Ese ukunze kugira allergie irimo utudomo dutukura no kwishimagura umubiri wose? Ibi bishobora kuba ari Mastocytosis!

Ese ukunze kugira ibibyimba bitukura, bikurura, ndetse rimwe na rimwe bikaba bikomeye ku mubiri wawe? Cyangwa se uhura n'ingaruka zikomeye ku kintu gito cyane umaze iminsi urwaye? Ushobora gutekereza uti "Ndimo kugira izindi ndwara ziterwa na allergie." Ariko, rimwe na rimwe inyuma y'ibi bimenyetso, hashobora kubaho indwara idakunze kugaragara tutarayumva. Imwe muri izo ndwara ni `(Mastocytosis)`. Nubwo izina rishobora kumvikana nk'iry'ibidasanzwe, reka tubiganireho mu buryo bworoshye.

Mastocytosis ni iki? Mu magambo make...

Tekereza, mu mibiri yacu harimo uturemangingo tumeze nk'abarinzi bato b'umutekano. Tutwita "uturemangingo twa mast." Utwo "uturemangingo twa mast" ni bimwe mu bigize "ubudahangarwa bw'umubiri" bwacu. Ni nk'ingabo z'umutekano z'igihugu cyacu. Iyo abanzi nka mikorobe, bagiteri, n'ibintu bitera allergie binjiye mu mubiri, utwo "turemangingo twa mast" turaza tukarwana.

Iyo izi `(mast cells)` zitabiriye abanzi, zirekura imiti yitwa `(histamine).` Iyi `(histamine)` ni yo itera ibimenyetso by'ubwivumbure mu mubiri wacu (urugero, kubyimba, gutukura k'uruhu, kubyimba). Izi `(mast cells)` zinafasha mu gukora aside mu gifu.

Ubusanzwe, izi `(mast cells)` zikora akazi kazo kandi zigategeka abanzi hanyuma zikongera guceceka. Ariko, ikiba mu mubiri w'umuntu ufite `(Mastocytosis)` ni uko izi `(mast cells)` ziyongera mu buryo budasanzwe kandi butunguranye. Iyo ziyongera gutya, izi selile zirekura `(histamine)` nyinshi cyane. Ni bwo uhura n'allergie ikomeye ndetse no ku kintu gito cyane, cyangwa iyo uhuye n'allergie, iba mbi kurusha iyo umuntu asanzwe, kandi iramba igihe kirekire.

Icy'ingenzi kurushaho, umuntu wese ufite Mastocytosis aba afite ibyago byinshi byo kurwara anaphylaxis , bikaba byamuviramo allergie itunguranye, ikomeye kandi ishobora no kumuhitana . Kubwibyo, ni ngombwa kubimenya.

Nubwo abaganga badashobora gukiza burundu indwara ya Mastocytosis, bashobora kugenzura ibimenyetso no kuvura ingorane zose zishobora kuvuka.

Ni ubuhe bwoko bw'ingenzi bwa Mastocytosis?

Hari ubwoko bubiri bw'ingenzi bw'iyi ndwara:

1. Guturika kw'amabere mu ruhu: Ibi bikunze kubaho mu bana bato n'abana bato . Ariko, bishobora no kubaho no mu bantu bakuru. Ikibaho hano ni uko "uturemangingo tw'amabere" tudasanzwe twirundanya mu ruhu, bigatuma habaho uduheri n'uduheri twinshi dutukura, umutuku wijimye, umukara, cyangwa amabara avanze. Ni nk'aho umwana muto ahita agira utudomo twinshi dutukura ku mubiri we kandi akadukubita ubudasiba.

2. Mastocytosis y’umubiri: Ubu bwoko bukunze kugaragara cyane ku bantu bakuru.Aha, "uturemangingo twa mast" tudasanzwe twikusanyiriza mu ngingo z'imbere nko mu musokoro w'amagufwa, mu magufwa, mu buryo bw'igogora, no mu bihaha. Tekereza, iyo utu turemangingo twikusanyije cyane mu musokoro w'amagufwa, bishobora kugira ingaruka ku miterere y'uturemangingo tw'amaraso yacu. Nanone, iyo utu turemangingo twiyongera mu gifu, dushobora gukora aside nyinshi mu gifu bigatuma habaho ibisebe mu gifu.

Ese iyi ni indwara isanzwe?

