Umntu othile kusapho lwakho, mhlawumbi umama wakho othandekayo, utata, umakhulu okanye umakazi, usenokuba unesifo sika-Alzheimer. Okanye mhlawumbi unomdla wokufunda okungakumbi ngesi sifo. Isifo sika-Alzheimer sesona sifo sixhaphakileyo se-dementia, imeko apho izakhono zokucinga ezifana nenkumbulo, izakhono zokusombulula iingxaki, kunye nolwimi zilahleka kancinci kancinci. Oku kunokwenza kube nzima ukwenza imisebenzi yemihla ngemihla.
Eyona nto ibangela umngcipheko omkhulu wesifo se-Alzheimer kukwaluphala. Nangona amayeza akhoyo ngoku anokulawula iimpawu ukuya kuthi ga kwinqanaba elithile, awanakumisa ngokupheleleyo esi sifo. Yiyo loo nto abaphandi bekhangela unyango olutsha olunokunciphisa ukuqhubela phambili kwesi sifo. Namhlanje, siza kuthetha ngezimbini zezi ndlela zonyango, ukuvuselela ubuchopho. Ngamafutshane, olu nyango lusebenzisa amaza ombane okanye emagnethi "ukuvula" okanye "ukucima" umsebenzi weendawo ezithile zobuchopho.
Yintoni unyango lwe-rTMS (Repetitive Transcranial Magnetic Stimulation)?
Olu lolunye lonyango olutsha oluvavanywayo kwizigulana ze-Alzheimer's. Lubandakanya ukusebenzisa imagnethi yangaphandle ukwenza indawo ethile yengqondo isebenze, ngaphandle kotyando. Lubizwa ngokuba "luphindaphindwayo" kuba unyango lwenziwa iintsuku ezintlanu ngeveki, yonke imihla kangangeeveki ezine ukuya kwezintandathu.
Khawucinge nje uhleli kwisitulo esiqhelekileyo. Ugqirha ubeka i-electromagnetic coil phezu kwentloko yakho. Xa isebenza, kuvakala ngathi i-tukanawak encinci ibetha ebunzini lakho ngesandi esithi "click" "click" esihlala imizuzwana embalwa. Ayifuni i-anesthesia (eyenza intloko yakho ibe nentlungu). Ekubeni ingeyotyando, ingenziwa eofisini kagqirha okanye eklinikhi.
Akucaci ngokupheleleyo ukuba i-rTMS isebenza njani ngokwenene kwizigulana ze-Alzheimer. Abaphandi bakholelwa ukuba ukuvuselela ingqondo ngale ndlela kunokukhawulezisa okanye kunciphise umsebenzi wobuchopho onxulumene nenkumbulo nokucinga.
Iphumelele kangakanani le nto?
Impumelelo yonyango lwe-rTMS ixhomekeke kwizinto ezininzi. Umzekelo, ukuvuselela okungaphantsi koxinzelelo lwengqondo kubonisiwe ukuba kunciphisa umsebenzi wobuchopho, ngelixa ukuvuselela okungaphezulu koxinzelelo lwengqondo kubonisiwe ukuba kuyandisa. Kwakhona, indawo yobuchopho ejoliswe kuyo unyango kunye nawaphi na amanye amayeza isigulane esiwasebenzisayo anokuchaphazela iziphumo.
Ngokubanzi, ukuvuselela rhoqo kuye kwabonakala kusebenza ngakumbi kubantu abane-dementia engephi kunabo bane-dementia enzulu. Ngamanye amaxesha, iziphumo ezilungileyo zibonakala kwangoko emva konyango, kodwa kwabanye abantu, kungathatha ukuya kwiiveki ezi-6 ukubona iziphumo. Ezi zibonelelo zinokuhlala iinyanga ezi-3 okanye ngaphezulu.
Ngamanye amaxesha olu nyango lwe-rTMS luhlobo loqeqesho lokuqonda kwengqondo.Kwenziwa kunye. Oko kukuthi, ukubonelela ngemisebenzi eyahlukeneyo kunye nokuzilolonga ukuphucula ukusebenza kwengqondo. Xa ezi zinto zimbini zenziwe kunye, kufunyenwe iziphumo ezingcono, ingakumbi kwizigulana ze-Alzheimer ezingephi ukuya kweziphakathi.
Okubalulekileyo kukuba, malunga nesiqingatha sezigulane ze-Alzheimer's zinengxaki yokudakumba. I-rTMS lunyango oluvunyiweyo yi-FDA lokudakumba. Ke ngoko, kunzima ukwahlula ukuba inzuzo yonyango lwe-rTMS kwizigulane ze-Alzheimer's ibangelwa sisifo sokwenyani okanye kukudakumba okuhambelana naso.
| Iziphumo ebezingalindelekanga kunye neengxaki zonyango lwe-rTMS | Inkcazo |
|---|---|
| Iziphumo ebezingalindelekanga eziqhelekileyo | Ukungakhululeki kwindawo eneemagnethi, ukurhawuzelela emhlathini, entlokweni, okanye ebusweni, intloko ebuhlungu, kunye nesiyezi zinokwenzeka. |
| Iziphumo ebezingalindelekanga ezinzulu kodwa ezingaqhelekanga | Ukuxhuzula kusenokungenzeki rhoqo. Akukabikho nto ingako eyaziwayo ngemiphumo emibi yexesha elide. |
| Iingxaki ezibangelwa ziingxaki | Ngokutsho kwabanye abaphandi, kukho inkxalabo yokuba ukuvuselela rhoqo kunokusenza sibe mandundu isifo se-Alzheimer. Kufuneka uphando olongezelelekileyo ngale nto. |
Yintoni iDeep Brain Stimulation (DBS)?
