Une mibvunzo here nezve bvunzo yeropa yeENA Panel (Extractable Nuclear Antigen Panel)? Ngatikurukurei zviri nyore!

Wakambonzwa here kuti masoja anofanirwa kutidzivirira kubva kuzvirwere, anoita chikanganiso otanga kurwisa nhengo dzedu dzine hutano? Izvi ndizvo zvatinodaidza kuti zvirwere zve autoimmune . Muzviitiko zvakadaro, kuongororwa kweropa kwakakosha kunonzi ENA panel kunogona kukubatsira kuti uone kuti dambudziko nderei uye kuti nei izvi zvichiitika. Saka nhasi, ngatitaurei nezve ENA Panel , iyo inomiririra Extractable Nuclear Antigen Panel , nenzira iri nyore yaunogona kunzwisisa, zvakanaka here?

Chii chaizvo chinonzi bvunzo yeENA?

Zvichitaurwa zviri nyore, panel yeENA inoongororwa ropa. Inoongorora kana masoja edu ekudzivirira muviri ari kuedza kurwisa nhengo dzine hutano dzemuviri wedu. Zvino ngatitsanangurei izvi zvishoma. Masoja edu ekudzivirira muviri akafanana neuto rinodzivirira nyika. Muuto iri, mune masoja akakosha, atinodaidza kuti ma antibodies . Basa rema antibodies aya nderekuziva nekurwisa utachiona , hwakadai semabhakitiriya nemavhairasi, anopinda mumuviri. Muvengi wese ane chiratidzo chakakosha pamuviri wake chinogona kuchiona, chatinodaidza kuti antigen mukurapa. Saka ma antibodies anoziva iyi antigen uye anorwisa muvengi. Isystem yakangwara kwazvo, handiti? Zvisinei, dzimwe nguva iyi system yakangwara inoita chikanganiso chidiki. Ndizvo zvinoitika mumamiriro ezvinhu anonzi zvirwere zve autoimmune . Chinoitika ipapo ndechekuti ma antibodies edu anotanga kuumbwa achirwisa mamwe mapuroteni zvidimbu (anonzi ma antigen anobviswa , zvichireva kuti "ma antigen anogona kuparadzaniswa nenucleus") anowanikwa munucleus (pakati pesero) yemasero ane hutano mumuviri wedu. Zvakafanana neuto redu richirwisa vagari vedu vane hutano. Panguva yakadaro, bvunzo yeENA inobatsira kuona kuti ndeapi maantigen edu ari kurwiswa nema antibodies aya. Izvi zvinogona kubatsira vanachiremba kufungidzira kuti rudzii rwechirwere che autoimmune chauinacho kana kusimbisa kuti hauna chirwere chakadaro.

Ndinofanira kuita bvunzo yeENA riini?

Havasi vese vanozofanira kuita bvunzo iyi yeENA. Pane mamiriro akati wandei apo chiremba anogona kuraira bvunzo iyi:

• Kana uine zviratidzo zvechirwere che autoimmune (semuenzaniso, kurwadziwa kwemajoini , kuneta kwakanyanya, matambudziko eganda) uye wakamboongororwa kuti une Antinuclear Antibody test (ANA) , bvunzo yeANA inoongorora zvirwere zve autoimmune .Kuongororwa kwekutanga kwekuona. Kana paine hutachiona, bvunzo yeENA ichabatsira kuferefeta zvichazoitika.
• Kana uine pamuviri uye wakamboonekwa uine lupus . Panguva ino, ma antibodies ako anogona kuyambuka placenta kuenda kumwana wako okonzera chirwere chinonzi neonatal lupus . Izvi zvinogona kukonzera matambudziko mumwana, akadai se heart block , saka chiremba wako anogona kukurudzira kuti uedze ENA test kuti utarise izvi.

Ndedzipi mhando dzezvirwere zvinoedzwa kuona ne ENA test?

Kune mhando dzakasiyana dzema antibodies dzinotsvakwa ne ENA test. Ma antibodies aya anonyanya kuenderana nechirwere chega chega che autoimmune. Zvirwere zvakajairika zvinotsvakwa ne test iyi ndeizvi:

• Lupus (Systemic Lupus Erythematosus /SLE)
• Chirwere cheSjögren
• Chirwere cheMixed connective tissue (MCTD)
• Scleroderma/systemic sclerosis
• Polymyositis
• Dermatomyositis

Chirwere chimwe nechimwe chine zviratidzo zvakasiyana, saka chiremba achaenzanisa zviratidzo zvako nemigumisiro yeongororo yeENA kuti asvike pamhedziso.