Oya, iyi ni indwara idasanzwe. Dukurikije ubushakashatsi, bivugwa ko umuntu umwe gusa mu bantu ibihumbi icumi (10.000) cyangwa umwe mu bantu ibihumbi makumyabiri (20.000) arwaye iyi ndwara. Kubwibyo, ni ibisanzwe ko atari buri wese uyizi.

Ni ibihe bimenyetso bishobora kugaragara ku ndwara ya Mastocytosis?

Uko izi "mast cells" ziyongera mu buryo budasanzwe, ibimenyetso bitandukanye bishobora kubaho. Nubwo ibi bimenyetso bishobora kuba byoroshye cyane kuri bamwe, bishobora no kuba bikomeye ku bandi.

• Kubabara amagufwa: Kumva nk'aho amagufwa yawe arimo kubabara.
• Kubabara mu gifu: Kujya mu bwiherero kenshi.
• Gucika intege (nk'ugutakaza ubwenge): Mu buryo butunguranye, amaso ahinduka ubururu maze usa n'aho utakaje ubwenge.
• Guhorana ubwoba n'ihungabana: Kumva uhangayitse nta mpamvu.
• Gushyuha: Guturika k'uruhu ku mubiri wose mu buryo butunguranye.
• Uduheri cyangwa ibizinga ku ruhu: Nkuko twabivuze mbere.
• Kuribwa umutwe: Kuribwa umutwe kenshi.
• Kuzungera biterwa n'umuvuduko w'amaraso uri hasi: Kumva uzungera iyo uhagaze uhagaze.
• Kubabara ingingo: Kubabara ingingo.
• Uduheri tw'umutuku cyangwa umukara ku ruhu: Ibi bishobora kuba bikurura cyangwa bitakurura.

Mastocytosis itangira ku kigero kingana iki?

Bihinduka bitewe n'ubwoko bw'indwara. Muri rusange:

• Gukira kw'amagufwa mu gituza: Ibi bishobora no kwibasira abana bavutse.
• Mastocytosis yo mu mubiri: Ikunze kwibasira abantu bakuru barengeje imyaka 50.

Impamvu ni iyihe?

`(Mastocytosis)` si ikintu tuvukana. Biterwa n'impinduka mu turemangingo twitwa `(KIT genes)`. Izi `(KIT genes)` ni jeni zifasha ubwoko bumwe na bumwe bw'uturemangingo, nk'uturemangingo tw'amaraso yacu, `(mast cells)`, gukura. Muri `(Mastocytosis), izi `(KIT genes)` zahinduwe zitanga ikimenyetso kitari cyo `(mast cells)` cyo "kwiyongera cyane no gukura mu buryo butunguranye."

Ni ibihe bintu bitera mastocytosis?

Ibi bishobora gutandukana bitewe n'umuntu ku giti cye. Si abantu bose bafite impamvu zimwe. Ariko, hari ibintu bimwe na bimwe bishobora kongera ibimenyetso muri rusange:

• Gukanda cyangwa gukanda uruhu: Ibi bishobora no kuba kuri bamwe iyo bambaye imyenda ibahasha gusa.
• Imyitozo ngororamubiri n'imyitozo ngororamubiri ikabije.
• Udukoko turuma cyangwa turuma:Cyane cyane inyamaswa nk'imisenyi, ivubi n'inzuki.
• Kunywa inzoga.
• Ibiryo bimwe na bimwe: Cyane cyane ibiryo birimo ibirungo byinshi kandi biryoshye cyane.
• Imiti imwe n'imwe: Urugero, imiti igabanya ububabare yitwa ``NSAIDs``` (imiti igabanya ubushyuhe itari iya steroide), imiti igabanya ububabare bw'imitsi, n'imiti igabanya ububabare ``(ikinya)```.
• Impinduka zitunguranye mu bushyuhe: Nk'aho umuntu asimbukira mu mazi akonje cyane.
• Imihangayiko y'umubiri cyangwa iyo mu mutwe: Ibi bikunze kugira ingaruka zikomeye.

Ni izihe ngorane zishobora guterwa na Mastocytosis?

Iyi ndwara ishobora gutera izindi ngorane z'ubuzima, harimo:

• Osteoporosis: Ibi bituma amagufwa acika intege kandi byoroshye kuvunika.
• Ibibazo by'umwijima: Indwara ituma umwijima ubyimba kandi ntukore neza.
• Cytopenia: Kudashobora gukora uturemangingo tw'amaraso duhagije mu mubiri.
• Kwandura indwara kenshi.

Ni gute Mastocytosis ipimwa?

