Ngaba unengxaki yokunganyamezelani nenyama ebomvu ngendlela engaqhelekanga? Masifunde nge-Alpha-gal Syndrome!

Ngaba wakha wazibuza ukuba kutheni unokuba neempawu ze-allergy emva kokutya inyama ebomvu efana nenyama yenkomo, inyama yehagu, okanye ibhokhwe? Mhlawumbi uza kuba nerhashalala, okanye uza kuba nesisu esibuhlungu, okanye uza kuba nengxaki yokuphefumla. Isenokuvakala ingaqhelekanga, kodwa eneneni inokwenzeka. Namhlanje siza kuthetha nge-allergy engaqhelekanga, kodwa ebaluleke kakhulu. Ibizwa ngokuba yi-Alpha-gal Syndrome.

Yintoni i-Alpha-gal Syndrome? Masiyiqonde ngokulula!

Ngamafutshane, i-Alpha-gal Syndrome (AGS) luhlobo olubi nolungaqhelekanga lokunganyamezelani kokutya oluvela xa usitya inyama ebomvu evela kwizilwanyana ezanyisayo (umzekelo, inyama yenkomo, inyama yehagu, ibhokhwe, inyama yenyamakazi). Idla ngokuvela emva kokulunywa ziintlobo ezithile zeenkizane, ingakumbi ukuba ulunywe izihlandlo ezininzi. Njengoko usazi, iinkizane ziincukuthu ezincinci ezinamathela kwizilwanyana kwaye zifunxe igazi lazo.

Ngoku khangela, ezinye ii-ticks zine-molecule ye-carbohydrate ebizwa ngokuba yi -alpha-gal ematheni azo. Xa le molecule ye-alpha-gal ingena egazini lethu emva kokuluma i-ticks, inokwenza umzimba wethu ube buthathaka ngakumbi kwinyama ebomvu. Okwenzekayo kukuba inkqubo yethu yokuzikhusela komzimba iyaziqonda inyama ebomvu njengento eyingozi emzimbeni ize iqale ukusabela kuyo. Njengotshaba. Yiloo nto ebangela ezo mpawu ze-allergy. Abantu abane-AGS banokuba ne-allergy kungekuphela nje kwinyama ebomvu, kodwa nakwezinye iimveliso ezine-alpha-gal, umzekelo, amayeza athile kunye nesepha.

Ngelishwa, okwangoku akukho nyango lwe-AGS. Kodwa ungakhathazeki. Ungasebenzisana nogqirha wakho ukuze ufumane iindlela zokuphepha izinto ezibangela le ngxaki kwaye uhlale usempilweni.

Yintoni le molekyuli ibizwa ngokuba yiAlpha-gal?

I-Alpha-gal yi-carbohydrate, okanye imolekyuli yeswekile, efumaneka kwiiseli zezilwanyana ezininzi ezincancisayo. Kodwa ayiveliswa ngokwemvelo emzimbeni womntu. Yiyo loo nto imizimba yethu iphazamiseka xa ilunywa yikhalane.

Zeziphi ukutya kunye neemveliso eziqulethe i-Alpha-gal?

Izinto ezinokuba ne-alpha-gal ziquka:

• Inyama ebomvu: Izinto ezifana nenyama yehagu, inyama yenkomo, umvundla, imvana, ibhokhwe, inyathi, kunye nenyama yenkomo.
• Iimveliso zonyango kunye namayeza: Umzekelo, iyeza iCetuximab, elisetyenziselwa umhlaza.
• Iimveliso ezenziwe ngezilwanyana ezanyisayo: igelatin, ubisi lwenkomo, kunye nezinye iisepha, iikhrimu, kunye nezinto zasekhaya zinokuba nazo ezi zinto.

Khawucinge nje, ne-ayisikhrim okanye itshizi oyityayo isenokuba nenani elincinci lale alpha-gal. Ngoko ke kufuneka ulumke kakhulu.

Kwakhona, abanye abantu abane-AGS banokusabela kwiimveliso eziqulethe into ebizwa ngokuba yi-carrageenan. I-Carrageenan yinto edla ngokusetyenziswa ukujiya nokugcina ukutya. Inokufumaneka kwizinto ezifana nobisi lweenati, iimveliso zenyama, kunye neyogathi.

Ngubani onokuba ne-Alpha-gal Syndrome?

Oku kunokwenzeka nakubani na, nokuba ngubani ongazange abe ne-allergy kwinyama ebomvu ngaphambili. Nangona kunjalo, idla ngokubonakala kubantu abadala.

