Kukho izifo ekunzima ukuzilawula ngamayeza aqhelekileyo. Ingakumbi iimeko ezifana ne-arthritis ezibangelwa ziingxaki ezithile kwinkqubo yethu yokuzikhusela komzimba, okanye ezinye izifo ezingaqhelekanga ezibangela umkhuhlane rhoqo, ziwela kolu luhlu. Ngoko ke, ngamaxesha anje, oogqirha basebenzisa amayeza akhethekileyo nanamandla. Elinye lamayeza yiCanakinumab. Eli linikwa njengesitofu sokugonya.
Yintoni iCanakinumab?
Ngamafutshane, i-canakinumab liyeza elitshintsha indlela amasosha omzimba wethu asebenza ngayo ukuya kuthi ga kwinqanaba elithile kwaye lilawula iimpawu. Ayilonyango, kodwa inokukunceda ukulawula isifo kwaye uphile ubomi obuqhelekileyo.
Eli yeza lisetyenziswa kakhulu kwezi meko zilandelayo:
- Ezinye iintlobo ze-arthritis ebantwaneni nakubantu abadala: Umzekelo, iimeko ezifana nesifo sikaStill.
- IiSindromes zeFever ezingaqhelekanga: Ezi zaziwa ngamagama antsonkothileyo. Umzekelo:
- Ii-Cryopyrin-Associated Periodic Syndromes (CAPS)
- Isifo sePeriodic Syndrome esinxulumene neTumor Necrosis Factor Receptor Associated Periodic Syndrome (TRAPS)
- Isifo se-Hyperimmunoglobulin D (HIDS)
- Umkhuhlane weMeditera wosapho (FMF)
Eyona nto ibalulekileyo kukuba yingcali kuphela ehlola imeko yakho enokugqiba ukuba isebenzise na eli yeza kwaye ithathe ixesha elingakanani.
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uqale olu nyango
Ekubeni eli liyeza elinamandla kakhulu, kubalulekile ukuba wazise ugqirha wakho ngembali yakho epheleleyo yempilo ngaphambi kokuba uqale unyango. Musa ukulityeshela, ucinga ukuba yinto encinci. Kuba kwanaloo nto incinci inokuchaphazela unyango lwakho.
| Xelela ugqirha wakho ukuba unayo nayiphi na kwezi meko zilandelayo: | Kutheni oko kubalulekile? |
|---|---|
| Usulelo lwangoku okanye lwakutshanje (umz., i-chickenpox, i-herpes, izilonda zomkhuhlane) | Ngenxa yokuba eli yeza linciphisa amajoni omzimba, usulelo lunokuba nzima ngakumbi. |
| Isifo sephepha , uvavanyo lolusu olubonisa ukuba kukho isifo sephepha, okanye ukudibana ngokusondeleyo nomntu onesifo sephepha. | Ngaphambi kokuba uqale amayeza, kufuneka uhlolwe isifo sephepha, kwaye ukuba kuyimfuneko, uqale unyango. |
| Ezinye iingxaki zenkqubo yomzimba yokuzikhusela , i-HIV okanye i-AIDS. | Kufuneka ulumke ngakumbi xa usebenzisa eli yeza kwiimeko ezinjalo. |
| Ukuba nembali yomhlaza . | Ugqirha wakho ufanele ukuba uyazi le nto. |
| Iimeko ezinje ngokubala okuphantsi kweeseli ezimhlophe zegazi . | Le meko inokuchaphazeleka ngakumbi ngamayeza. |
| Ukukhulelwa okanye ukuzama ukukhulelwa. | Thetha nogqirha wakho malunga nemiphumo yale mithi ngexesha lokukhulelwa. |
| Ukuncancisa umntwana. | Ufanele uxoxe nogqirha wakho ukuba ingaba iyeza liza kuyichaphazela na imveku ngobisi lwebele. |
| Ukuba usandula ukufumana ugonyo okanye ucwangciselwe ukulufumana kwixesha elizayo. | Ngokukodwa, imijovo yentsholongwane ephilayo ayinakuthatyathwa kunye nale yeza. |
| Ukuba ne-aleji kwamanye amayeza, ukutya okanye izinto ezithile. | Oku kubalulekile ukuqinisekisa ukuba une-allergy kwi-canakinumab okanye nakweyiphi na izithako zayo. |
Ulisebenzisa njani eli yeza?
Eli asiloyeza onokulithatha uye nalo ekhaya uze ulinike wena. Eli liyeza elingaphantsi kolusu. Lidla ngokunikezelwa ngugqirha okanye umongikazi oqeqeshiweyo esibhedlele okanye eklinikhi .
Ngaphambi konyango ngalunye, uya kunikwa incwadana yolwazi ekhethekileyo (iMedGuide) malunga nale yeza. Kubalulekile ukuyifunda nokuyiqonda ngononophelo ngalo lonke ixesha.
Ngaba eli yeza lifanele linikwe abantwana?
Kwezinye iimeko ezikhethiweyo, eli yeza linokunikwa abantwana abaneminyaka emi-2 ubudala. Nangona kunjalo, esi sigqibo senziwa ngugqirha wabantwana. Ukuba unika umntwana eli yeza, qiniseka ukuba uxoxa ngalo ngokupheleleyo nogqirha wakho.
Kuthekani ukuba ndithatha amayeza amaninzi kakhulu?
Oku akunakwenzeka ukuba kwenzeke kuba kunikwa esibhedlele. Nangona kunjalo, ukuba ucinga ukuba usele amayeza amaninzi kakhulu, fowunela iZiko loLwazi lweePoison kwiSibhedlele sikaZwelonke saseColombo ngoko nangoko okanye uye kwiYunithi yoNyango oluNgxamisekileyo (ETU) yesibhedlele esikufutshane.
