Ese amaraso yawe afite ibyago byo kuvura? (Ihindagurika rya Prothrombin Gene) Reka tubyigeho mu buryo bworoshye

Ese wigeze wumva umuntu abyimbye ukuguru kandi ababara, akabwirwa na muganga ko afite amaraso mu kuguru kwe? Cyangwa umuntu ukiri muto kandi ufite ubuzima bwiza ahura n'ingorane zo guhumeka no kubabara mu gituza agahita ajyanwa mu bitaro? Iyo twumvise ibintu nk'ibi, dushobora kwibaza ibiri kuba. Akenshi, tubona ibintu nko gusaza no kubyibuha cyane nk'impamvu yabyo. Ariko, rimwe na rimwe impamvu ishobora kuba ikintu nk'ibara ry'amaso yacu, imiterere y'umusatsi wacu, cyangwa gene dukomoka ku babyeyi bacu. Uyu munsi tugiye kuvuga ku ndwara nk'iyi y'uturemangingo yongera ibyago byo kubyimba kw'amaraso. Ibi byitwa Prothrombin Gene Mutation .

Mu magambo make, iyi Prothrombin Gene Mutation ni iki?

Ibi bishobora kumvikana nk'izina rya siyansi, ariko inkuru ni yoroshye cyane. Reka tubanze turebe uburyo amaraso avura mu mubiri wacu. Iyo ugize imvune nto, amaraso make arasohoka hanyuma agahagarara nyuma y'igihe runaka, sibyo? Ibyo biterwa nuko sisitemu yo kuvura mu mubiri wacu iba ikora. Ubwoko bwinshi bwa poroteyine bufasha muri ibi. Izi poroteyine twita Ibintu Bituma amaraso avura. Prothrombin ni imwe muri izo poroteyine. Irindi zina ryabyo ni Factor II . Ubusanzwe, umubiri wacu ukora gusa ingano ya Prothrombin ukeneye. Ariko, mu mubiri w'umuntu ufite imiterere y'uturemangingo yitwa Prothrombin Gene Mutation, iyi poroteyine yitwa Prothrombin ikorwa mu rugero runini cyane kuruta uko bisabwa . Tekereza, byagenda bite umuntu aramutse yongeyeho ibiyiko bitanu cyangwa bitandatu by'isukari mu gikombe cy'icyayi aho gushyira ibiyiko bibiri by'isukari? Nk'uko icyayi kiryoha cyane, iyo urugero rwa prothrombin rwiyongereye, amaraso yacu arushaho "gufatana," cyangwa akagira ibyago byo kuvura. Ibi byongera ibyago byo kuvura amaraso mu mitsi, nubwo nta gikomere. Ibi bice by'amaraso biba mu mitsi yo mu birenge. Iyi ndwara twita Deep Vein Thrombosis (DVT) . Hari igihe igice cy'iyi ngingo y'amaraso gishobora gucika no kuziba imitsi yo mu bihaha. Iyi ni indwara iteje akaga cyane, yitwa Pulmonary Embolism (PE) .

Ni gute twabona iyi gene? Homozygous na heterozygous ni iki?

Ibi biroroshye cyane kubyumva. Dufata gene iyo ari yo yose nk'ikopi imwe iva kuri mama wacu n'ikopi imwe iva kuri data wacu. Tekereza kuri iyi gene ikora Prothrombin. 1. Heterozygous: Iyi gene ifite inenge uyikura kuri mama wawe cyangwa so, ni ukuvuga ku mubyeyi wawe umwe gusa. Undi muntu ahabwa gene nzima kandi isanzwe. Abantu benshi muri Sri Lanka no ku isi yose bafite iyi ndwara. Muri iki gihe, ibyago byo kuvura amaraso ni byinshi gato ugereranyije n'umuntu usanzwe. Mu buryo bugaragara, abantu babiri cyangwa batatu mu 1.000 bafite iyi ndwara bafite ibyago byo kurwara amaraso. 2.Homozygous: Ibi ni gake cyane. Ikibaho hano ni uko ubona gene ifite inenge kuri nyoko na so. Ibi bivuze ko ubona kopi zombi za gene ifite inenge ku babyeyi bombi . Muri iki gihe, ibyago byo kuvura amaraso biba byikubye inshuro nyinshi ugereranyije n'abafite `Heterozygous`.

