Haunawo dambudziko rekumisa kubuda ropa kunyangwe paganda diki here? Ngatitaurei nezvechirwere chevon Willebrand!

Dzimwe nguva unombova neganda diki risingaregi kubuda ropa kwenguva yakareba here? Kana kuti unombobuda ropa mumhino kakawanda here? Pamwe mumwe munhu mumhuri mako ane matambudziko akafanana? Kana zvakadaro, ichi chinhu chingave chakakosha kwauri. Nhasi tichataura nezvechirwere chisingawanzoitiki asi chinowanzoitika chinonzi von Willebrand Disease .

Chii chinonzi chirwere cheVon Willebrand?

Zvichitaurwa zviri nyore, chirwere chevon Willebrand chirwere umo ropa redu risingagwambi zvakanaka, zvichireva kuti maitiro anobatsira kumisa kubuda ropa anodzikira. Izvi zvinowanzo gara nhaka , zvichireva kuti vabereki vanogona kutapurira chirwere ichi kuvana vavo. Asi musazvidya mwoyo, pane mushonga weizvi. Vanachiremba vanogona kukupa mishonga inobatsira nemaitiro aya ekugwamba kweropa.

Chii chinoitika kumunhu ane chirwere chevon Willebrand?

Munhu ane chirwere ichi anogona kubuda ropa zvakanyanya kupfuura zvakajairika. Chimbofungai, kunyangwe kucheka kudiki kana kubviswa kwezino kunogona kutora nguva yakareba kuti ropa rimire kubuda. Vamwe vanhu vanowanzobuda ropa mumhino. Kune vakadzi, vanogona kubuda ropa rakawanda panguva yekuenda kumwedzi, kana kuti vanogona kubuda ropa rakawanda mushure mekusununguka.

Muzviitiko zvakanyanya zvechirwere ichi, kubuda ropa kunogona kuitika dzimwe nguva pasina chikonzero chakajeka mumapfundo kana munyama dzakapfava. Izvi zvinogona kukonzera kuzvimba nekurwadziwa kwakanyanya. Kune vamwe, zvinogona kutokonzera anemia , inova kushomeka kweropa .

Dambudziko iri rakajairika zvakadii?

Ichi ndicho chirwere chekubuda ropa chakajairika pasi rose. Mimwe mishumo inoratidza kuti chinokanganisa vanhu vanosvika 1% vekuAmerica. Pasi rose, zvinofungidzirwa kuti vanhu vari pakati pe23 ne110 pavanhu vane mamiriyoni vanogona kuva nechirwere ichi. Zvisinei, nhamba idzi dzinogona kusiyana, sezvo vamwe vanhu vangave vaine matambudziko ekubuda ropa asi vasingaonekwe kuti vane chirwere chevon Willebrand . Vamwe vanhu vangave vaine matambudziko aya kwemakore, asi havaonekwe kusvika zvapera.

Ko chirwere chevon Willebrand nehemophilia zvakafanana here?

Ehe, kunyange zvazvo zvose zviri matambudziko ekugwamba kweropa, chirwere chevon Willebrand chirwere chinowanzova nezviratidzo zvishoma uye chisina kusimba zvakanyanya sehemophilia . Asi izvozvo hazvirevi kuti chinhu chekuregeredza.

Ndezvipi zviratidzo zvechirwere chevon Willebrand?

Vanhu vazhinji vane chirwere ichi vanogona kunge vasina zviratidzo zvachose , kana kuti zviratidzo zvishoma. Zvisinei, avo vane chirwere chakanyanya kuoma vanogona kuona zviratidzo zvakaita se:

