Unoziva nezvechirwere cheWhipple here? Ngatitaurei nezvechirwere ichi chisingawanzoitiki nemashoko akareruka!

Dzimwe nguva unonzwa sekuti muviri wako hauna simba, une matambudziko emudumbu, une marwadzo emajoini, asi haugone kuwana chikonzero chacho here? Pamwe ichi chirwere chisina kumbonzwikwa nevanhu vazhinji, asi zvakakosha kuziva. Nhasi tichataura nezvechimwe chirwere chisingawanzoitiki, asi kana chikarapwa nemazvo, chinorapika. Ichi chirwere cheWhipple.

Chii chinonzi chirwere cheWhipple?

Zvichitaurwa zviri nyore, chirwere cheWhipple chirwere chebhakitiriya chisingawanzoitika chinoitika muura hwako hudiki . Izvi zvinokonzerwa nekuti chikafu chaunodya hachigayiwi zvakanaka uye zvinovaka muviri zvaunoda hazvisi kupinda mumuviri wako (izvi zvinonzi "malabsorption"). Funga nezvazvo, tinodya chikafu kuti tiwane simba nekudya kunovaka muviri kwemiviri yedu. Saka kana chisina kunyudzwa zvakanaka, matambudziko mazhinji anogona kuitika. Chirwere ichi chinoitika kana bhakitiriya inonzi "Tropheryma whipplei" ikapinda mumuviri. Mabhakitiriya aya anowanzo kuwanikwa muvhu, kureva muvhu. Asi mashoko akanaka ndeekuti ne "antibiotics" chaiyo, bhakitiriya iyi inogona kubviswa mumuviri, kuderedza zviratidzo, uye kurapwa zvachose .

Chirwere cheWhipple chakajairika zvakadii?

Heino chinhu chakakosha. Kunyangwe mabhakitiriya anokonzera chirwere ichi ((Tropheryma whipplei)) akawanda munharaunda, kunyanya muvhu, chirwere chaWhipple chirwere chisingawanzoitiki . Sekureva kwevaongorori vezvekurapa, kunyangwe munyika yakaita seAmerica, zvinofungidzirwa kuti vanhu vanosvika vapfumbamwe pamamiriyoni vanochiwana. Izvi zvinoreva kuti havasi vese vanobatwa nechirwere ichi. Chikonzero chaicho hachisati chazivikanwa.

Ndezvipi zviratidzo zvechirwere chaWhipple?

Zviratidzo zvechirwere cheWhipple hazvionekwi kamwe kamwe. Zvinokura zvishoma nezvishoma mumatanho akati wandei .

Zviratidzo zvechikamu chekutanga (Prodromal Phase)

Zvinotanga nekurwadziwa kwakanyanya kwemajoini . Kurwadziwa uku kunogona kuuya kwoenda. Kunonyanya kukanganisa majoini ako makuru - zvitsitsinho zvako, magokora, chiuno, mabvi, nemapendekete . Vanachiremba dzimwe nguva vanodana danho iri rekutanga kuti "prodromal phase." Izvi zvinogona kugara kwemakore manomwe kana masere , uye zvimwe zviratidzo zvinotanga kuoneka. Fungidzira kuti zvakaoma sei kuva nekurwadziwa kwemajoini kwemakore usingawani chikonzero.

Zviratidzo zvepashure

Mushure menguva yakati, zviratidzo zvinotevera zvinogonawo kuoneka:

• Kurwadziwa kwemudumbu: Hakusi kurwadziwa kwemudumbu chete, asi kunogona kuva kurwadziwa kunowedzera mushure mekudya kana kuramba kuripo.
• Manyoka (tsvina ine mvura): Tsvina ine mvura inoitika kakawanda pazuva. Izvi zvinogona kukonzera kupera mvura mumuviri uye kurasikirwa nezvinovaka muviri.
• Kuzvimba (Edema): Unogona kuona kuzvimba, kunyanya mumakumbo nemuzviziso. Kana uchinzwa sekuti une dimple paunodzvanya nemunwe wako, zvinogona kunge zviri kuzvimba.
• Kuneta kunowanzoitika:Kunyangwe ukavata zvakadii, muviri wako unonzwa usina hupenyu uye haunzwi kuda kuita chero chinhu.
• Fivha: Kunzwa kupisa pasina chikonzero.
• Kuchinja ruvara rweganda: Dzimwe nzvimbo, kunyanya idzo dzinopiswa nezuva, dzinogona kusviba kupfuura zvakajairika.
• Ma lymph nodes akazvimba: Mapundu madiki munzvimbo dzakadai semutsipa, muhapwa, uye muzvidya.
• Kudzikira kwehuremu kusingatsananguriki: Kudzikira kwehuremu pasina kudya kana kurovedza muviri.