Bvunzo yeENA inoitwa sei? Inoshanda sei?

Zviri nyore kwazvo. Nyanzvi yekurabhoritari inotora ropa diki kubva mutsinga iri muruoko rwako. Zvadaro vanoshandisa ropa iri kuita bvunzo yeENA. Murabhoritari, vanoshandisa zviratidzo zvakakosha. Zviratidzo izvi zvinonamira kuma antibodies avari kutsvaga kana aripo. Zvadaro zviratidzo izvi " zvinopenya" kana kuchinja ruvara. Ndizvo zvinoita kuti ma chemicals aone kana ma antibodies aya aripo kana kuti kwete. Tekinoroji yepamusoro, handiti?

Ndeapi marudzi ema antibodies anotsvagwa ne ENA test?

Kazhinji, bvunzo yeENA inotsvaga ma antibodies anopindura ma antigen mana kusvika matanhatu anowanikwa mumasero edu. Rimwe nerimwe rema antibodies aya rinobatanidzwa nezvimwe zvirwere zve autoimmune nezvimwe zvirwere. Semuenzaniso, mamwe ma antibodies anobatanidzwa ne lupus.Zvimwe zvine chekuita nechirwere ichi, asi zvimwe zvine chekuita neSjögren 's syndrome . Ndosaka bvunzo iyi ichikosha pakuongororwa kwechirwere. Chiremba wako ndiye achasarudza kuti ndeapi masoja ekudzivirira chirwere aunofanira kutarisana nawo zvichienderana nezviratidzo zvako.

Ndinofanira kugadzirira bvunzo yeENA pachine nguva here?

Aya ndiwo mashoko akanakisa! Hamufanirwe kuita chero gadziriro dzakakosha musati maenda kunoongororwa ENA. Munogona kudya nekunwa zvakanaka uye kunwa mishonga yenyu. Zvakanaka kutaura nachiremba wenyu nezvazvo kuti muve nechokwadi.

Chii chaunotarisira paunenge uchinyora bvunzo yeENA?

Sezvambotaurwa, chiremba, nesi, kana nyanzvi yekurabhoritari vanoshandisa tsono diki kutora ropa shoma kubva mutsinga iri muruoko rwako. Unganzwa kurwadziwa kana kusagadzikana kana tsono ikaiswa yobviswa. Izvi zvinongotora masekondi mashoma chete. Kana uchitya tsono, zvinogona kubatsira kutarisa kure panguva iyi. Ropa richazotumirwa kurabhoritari kuti riongororwe.

Ndeipi njodzi dzekuongororwa kweENA?

Njodzi dzekuongororwa kweENA dzakaderera zvikuru , asi zvinhu zvidiki zvinogona kuitika kana ropa rikatorwa.

• Dzimwe nguva, kana zvichinetsa kuwana tsinga, ungafanira kubaya tsono kakawanda. Izvozvo zvinonetsa zvishoma.
• Unganzwa dzungu kana kupera simba paunenge uchitorwa ropa.
• Panogona kunge paine kukuvara kukuru kana kuunganidzwa kweropa pasi peganda pakaiswa tsono (izvi zvinonzi hematoma ).
• Kashoma, hutachiona hunogona kuitika panzvimbo yakarumwa.
• Vamwe vanhu vanogona kubuda ropa rakawanda kwenguva yakati mushure mekutorwa ropa.

Kana chimwe chinhu chakadai chikaitika, usavhunduke, ingozivisa vashandi vezvehutano.

Unowana sei mhedzisiro yekuongororwa kweENA? Zvinorevei?

Mhedzisiro yebvunzo inowanzova negative , positive , kana borderline (inonziwo equivocal) . Matanho akajairwa anogona kusiyana zvishoma zvichienderana nerabhoritari inoita bvunzo. Nokudaro, mushumo wako webvunzo unofanirwa kusanganisira mhedzisiro yako pamwe chete nereferensi yerabhoritari.