• Kubuda ropa mumhino : Uku hakusi kubuda ropa kwakajairika chete. Kunogona kubuda ropa kwemaminitsi anopfuura gumi, kana kubuda ropa mumhino kanopfuura kashanu pagore.
• Kubuda ropa kubva paronda: Kubuda ropa kubva paronda diki kana rimwe ronda kweanopfuura maminetsi gumi.
• Mavanga: Vanhu vane chirwere ichi vanowana mavanga nyore nyore. Mavanga aya haasi eganda chete, asi anogona kuzvimba zvishoma uye kukwidzwa sebundu. Mavanga aya anogonawo kuva akakura kupfuura mari yerupi mashanu.
• Kushaikwa kwesimbiKushaya iron: Anemia chirwere apo muviri hauna masero matsvuku eropa akakwana. Kushaya iron anemia kunoitika kana muviri wedu usina iron yakakwana yekugadzira hemoglobin . Chinhu ichi, chinonzi hemoglobin, chinobatsira masero matsvuku eropa kutakura okisijeni. Saka, kana tikarasikirwa neropa rakawanda, tinogonawo kurasikirwa nesimbi uye kukura nechirwere ichi.
• Kubuda ropa mushure mekuvhiyiwa: Vanhu vane chirwere ichi vanogona kubuda ropa rakawanda, kunyangwe mushure mekuvhiyiwa kudiki, sekubviswa kwezino.
• Kuenda kumwedzi zvakanyanya: Kune vamwe vakadzi, kana kubuda ropa kwavo kwemwedzi kwakanyanya zvekuti vanofanirwa kuchinja pedi kana tampon yavo awa yega yega, kana kana kuenda kumwedzi kwavo kukagara kwemazuva anopfuura manomwe, zvinogona kunge zviri chiratidzo chechirwere ichi.
• Kubuda ropa rakawanda mushure mekusununguka kana kuti pamuviri pakabva.
• Ropa mutsvina: Ungave uine ropa mutsvina yako kana ropa mushure mekupedza tsvina, zvinogona kuva chiratidzo cheimwe chirwere. Saka , unofanira kuona chiremba .
• Ropa muweti (hematuria): Kana ukaona ropa paunenge uchiita weti, kunyanya kana ropa racho richiuya pamwe chete nepfungwa yekungoerekana wada weti, taura nachiremba nekukasika .

Chinhu chinonyanya kukosha ndechekuti kana uine chimwe chezviratidzo izvi kana kupfuura, usazviregeredza wobva waona chiremba kuti akupe mazano.

Chii chinokonzera chirwere cheVon Willebrand?

Ichi chirwere chemajini . Izvi zvinoreva kuti chirwere ichi chinokonzerwa nekuchinja (kuchinja) kwemajini edu. Nekuda kwekuchinja kwemajini aya, muviri wedu haugone kugadzira puroteni inonzi von Willebrand factor nemazvo. Zvinhu izvi mapuroteni anobatsira kuumbwa kweropa redu.

Chinhu ichi chinonzi von Willebrand chinowanikwa muplasma (chikamu cheropa redu chinoyerera), maplatelet (masero anobatsira kuumba ropa), uye madziro etsinga dzeropa . Kazhinji, kana tsinga yeropa yakuvara, maplatelet anonamira panzvimbo yakakuvara, zvichiita ganda reropa uye zvinomisa kubuda kweropa.Von Willebrand factor ndiyo inobatsira kuti maplatelet aya abatane zvakanaka. Saka, kana ukarasikirwa nechinhu ichi zvakakwana, kana kuti ukarasikirwa nacho zvachose, maplatelet haakwanise kunamira zvakanaka. Zvadaro zvinotora nguva yakareba kuti ropa riumbwe.

Vanhu vazhinji vanowana chirwere ichi nekugara nhaka yejini rakachinja kubva kune mumwe wevabereki vavo . Izvi zvinonzi autosomal dominant inheritance . Vamwe vanogona kugara nhaka yejini rakachinja kubva kuvabereki vese . Izvi zvinonzi autosomal recessive inheritance , uye ndiyo mhando yakanyanya yechirwere ichi. Munhu ane jini iri rakachinja ane mukana we50% wekupa mutation kuvana vake.

Uyewo, dzimwe nguva chirwere chevon Willebrand chinogona kuitika sedambudziko rezvimwe zvirwere, zvakaita sekenza , zvirwere zve autoimmune , chirwere chemwoyo, uye zvirwere zvetsinga dzeropa.

Vanachiremba vanoongorora sei chirwere cheVon Willebrand?

