Ndinonzwisisa kutya, kuzvidya mwoyo, uye kusava nechokwadi kwaunonzwa kana chiremba wako achikuudza kana mumwe munhu waunoda kuti une kenza. Panguva imwe chete, kana chiremba wako achikuudza nezvemushonga unonzi "R-CHOP," pamwe une mibvunzo yakawanda inouya mupfungwa dzako, yakaita sekuti, "Chii ichi? Chinoita sei?" Usazvidya mwoyo. Nhasi, tichataura nezveR-CHOP chii, chii chainoita, uye maitiro ekugadzirisa nayo nenzira iri nyore yaunogona kunzwisisa.
Zvichitaurwa zviri nyore, chii chinonzi R-CHOP?
R-CHOP musanganiswa wemishonga mishanu inouraya masero egomarara . Imishonga inoshanda zvikuru yekurapa rudzi rwegomarara runonzi non-Hodgkin lymphoma . Bhii rega rega riri muzita rinoreva mushonga unoshandiswa mukurapa uku.
| Tsamba | Mushonga uye kushanda kwawo |
|---|---|
| R | Rituximab: Uyu mushonga unorapwa zvakananga. Kunyanya, mushonga uyu unobatanidzwa nepuroteni yakakosha pamusoro pemasero ekenza. Izvi zvinoita kuti masoja emuviri wedu akwanise kuona nekuparadza masero aya ekenza zviri nyore. |
| C | Cyclophosphamide: Uyu mushonga wechemotherapy. Mishonga yechemotherapy inoshanda nekuparadza masero anokamuka nekukurumidza, akadai semasero ekenza. |
| H | Doxorubicin hydrochloride (Hydroxydaunomycin): Uyu mushonga wechemotherapy zvakare. |
| O | Vincristine sulfate (Oncovin): Uyu mumwe mushonga wechemotherapy. |
| P | Prednisone: Uyu rudzi rwe steroid (corticosteroid). Inourayawo masero ekenza. Inobatsirawo kuderedza allergic reactions inogona kuitika nemimwe mishonga yeR-CHOP. |
Sezvamunoona, izvi zvinosanganisira mishonga yechemotherapy pamwe chete nemushonga unodzivirira immune system (Rituximab). Ndosaka vanachiremba dzimwe nguva vachidana kurapa uku kuti "immuno-chemotherapy."
Ndeapi marudzi ekenza anoshandiswa kurapa R-CHOP?
Kurapa uku kunonyanya kuitirwa mhando yegomarara rinonzi non-Hodgkin lymphoma . Kunoshandawo zvikuru kune mhando yakajairika yeB-cell lymphoma (DLBCL) . Pamusoro pezvo, R-CHOP inoshandiswawo kune mhando dzegomarara dzinotevera:
- Chirwere che follicular lymphoma chakafambira mberi
- Lymphoma yemasero eMantle
- Waldenstrom macroglobulinemia
Mune zvimwe zviitiko, chiremba wako angasarudza kupa R-CHOP pamwe chete nemishonga yemamwe marudzi ekenza.
Kurapa kunoshanda sei?
Kurapwa kweR-CHOP kunoitwa mu "ma "cycles". Kurapwa kwega kwega kunowanzoita mavhiki matatu (mazuva makumi maviri nerimwe). Kune zvikamu zviviri zve "cycle" iyi:
1. Mazuva ekurapwa: Mazuva aunopiwa mushonga.
2. Mazuva ekuzorora: Mazuva ekubvumira muviri wako kuti upore uye upore usati watanga chirongwa chinotevera.
Mazuva ekurapwa
Mushonga uyu unogona kupihwa kwemazuva mashanu. Prednisone ( steroid ) ipiritsi raunomedza. Mimwe mishonga mina inopihwa semvura ine saline mutsinga (intravenous infusion - IV). Izvi zvinoda kuti uende kuchipatara kana kukiriniki. Ikoko uchagara pachigaro uku muchina uchibaya mushonga zvishoma nezvishoma mutsinga iri mumuviri wako. Tsinga iyi inogona kunge iri muruoko rwako, ruoko, kana chipfuva. Kana kurapwa kwacho kuchiitwa kuburikidza nechipfuva, mudziyo mudiki unonzi `port-a-cath` (chemo port) unogona kuiswa pasi peganda.
