ingaruka ku bintu bifitanye isano n'ibyiyumvo mu bwonko.
Ni gute intsinzi y'uyu muti yageragejwe?
Mbere yo guha abantu umuti uwo ari wo wose, babanza gusuzuma uburyo ufite umutekano n'ubushobozi. Hari ubushakashatsi bubiri nk'ubwo bwakorewe kuri 'Auvelity'. Muri ubu buryo, hakoreshejwe uburyo bwihariye bwo gupima ubukana bw'indwara yo kwiheba. Byitwa ``Montgomery-Asberg Depression Rating Scale (MADRS).`` Ni nk'urupapuro rw'ibibazo. Ubazwa ibibazo 10 ku bintu nk'agahinda, ibibazo byo gusinzira, no kumva wicira urubanza, maze uhabwa amanota. Ushobora gutanga amanota kuva kuri 0 kugeza kuri 60. Uko amanota aba menshi, niko urushaho kwiheba. Kugabanuka kw'amanota nyuma yo gufata umuti bivuze ko indwara igenda irushaho koroha. Ubu bushakashatsi bwari bukubiyemo abantu bari hagati y'imyaka 18-65 bafite indwara yo kwiheba gukomeye. Ariko, abantu bafite izindi ndwara zo mu mutwe (nk'indwara yo mu mutwe ihindagurika ry'ibihaha, indwara yo mu mutwe ihindagurika ry'ibihaha), abantu bafite ibyago byinshi byo kwiyahura, n'abantu bafite igicuri ntibashyizwemo.Ni ibihe bisubizo by'ubushakashatsi?
Ibisubizo birashimishije cyane. Umuti `Auvelity` wagize akamaro kanini mu kugabanya ibimenyetso by'indwara yo kwiheba kurusha placebo na `bupropion` byonyine. Ibi bivuze ko amanota `MADRS` yari make ku bafata `Auvelity` kurusha ku bafata indi miti.| Ugereranije n'umuti | Impuzandengo y'igabanuka ry'amanota ya MADRS nyuma y'ibyumweru 6 |
|---|---|
| Ubuhanga | Ku manota 16 |
| Placebo | Ku manota 12 |
| Ubuhanga | Ku manota 14 |
| Bupropion gusa | Ku manota 9 |
Ese Auvelity ishobora kugira ingaruka ku yindi miti? (Imikoreshereze y'imiti)
Iki ni ingenzi cyane . Yego, Auvelity ishobora kugira ingaruka ku yindi miti ufata. Rero, ugomba kubwira muganga wawe imiti yose ufata, harimo imiti igurishwa mu kigo, vitamine, ndetse n'imiti ya Ayurvedic.Indwara iteje akaga yitwa Serotonin Syndrome
Iyo Auvelity ifashwe hamwe n'indi miti igabanya ubukana bw'indwara zo mu mutwe yongera urugero rwa serotonin, ishobora gutera kwiyongera ku buryo butunguranye kwa serotonin mu bwonko. Ibi byitwa Serotonin Syndrome. Iki ni ikibazo gihangayikishije ubuzima.Ibimenyetso: Kubira ibyuya byinshi , umuriro, kubura amahoro , umutima utera cyane, isesemi, kuruka , impiswi, gucika intege, imitsi ikomeye cyangwa gutitira.
Izindi ngaruka
- Ku miti yongera dopamine: `Auvelity` yongera dopamine mu bwonko. Rero iyo ifashwe hamwe n'indi miti yongera dopamine (nk'imiti imwe n'imwe ivura indwara ya Parkinson), urugero rwa dopamine rushobora kwiyongera cyane, bigatera kubura amahoro, gutitira,Kugenda n'amaguru bishobora kugorana.
- Ku bijyanye n'inzoga: Kunywa inzoga bigomba kwirindwa cyangwa kugabanywa cyane mu gihe ufata `Auvelity`. Kuzinywa byombi byongera ibyago byo kurwara ibicurane .
- Imiti y'umutima: Ingufu z'imiti y'umutima nka digoxin zishobora guhinduka bitewe na Auvelity. Ni ngombwa kubimenyesha muganga wawe.
- Indi miti ivunjwa n'umwijima: Umwijima wacu umeze nk'uruganda ruvunjwa imiti. Ubuvuzi bugira ingaruka kuri sisitemu ya enzyme yitwa ``cytochrome P450 (CYP450)`` muri iyi sisitemu. Ibi bishobora guhindura uburyo indi miti ufata ikora.
Uyu muti ukoreshwa ute kandi ni izihe ngaruka mbi?