Amanye amayeza anokusebenza kunye nale mayeza
Kubaluleke kakhulu ukuxelela ugqirha wakho ngawo onke amayeza owasebenzisayo (kuquka iivithamini kunye namayeza esintu), njengoko amanye amayeza anokuchaphazela eli.
| Musa ukuthatha i-canakinumab kunye nezi zinto konke konke. | |
|---|---|
| Amayeza ebhayoloji | Umzekelo: adalimumab, anakinra, certolizumab, etanercept, golimumab, infliximab |
| Izitofu zokugonya iintsholongwane eziphilayo | Umzekelo, iMasisi, iMumps, iRubella (MMR), ugonyo lweChickenpox |
| Xelela ugqirha wakho kuba kusenokubakho unxibelelwano phakathi kwezi zinto. | |
| Amanye amayeza athintela amajoni omzimba | i-abatacept, i-baricitinib, i-rilonacept, i-rituximab, i-sarilumab, i-tocilizumab, i-tofactinib |
| I-Warfarin | Iyeza elinikwa ukuthintela ukujiya kwegazi |
Izinto ekufuneka uzikhumbule xa usebenzisa amayeza
- Lumka kwiintsholongwane: Eli yeza lithintela amajoni akho omzimba, likwenze ube namathuba amaninzi okufumana izifo. Ngoko ke, ukuba ufumana iimpawu ezifana nomkhuhlane, ukubanda, umphimbo obuhlungu, ukukhwehlela, okanye impumlo egobhozayo , musa ukuzinyanga nje kuphela. Fowunela ugqirha wakho ngoko nangoko ukuze akunike ingcebiso. Zama ukuhlala kude nabantu abagulayo.
- Uvavanyo lweSifo sePhepha (TB): Uza kuvavanywa isifo sePhepha (TB) ngaphambi kokuba uqale unyango. Ukuba ugqirha wakho ukunike amayeza esifo sePhepha, kuya kufuneka uqale ukuwasela loo mayeza ngaphambi kokuba uqale i-canakinumab. Kwaye kuya kufuneka uwasele amayeza ixesha elipheleleyo elimiselweyo.
- Ulawulo lwezonyango: Ugqirha wakho uza kuqhubeka ekujonga imeko yakho ngelixa usela eli yeza. Uza kuyalela novavanyo lwegazi ukuba kuyimfuneko. Ukuba iimpawu zakho aziphucuki okanye azibi mandundu, xelela ugqirha wakho .
Zeziphi iziphumo ebezingalindelekanga endinokuzifumana?
Njengayo nayiphi na imithi, le inokuba nemiphumo emibi. Eminye iyingozi, eminye ixhaphakile. Into ebalulekileyo kukwazi oku kwaye uthathe amanyathelo ngokukhawuleza ukuba kuyimfuneko.
| Iziphumo ebezingalindelekanga ezinzulu ekufuneka uzixele kugqirha wakho ngoko nangoko | |
|---|---|
| Iimpendulo ze-allergy | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe okanye ulwimi. |
| Ubunzima bokuphefumla | Ukuphefumla nzima, ukuxinana kwesifuba. |
| Utshintsho kwisantya sentliziyo | Ukuziva ngathi intliziyo yakho ibetha ngokukhawuleza okanye ngendlela engaqhelekanga. |
| Ukudinwa okanye ukuquleka | Ukuziva unesizungu, ungenabomi, uyawa. |
| Iimpawu zosulelo | Umkhuhlane, ukubanda, ukukhohlela, umphimbo obuhlungu, iintlungu xa uchama. |
| Ukudumba kolusu, ukuba bomvu, okanye ukufudumala | Ingakumbi kwenye indawo ngaphandle kwendawo yokujova. |
| Iziphumo ebezingalindelekanga ezingezizo ezinzulu, kodwa ekufuneka zixelwe kugqirha wakho ukuba ziyaqhubeka: | |
| Urhudo | Intloko ebuhlungu |
| Isicaphucaphu nokuhlanza | Impumlo egobhozayo, njengomkhuhlane |
| Isiyezi | Intlungu, ukubomvu, okanye ukudumba okuncinci kwindawo yokutofa |
Olu luhlu alubandakanyi zonke iziphumo ebezingalindelekanga. Ukuba ufumana into engaqhelekanga, ungoyiki ukuthetha nogqirha wakho ngayo.
Umyalezo Wokuya Ekhaya
- I-Canakinumab sisitofu esinamandla esisetyenziselwa ukunyanga izifo ezinxulumene nomzimba ezifana ne-arthritis kunye nezinye izifo ezingaqhelekanga zokudumba.
- Ngaphambi kokuba uqale olu nyango, kubalulekile ukuba wazise ugqirha wakho ngazo zonke iimeko zakho zempilo kunye nawo onke amayeza owasebenzisayo.
- Eli yeza lonyusa umngcipheko wokosuleleka, ngoko ke soloko uqaphela iimpawu ezinje ngomkhuhlane, ukukhwehlela, kunye nomphimbo obuhlungu.
- Ukuba ufumana naziphi na iziphumo ebezingalindelekanga ezinzulu, ezinje ngobunzima bokuphefumla okanye iimpembelelo ezimbi ze-allergy, funa ingcebiso kagqirha ngoko nangoko.
- Hlala unxibelelana rhoqo nogqirha wakho. Musa ukulibazisa amayeza. Xoxa naye ngayo nayiphi na into ekuphazamisayo.
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