Ese abana banjye bazaragwa ibi kuri njye?

Iki ni ikibazo ababyeyi benshi bafite.

• Niba ufite ikibazo cya homozygous (bivuze ko kopi zombi za gene zifite inenge), nta kabuza uzaha buri mwana wawe gene imwe ifite inenge.
• Niba ufite heterozygous (bivuze ko ufite gene imwe gusa ifite inenge), hari amahirwe 50% ko umwe mu bana bawe azaragwa iyo gene. Ni nko kuzunguza igiceri; ushobora kuyibona cyangwa ntuyibone.

Ni ibihe bimenyetso by'iyi ndwara?

Dore ikintu cy'ingenzi cyane. Nta bimenyetso byihariye ku ihinduka ry'uturemangingo ryitwa Prothrombin Gene Mutation. Ni ukuvuga ko nubwo waba ufite iyi gene mu mubiri wawe, nta tandukaniro cyangwa ingorane uzumva. Abantu benshi ntibazi ko bafite iyi gene, kandi babaho ubuzima bwabo bwose nta maraso afite. None se ikibazo kiri he? Ikibazo kiza gusa iyo amaraso agize amaraso bitewe n'iyi gene. Hanyuma tubona ibimenyetso bijyanye n'iyo mfu y'amaraso.

Ese hari ibindi bintu uretse utunyangingo tw’umubiri byongera ibyago byo kuvura amaraso?

Yego rwose. Twavuze ko atari buri wese ufite iyi gene uzarwara amaraso. Ariko, iyo hari kimwe cyangwa byinshi muri ibi bikurikira, ibyago bishobora kwiyongera. Ni nko gusuka lisansi ku muriro.

• Kunywa itabi: Kunywa itabi byangiza imiyoboro y'amaraso kandi byongera ibyago byo kubyimba kw'amaraso .
• Kubagwa: Nyuma yo kubagwa bikomeye, ushobora kumara iminsi myinshi uryamye mu buriri, ibyo bikaba byagutera kugabanuka kw'amaraso no kubyimba kw'ibibyimba.
• Umubyibuho ukabije : Uko ibiro by'umubiri byiyongera, ibi byago biriyongera uko umuvuduko mwinshi ushyirwa ku mitsi.
• Gutwita: Mu gihe cyo gutwita, ibyago byo kubyimba kw'amaraso byiyongera bitewe n'impinduka mu misemburo mu mubiri ndetse n'umuvuduko ku mitsi uterwa n'umwana uri gukura.
• Gufata ibinini byo kuboneza urubyaro cyangwa imiti igabanya imisemburo: Ingaruka zishobora kwiyongera bitewe n'imisemburo ya estrogen iri muri bimwe mu binini byo kuboneza urubyaro n'imiti igabanya imisemburo.
• Gusaza: Ibyago byo kuvura amaraso byiyongera uko umuntu akura.
• Kuguma mu mwanya umwe igihe kirekire cyane:
• Kuryama mu bitaro iminsi myinshi.
• Kwambara imashini iboshye iyo uvunitse ukuguru.
• Kugenda mu ndege, muri bisi, cyangwa mu modoka amasaha menshi icyarimwe.

Namenya nte ko mfite iyi ndwara?

