Ingaba ingxelo yakho ye-ALT iphezulu? Masifunde nge-ALT (i-Alanine Transaminase) ngendlela elula!

Xa uthatha uvavanyo lwegazi, kusenokwenzeka ukuba ubonile ukuba linexabiso le-ALT okanye i-SGPT. Mhlawumbi ugqirha ukuxelele ukuba eli xabiso liphezulu kancinci kwaye kufuneka ulumke kancinci ngesibindi sakho. Kuqhelekile ukuba uzive usoyika kwaye ukhathazekile xa usiva loo nto. Ngoko ke yintoni le ALT? Kutheni ibaluleke kangaka emzimbeni wethu? Musa ukoyika, masithethe ngayo yonke le nto ngokulula nangokucacileyo.

Ngamafutshane, yintoni i-ALT?

I-Alanine Transaminase (ALT) yi-enzyme emzimbeni wethu. Ngokuchanekileyo, ifana nomsebenzi omncinci ngaphakathi kwiiseli zethu. Umsebenzi wayo ophambili usesibindini . Nangona kunjalo, ukongeza kwisibindi, le enzyme ye-ALT ikhona nakwinani elincinci kwezinye iindawo.

I-enzyme luhlobo lweproteni enceda iinkqubo ezahlukeneyo emzimbeni wethu. Njengokuba kufuneka i-spark plug ukuze uqalise imoto, umzimba udinga aba bancedisi ababizwa ngokuba zii-enzyme ukuze benze izinto ezithile.

Ngoko ke uvavanyo lwegazi lwe-ALT lwenza ntoni?

Uvavanyo lwegazi lwe-ALT lulinganisa ubungakanani be-ALT egazini lakho. Cinga ngesibindi njengendlu, kwaye i-ALT njengezisebenzi ezingaphakathi kuloo ndlu. Ukuba iindonga zale ndlu zonakele nangayiphi na indlela, abasebenzi abangaphakathi bayavuza (oko kukuthi, egazini).

Oku kuthetha ukuba xa iiseli zesibindi sakho zonakele, i-enzyme ye-ALT engaphakathi kwezo seli ikhutshwa egazini. Oku kubangela ukuba amanqanaba e-ALT anyuke xa kuvavanyo lwegazi. Yiyo loo nto oogqirha besebenzisa olu vavanyo ukuze bafumane umbono wempilo yesibindi sakho.

Uvavanyo lwe-ALT alusoloko lwenziwa lodwa. Lwenziwa njengenxalenye yephaneli ye-enzyme yesibindi (LFT) okanye iphaneli ye-metabolic epheleleyo (CMP).

Uvavanyo lwe-ALT lukwaziwa nangamanye amagama aliqela:

• I-Alanine Aminotransferase
• I-SGPT (i-Serum Glutamic-Pyruvic Transaminase)
• I-GPT

Yintoni umahluko phakathi kwe-ALT kunye ne-AST?

Usenokuba uqaphele ukuba kunye ne-ALT, elinye ixabiso elibizwa ngokuba yi-AST nalo lidweliswe kwingxelo yakho. I-AST (i-Aspartate Transaminase) yenye i-enzyme efana ne-ALT. Zombini ezi zinto zinokuqokelelana egazini xa iiseli zonakele.

Kodwa kukho umahluko obalulekileyo apha. I-ALT ifumaneka kakhulu esibindini. Kodwa i-enzyme i-AST ikwafumaneka ngobuninzi entliziyweni, kwimisipha yamathambo, nakwipancreas, ukongeza kwisibindi.

Ngoko ke, xa sithetha ngempilo yesibindi, sicinga ukuba i-ALT ibaluleke kakhulu kwisibindi kune-AST. Nangona kunjalo, oogqirha bajonga zombini ezi xabiso kunye nezinye iziphumo zovavanyo kunye ukuze benze isigqibo esichanekileyo.

Kutheni ucelwa ukuba wenze uvavanyo lwe-ALT?

Kukho izizathu ezintathu eziphambili zokuba ugqirha angakucela ukuba wenze uvavanyo lwegazi oluquka uvavanyo lwe-ALT.