`Auvelity` ni umuti utangwa na muganga gusa. Igipimo gisanzwe ni ikinini kimwe ku munsi mu minsi itatu ya mbere, hanyuma ikinini kimwe kabiri ku munsi (amasaha 8 atandukanye).Umuburo: Ntuzigere uhindura ingano yatanzwe na muganga wawe cyangwa ngo uyihagarike mu buryo butunguranye.
Ingaruka mbi zishobora kubaho n'ibintu ugomba kwitondera
- Umuvuduko w'amaraso ukabije: Muganga wawe ashobora kukubwira ko ugomba kugenzura umuvuduko w'amaraso yawe buri gihe.
- Kuzungera: Uyu muti ushobora gutera isereri. Kubwibyo, witondere igihe utwaye imodoka, ukoresha imashini, ndetse no mu gihe ukora ibikorwa bishobora gutuma umuntu agwa.
- Ingaruka ku maso: Bwira muganga wawe niba ubabara amaso, ukagira umutuku, cyangwa ukagira impinduka mu maso.
- Impinduka mu myitwarire: Hari abantu bashobora kugira urujijo mu mutwe, kubona cyangwa kumva ibintu bitabaho (ibintu bitabaho), no kugorwa no kumenya ukuri.
- Indwara zo mu mutwe: Izi ngaruka ziyongera iyo unyoye inzoga. Niba ugize indwara zo mu mutwe uri gufata imiti, hagarika gufata imiti ako kanya kandi ubibwire muganga wawe.
- Ababyeyi batwite n'abonsa: Uyu muti ntabwo utekanye mu gihe utwite cyangwa wonsa. Niba uteganya gutwita, utwite, cyangwa wonsa, menyesha muganga wawe ako kanya.
Ubumenyi bwihariye ku bitekerezo byo kwiyahura
Kimwe n'imiti imwe n'imwe ivura ihungabana, Auvelity ishobora kongera gato ibyago byo gutekereza cyangwa gukora ibikorwa byo kwiyahura kuri bamwe, cyane cyane mu ntangiriro z'ubuvuzi.Ibi bikunze kugaragara cyane mu rubyiruko. Niba wowe cyangwa umuntu wo mu muryango wawe ufite ibi bitekerezo, ntukabe wenyine.- Hamagara 1926 (Umurongo w'Igihugu w'Ubufasha ku Buzima bwo mu Mutwe) ako kanya.
- Bitabaye ibyo, jya mu Ishami rishinzwe Ubuvuzi bwihutirwa (ETU) ry’ibitaro biri hafi yawe.
- Bibwire muganga wawe ibi ako kanya.
Ubutumwa bwo kujyana mu rugo
- `Auvelity` ni umuti ugezweho kandi ufite akamaro wo kuvura indwara yo kwiheba gukabije. Ariko, ugomba gufatwa gusa ku nama za muganga.
- Ni ingenzi cyane kubwira muganga wawe indi miti yose, vitamine, n'inyongeramusaruro ufata.
- Irinde inzoga burundu mu gihe ufata `Auvelity`.
- Menya ingaruka mbi nka serotonin syndrome, impinduka zikomeye mu myitwarire, cyangwa ibitekerezo byo kwiyahura. Niba ubonye kimwe muri ibi, shaka ubufasha kwa muganga byihutirwa.
- Ntukigere ufata imiti irenze urugero rwatanzwe cyangwa ngo uhagarike gufata imiti mu buryo butunguranye utabanje kugirwa inama na muganga.
👩🏽⚕️ Ibibazo by'inyongera (Ibibazo Bikunze Kubazwa)
💬 Ni iyihe ndwara Auvelity ikoreshwa mu kuvura?
Auvelity ni umuti mushya ku bantu bafite indwara ikomeye yo kwiheba (MDD). Usa n'ikinini kimwe, ariko urimo ubwoko bubiri bw'imiti, dextromethorphan na bupropion, bivanze.
💬 Ni iki gitandukanya ibi n'indi miti igabanya ubukana bw'indwara?
Imiti igabanya ububabare isanzwe imara ibyumweru 4 kugira ngo itangire gukora. Ariko inyungu nini ya Auvelity ni uko irushaho kuba nziza vuba, mu cyumweru kimwe uhereye igihe watangiye gufata imiti.
💬 Ni nde udakwiriye uyu muti?
Abaganga bavuga ko niba ufata imiti ya cholesterol cyangwa umuvuduko w'amaraso kandi ukaba waragize ibisebe udashobora gusubiza inyuma, gukoresha uyu muti si byiza.
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