Matambudziko eSistimu yeNervous yeCentral

Pakati pe20% ne40% yevanhu vane chirwere cheWhipple vanotambura nematambudziko etsinga dzemutsinga . Ichi chirwere chakakomba. Zviratidzo zvinogona kusanganisira:

• Matambudziko ekuenzanisa: Unonzwa kusagadzikana paunenge uchifamba uye haugone kumira wakatwasuka.
• Kuvhiringidzika: Kurasikirwa neruzivo rwekuti uri kupi, nguva, uye kunyange vanhu vaunoziva.
• Kuoma kwekumedza: Kunzwa sekunge uri kudzipwa paunenge uchimedza chikafu kana chinwiwa.
• Kurasikirwa nendangariro: Kukanganwa kunyange zviitiko zvechangobva kuitika.
• Kuchinja kwehunhu: Kunzwa sekuti hausisiri munhu wawaimbova, kukurumidza kutsamwa, uye kushatirwa.
• Kubatwa nepfari: Kurasikirwa nepfungwa kamwe kamwe uye kubatwa nepfari.
• Zvipingamupinyi zvekutaura: Kusanzwisisana kwemashoko, kusakwanisa kutaura zvakajeka.

Chii chinokonzera chirwere chaWhipple?

Sekuziva kunoita vanachiremba, chirwere ichi chinokonzerwa nerudzi rwebhakitiriya (Tropheryma whipplei) rinowanikwa muvhu . Munhu wese anosangana nebhakitiriya iri ari panjodzi yekutapukirwa. Zvisinei, sezvatakambotaura, chirwere chaWhipple hachiwanzoitiki. Saka, hazvisati zvanyatsojeka kuti sei vamwe vanhu chete vachichiwana .

Zvisinei, tsvakiridzo yakawana kuti zvinhu zvinotevera zvinogona kuwedzera njodzi yekubatwa nechirwere ichi :

• Zera: Chirwere cheWhipple chakaratidzwa kuti chinowanzobata vanhu vari pakati pemakore 65-84 , asi chinogonawo kuitika kuvanhu vari pasi pemakore iwayo.
• Kusangana nevhu kana kuchengeta mhuka: Ongororo inoratidza kuti vanhu vanoshanda nevhu kana kuchengeta mhuka vari panjodzi huru yekubatwa nechirwere ichi. Zvikuru sei, vanhu vanorima, vanorima mubindu, kana vanoshanda nemhuka vanogona kunge vari panjodzi huru. Unogona kutosangana nehutachiona uhwu kana ukadyara chimwe chinhu chidiki mubindu rako repamba.
• Kuchinja kwemajini:Pane hukama huripo pakati pechirwere cheWhipple nejini rinogadzira puroteni (IFR4). Puroteni iyi inobatsira masero emuviri wedu ekudzivirira muviri, akadai se(masero eB) uye(masero eT), kukura. Zvakaonekwawo kuti zvakabatana nekuchinja kwejini (HLA-B27). Izvi zvakadzama, asi muchidimbu, shanduko dzakati wandei mumajini edu dzinogona kutikonzera izvi.
• Kusasimba kwemasoja emuviri: Kana uine chirwere chinokanganisa masoja emuviri wako (senge HIV), kana ukatora mishonga inodzvinyirira masoja emuviri (aya anopihwa kune zvimwe zvirwere, dzimwe nguva kune zvinhu zvakaita searthritis, kana mushure mekuisirwa nhengo), uri panjodzi huru yekubata chirwere ichi.

Ndezvipi zvinetso zvinogona kuitika nekuda kwechirwere chaWhipple?