1. Ukuhlolwa ngaphambi kokuba iimpawu zibonakale

Ngamanye amaxesha usenokungabi nazimpawu. Kodwa olu vavanyo lunokukunceda ufumanise ukuba usemngciphekweni wokuba nesifo sesibindi kwixesha elizayo. Ugqirha wakho angacebisa olu vavanyo ukuba unezinye zezi zinto zilandelayo zomngcipheko:

• Ukusela utywala ngokugqithisileyo.
• Ukuba nembali yentsapho yesifo sesibindi.
• Ukuba nesifo seswekile.
• Ukutyeba kakhulu .
• Ukutofa iziyobisi kusetyenziswa iinaliti ezabelwana ngazo nabanye.

2. Ukubeka esweni imeko yempilo (Ukubeka esweni)

Ukuba sele uneengxaki zesibindi, olu vavanyo lwenziwa rhoqo ukuze kubonwe ukuba siya siphucuka na, siya sisiba mandundu, okanye asitshintshi na xa kunyangwa. Kwakhona lwenziwa ukuze kubonwe ukuba kukho umonakalo kwisibindi xa usela amayeza athile anokuchaphazela isibindi.

3. Ukunceda ekuxilongeni isifo (Ukuxilonga)

Ukuba uneempawu ezibonisa ingxaki yesibindi, olu vavanyo lubaluleke kakhulu ukuze kufunyanwe unobangela. Nangona amanqanaba e-ALT ewodwa engenakufumanisa isifo, yinxalenye ebalulekileyo yenkqubo yokuxilonga.

Ngaba kukho naluphi na ulungiselelo olufunekayo ngaphambi kolu vavanyo lwegazi?

Ukuba uvavanyo lwakho lwe-ALT lwenziwa njengenxalenye yoluhlu olupheleleyo lweemvavanyo, ezifana ne-CMP, ungacelwa ukuba uzile ukutya malunga neeyure ezili-10-12 . Ukuzila ukutya kuthetha ukungatyi okanye ukusela nantoni na ngaphandle kwamanzi.

Nangona kunjalo, ukuba wenza uvavanyo lwe-ALT kuphela, ukuzila ukutya akusoloko kuyimfuneko. Nangona kunjalo, kubalulekile ukulandela imiyalelo kagqirha wakho ngokuchanekileyo.

Ukongeza, kubaluleke kakhulu ukuxelela ugqirha wakho malunga namayeza, iivithamini, okanye izongezo ozisebenzisayo, njengoko amanye amayeza anokuchaphazela amanqanaba e-ALT. Yeka ukuthatha nawaphi na amayeza ngaphambi kovavanyo ngaphandle kokuba ugqirha wakho ekuxelele ukuba wenjenjalo. Ungaze uyeke ukuthatha nawaphi na amayeza ngaphandle kwengcebiso kagqirha wakho.

Ekubeni umthambo onzima unokuchaphazela amanqanaba e-ALT, ukuba uwenza rhoqo umthambo onzima, xelela ugqirha wakho ngayo kwangethuba.

Kwenzeka ntoni xa kutsalwa igazi?

Inkqubo yokunikela ngegazi idla ngokuba lula kakhulu.

• Uza kuhlala esitulweni, kwaye umongikazi okanye igosa lezonyango liza kufumana umthambo olungeleyo engalweni yakho ukuze utsale igazi kuwo. Ngokwesiqhelo, umthambo ukhethwa ngaphakathi kwengqiniba.
• Emva koko hlamba kakuhle indawo leyo uze ufake isibulali-ntsholongwane.
• Inaliti encinci kakhulu ifakwa emthanjeni kwaye kuthathwa isampuli yegazi. Ngeli xesha, kusenokuvakala ngathi imbovane encinci iyakuluma.
• Emva kokufaka inaliti, inani elifunekayo legazi liqokelelwa kwityhubhu yovavanyo.
• Nje ukuba igazi litsalwe, inaliti iyasuswa kwaye kufakwa iqhekeza lekotoni kwaye licinezelwe ukunqanda ukopha.
• Faka nje iplasta kwindawo leyo uze ugqibe. Yonke le nkqubo ayifanele ithathe ngaphezu kwemizuzu emihlanu.

Ithetha ukuthini kanye kanye ixabiso le-ALT?