Muganga wawe azabaza ibimenyetso byawe kandi asuzume uruhu rwawe. Byongeye kandi, bashobora gukora ibizamini nka:

• Ibipimo by'amaraso: Reba urugero rwa enzyme yitwa ``tryptase`` mu maraso yawe. Iyi ``tryptase`` ni ikintu ``uturemangingo twa mast``` dusohora iyo twitabiriye abanzi.
• Gusuzuma amagufwa: Kugira ngo harebwe niba amagufwa yangiritse.
• Isuzuma ry'umusemburo w'amagufwa: Hafatwa icyitegererezo cy'umusemburo w'amagufwa hanyuma hagasuzumwa uturemangingo tw'umusemburo tudasanzwe.
• Ibizamini bya Genetike: Niba ufite Systemic Mastocytosis, ushobora gupimwa impinduka mu ngirabuzimafatizo za KIT.

Ni ubuhe buryo bwo kuvura Mastocytosis?

Uburyo bwo kuvura buratandukanye bitewe n'ubwoko bw'indwara n'ibimenyetso byawe. Ubusanzwe abaganga bakoresha imiti n'ubundi buryo bwo kuvura kugira ngo bagabanye ibimenyetso.

Ubwoko bw'imiti ikoreshwa mu kuvura Mastocytosis:

• Antacids (H2 blockers) ku bibazo byo mu gifu: Ku bintu nko kubyimba mu gifu na gastritis.
• Antihistamines: Igabanya ibimenyetso by'uruhu birimo ubwivumbure nko kuribwa no gutukura.
• Bisphosphonates ivura indwara yo kubura amaraso: Ikomeza amagufwa.
• Corticosteroids: Igabanya kubyimba.
• Antibodies za monoclonal: cyane cyane imiti nka omalizumab (Xolair®).
• Imiti igabanya ububabare .

Ubundi buryo bwo kuvura:

• Ubuvuzi bw'urumuri rwa Ultraviolet (UV): Kugabanya ibizinga byijimye ku ruhu.
• Ubuvuzi bwibasiwe .
• Epinephrine ivura indwara ya anaphylaxis:Ubuvuzi bwihutirwa ku ndwara ikomeye ya ubwivumbure.
• Chimiotherapie: Iyi ni gake cyane kandi itangwa gusa iyo Mastocytosis ihindutse kanseri.
• Guteranya uturemangingo tw’umusemburo (umusemburo w’amagufwa): Ibi binafatwa mu bihe bikomeye cyane kandi bigoye cyane bya mastocytosis. Abantu benshi ntibabikeneye.

Ese hari ingorane cyangwa ingaruka mbi z'ubuvuzi?

Yego, kimwe no ku buvuzi ubwo aribwo bwose, hari ingaruka zimwe na zimwe zishobora kubaho mu kuvura Mastocytosis. Zimwe zishobora kuba ntoya, izindi zikaba zikomeye kurushaho. Niba ufite Mastocytosis, muganga wawe azagusobanurira uburyo bwo kuvura urimo guhabwa n'ingaruka mbi zishobora kubaho.

Ese Mastocytosis ishobora gukira burundu?

Muri rusange, Mastocytosis ifatwa nk'indwara idashobora gukira burundu, ariko ishobora gukemurwa no kugenzura ibimenyetso no kuvura ingorane .

Uburyo bwonyine bwo kuvura ibi ni uburyo bwo gutera uturemangingo tw’igufwa twavuzwe haruguru bwo "guteranya uturemangingo tw’igufwa" (allogeneic stem cell). Ariko, nubwo bimeze gutyo, ni byiza gusa ku barwayi bafite indwara zikomeye kandi zigoye cyane.

Ese Mastocytosis irushaho kwiyongera uko igihe kigenda gihita?

Iyo bitavuwe, ibimenyetso bishobora kwiyongera uko igihe kigenda gihita, cyane cyane ku muntu ufite mastocytosis , kuko uturemangingo tw’umusemburo tudasanzwe dukomeza kugira ingaruka ku musokoro w’amagufwa no ku ngingo z’imbere.

Ese Mastocytosis ishobora kwirindwa?

Ikibabaje ni uko atari byo. Kubera ko biterwa n'impinduka mu ngirabuzimafatizo za KIT, nta buryo bwo kubikumira. Ariko, niba ufite Mastocytosis, ushobora kugenzura ibimenyetso byawe umenye neza icyagutera allergie no kubyirinda uko bishoboka kose.