Abantu abachitha ixesha elininzi kwiindawo ezingaphandle apho kuxhaphake khona iimpukane, njengeefama kunye neendawo ezinamahlathi, basengozini enkulu yokufumana i-AGS. ESri Lanka, kulungile nakwabo basebenza kwiindawo ezifana namahlathi okanye iifama apho kukho izilwanyana ukuba baqaphele oku.

Luhlobo luni lweekhakha ezibangela i-AGS?

E-United States, i-lone star tick yeyona ixhaphakileyo enxulunyaniswa ne-AGS. Nangona kunjalo, kukho ezinye iintlobo ze-tick ezinokubangela oku kwiindawo ezahlukeneyo zehlabathi. Umzekelo:

• Ikhakhane elinemilenze emnyama eMelika
• "I-Cayenne tick" eMelika Ephakathi
• I-tick yase-Asia eneempondo ezinde e-Asia

Eyona nto ibalulekileyo kukuba ulumke xa ulunywa yikhalane kwaye ufune iingcebiso zonyango ukuba kuyimfuneko.

Ngaba kukho amanye amagama ale Alpha-gal Syndrome?

Ewe, le inezinye amagama aliqela:

• Ukunganyamezelani kwe-alpha-gal
• Ukunganyamezelani nenyama yezilwanyana ezincelisayo
• Ukunganyamezelani nenyama ebomvu
• Ukunganyamezelani kwenyama ngenxa yetiki

Yintoni ebangela i-Alpha-gal Syndrome? Kutheni oku kusenzeka?

Le meko yaqala ukuchazwa ngo-2009. Ibangelwa kukulunywa ziincukuthu ezithwala imolekyuli ebizwa ngokuba yi-alpha-gal ematheni azo. Nangona uninzi lwezinye izinto ezibangela ukungezwani nokutya zibangelwa ziiproteni, le ibangelwa yimolekyuli yecarbohydrate (iswekile), ngoko ke kuthatha ixesha ukuba impendulo ibonakale. Oko kuthetha ukuba iimpawu zihlala zibonakala phakathi kweeyure ezimbini ukuya kwezintandathu emva kokutya inyama ebomvu . Oku kucingelwa ukuba kungenxa yokuba imizimba yethu ithatha ixesha elide ukugaya iicarbohydrate kuneeproteni.

Oogqirha abakayazi kakuhle ukuba kutheni le alpha-gal ibangela ukuba umntu azive ekhululekile kwinyama ebomvu okanye iyeza lomhlaza elikhankanyiweyo ngaphambili iCetuximab. Ngokufanayo, kusaphandwa ukuba kutheni abanye abantu benesifo se-AGS ngelixa abanye bengenaso.

Zithini iimpawu ze-Alpha-gal Syndrome?

Iimpawu zoku zingahluka kakhulu. Abanye abantu banokufumana iimpawu ezibuthathaka kakhulu, ngelixa abanye banokufumana iimpawu ezinzima nezisongela ubomi.

Ezona mpendulo zixhaphakileyo kulusu zezi:

• Ukurhawuzelelwa kakhulu lusu (oogqirha bathi kukurhawuzelelwa)
• Ubomvu bolusu kunye nokudumba (okubizwa ngokuba yi-flushing)
• Ukuqhambuka kwesikhumba, amadyungudyungu afana ne-chickenpox (oku kubizwa ngokuba yi-urticaria okanye ii-hives)
• Ukudumba kwemilebe, iinkophe, umphimbo, ulwimi, okanye ubuso (oku kubizwa ngokuba yi-angioedema)

Iingxaki zenkqubo yokugaya ukutya nazo zinokubakho, ngamanye amaxesha zezi:

• Intlungu yesisu, iintlungu zesisu
• Urhudo
• Isitshiso sentliziyo, ukungagayi kakuhle kokutya
• Ukungagayi kakuhle ukutya, ukungagayi kakuhle ukutya (dyspepsia)
• Ukuqaqamba kwemisipha
• Isicaphucaphu okanye ukuhlanza

I-Alpha-gal syndrome inokubangela iimpawu ezinxulumene nemiphunga. Ezi ziyingozi kakhulu:

• I-Anaphylaxis: Le yeyona iyingozi kakhulu. Yi-allergy enzima enokuthintela ukuphefumla kwaye ibe yingozi ebomini. Ukuba unengxaki yokuphefumla, yiya esibhedlele esikufutshane ngoko nangoko okanye utsalele umnxeba ku-911.
• Ukukhwehlela
• Ubunzima bokuphefumla, ukuphefumla okunzima (ukuphelelwa ngamandla)
• Ukuphefumla

Kusenokubakho nezinye iimpawu:

• I-Arthritis (oku akuqhelekanga kangako)
• Ukubetha kwentliziyo, uzive ngathi isifuba sakho siyabetha
• Uxinzelelo lwegazi oluphantsi (uxinzelelo lwegazi oluphantsi)
• Isifo sokusebenza kweseli ye-mast, isifo esingaqhelekanga senkqubo yomzimba yokuzikhusela (naso sinqabile)

Ngaba kukho ezinye izinto ezichaphazela iimpawu?