Xa ufumana ingxelo yovavanyo lwakho lwegazi, iqulethe ulwazi oluninzi. Idla ngokuquka:

• Igama lovavanyo olwenziweyo (umz. i-Alanine Transaminase - ALT).
• Iziphumo zakho (ubungakanani begazi lakho).
• Lelo linqanaba eliqhelekileyo lovavanyo.
• Nokuba iziphumo zakho ziqhelekile okanye aziqhelekanga (ziphezulu okanye ziphantsi).

Ithini ixabiso eliqhelekileyo le-ALT?

Uluhlu oluqhelekileyo lwe-ALT lunokwahluka kancinci ukusuka kwilabhoratri ukuya kwenye. Ixabiso elamkelekileyo ngokubanzi liphakathi kweeyunithi ezisi-7 kunye nezingama-56 ngelitha (7 ukuya kuma-56 U/L). Amanqanaba e-ALT kumadoda adla ngokuba phezulu kancinci kunalawo abasetyhini.

Kuthetha ukuthini ukuba inqanaba le-ALT liphezulu?

Amanqanaba aphezulu e-ALT egazini abonisa ukuba kusenokubakho umonakalo okanye ukungasebenzi kakuhle kweeseli zesibindi. Ezinye zezizathu zokuphakama kwamanqanaba e-ALT ziquka:

• Umonakalo wesibindi obangelwa butywala.
• Isifo sesibindi esinamafutha.
• I-Hepatitis (ukudumba kwesibindi).
• I-Cirrhosis (ukudumba kwesibindi).
• Ukusetyenziswa kwamayeza athile anobungozi (anetyhefu) kwisibindi.
• Iithumba zesibindi okanye umhlaza wesibindi.
• Ukuncipha kokunikezelwa kwegazi esibindini (iLiver Ischemia).
• Isinyithi esigqithisileyo emzimbeni (iHemochromatosis).
• Ezinye izifo, ezifana ne-mononucleosis.
• Ezinye iimeko zemfuza ezichaphazela isibindi.

Kodwa khumbula, i-ALT ayifumaneki esibindini kuphela, ngoko ke kunqabile kakhulu ukuba amanqanaba e-ALT anyuswe nokuba iiseli zonakele kwenye indawo.

Kuthetha ukuthini ukuba ne-ALT ephantsi?

Kunqabile ukubona amanqanaba e-ALT esezantsi kunesiqhelo. Kwaye ngokuqhelekileyo ayisiyonto yokukhathazeka ngayo. Nangona kunjalo, kwezinye iimeko, amanqanaba e-ALT anokuba phantsi ngenxa yokunqongophala kwe-vitamin B6 okanye isifo sezintso esingapheliyo. Ukuba iziphumo zakho ziphantsi, ugqirha wakho unokwenza uvavanyo olongezelelweyo ukuze abone ukuba kukho unobangela.

Ngaba kukho ezinye izinto ezinokuchaphazela utshintsho kumanqanaba e-ALT?

Ewe. Ukongeza kwiimeko zempilo, kukho nezinye izinto ezininzi ezinokuchaphazela amanqanaba akho e-ALT. Ugqirha wakho uya kuziqwalasela zonke ezi zinto xa ehlalutya iziphumo zakho.

Yintoni oyenzayo emva koko ukuba ufumana isiphumo esingaqhelekanga?

Ukuba inqanaba lakho le-ALT aliqhelekanga, ugqirha wakho unokucebisa ezinye iimvavanyo ezininzi ukuze afumane unobangela.

• Phinda uvavanyo lwe-ALT.
• Ezinye iimvavanyo zegazi.
• Iiskeni ezifana ne-ultrasound.
• Ukuthatha iqhekeza elincinci lesicwili esibindini ukuze lihlolwe (iBiopsy).

Ukuba amanqanaba akho e-ALT aphezulu kakhulu okanye uneempawu zesifo sesibindi, olu vavanyo lulandelayo kufuneka lwenziwe ngoko nangoko.

Ufanele uye nini kugqirha?

Ukuba ubonakalisa iimpawu zokonakala kwesibindi, ezinje nge-jaundice (ukutyheli kolusu) okanye iintlungu zesisu, bonana nogqirha wakho ngoko nangoko.

Ukuba sele ufunyenwe unesifo sesibindi kwaye kuvela iimpawu ezintsha, nxibelelana nogqirha wakho.

Ukuba unemibuzo okanye iinkxalabo malunga neziphumo zakho ze-ALT, ungaze woyike ukubuza ugqirha wakho ngayo.