Pazuva rekutanga rekurapwa, uchapihwa mushonga wekudzivirira kuda kurutsa. Uchapihwawo mushonga wekudzivirira allergies. RituximabZvakajairika kunzwa dzungu uye kudziya kana wapiwa mushonga. Ndosaka mushonga uyu uchipiwa nokungwarira pakutanga. Asi hapana chekunetseka nacho, sezvo uchapiwa mushonga unodiwa nguva isati yasvika kudzivirira allergies dzakakomba.
Mazuva ekuzorora
Mumazuva akajairika, unenge uine mazuva angangoita gumi nematanhatu ekuzorora mushure mekurapwa. Muviri unonzwa kuneta zvakanyanya sezvo mushonga weR-CHOP uchiparadza masero ekenza. Saka zvakajairika kunzwa kuneta zvakanyanya mumazuva aya. Munguva iyi, zvakanaka kukumbira rubatsiro kumhuri neshamwari nemabasa ezuva nezuva.
Mumazuva aya ekuzorora, kana uchinzwa wakasununguka, chiremba anokurudzira kuita maekisesaizi akareruka, sekufamba netsoka. Zvakakoshawo kunwa mvura yakawanda uye kudya chikafu chinovaka muviri .
Ndezvipi njodzi nemigumisiro yekurapwa uku?
Kufanana nechero mushonga, R-CHOP inogona kukonzera migumisiro yakaipa. Asi yeuka, chiremba wako achakupa mishonga yaunoda kudzivirira kana kugadzirisa migumisiro yakawanda iyi. Haasi munhu wese anowana migumisiro iyi yese. Inosiyana kubva kumunhu kusvika kumunhu. Ngatitarisei mimwe yemigumisiro yakaipa inowanzoonekwa.
| Migumisiro yakajairika | Zvekuziva uye zvekuita |
|---|---|
| Weti tsvuku/pingi | Doxorubicin ine ruvara rutsvuku. Weti yako inogona kunge yakatsvuka/pink kwemaawa anosvika makumi mana nemasere mushure mekurapwa. Izvi zvakajairika, musazvidya moyo. |
| Kusvotwa nekurutsa | Kunyangwe ukatora mushonga wekuda kuda kurutsa, ungangonzwa kuda kurutsa zvishoma. Pane kudya chikafu chikuru, chine mafuta, chine mhiripiri, idya chikafu chidiki, kakawanda. |
| Kudonha kwebvudzi | Izvi zvinowanzoitika kana munhu anwa chemotherapy. Kurasika kwebvudzi kunogona kutanga mukati memavhiki matatu mushure mekupiwa mushonga wekutanga. Zvisinei, bvudzi rinokura zvakare mushure mekunge kurapwa kwapera. |
| Kutonhora nefivha | Kurapwa nemakemikari kunogona kuderedza huwandu hwemasero machena eropa rako, izvo zvinowedzera njodzi yako yekutapukirwa. Uchapihwa jekiseni rinonzi G-CSF, iro rinobatsira kukura kwemasero machena eropa rako. Zvisinei, kana ukatanga fivha, taurira chiremba wako nekukasika. |
| Kuneta kwakanyanya (Kuneta) | Kurapwa kunogona kukonzera kudzikira kwemasero matsvuku eropa, zvichikonzera anemia. Kana uchinzwa kuneta, zorora. Kumbira rubatsiro pamabasa ezuva nezuva. |
| Kubuda ropa/mavanga zviri nyore | Dambudziko iri rinogona kuitika nekuda kwekudzikira kwemaplatelet. Chenjerera kuti usakuvara. Udza chiremba wako kana ukaona mavanga akawanda pamuviri wako. |
| Kunzwa kusanzwa/kunzwa kurira mumakumbo | Izvi zvinonzi peripheral neuropathy. Kana uchinzwa kukwenya kana kupisa mumaoko ako kana tsoka, udza chiremba wako. |
Yeuka kuti fivha inogona kuva chiratidzo chehutachiona hwakakomba. Kana fivha yako yadarika 38°C, fonera chiremba wako kana chipatara nekukasika.