Ewe, iimpawu zakho zinokutshintsha ngokuhamba kwexesha. Iimpendulo ze-allergy zinokuba qatha ngakumbi okanye zenzeke rhoqo ukuba ulunywe yi-tick entsha. Kwezinye iimeko, izinto ezinje ngokusela utywala, umsebenzi womzimba, kunye nokuzilolonga nazo zinokuchaphazela indlela umzimba wakho osabela ngayo kwi-alpha-gal.

Kutheni kunzima kangaka ukuxilonga i-Alpha-gal Syndrome?

Oku kunokuba nzima kancinci ukukubona. Kukho izizathu ezahlukeneyo.

Esinye sesokuba iimpukane aziziva ntlungu xa ziluma, ngoko ke abantu abaninzi abazi nokuba zilunywe yimpukane.

Kwakhona, ngokungafaniyo nezinye izinto ezibangela ukungezwani nokutya, ukusabela kwi-alpha-gal kuthatha iiyure ukuba kuvele . Ngamanye amaxesha iimpawu zibonakala ezinzulwini zobusuku emva kwesidlo sangokuhlwa. Ngubani onokucinga ukuba kungenxa yenyama abayityileyo kusasa okanye ngexesha lesidlo sasemini?

Kwakhona, ayilo lonke ixesha xa i-alpha-gal ityiwa, kukho impendulo, kwaye neempawu azisoloko zibonakala ngendlela efanayo.

Ngenxa yezi zinto, kunokuba nzima kancinci kuwe nakugqirha wakho ukufumanisa ukuba oku kuyinto eyahlukileyo kwi-alpha-gal.

Oogqirha bayixilonga njani kanye kanye le nto?

Ukuze kufunyaniswe i-AGS, ugqirha wakho okanye ingcali ye-allergy iya kujonga ngononophelo iimpawu zakho, imbali yezonyango, kunye novavanyo lomzimba. Ukongeza, uvavanyo lwe-allergy lunokwenziwa ukuqinisekisa ukuxilongwa. Ezona ziphambili ziquka:

• Uvavanyo lwegazi: Olu vavanyo lujonga ukuba kukho ii-antibodies ze-immunoglobulin-E (IgE) egazini, ezenziwa yinkqubo yethu yomzimba yokulwa ne-alpha-gal.
• Uvavanyo lokuhlaba ulusu: Kule meko, kubekwa inani elincinci le-allergen phezu kolusu ukuze kubonwe ukuba kukho ukusabela na.

Ukuba ucinga ukuba unokuba ne-AGS, bonana nogqirha ngokukhawuleza. Okukhona uyiqaphela ngokukhawuleza, kokukhona kulula ukuphepha izinto ezibangela i-allergens nokuthintela iingxaki.

Ngaba ikho indlela epheleleyo yokunyanga oku?

Njengoko bekutshiwo ngaphambili, okwangoku akukho nyango lwe-Alpha-gal Syndrome. Kodwa ungakhathazeki. Ukuba ifunyenwe kwangethuba, wena nogqirha wakho ninokusebenzisana ukwenza isicwangciso solawulo esifanela iimfuno zenu.

Iphathwa njani le nto?

Unyango oluphambili lomntu one-AGS kukuphepha ngokupheleleyo ukutya kunye neemveliso ezine-alpha-gal . Ukongeza, amayeza anikwa ukulawula iimpawu ukuba into efana nale ityiwe ngengozi.

Oogqirha banokucebisa amayeza anjenge- antihistamines okanye i-adrenaline injector xa kusetyenziswe ngokukhawuleza. Kwiimeko ezinzima ezifana ne-anaphylaxis, le epinephrine injector inokusindisa ubomi. Ezinye iindlela zonyango zixhomekeke kwiimpawu zakho. Umzekelo, isisombululo se-cromolyn somlomo sinokunceda kwiingxaki zokugaya ukutya.

Ndingayinciphisa njani ingozi yokuba ne-Alpha-gal Syndrome?