Sezvatakambotaura, chirwere cheWhipple chinokonzerwa nekusakwanisa kwemuviri kupinza mafuta, makabhohaidhiretsi, mavhitamini, nezvimwe zvinovaka muviri kubva muchikafu chinopfuura nemuura hwako hudiki. Chirwere ichi chinoramba chichikura nekufamba kwenguva . Izvi zvinoreva kuti kana chikasarapwa, matambudziko matsva ehutano anogona kukura.

Zvinetso zvakadaro zvinogona kuitika:

• Anemia (kuderera kwehuwandu hwemasero matsvuku eropa): Izvi zvinogona kukonzera kuneta nguva dzose, kushaya simba, uye kucheneruka.
• Dementia (kurasikirwa nendangariro nekushanda kwepfungwa): Izvi zvinogona kuitika kana sisitimu yetsinga ikakanganiswa.
• Kugunun'una kwemoyo: Izvi zvinogona kunzwika kana chiremba akakuongorora ne stethoscope.
• Oculomasticatory myorhythmia: Ichi chiratidzo chaicho, apo maziso neshaya zvinoita sezviri kufamba pamwe chete .
• Kubuda kweropa muropa: Izvi zvinogona kukonzera kufema kuomera.
• Uveitis: Zviratidzo zvinogona kusanganisira kutsvuka, kurwadziwa, uye kuona zvisipo.

Chinonyanya kukosha ndechekuti kana chirwere cheWhipple chikakanganisa tsinga dzemuviri wako, chinogona kuuraya. Saka zvakakosha kuti uone chiremba nekukasika kana uine zviratidzo.

Vanachiremba vanoongorora sei chirwere chaWhipple?

Paunoenda kunoona chiremba, iye achatanga akuongorora muviri wako . Zvadaro, vachakubvunza nezvenhoroondo yako yehutano , kusanganisira matambudziko ehutano aripo iye zvino kana ekare. Vanogonawo kubvunza nezvemishonga yaunotora uye kana paine mumwe munhu mumhuri mako akambova nedambudziko iri. Pamusoro pezvo, vanogona kuita bvunzo dzinotevera:

• Kuverengwa Kweropa Kwakakwana (CBC) : Izvi zvinoongorora mamiriro emasero eropa emuviri, kana paine anemia, uye kana paine zviratidzo zvehutachiona.
• Endoscopy yepamusoro yeura hudiki: Muizvi, chubhu ine kamera diki inopinzwa nemuromo yotariswa mukati meura diki. Nenzira iyi, chero shanduko dziripo, zviratidzo zvehutachiona, zvinogona kuongororwa. Ucharadzikwa usati waita izvi, saka hauzonzwi kurwadziwa.
• Kuongororwa kwePolymerase Chain Reaction (PCR) : Uku kuongorora kwakakosha kunogona kubatsira kuona kana mabhakitiriya (T. whipplei) aripo. Kunogona kuitwa pachidimbu chenyama chakatorwa kubva mu biopsy kana pamwe pane chimwe chinwiwa chemuviri.
• Kuongororwa kweura hudiki : Panguva ye endoscopy, kanyama kadiki kanotorwa kubva muura hudiki koongororwa nemaikorosikopu. Izvi zvinowanzoshandiswa kusimbisa chirwere chaWhipple. Zvinogona kutsvaga shanduko dzakati wandei muura hunokonzerwa nebhakitiriya.

Chirwere cheWhipple chinorapwa sei?

Zvinotora nguva kuti mabhakitiriya anokonzera chirwere cheWhipple abviswe mumuviri zvachose. Saka, kurapwa kwenguva refu. Asi kana ukashivirira, unogona kuwana mhedzisiro yakanaka.