Kana waona chiremba, vanotanga vakubvunza nezvezviratidzo zvako. Vanogonawo kubvunza kana paine munhu mumhuri mako akambova nezviratidzo zvakafanana kana matambudziko ekubuda ropa. Zvadaro vanogona kuita mimwe miedzo, yakaita se:

• Kuverengwa kweropa kwakazara (CBC): Izvi zvinoyera huwandu hwemasero matsvuku eropa, mhando dzakasiyana dzemasero machena eropa, uye maplatelet muropa rako. Zvinoyerawo huwandu hwehemoglobin mumasero matsvuku eropa rako. Vanhu vazhinji vane chirwere chevon Willebrand vane CBC yakajairika. Zvisinei, vanhu vanobuda ropa rakawanda vanogona kunge vaine hemoglobin shoma uye masero matsvuku eropa mashoma.
• Kuongororwa kwekuunganidza maplatelet: Izvi zvinoongorora kuti maplatelet ako anonamatirana sei kuti abatsire kuumba macoats eropa.
• Kuedza kwenguva yeropa kunoitwa partial thromboplastin (APTT): Iyi bvunzo ye von Willebrand factor nezvimwe zvinhu zvinogwamba ropa zvinobatsira kugwamba kweropa. Kana huwandu hwezvinhu izvi hwakaderera pane zvakajairwa, zvinotora nguva yakareba kuti ropa rigwambe.
• Kuongororwa kwenguva yeprothrombin (PT): Izvi zvinoyerawo zvimwe zvinhu zvinoita kuti ropa rigwambe.
• Kuongororwa kweFibrinogen:Fibrinogen imwe puroteni inobatsira kuumba ropa.
• Kuongororwa kweVon Willebrand factor antigen: Izvi zvinoyera huwandu hweprotein yevon Willebrand factor muropa rako.
• Kuongororwa kweRistocetin cofactor: Izvi zvinoongorora mashandiro evon Willebrand factor.
• Bvunzo yeVon Willebrand factor multimers: Iyi inotarisa chimiro chechinhu.

Chiremba wako angangoda kuita bvunzo dzeropa dzinoverengeka kuti asimbise chirwere ichi, nekuti zvinhu zvakaita semazinga emahormone zvinogona kuchinja huwandu hwevon Willebrand factor muropa rako.

Kune mhando dzakasiyana dzechirwere chevon Willebrand. Vanachiremba vachaita bvunzo dzakawanda kuti vaone kuti nderudzii rwaunarwo. Mhando idzi ndeidzi:

• Rudzi 1: Urwu ndirwo rudzi rwakajairika. Pakati pe60% ne80% yevarwere vane rudzi urwu. Vanhu ava vane huwandu hwakaderera hwevon Willebrand factor muropa ravo. Vanogona kunge vasina zviratidzo. Kana zvikaitika, zvinenge zvisina kusimba.
• Rudzi rwechipiri: Murudzi urwu, von Willebrand factor haishande nemazvo. Vanhu ava vanogona kubuda ropa zvishoma kusvika pakati nepakati. Pakati pe15% ne30% yevarwere vane rudzi urwu.
• Rudzi rwechitatu: Urwu ndirwo rudzi rwakanyanya kuoma. Haruwanzoitiki. Runobata pakati pe5% ne10% yevarwere. Vanhu ava vane huwandu hwakaderera hwevon Willebrand factor muropa ravo, kana kuti hapana zvachose. Izvi zvinogona kukonzera matambudziko makuru ekubuda ropa.

Ndeipi mishonga yekurapa chirwere chevon Willebrand?

Vanachiremba vanorapa chirwere ichi nemhando dzakasiyana dzemishonga:

• (Desmopressin): Iyi ihormone. Inowedzera huwandu hwevon Willebrand factor muropa. Iyi ndiyo nzira inonyanya kushandiswa pakurapa chirwere ichi.
• Kuisirwa kweVon Willebrand factor: Vamwe vanhu vanopihwa factor iyi kuburikidza netsinga kuti vamise kubuda ropa. Kurapa uku kunogona kuitwa vasati vavhiyiwa. Vamwe vanhu vane chirwere chakakomba vangangoda kurapwa uku nguva nenguva kuti huwandu hwefactor muropa ravo hurambe hwakagadzikana.
• (Mishonga yekudzivirira fibrinolytics):Mishonga iyi inoshanda nekudzivirira kuumbwa kweropa rakagwamba. Chiremba wako anogona kukupa mishonga iyi kana uri kuvhiyiwa mazino kana kuti uri kubuda ropa rakawanda panguva yekuenda kumwedzi.
• Mapiritsi ekudzivirira pamuviri: Aya anobatsira avo vanobuda ropa rakawanda panguva yekuenda kumwedzi. Homoni yeestrogen iri mumapiritsi aya inowedzera huwandu hwevon Willebrand factor muropa.

Ndingaderedza here njodzi yekubatwa nechirwere ichi?