Eyona ndlela ilungileyo yokuzikhusela kungekuphela nje kwi-AGS, kodwa nakwezinye izifo ezithwalwa ziincukuthu, kukuphepha ukulunywa ziincukuthu . Zininzi izinto onokuzenza ukuze wenze oku:

• Ziphephe iindawo apho kukho iimpukane: Ziphephe ukuhamba ngokungeyomfuneko emahlathini, kwiindawo ezinengca, nakwiindawo ezinemithi emininzi, ingakumbi apho kukho izilwanyana. Kwakhona lumka xa usebenza egadini.
• Gquma kakuhle: Nxiba impahla enemikhono emide, ibhulukhwe ende. Beka iikawusi phezu kwebhulukhwe yakho, nxiba izihlangu. Ukuba kunokwenzeka, sebenzisa umnqwazi kunye neeglavu.
• Sebenzisa izinto zokugxotha izinambuzane: Sebenzisa into yokugxotha izinambuzane evunyiweyo ngugqirha. Ezinye zingafakwa empahleni. Iimveliso ezine-permethrin zingafakwa empahleni.
• Jonga amathegi (jonga uphawu):Emva kokubuya ngaphandle, zihlole wena nezilwanyana zasekhaya zakho ukuba azinazo na iimpukane. Kukwangumbono olungileyo ukuhlamba.
• Ukuba ubona ikhala, yisuse ngokukhawuleza: Sebenzisa ii-tweezers ukuze ubambe intloko okanye umlomo wekhala, uze uyitsale ngononophelo uye phezulu ngaphandle kokuyityumza. Emva koko faka isibulali-ntsholongwane kuloo ndawo.

Ukuba une-Alpha-gal Syndrome, zeziphi ukutya, iziselo, kunye neemveliso omele uziphephe?

Abantu abaninzi abane-AGS kufuneka baziphephe ngokupheleleyo iimveliso zenyama ebomvu kunye nenyama ebomvu. Nangona kunjalo, ayinguye wonke umntu osabela ngendlela efanayo kwi-alpha-gal. Ngoko ke kungcono ukuthetha nogqirha wakho okanye ingcali ye-allergies ukuze ufumane ukuba yintoni kanye kanye ebangela ukuba uzive unesifo.

Izinto ekufuneka uziphephe ngokubanzi zezi:

• Inyama ebomvu: inyama yenkomo, imvana, ibhokhwe, inyama yenkomo, umvundla, inyathi, inyama yehagu.
• Iimveliso ezenziwe ngenyama ebomvu: izongezo zokutya, ubisi, ukhilimu, i-ayisikhrim, amafutha ezilwanyana (i-lard), itshizi.
• Iimveliso zokhathalelo lolusu ezenziwe ngenyama: iimveliso eziqulethe i-collagen, i-lanolin, i-gelatin, i-glycerin.
• Ezinye iimveliso: Thetha nogqirha wakho malunga namayeza owasebenzisayo. Kwakhona, iivalvu zentliziyo ezivela kwiihagu okanye kwiinkomo, i-mesh yotyando, kunye nezinye izitofu zinokubangela ii-allergy.

Kuza kwenzeka ntoni emva koko? Siza kuphila njani nale nto?

Ukuba ulandela imiyalelo kagqirha wakho ngononophelo kwaye uphepha izinto ezibangela ukuba ube ne-allergies, ungaphila kakuhle ne-AGS. Ugqirha wakho uya kukunceda ufumane iindlela zokunciphisa umngcipheko we-allergy.

Eyona nto ibalulekileyo kukuthatha amanyathelo okuphepha ukulunywa ziincukuthu , njengoko ukulunywa ziincukuthu rhoqo kunokwenza ukuba ii-allergy zibe mandundu.

Ufanele ufune nini ingcebiso kagqirha?

Ukuba ubonakalisa iimpawu ze-AGS, bonana nogqirha we-allergies okanye ugqirha oqhelekileyo ngoko nangoko ukuze kwenziwe isicwangciso sonyango esifanelekileyo kuwe.

Umyalezo Wokuya Ekhaya

Kulungile, ngoko ke i-Alpha-gal Syndrome (AGS) esithethe ngayo namhlanje yimpendulo enzima ye-allergy kwinyama ebomvu ebangelwa kukulunywa ziincukuthu. Kunokuba nzima ukuyifumanisa, njengoko iimpawu zibonakala emva kweeyure. Kwaye okwangoku akukho nyango lwayo.

Kodwa ungakhathazeki! Ukuba uyiqaphela kwangethuba, landela icebiso likagqirha wakho, uphephe ukutya okuyingozi kunye neemveliso, kwaye uzikhusele kwiincukuthu, nawe ungahlala usempilweni kwaye uphilile. Ukuba unale mpawu, qiniseka ukuba ubona ugqirha.

"I-Alpha-gal Syndrome, Ukunganyamezelani nenyama ebomvu, Izifo ezithwalwa ziincukuthu, Ukunganyamezelani nokutya, Iimpawu ze-Allergy, Ukukhuselwa kwiincukuthu