Izvi ndizvo zvinhu zvikuru zvinoitwa sekurapa:

• Mishonga inorwisa mabhakitiriya : Kurapa kunowanzo tanga nemishonga inorwisa mabhakitiriya inopinzwa mutsinga kwemavhiki maviri kusvika mana . Izvi zvinowanzoitwa muchipatara. Mushure meizvozvo, uchafanira kutora mishonga inorwisa mabhakitiriya inonwiwa kwemwedzi gumi nemiviri inotevera . Dzimwe nguva, ungangoda kuitora kwenguva yakareba, kusvika kumakore maviri. Zvakakosha kutora mushonga wacho sezvakarairwa nachiremba wako.
• Kutsiva mvura : Kana usina mvura mumuviri nekuda kwemanyoka, unogona kupihwa mvura inobuda mumuviri wako kuti ikubatsire kumisa manyoka. Kana kuti, unogona kuudzwa kuti unwe zvinwiwa zvine electrolyte (seJeevani) kuti utsive mvura nemunyu zvinorasika.
• Mavhitamini nezvimwe zvinovaka muviri : Chiremba wako anogona kukukurudzira kuti utore zvinovaka muviri kuti udzorere mavitamini (akadai sevhitamini D, B12, uye iron) uye zvinovaka muviri izvo dumbu rako risingakwanise kupinza zvakanaka. Zvinowanzoitika kuti kushaya zvekudya mumuviri kuitike muchirwere ichi.

Pane migumisiro yakaipa here yekurapwa kwacho?

Ehe, mimwe migumisiro inogona kuitika, kunyanya nemishonga inorwisa mabhakitiriya. Asi izvi hazviitiki kune wese munhu, uye kunyangwe zvikaitika, kazhinji hazvina kuipa.

• Manyoka (kurwadziwa kwemudumbu)
• Dzungu
• Kusvotwa nekurutsa
• Mapundu eganda
• Utachiona hwembiriso (kunyanya munhengo yechikadzi muvakadzi)

Kana chimwe chinhu chakadai chikaitika, zvakakosha kuudza chiremba wako . Vanogona kukwanisa kuchinja mushonga kana kukupa chimwe chinhu kuderedza migumisiro yakaipa.

Chii chinoonekwa nemunhu ane chirwere cheWhipple?

Kufanana nevanhu vazhinji, newewoKana wangotanga kurapwa, unotanga kunzwa kurerukirwa nekukurumidza. Marwadzo emudumbu nemarwadzo emajoini zvinodzikira zvishoma nezvishoma. Zvisinei, zvinogona kutora kusvika makore maviri kuti ura hwako hupore zvizere. Saka, zvakakosha kuti uve nemoyo murefu nekurapwa.

Kazhinji , chirwere chaWhipple chinorapwa zvachose nekurapwa . Zvisinei, dzimwe nguva chirwere chinogona kudzokera shure mushure mekunge kurapwa kwapera. Ndosaka vanachiremba vachiramba vachikuongorora.

Chiremba wako achakukumbira kuti uuye kuzoongororwa nguva nenguva kwenguva yakareba. Semuenzaniso, unogona kukumbirwa kuti uite upper endoscopy:

• Mwedzi mitanhatu yega yega mugore rekutanga rekurapwa.
• Kamwe chete pagore kwemakore matatu anotevera .
• Wobva waita kamwe chete mumakore matatu ega ega kwehupenyu hwako hwese .

Izvi zvinoitirwa kutarisa kana chirwere chacho chadzoka. Saka, musapotsa kushanya kwechiremba zvakare sezvakakurudzirwa nachiremba.

Chirwere cheWhipple chinogona kudzivirirwa here?

Izvozvo zvakaoma kutaura. Nekuti mabhakitiriya anokonzera chirwere cheWhipple ari kwese kwese munharaunda yedu, kunyanya muvhu . Zvisinei, havasi vese vanobatwa nacho vanowana chirwere cheWhipple.

Zvisinei, vanhu vane masoja emuviri asina simba kana avo vanotora mishonga inodzvinyirira masoja emuviri vari panjodzi huru yekubata chirwere ichi. Kana uri mumwe wevanhu ava, zvakanaka kupfeka magirovhosi pese paunoshanda nevhu kana ivhu, uye kugeza maoko ako zvakanaka mushure mebasa . Chenjerera zvikuru kana uri kurima bindu kana kushanda nemhuka.

Ndinozvitarisira sei?

Chinhu chinonyanya kukosha kutora mishonga inorwisa mabhakitiriya sezvakarairwa nachiremba, kwenguva yakazara . Usapotsa zuva, uye tora mushonga kwenguva yakazara yawakarairwa nachiremba. Vanhu vazhinji vachafanira kutora mishonga inorwisa mabhakitiriya kwegore rimwe chete mushure mekuonekwa kuti vane chirwere ichi. Vamwe vanhu vangangoda kutora mishonga inorwisa mabhakitiriya kweupenyu hwavo hwese. Izvi zviri kuna chiremba kuti asarudze.

