Mhlawumbi uyazi ukuba i-Ankylosing Spondylitis (AS) yimeko ebuhlungu kakhulu ebangela iintlungu nokuqina komqolo kunye namalungu. Xa unyanga oku, kubaluleke kakhulu ukuzilolonga nokusebenzisa amayeza achazwe ngugqirha wakho ngokuchanekileyo. Nangona kunjalo, ngamanye amaxesha la mayeza anokubangela iziphumo ezingezizo. Kodwa ungoyiki. Asinguye wonke umntu ofumana ezi ziphumo, kwaye amava omntu ngamnye ahlukile. Eyona nto ibalulekileyo kukuthetha nogqirha wakho kwaye ukhethe indlela yonyango esebenza kakuhle kuwe kwaye ineziphumo ezingezizo ezimbalwa.
Iipilisi zokunciphisa iintlungu zodidi lokuqala: ii-NSAID
Oogqirha badla ngokunika olu hlobo lwamayeza kuqala kwi-AS. Siwabiza la mayeza angengo-steroidal Anti-inflammatory, okanye ii-NSAIDs ngamafutshane. La mayeza asebenza ekunciphiseni ukudumba kunye nentlungu emalungeni. Usenokuba ukhe weva ngala magama:
- I-Ibuprofen (Advil, Motrin)
- I-Naproxen (iNaprosyn)
- Indomethacin (Indocin, Tivorbex)
- I-Celecoxib (iCelebrex)
Nangona kunjalo, xa la mayeza ethathwa ngeedosi eziphezulu ixesha elide, umaleko wokukhusela we-mucus ngaphakathi esiswini sethu unokuba mncane, nto leyo enokubangela ezinye iziphumo ebezingalindelekanga.
| Iziphumo ebezingalindelekanga ezinokubakho ze-NSAIDs |
|---|
| Isitshiso sentliziyo |
| Ukudumba kwengaphakathi lesisu |
| Izilonda zesisu kunye nokopha kwegazi |
| Ukuba unesifo sentliziyo esele sikhona, umngcipheko wakho wokuhlaselwa sisifo sentliziyo okanye isifo sohlangothi uyanda. |
Eyona nto ibalulekileyo kukusebenzisa eli yeza kuphela ngokwedosi kwaye ixesha elichazwe ngugqirha wakho. Ukuba uziva ukhathazekile sisisu, xelela ugqirha wakho ngoko nangoko.
Indlela yonyango yanamhlanje: I-Biologics (IL-17 Inhibitors)
La luhlobo lwamayeza oluphucukileyo kancinci nolukhethekileyo. Asebenza ngokujolisa kwikhemikhali ethile emzimbeni ebangela ukudumba nokuthintela ukusebenza kwayo. I-Secukinumab (Cosentyx) kunye ne-Ixekizumab (Taltz) zezinye zezi ntlobo zamayeza. Zibizwa ngokuba zii-IL-17 inhibitors . Nangona ezi ziindlela zonyango ezisebenzayo kakhulu, zinokubangela ezinye iziphumo ebezingalindelekanga.
| Iziphumo ebezingalindelekanga ezinokubakho zebhayoloji | Kalula nje... |
|---|---|
| Isifo samathumbu esivuthayo (IBD) | Eli yeza linokubangela ukuqala okutsha kwe-IBD okanye iimpawu ezibi ngakumbi kumntu osele enayo. |
| Iintsholongwane | Ezi zinokunciphisa ukusebenza kwenkqubo yomzimba yokuzikhusela ukuya kuthi ga kwinqanaba elithile, nto leyo enokunyusa kancinci umngcipheko wokufumana izifo ezifana nomkhuhlane kunye nomkhuhlane. |
| Umngcipheko womhlaza | Nangona uphando lwezilwanyana lubonise umngcipheko womhlaza, akukacaci ukuba lo mngcipheko ungakanani ebantwini. Musa ukoyika ngokungeyomfuneko, kodwa thetha nogqirha wakho ngawo. |
Izithinteli zeJAK zithathwa njengeepilisi
Olu lolunye uhlobo lwamayeza anciphisa ukudumba. I-Tofacitinib (Xeljanz) yenye yala mayeza athathwa njengepilisi. La mayeza anokuba nemiphumo emibi.
- Intloko ebuhlungu
- Urhudo
- Ukudinwa
- Ukubetha kwentliziyo
- Ingozi yokonakala kwesibindi
Ngoko ke, ugqirha wakho uza kujonga impilo yakho rhoqo ngelixa usebenzisa la mayeza.
