Sonke siyazi ukuba ukulwa nomhlaza akuyonto ilula. Kodwa ngokuhambela phambili kwesayensi yezonyango, kuye kwaziswa unyango olutsha nolunamandla emhlabeni ukuze lusincede kule mfazwe. Usenokucinga ukuba olu nyango luyinkimbinkimbi kwaye luyoyikisa. Kodwa ithemba eliziswa lulo likhulu kakhulu. Namhlanje siza kuthetha ngonyango olutsha olunjalo. Olu nyango lubizwa ngokuba yi-Axicabtagene Ciloleucel.
Yintoni i-Axicabtagene Ciloleucel?
Ngamafutshane, olu lunyango lwezakhi zofuzo . Olu asilo pilisi okanye ikhaphu eqhelekileyo oyinikwayo. Olu lwenziwe ngeeseli zakho zenkqubo yomzimba yokuzikhusela .
Cinga ngeeseli zomzimba wakho zokuzikhusela njengomkhosi okhusela ilizwe. Ngamanye amaxesha, iintshaba ezibizwa ngokuba ziiseli zomhlaza ziyazimela kulo mkhosi, ziwakhohlise zize zisasazeke emzimbeni wonke.
Oku kwenziwa lolu nyango lwe-Axicabtagene Ciloleucel (igama lophawu: YESCARTA).
1. Okokuqala, igazi liyathathwa emzimbeni wakho kwaye iiseli zakho zomzimba (ii-T-cells) zahlulwe kuwo.
2. Emva koko, ezo seli zithunyelwa kwilabhoratri ekhethekileyo kwaye ziguqulwe ngokwemfuza. Kufana nokunika amajoni ethu uqeqesho olukhethekileyo kunye nesixhobo esikhethekileyo (esibizwa ngokuba yiChimeric Antigen Receptor okanye iCAR) esinokuzibona ngokuchanekileyo iintshaba.
3. Izigidi zeeseli eziqeqeshwe ngale ndlela kwaye zinikwe amandla amakhulu zibuyiselwa emzimbeni wakho ngomthambo.
4. Ngoku la majoni anamandla anokufumana, achonge, aze atshabalalise iiseli zomhlaza ezifihliweyo emzimbeni.
Olu nyango okwangoku lusetyenziswa kakhulu ekunyangeni iintlobo ezahlukeneyo ze-lymphoma. Umzekelo, lusebenza kakhulu kwiimeko ezifana ne- large B-cell lymphoma kunye ne-follicular lymphoma .
Yintoni omele uyixelele iqela lakho lezonyango ngaphambi kokuba uqale unyango?
Ekubeni olu nyango lukhethekileyo, kubalulekile ukuba wazise ugqirha wakho ngembali yakho epheleleyo yempilo. Qiniseka ukuba uyabaxelela ukuba unayo nayiphi na kwezi meko zilandelayo:
- Isifo sentliziyo: Ukuba unesifo sentliziyo.
- Ukukhubazeka: Ukuba ukhe waba nestroke ngaphambili.
- Usulelo: Ukuba okwangoku unesulelo emzimbeni (njengomkhuhlane, ukukhwehlela, umkhuhlane).
- Isifo sezintso okanye sesibindi: Ukuba unengxaki yezintso okanye yesibindi.
- Izifo zemiphunga: Ukuba unengxaki yokuphefumla efana ne-asthma.
- Ukuba usandul’ ukufumana okanye uza kufumana isitofu sokugonya: Ufanele ukwazi oku, ingakumbi malunga nesitofu sokugonya esiphilayo .
- Ukunyamalala/Ukuxhuzula: Ukuba ukhe waxhuzula ngaphambili.
- Ii-Allergies: Ukuba une-allergy kule yeza okanye naliphi na elinye iyeza, ukutya, okanye idayi.
- Ukuba ukhulelwe okanye uzama ukukhulelwa: Oku kubaluleke kakhulu.
- Ukuba ungumama oncancisayo.
Ukuthetha ngokukhululekileyo nogqirha wakho ngayo yonke le nto kubaluleke kakhulu kwimpumelelo yonyango lwakho kunye nokhuseleko lwakho.
Izinto ekufuneka ziqwalaselwe ngexesha nasemva konyango
Usenokuvavanywa igazi rhoqo ngelixa ufumana olu nyango. Kwakhona, lumka kakhulu kwezi zinto zilandelayo:
Zikhusele kwiintsholongwane
Emva kolu nyango, amandla omzimba wakho okulwa nosulelo anokuncipha kancinci. Ke ngoko, ukuba ufumana iimpawu ezinje ngomkhuhlane, ukubanda, umphimbo obuhlungu, kunye nokukhwehlela , musa ukuzenza unyango. Fowunela ugqirha wakho ngoko nangoko ukuze ufumane ingcebiso. Kwakhona, zama ukuhlala kude nabantu abagulayo.
