Umzimba wethu yindlela emangalisayo. Ufana nenqaba ekhuselweyo kakuhle. Le nqaba inomkhosi wayo oqaphela kwaye utshabalalisa iintshaba ezifana neentsholongwane kunye nosulelo. Oku sikubiza ngokuba yinkqubo yomzimba yokuzikhusela. Kodwa, khawucinge ukuba bekuya kwenzeka ntoni ukuba amanye amajoni kumkhosi wethu ebenokudideka kancinci, engakwazi ukubona ukuba ngubani umhlobo okanye utshaba, aze aqale ukuhlasela iiseli eziphilileyo zomzimba wethu? Yiyo loo nto la 'ma-autoantibodies' eyiyo.
Ngamafutshane, zithini ii-antibodies kunye nee-autoantibodies?
Masiqonde oku ngolu hlobo.
- Ii-antibodies: La ngamajoni anobuchule naqeqeshweyo kwinkqubo yethu yokuzikhusela. Xa into engafunekiyo, njengentsholongwane, intsholongwane, okanye ibhaktheriya, ingena emzimbeni, la majoni ayaluchonga utshaba, alujolise kulo, aze alutshabalalise. Yile nto ifanele yenzeke emzimbeni ophilileyo.
- Ii-Autoantibodies: La ngamajoni alahlekileyo, adidekileyo phakathi kwala majoni anobuchule. Endaweni yokutshabalalisa iintshaba zangaphandle, ngempazamo bacinga ngeeseli zethu eziphilileyo kunye nezicubu "njengeentshaba" baze baqale ukuzihlasela. Kufana nokuphosa amatye endlwini yethu.
Xa amalungu omzimba wethu eqala ukonakala ngale ndlela, oko kunokukhokelela kwizifo ezahlukeneyo zokuzikhusela komzimba.
Ziziphi izifo ezinokubangelwa yi-autoantibodies?
Ngenxa yokuba ii-autoantibodies zihlasela amalungu ahlukeneyo omzimba, izifo ezahlukeneyo zinokuvela kuxhomekeke kwindawo apho umonakalo wenzeka khona. Usenokuba ukhe weva ngezinye zezi.
| Igama lesifo (Isifo) | Ingcaciso elula |
|---|---|
| Uhlobo lwe-1 lwesifo seswekile | Ukonakala kweeseli ezivelisa i-insulin kwi-pancreas. |
| Irheumatoid arthritis | Intlungu, ukudumba, kunye nokuqina kwamalungu. |
| I-Lupus | Isifo esinokuchaphazela amalungu amaninzi, njengolusu, amalungu, izintso kunye nengqondo. |
| I-Multiple Sclerosis (MS) | Ukonakala kwemithambo-luvo engqondweni nasemgogodleni. |
| I-Psoriasis | Amabala abomvu, anamaxolo eluswini ngenxa yokukhula ngokukhawuleza kweeseli zesikhumba. |
| Isifo samangcwaba | I-Hyperthyroidism. |
Olu luhlu luyimizekelo embalwa nje. Ukongeza, kukho nezinye izifo ezininzi ezinokubangelwa yile meko.
Kutheni imizimba yethu ingenza into engalunganga ngolu hlobo?
Oogqirha kunye nososayensi abakakwazi ukutsho ngokuqinisekileyo ngokupheleleyo ukuba yintoni unobangela woku. Nangona kunjalo, kukho izinto ezibalulekileyo ekucingelwa ukuba zinegalelo ekudalweni kwezi autoantibodies.
- Iintsholongwane: Ezinye izifo ezibangelwa yintsholongwane okanye iintsholongwane zinokubeka uxinzelelo olukhulu kwinkqubo yethu yomzimba yokuzikhusela, nto leyo ebangela ukuba ingasebenzi kakuhle. Ngamaxesha anje, kunokwenzeka ukuba ii-autoantibodies ziqale ukuveliswa.
- Izinto ezibangela imeko-bume: Kucingelwa ukuba imeko-bume esihlala kuyo, ukuchatshazelwa kungcoliseko lomoya, kunye nokuchatshazelwa ziikhemikhali ezithile nazo zinokuba zizinto ezibangela oko.