Urugero, niba ufite impamvu ituma ufata imiti imwe n'imwe, ni byiza kwambara umukandara wo kwa muganga ugaragaza iyo miti. Ibi bizamenyesha abandi imiti utagomba gufata mu gihe cy'impanuka.

Niba ufite indwara ya Systemic Mastocytosis, ni ngombwa guhora witwaje syringe yitera irimo epinephrine. Iyi syringe ishobora gukoreshwa mu kuvura indwara zikomeye zishobora gushyira ubuzima mu kaga nko kurwara indwara ya anaphylactic shock.

Niyitaho nte? (Mastocytosis) Mu gihe mbana na...

Kubera ko Mastocytosis ari indwara idashobora gukira burundu, ushobora kuyimarana igihe runaka. Ishobora kugorana. Ariko, dore ibintu bimwe na bimwe bishobora kugufasha:

• Menya neza icyagutera ibimenyetso.Ibintu bitera indwara biratandukanye. Ushobora kwandika mu ikaye yawe igihe ibimenyetso byawe byarushijeho gukomera, ibyo wariye n'ibyo wanyoye, n'ibyo wakoraga icyo gihe.
• Stress ishobora gutuma ibi bimenyetso birushaho kwiyongera. Niba ukeneye ubufasha mu gucunga stress, baza muganga wawe gahunda zo gucunga stress. Ibintu nka meditation na yoga bishobora gufasha.
• Ambara umukandara w'ubutabazi bw'abaganga. Ugomba kugaragaza uko ubuzima bwawe buhagaze n'imiti yose utagomba gufata.
• Jyana urushinge rwa epinephrine auto-injection. Rushobora kurokora ubuzima mu gihe habayeho ubwivumbure bukomeye.

Ni ryari ngomba kubonana na muganga wanjye?

Uzajya ugenzurwa na muganga wawe buri gihe . Bazakurikirana ibimenyetso byawe kandi bahindure uburyo uvurwa nibiba ngombwa. Niba ugaragaje ibimenyetso bishya, cyangwa niba ibimenyetso byawe birushijeho kwiyongera, bimenyeshe muganga wawe ako kanya.

Ni ryari nkwiye kujya mu cyumba cy’ubutabazi bw’ibanze?

Niba ufite ubwivumbure bukomeye cyane budashobora gukemurwa n'imiti, jya mu cyumba cy'ubutabazi bwihuse. Ni ukuvuga, niba ugize ibimenyetso nko kugorwa no guhumeka, umuhogo ufunganye, isereri ikomeye, cyangwa guta ubwenge.

Ni ibihe bibazo ngomba kubaza muganga wanjye?

Niba ufite Mastocytosis, ni byiza kubaza muganga wawe ibibazo nk'ibi:

• Ni ubuhe bwoko bwa Mastocytosis mfite?
• Ni ubuhe buryo bwo kuvura buhari ku bwoko bw'indwara mfite?
• Ese uburyo bwo kuvurwa buzakuraho burundu ibimenyetso byanjye?
• Ni ibihe bimenyetso by'inyongera bishobora kugaragaza ko indwara yanjye irushaho kuba mbi?
• Ese nzagomba kuvurwa ubuziraherezo?
• Niba mfite imiterere ikomeye kurushaho, ni iki giteganyijwe?
• Ese hari igeragezwa ry'ubuvuzi nshobora kwitabira?

Amaherezo, icyo ugomba kwibuka (Ubutumwa bwo kujyana mu rugo)

Mastocytosis ni indwara idakunze kugaragara itera gukura ku buryo budasanzwe kw'uturemangingo twa mast mu mubiri. Ishobora kugira ingaruka ku ruhu no ku ngingo z'imbere. Abantu benshi bashobora kwihanganira ibimenyetso byabo bamenya kandi bakirinda ibintu bibatera no gufata imiti. Ni ngombwa kandi kugumana inshinge za epinephrine hafi kugira ngo zivure ingaruka zikomeye z'ubwivumbure.

Nubwo iyi ari indwara idashobora gukira burundu, hamwe n'inama n'ubuvuzi bikwiye, ushobora kugerageza kugenzura ibimenyetso no kubaho ubuzima busanzwe. Niba ufite ibindi bibazo kuri ibi, ntutindiganye kuvugana na muganga wawe. Bazagufasha.

Mastocytosis, uturemangingo twa mast, histamine, allergie , indwara z'uruhu, ubudahangarwa bw'umubiri, anaphylaxis