Ukuqhuba kunye nomsebenzi ofuna ingqalelo
Eli yeza lingakwenza uzive ulele, unesiyezi, okanye unentloko ebuhlungu. Ngoko ke, kuphephe ukuqhuba, ukusebenzisa oomatshini, okanye ukwenza nantoni na efuna ukugxininiswa ude wazi kakuhle ukuba eli yeza likuchaphazela njani.
Amanye amanqaku ambalwa abalulekileyo
- Musa ukunikela ngegazi ngelixa usebenzisa olu nyango.
- Musa ukukhulelwa ngelixa usebenzisa olu nyango. Ukuba ungumfazi, uceba ukukhulelwa, okanye ucinga ukuba ukhulelwe, xelela ugqirha wakho ngoko nangoko kuba kukho umngcipheko weziphumo ebezingalindelekanga ezibi kumntwana ongekazalwa.
- Thetha nogqirha wakho malunga nomngcipheko wokufumana ezinye iintlobo zomhlaza ngenxa yolu nyango.
Zithini iziphumo ebezingalindelekanga ezinokubakho?
Njengakwezinye iindlela zonyango ezinamandla, kukho iziphumo ebezingalindelekanga. Ezinye zezi kufuneka zixelwe ngoko nangoko, ngelixa ezinye zingembi kangako. Masizichaze.
| Imiphumela | Inkcazo |
|---|---|
| 🚨 Yazisa ugqirha wakho okanye iYunithi yoNyango oluNgxamisekileyo (ETU) yesibhedlele ngoko nangoko | |
| Iimpendulo ze-allergy | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe okanye ulwimi. |
| Ubunzima bokuphefumla | Ukuphefumla kancinci, ubunzima esifubeni. |
| Ukudideka kwengqondo | Ukulahlekelwa yinkumbulo, ukudideka, ubunzima bokuthetha okanye ukuqonda oko kuthethwa ngabanye abantu. |
| Utshintsho kwisantya sentliziyo | Ukubetha kwentliziyo ngokukhawuleza okanye ngokungangqalanga. |
| Iimpawu zosulelo | Umkhuhlane, ukubanda, ukukhohlela, umphimbo obuhlungu, usulelo lomchamo. |
| Uxinzelelo lwegazi oluphantsi | Ukudinwa, ukubona izinto zingacacanga, ukuquleka, ukudinwa kakhulu. |
| Iimpawu zeeseli ezibomvu zegazi ezisezantsi | Uburhabaxa, ukudinwa kakhulu, ubunzima bokuphefumla. |
| Isisu esibuhlungu | Ukucaphuka okukhulu, ukuhlanza, okanye urhudo. |
| 👍 Ukuba iyaqhubeka okanye iyakhathaza, yazisa ugqirha wakho. | |
| Ukuqhinwa | Ubunzima bokuya kwindlu yangasese. |
| Umnqweno wokutya | Ukulahlekelwa yintliziyo. |
| Intloko ebuhlungu | Intloko ebuhlungu eqhelekileyo. |
| Uloyiko | Ukungcangcazela okungalawulekiyo kwamalungu omzimba, njengamalungu omzimba. |
Ukuba ufumana naziphi na ezinye iimpawu ezingaqhelekanga ezingakhankanywanga kolu luhlu, thetha nogqirha wakho ngazo.
Kuthekani ukuba ndisebenzisa i-overdose?
Ekubeni olu nyango lunikwa esibhedlele phantsi kweliso elibukhali leengcali zonyango, akukho mngcipheko mkhulu wokusebenzisa i-overdose. Nangona kunjalo, ukuba ufumana naziphi na iziphumo ezingalunganga, iqela lezonyango liya kwaziswa ngoko nangoko. Ukuba ufuna ingcebiso ngayo nayiphi na ityhefu, ungatsalela umnxeba iZiko loLwazi lweePoisons kwiSibhedlele sikaZwelonke saseColombo .
Umyalezo Wokuya Ekhaya
- I-Axicabtagene ciloleucel lunyango lwezakhi zofuzo oluphambili kakhulu olusebenzisa iiseli zakho zomzimba ukulwa nomhlaza.
- Ngaphambi kokuba ufumane olu nyango, kubalulekile ukuba uxelele ugqirha wakho ngembali yakho epheleleyo yempilo (kuquka isifo sentliziyo, usulelo, kunye ne-allergies).
- Emva konyango, lumka xa kukho iimpawu zosulelo ezifana nomkhuhlane, ukukhohlela, ukudideka, kunye nobunzima bokuphefumla. Ukuba oku kuyenzeka, funa ingcebiso kagqirha ngoko nangoko.
- Kuphephe ukuqhuba imoto nokwenza imisebenzi efuna ingqalelo kuba ukozela kunye nesiyezi zinokwenzeka ngexesha lonyango.
- Olu lunyango olulungiselelwe wena ngokukodwa. Ukuba unemibuzo okanye iinkxalabo malunga noku, ungathandabuzi ukuthetha nogqirha wakho.
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