Ibi ntibishobora kumenyekana hakoreshejwe isuzuma ry’amaraso risanzwe (nk’umubare wuzuye w’amaraso). Ikizamini cyihariye cya genetiki kirakenewe kuri ibi. Ibi bikorwa hakoreshejwe ikizamini cy’amaraso. Ariko, muganga ntabwo abwira buri wese gukora iki kizamini. Ubusanzwe, muganga abikeka ibi maze agategeka ko hakorwa ikizamini mu bihe bikurikira:

• Niba warigeze kugira amaraso menshi mbere.
• Niba urwaye indwara yo kubyimba kw'amaraso ukiri muto, ufite ubuzima bwiza, kandi nta zindi ndwara ufite.
• Niba ufite umuryango wa hafi mu muryango wawe (mama, papa, abavandimwe) afite ikibazo nk'iki cyo kuvura amaraso.

Ivurwa ite?

Aha tugomba kugaragaza ingingo ebyiri zisobanutse. 1. Kuvura ihindagurika ry’uturemangingo: Dukurikije siyansi y’ubuvuzi iriho ubu, nta buryo bwo kuvura cyangwa guhindura uturemangingo twacu. Ibi bivuze ko Prothrombin Gene Mutation izabana nawe ubuzima bwawe bwose. 2. Kuvura ihindagurika ry’amaraso: Ariko, dushobora kugenzura ibyago byo kuzura amaraso biterwa n’iyi gene no kuvura ihindagurika ry’amaraso ryabaye . Niba ufite DVT cyangwa PE, muganga wawe akunze gutangira kuguha ubwoko bw’imiti ibuza kuzura amaraso (ibyo dukunze kwita imiti igabanya amaraso). Mu buvuzi, iyi miti yitwa anticoagulants . Mu bihe bimwe na bimwe byihutirwa, imiti yitwa thrombolytics itangwa hakoreshejwe inshinge kugira ngo ishongeshe kandi ikurweho ihindagurika ry’amaraso. Ni gake cyane, catheter cyangwa kubagwa bishobora gukoreshwa kugira ngo bikureho ihindagurika ry’amaraso. Igihe cyo kuvurwa kiratandukanye bitewe n’umuntu ku wundi. Kuri bamwe, gufata imiti mu gihe cy’amezi atatu birahagije. Abandi bashobora gukenera gufata imiti igabanya amaraso mu buzima bwabo bwose. Muganga wawe azafata icyo cyemezo bitewe n’uburwayi bwawe n’ibintu bishobora gutera ibyago.

Ni gute iyi ndwara igira ingaruka ku gutwita?

Iki ni ikibazo cy'ingenzi ku bagore benshi.

• Niba ufite iyi Prothrombin Gene Mutation kandi ukaba warigeze kugira ikibazo cyo kuzura kw'amaraso mu gihe cyashize , muganga wawe ashobora kukugira inama yo gufata imiti yoroshya amaraso buri munsi (nk'iya heparin) mu gihe cyose utwite no mu byumweru bike nyuma yo kuvuka k'umwana wawe. Ubwo bwoko bw'inshinge ntabwo bugira ingaruka mbi ku mwana wawe.
• Ariko, nubwo waba ufite iyi gene, niba utigeze ugira amaraso mu buzima bwawe , ubusanzwe ntukenera kuvurwa mu gihe utwite.

Ni ryari ukwiye kujya kwa muganga?

Ibi ni ingenzi cyane. Kumenya ibimenyetso no gufata ingamba hakiri kare bishobora gukumira indwara zikomeye. Hanyuma, ntugatinye niba usanze ufite Prothrombin Gene Mutation. Wibuke ko abantu benshi bafite iyi gene bashobora kubaho ubuzima bwiza nta kibazo. Ikintu cy'ingenzi ni ukumenya ibi, kwirinda ibintu bishobora gutera ibyago (nk'itabi, umubyibuho ukabije), kubaho ubuzima bwiza, no gushaka inama z'abaganga vuba na bwangu niba ugaragaje ibimenyetso by'amaraso arwaye. Impinduka mu magini ya Prothrombin, impinduka mu buryo bwa kabiri, kuvura amaraso, kuvura imitsi yo mu mitsi miremire, kuvura imitsi yo mu bihaha, DVT, PE, Indwara z'ibimera, kugabanya amaraso, imiti igabanya amaraso.