- Ufuzo: Ukuba umama wakho, utata, okanye ilungu losapho olusondeleyo linesifo sokuzikhusela komzimba, usenokuba nomngcipheko wokuba nale meko. Kodwa oko akuthethi ukuba ngokuqinisekileyo uza kuba nayo. Ngumngcipheko nje.
Ngamanye amaxesha, ii-autoantibodies zinokuvela ngaphandle kwesizathu esicacileyo.
Ufumanisa njani ukuba une-autoantibodies? Zithini iindlela zonyango?
Into ebalulekileyo apha kukuba ukuba ne-autoantibodies emzimbeni wakho akuthethi ukuba unesifo. Abanye abantu banazo ezi zinto emizimbeni yabo kodwa baphila ubomi obusempilweni ngaphandle kweempawu.
Ii-Autoantibodies azisisifo, kodwa "ziindlela" ezinceda ekuchongeni isifo.
Ukuba ubonakalisa iimpawu ezithile (umz., iintlungu zamalungu, ukudinwa kakhulu, utshintsho lolusu), ugqirha wakho unokwenza uvavanyo lwegazi oluninzi ukujonga olu hlobo lwee-autoantibodies.
Umzekelo:
- Ukuba uneempawu ze-rheumatoid arthritis, ugqirha wakho uza kujonga igazi lakho ukuba alina-autoantibodies ebizwa ngokuba yi-`(Rheumatoid factor)`.
- Ukuba ufumana amahlwili egazi ngequbuliso okanye iingxaki ngexesha lokukhulelwa, unokuvavanywa ii-autoantibodies ezifana ne-``Lupus anticoagulant```.
Xa kufikwa kunyango, unyango alukho kwi-autoantibodies ngokwazo, kodwa lulolwesifo se-autoimmune kunye neempawu zaso ozifumanayo ngenxa yezo autoantibodies.
Izifo ezininzi ze-autoimmune azipheli. Oko kuthetha ukuba zihlala ubomi bonke. Kodwa ungakhathazeki. Ngeengcebiso zonyango ezifanelekileyo kunye nonyango, abantu abaninzi banokulawula iimpawu zabo kwaye baphile ubomi obuqhelekileyo. Kusenokufuneka ubone ugqirha ochwephesha kwezi zifo (ingcali yamathambo).
Ndifanele ndimbone nini ugqirha?
Ukuba uneempawu emzimbeni wakho ocinga ukuba zintsha okanye ezingaqhelekanga (iintlungu, ukudumba, utshintsho lolusu) ezihlala zikho, okanye ukuba ziya zisiba mandundu kancinci kancinci, qiniseka ukuba ubona ugqirha.
Akukho mntu wazi umzimba wakho ngcono kunawe. Ngoko ke musa ukuyityeshela indlela ovakalelwa ngayo, okanye naziphi na iimvakalelo ezingaqhelekanga. Ukuba sele uyazi ukuba unesifo sokuzikhusela komzimba kwaye uziva ngathi iimpawu zakho ziya zisiba mandundu, thetha nogqirha wakho ngaloo nto.
Umyalezo Wokuya Ekhaya
- Ii-Autoantibodies ziyinxalenye yenkqubo yethu yomzimba yokuzikhusela ehlasela iiseli zethu eziphilileyo ngempazamo.
- Ukuba une-autoantibodies emzimbeni wakho akuthethi ukuba unesifo. Yindlela nje enceda oogqirha ukuba bafumanise isifo.
- Nangona kungekho sizathu sichanekileyo sale meko, usulelo, imeko-bume, kunye neempawu zemfuza zinokudlala indima.
- Unyango alukho kwi-autoantibodies, kodwa lulolwesifo esisisiseko.
- Ukuba uneempawu ezingaqhelekanga nezihlala ixesha elide, bona ugqirha wakho ngoko nangoko ukuze akunike icebiso. Ungaze uyityeshele loo nto.
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