• Mhedzisiro yakanaka inoreva kuti antibody yakakodzera yakawanikwa muropa rako.
• Mhedzisiro isina kunaka zvinoreva kuti pakanga pasina ma antibodies anopesana ne antigen yakakodzera muropa rako, kana kuti pakanga paine mashoma kwazvo.

Kana bvunzo yeENA ikaonekwa kuti ine chirwere che lupus, zvinoreva here kuti ndine chirwere ichi?

Kwete, haugone kutaura kuti une chirwere chakati se lupus kubva pane zvakabuda muongororo imwe chete.

Izvi zvakakosha zvikuru. Kuongororwa kweENA hakurevi kuti une lupus . Semuenzaniso, vanhu vazhinji vane Sjögren's syndrome vanoonekwa vaine ma antibodies anonzi anti-SSA uye anti-SSB . Zvisinei, ma antibodies aya anogonawo kuva akanaka kune munhu ane lupus kana chimwe chirwere. Saka, chiremba wako achatora mhedzisiro ye ENA test, zviratidzo zvako, nezvimwe mhedzisiro yebvunzo (senge ANA test, CRP, ESR) pamwe chete kuti aongorore chirwere .

Ndinofanira kuona chiremba wangu zvakare rini?

Kana muine mibvunzo kana zvinokunetsai nezvemhedzisiro yenyu yekuongororwa, iva nechokwadi chekutaura nachiremba wenyu. Uyewo, kana muine kurwadziwa, kuzvimba, urwa panzvimbo yatorwa ropa, kana zviratidzo zvehutachiona hwakadai sefivha, endai kuchipatara (ETU) nekukasika.

Ndeupi musiyano uripo pakati pebvunzo yeANA nebvunzo yeENA?

Iri idambudzikowo kune vanhu vazhinji. Ngationei musiyano uripo pakati pezviviri izvi. Funga nezvebvunzo yeANA sebvunzo yekutanga, inowanzoitwa nemapurisa. "Pane chimwe chinhu chisina kumira zvakanaka pano, pane dambudziko re autoimmune here?" Kazhinji inoongororwa. Izvi zvinoyera kana mangani ma antibodies e antinuclear (antibodies anopesana ne cell nucleus) ari muropa rako uye kuti mangani ma antinuclear antibodies (antibodies anopesana ne cell nucleus) aripo. Bvunzo yeENA yakafanana nebvunzo yehunyanzvi inoitwa mushure meizvozvo. Kana ANA iri positive, vanoongorora zvakadzama vobvunza kuti, "Zvakanaka, kana paine chimwe chinhu chisina kumira zvakanaka, chii chaizvo? Ndeapi mapuroteni chaiwo (antigen) mumuviri wedu anogadzirwa ma antibodies aya?" Kureva kuti, bvunzo yeENA yakanyatsojeka kupfuura bvunzo yeANA. Vanhu vazhinji vane zvirwere zve autoimmune vane bvunzo yeANA yakanaka. Zvisinei, vanhu vane hutano vasina zvirwere zve autoimmune dzimwe nguva vanogona kuve ne positive ANA test (bvunzo yeENA inowanzova ne negative ye antibodies muvanhu vakadaro). Ndosaka vanachiremba vachiraira bvunzo yeENA kuti vawane rumwe ruzivo nezvechirwere che autoimmune mumunhu ane positive ANA test.

Pakupedzisira, zvinhu zvekurangarira

Panel yeENA (Extractable Nuclear Antigen panel) bvunzo inokosha inopa chiremba wako ruzivo rwakawanda nezvemasoja emuviri ari kukuvadza masero ako uye anogona kunge ari kukonzera zviratidzo zvako.

Hapana bvunzo imwe chete inogona kuona chirwere che autoimmune.

Chiremba wako achatora zvabuda muENA, zviratidzo zvako, nedzimwe bvunzo pamwe chete kuti awane kuongororwa kwakarurama. Saka, kana uine mibvunzo nezve zvabuda muongororo yako kana kuti zvingakanganisa sei sarudzo dzako dzehutano, usatya kubvunza chiremba wako. Ipapo iwewo unogona kuwana kunzwisisa kwakajeka. Kuongororwa kweENA, zvirwere zve autoimmune, ma antibodies, maantigen, lupus, kuongororwa kweropa, bvunzo yeANA