Kana uine chirwere cheWhipple, muviri wako ungangove uchirasikirwa nezvinovaka muviri zvakawanda zvakakosha . Kunyangwe ukawana zororo kubva mukurapwa, zvakanaka kubvunza nyanzvi yezvekudya kuti uwane zvaunofanira kudya nekunwa . Izvi zvichakubatsira kuwana zvinovaka muviri zvakakodzera uye kuchengetedza huremu hwakanaka.

Ndinofanira kuona chiremba zvakare rini?

Kana ukaramba uine zviratidzo zvechirwere cheWhipple mushure mekunge watanga kurapwa, kana zviratidzo zvikadzoka nguva pfupi mushure mekunge kurapwa kwapera (semuenzaniso, kana uine kurwadziwa mudumbu kana majoini), iva nechokwadi chekuona chiremba wako. Usanonoka. Izvi zvinogona kureva kuti chirwere chacho chadzoka, kana kuti pangave nerimwe dambudziko.

Sei chirwere ichi chichinzi "chirwere cheWhipples"?

Izvi zvakanaka kuziva. Chirwere nemabhakitiriya anokonzera chirwere ichi zvakatumidzwa zita raGeorge H. Whipple, nyanzvi yezvirwere yakatanga kutsanangura zviratidzo muna 1907. Vatsvakurudzi vakazowana mabhakitiriya aikonzera chirwere ichi mushure memakore makumi masere. Vakatumidza mabhakitiriya aya kuti Tropheryma whipplei. Zita iri musanganiswa wemazwi maviri echiGiriki, "trophe" zvinoreva kudya uye "eryma" zvinoreva kuvharika . Zvinoreva kuti zvinokonzera kusamwisa muviri . Harisi zita rakakodzera here?

Mabhakitiriya ari kwese kwese akatipoteredza (uye mukati memiviri yedu). Kazhinji, mabhakitiriya atinosangana nawo zuva nezuva haatinetse. Asi chirwere ichi chisingawanzoitiki, chirwere cheWhipple, chakasiyana zvishoma. Chinokonzerwa nebhakitiriya rinowanikwa muvhu rinonzi Tropheryma whipplei.

Unogona kusangana nehutachiona uhwu (T. whipplei) kubasa kana uri kurima. Zvisinei, havasi vese vanobatwa nahwo vachawana chirwere chaWhipple. Nerombo rakanaka, chirwere ichi chinogona kurapwa kana chikaonekwa nekukurumidza uye chikarapwa nemazvo.

Zvinhu zvinonyanya kukosha zvaunofanira kuyeuka

Chirwere cheWhipple chirwere chinokonzerwa nemabhakitiriya chisingawanzoitiki , asi chinogona kurapwa kana chikarapwa nemazvo .

• Kana zviratidzo zvakaita sekurwadziwa kwemajoini, kurwadziwa mudumbu, manyoka, uye kudzikira kwehuremu zvikaramba zviripo, iva nechokwadi chekuona chiremba. Usazviregeredza.
• Kurapa kunosanganisira kutora mishonga inorwisa mabhakitiriya kwenguva yakareba . Zvakakosha kuitevedzera nemazvo.
• Kana uri kushanda nevhu, kunyanya kana muviri wako usina simba rekudzivirira chirwere, geza maoko ako zvakanaka uye shandisa magirovhosi .
• Kunyangwe chirwere chacho chapora, zvakakosha kuti munhu aende kunoongororwa nguva nenguva ('kutevera') sezvakarairwa nachiremba.

Usatya chirwere ichi. Zvakakosha kuziva zviri kuitika uye kutsvaga mazano echiremba. Hausi wega, uye kune vanachiremba vanogona kukubatsira nedambudziko ripi zvaro. Kana uine kusava nechokwadi, usazeza kutaura nachiremba.

Chirwere cheWhipple , Utachiona hweMabhakitiriya, Utumbu Hudiki, Kusabatwa kweMatumbu, Tropheryma whipplei, Marwadzo eMajoini