Ii-Corticosteroids, ezinikwa ngamaxesha athile kuphela
La mayeza adla ngokuba ngamayeza exesha elide e-AS. Nangona kunjalo, ukuba intlungu kunye nokudumba kwilungu elithile kuyanda ngequbuliso (ukuqhambuka) , i-corticosteroid inokunikwa elo lungu kuphela.Ugqirha usenokugqiba ekubeni akunike inaliti. Ezi ziphumo bezingalindelekanga zinokwenzeka xa uzisebenzisa ixesha elide. Kodwa inaliti yexesha elifutshane ayizukubangela zonke ezi zinto. Kodwa kulungile ukwazi.
| Iziphumo ebezingalindelekanga ezinokubakho ze-corticosteroids (ingakumbi xa zisetyenziswa ixesha elide) | |
|---|---|
| Ukwanda komnqweno wokutya kunye nokunyuka kobunzima | Ukugruzuka lula |
| Utshintsho lweemvakalelo | Ubuthathaka bemisipha |
| Umbono ofipheleyo | Ukuncipha kwamandla okulwa nosulelo |
| Ukudumba kobuso okanye i-acne | Igazi elonyukayo |
| Isifo seswekile okanye ukuba mandundu kwesifo seswekile esikhoyo | Ukungalali |
Amanye amayeza (iSulfasalazine kunye neMethotrexate)
I-Sulfasalazine
Ukuba ii-NSAID azilawuli iintlungu zamalungu akho (ingakumbi emagxeni akho, ezingalweni, nasemilenzeni), ugqirha wakho unokukunika iyeza elibizwa ngokuba yiSulfasalazine (Azulfidine). Oku kunemiphumo emibi engaqhelekanga.
- Intlungu yamalungu
- Ifiva
- Intloko ebuhlungu
- Ukwanda kovakalelo lolusu kwilanga
- Ulusu olurhawuzelelayo okanye ukurhawuzelela
- Isicaphucaphu
I-Methotrexate
Eli yeza lingasetyenziswa njengepilisi okanye njengenaliti. Ugqirha ngokuqinisekileyo uya kucebisa ukuba kuthathwe i-vitamin ye-folic acid ngelixa esela le vithamini. Isizathu soku kukuba iziphumo ebezingalindelekanga zeMethotrexate zinokuncitshiswa kakhulu yi-folic acid.
- Isicaphucaphu nokuhlanza
- Izilonda zomlomo
- Intloko ebuhlungu
- Ndiziva ndidiniwe
Yintoni omawuyenze xa kuvela ezi ziphumo ebezingalindelekanga?
Le yeyona nxalenye ibalulekileyo. Ukuba ufumana naluphi na utshintsho emzimbeni wakho, iimpawu ezintsha, okanye ukungonwabi ngenxa yamayeza owaselayo kwi-AS, into yokuqala neyona ilungileyo ekufuneka uyenze kukwazisa ugqirha wakho ngoko nangoko.
Ungaze uyeke ukuthatha amayeza akho okanye utshintshe umthamo ngokwakho. Ukwenza njalo kunokwenza kube nzima ukulawula imeko yakho.
Ugqirha wakho uza kukunceda. Angakunceda:
- Umthamo wamayeza owanikwayo uza kuncitshiswa kancinci .
- Uza kutshintshelwa kwelinye iyeza .
- Kunye namayeza akhoyo ngoku, kuza kunikwa elinye iyeza lokulawula iziphumo ebezingalindelekanga .
Ingongoma apha kukuba wena nogqirha wakho nisebenzisane njengeqela ukuze nifumane unyango olungcono olulungele umzimba wakho, oluneziphumo ezibi ezincinci, kwaye olungenamngcipheko mkhulu. Ngoko ke ungoyiki nto, kwaye uthethe nogqirha wakho ngayo yonke into ngokukhululekileyo.
Umyalezo Wokuya Ekhaya
- Ayizizo zonke amayeza e-Ankylosing Spondylitis (AS) abangela iziphumo ebezingalindelekanga, kwaye ayinguye wonke umntu oza kuba neziphumo ebezingalindelekanga.
- Ukuqaphela iziphumo ebezingalindelekanga yenye yezona ndlela zilungileyo zokuzilawula.
- Ukuba ufumana naluphi na uvakalelo olubi ngenxa yamayeza akho, ungaze wenze izigqibo wedwa, kwaye thetha nogqirha wakho rhoqo.
- Injongo kagqirha wakho kukufumana unyango olukulungeleyo kwaye oluneziphumo ebezingalindelekanga ezimbalwa.
- Kubaluleke kakhulu ukuya kwiikliniki ngexesha kwaye uxoxe rhoqo ngemeko yakho nogqirha wakho.
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