Pamusoro peizvi, unogona zvakare kunzwa maronda mumuromo, mapundu paganda, musoro, kuvimbiwa kana manyoka, kurwadziwa pachipfuva, kushaya hope, uye kuchinja mafungiro. Taura nachiremba wako nezve chero chimwe cheizvi.
Ndinofanira kufonera chiremba rini?
Udza chiremba wako nekukasika kana ukaona zviratidzo zvitsva kana kana chimwe chezviratidzo zvako chikawedzera panguva yekurapwa, kunyanya kana ukatanga fivha.
Kana paine dambudziko rakadai sekuoma kwekufema kana kurwadziwa kwechipfuva kamwe kamwe, enda kuchipatara chiri pedyo neEmergency Department (ETU) nekukasika.
Ndingaite sei kuti nguva iyi yekurapwa ive nyore kwandiri?
Hondo iyi haisi yekurwa uri wega. Pane zvinhu zvishoma zvaunogona kuita kuti nguva ino ive nyore.
- Ziva: Taura nachiremba wako nezvekurapa kwako uye zvaunotarisira. Usatya kubvunza mibvunzo.
- Kumbira rubatsiro: Kumbira rubatsiro kubva kumhuri neshamwari nemabasa epamba, kugadzira chikafu, uye kuenda kuchipatara.
- Idya uye inwa zvakanaka: Idya chikafu chinovaka muviri. Inwa mvura yakawanda nemvura.
- Wana rubatsiro: Bvunza chiremba wako nezvemapoka ekutsigirana apo vamwe vari kurapwa zvakafanana newe vari kusangana nekenza. Isimba guru kuva nemumwe munhu wekugovana naye zvakaitika kwauri.
Mavhiki mashoma ekutanga ekurapwa kweR-CHOP anogona kuva nguva yakaoma. Mazuva ekurapwa kwemishonga anogona kuva marefu uye migumisiro yacho inogona kuoma kugadzirisa. Asi kune vanhu vazhinji, mhedzisiro yeR-CHOP inokosha kupfuura kushanda nesimba. Kusanganiswa kwemishonga iyi mitatu (yakanangwa, chemo, uye steroids) kunoshanda kuuraya masero ekenza zvinobudirira. Zvichienderana nekuongororwa kwawakaitwa, izvi zvinogona kutungamira mukureruka kwegomarara zvachose.
Mharidzo Yekuenda Nayo Kumba
- R-CHOP musanganiswa unoshanda zvikuru wemishonga mishanu inoshandiswa kurapa magomarara akadai senon-Hodgkin lymphoma.
- Kurapa kunoitwa mu "cycles." Munguva iyi, zvakajairika kusangana nemigumisiro yakadai sekuneta, kuda kurutsa, uye kurasikirwa nebvudzi.
- Migumisiro yakawanda inogona kugadziriswa. Gara uchitaura nechikwata chako chekurapa nezvazvo.
- Kana ukaita fivha panguva yekurapwa, funga kuti idambudziko uye tsvaga rubatsiro rwechiremba nekukasika.
- Hamufanirwe kufamba rwendo urwu muri mega. Tsvagai rutsigiro kubva kumhuri, shamwari, uye timu yenyu yezvekurapa. Makasimba. Munogona kuita izvi.
R-CHOP, kenza, Non-Hodgkin lymphoma, chemotherapy, kurapwa kwakanangana, kurapwa kenza, migumisiro yakaipa
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