Ngokungafaniyo ne-rTMS, i-DBS lunyango olungenalusini olufuna utyando lobuchopho. Eli linyathelo elikhulu phambili. Kolu tyando, kufakwa ii-electrode ezimbini engqondweni yakho. Njenge-pacemaker, iijenereyitha ezimbini ezincinci ezilawula ezi electrode zifakwa phantsi kwesikhumba sesifuba sakho.
Ngaphambi kotyando, uza kwenziwa i-MRI scan yentloko yakho. Uza kube uvukile ngexesha lotyando. Ungakhathazeki, intloko yakho iza kuba ne-numbness (i-local anesthetic) ukuze ungabi nantlungu. Ngenxa yokuba ingqondo ayiziva iintlungu, ugqirha angasebenzisa imifanekiso ye-MRI ukubeka ii-electrode kwindawo efanelekileyo. Emva koko, uza kufakwa phantsi kwe-anesthesia eqhelekileyo kwaye ijenereyitha kunye neengcingo ezizidibanisa nee-electrode ezikwingqondo yakho ziya kufakwa esifubeni sakho. Emva kotyando, esi sixhobo siya kubonelela ngokukhuthaza okuqhubekayo kwingqondo yakho.
Unyango lwe-DBS lwaqala ukusetyenziswa ukunyanga iimpawu zesifo sikaParkinson, ezinje ngokungcangcazela kunye nokuqina. Kwakusemva kokuba esinye isigulana esafumana unyango lwe-DBS lokutyeba kakhulu sibonakalise ukuphucuka kwinkumbulo apho abaphandi baqala ukuphanda ukuba ingaba ingasetyenziselwa na isifo sika-Alzheimer.
Iphumelele kangakanani le nto?
Izifundo zokuqala zibonisa ukuba i-DBS lunyango oluthembisayo. Nangona kunjalo, impumelelo yayo ixhomekeke kwinqanaba lesifo kunye nesicwangciso sonyango (indawo yobuchopho ekujoliswe kuyo, amandla okukhuthaza).
Ngokubanzi, unyango lwe-DBS lusebenza kakhulu xa lusetyenziswa kwizigaba zokuqala zesifo (i-Alzheimer's yasekuqaleni) . Abantu abafunyaniswa emva kweminyaka engama-65 (ekuqaleni kwexesha) banokuzuza, oko kuthetha ukuba esi sifo sinokucothisa ukuqhubela phambili kwaso. Kodwa okumangalisayo kukuba, abantu abafunyaniswa ngaphambi kweminyaka engama-65 (ekuqaleni kwexesha) ababonanga nzuzo ingako kolu nyango.
| Iziphumo ebezingalindelekanga kunye neengxaki zonyango lwe-DBS | |
|---|---|
| Iingxaki ezinxulumene notyando | |
| Utyando lunokubangela ukopha, usulelo, kunye nokungasebenzi kakuhle kwezixhobo zesifuba. | |
| Iziphumo ebezingalindelekanga ezinxulumene nokukhuthaza | |
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| Ezinye iziphumo ebezingalindelekanga ezinokubakho | |
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Ezinye iziphumo ebezingalindelekanga (intloko ebuhlungu, urhudo, ukuhlanza) ziya kuphela ngokuhamba kwexesha, kodwa kubalulekile ukukhumbula ukuba i-DBS lunyango oluyingozi.
Umyalezo Wokuya Ekhaya
- Isifo sika-Alzheimer sisifo esiqhubekekayo. Nangona amayeza akhoyo ngoku ekwazi ukulawula iimpawu, awanakunyanga esi sifo.
- I-rTMS yindlela yokuvuselela ubuchopho engeyoyotyando, engenabungozi bungako, enokuba luncedo kubantu abakwinqanaba lokuqala lesi sifo, kodwa isesekwinqanaba lophando.
- I-DBS lunyango olunzima nolunobungozi olufuna utyando lobuchopho. Isenokuba luncedo nakubanye abantu abakwinqanaba lokuqala lesi sifo, kodwa ayikasetyenziswa kakhulu okwangoku.
- Zombini ezi ndlela zonyango zisavavanywa kwisifo sika-Alzheimer kwaye azingonyango oluqhelekileyo olunikwa abantu.
- Eyona nto ibalulekileyo kukuba ukuba umntu kusapho lwakho unesifo i-Alzheimer, ngaphambi kokuba uthathe isigqibo ngalo naluphi na unyango, thetha nogqirha wakho ngononophelo kwaye uqonde ukuba yeyiphi eyona ifanelekileyo kwimeko yesigulana.
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