Izvi zvinowanzo gara nhaka . Kana vabereki vako vaine chirwere ichi, unogona kuchigara nhaka kubva kune mumwe wavo kana vese. Saka hapana chatingaita kuti chisatange.

Kana ndine chirwere ichi, chii chandinofanira kutarisira?

Vanachiremba vanogona kurapa chirwere chevon Willebrand, asi havakwanise kuchirapa zvachose . Vanhu vazhinji vane rudzi rwekutanga kana rwechipiri. Vanongoda kurapwa chete kana vakakuvara kana vachida kuvhiyiwa. Vanhu vane rudzi rwechitatu vangangoda kurapwa nguva dzose kuti vadzore kubuda ropa.

Ndine chirwere chevon Willebrand. Ndinofanira kuzvitarisira sei ?

Sezvo vanhu vazhinji vaine zviratidzo zvishoma kusvika pakati nepakati, kurarama nechirwere ichi zvinoreva kufunga nezvezvinhu zvishoma:

• Dzivisa mitambo inogona kukonzera kukuvara: Zvakanaka kusaita mitambo ine simba guru, semuenzaniso, nhabvu, rugby, uye hockey.
• Udza vanachiremba vako vese, kusanganisira chiremba wemazino, kuti une dambudziko iri: vanogona kuronga nzira yekudzora kubuda ropa mushure mekuvhiyiwa.
• Usashandise aspirin kana mishonga ine aspirin.
• Usashandise mishonga isingashandisi masteroidal anti-inflammatory (NSAIDs) , yakaita seibuprofen, kunze kwekunge wanyorerwa nachiremba anoziva kuti une chirwere chevon Willebrand.
• Dzivisa kutora mishonga inovaka muviri ine vhitamini E, mafuta ehove, uye turmeric.
• Funga nezvechiratidzo chekuzivisa nezvekurapa: Kupfeka bracelet yakaita seiyi kana kutakura kadhi rekuzivisa kunogona kukubatsira kuwana rubatsiro rwakakodzera rwechiremba kana paine emergency.

Ndinofanira kuenda kuchipatara nekukurumidza riini?

Enda kuchipatara nekukasika chero nguva yaunenge uchibuda ropa zvisingadzoreki . Kunyangwe kana kuri kukuvara kudiki, kana ropa rikasamira, iva nechokwadi chekutsvaga rubatsiro rwechiremba.

Mibvunzo ipi yandinofanira kubvunza chiremba?

Kana uine chirwere chevon Willebrand, ungave nemibvunzo yekuti chirwere ichi chichakanganisa sei hupenyu hwako. Heano mimwe mibvunzo yaunogona kubvunza chiremba wako:

• Sei ndakawana chirwere ichi?
• Vana vangu vanogona kugara nhaka yechirwere ichi here?
• Izvi zvichatowedzera kuipa here?
• Ndezvipi zvinorapwa izvi?
• Ndezvipi migumisiro yekurapwa?
• Handizokwanisi here kuita zvimwe zvinhu, zvakaita sekufamba kana kutamba mitambo, nekuda kwechirwere ichi?

Muchidimbu, zvinhu zvatinofanira kurangarira ndeizvi:

Chirwere cheVon Willebrand chirwere chinowanzoitika mumajini, chinobata ropa. Vanhu vazhinji vane zviratidzo zvishoma kusvika pakati nepakati. Vanogona kubuda ropa mumhino kakawanda, kana kuti kunyange kucheka kudiki kunogona kutora nguva yakareba kuti ropa rimire kubuda. Vamwe vane zviratidzo zvakakomba. Semuenzaniso, vanogona kunge vaine ropa mumajoini avo uye kurwadziwa kwemajoini.

Vamwe vanhu vangasaziva kuti vane chirwere ichi kwemakore. Kana uine chirwere ichi, zvingava zororo kuziva kuti sei uine matambudziko ekubuda ropa. Ungave uchinetsekawo kuti vana vako vachavawo nechirwere ichi. Kunyange zvazvo vanachiremba vasingakwanise kurapa chirwere ichi, vanogona kuchirapa . Vanogonawo kupindura mibvunzo yako yekuti vana vako vachachigara nhaka here. Vanogonawo kukupa ruzivo rwaunoda kuti urarame nechirwere chevon Willebrand kuitira kuti chisakutadzise kurarama hupenyu hune simba uye hwakajairika. Saka, usazvidya mwoyo, kana ukachinzwisisa uye uchichibata nemazvo, unogona kurarama zvakanaka nacho.