Ngaba wena okanye umntu omaziyo uxelelwe ngugqirha wakho ukuba aqale ukuthatha iyeza elibizwa ngokuba yiCobimetinib? Usenokuba uzive usoyika kwaye ungaqhelananga xa usiva eli gama. Oko kuqhelekile ngokwenene. Akumangalisi ukuba uzive ngolo hlobo malunga neyeza elinegama elitsha nelingaziwayo. Ngoko ke ungoyiki. Namhlanje, siza kuthetha ngokuba liyintoni eli yeza, lisebenza ntoni, kwaye kufuneka uqaphele ntoni xa ulisebenzisa, ngendlela elula onokuyiqonda.
Yintoni iCobimetinib?
Ngamafutshane, iCobimetinib liyeza elikhethekileyo elithintela ukukhula kweeseli zomhlaza. Lisetyenziswa kakhulu ukunyanga uhlobo lomhlaza wolusu olubizwa ngokuba yimelanoma .
Okukhethekileyo ngale nto kukuba "lunyango olujoliswe kulo." Oko kuthetha ukuba eli yeza alichaphazeli nje kuphela zonke iiseli emzimbeni. Endaweni yoko, lijolise kwiiproteni ezithile ezinceda iiseli zomhlaza zikhule kwaye zithintele ekwenzeni oko. Ngamanye amazwi, njengokuzama ukuvula ucango ngesitshixo esingalunganga, eli yeza liphazamisa inkqubo yokukhula kweeseli zomhlaza. Eli yeza likwafumaneka kwimarike phantsi kwegama elithi Cotellic .
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uthathe amayeza
Ngaphambi kokuba ugqirha wakho akunike eli yeza, kuya kufuneka abe nomfanekiso opheleleyo wempilo yakho. Ngoko ke, ukuba unenye yezi meko zidweliswe ngezantsi, qiniseka ukuba uxelele ugqirha wakho.
- Izifo zamehlo okanye ukuphazamiseka kokubona: Ukuba unesifo samehlo okanye utshintsho ekuboneni.
- Isifo sentliziyo: Ukuba unayo nayiphi na ingxaki yentliziyo.
- Umngcipheko wokopha: Ukuba unesifo sokopha okanye ukuba wopha rhoqo.
- Isifo sesibindi: Ukuba unesifo sesibindi.
- Intlungu okanye ubuthathaka bemisipha: Ukuba usoloko uneentlungu okanye ubuthathaka bemisipha.
- Iimeko zesikhumba okanye ubuthathaka besikhumba: Ukuba uneengxaki zesikhumba okanye ulusu lwakho lubuthathaka.
- Ii-Allergies: Ukuba une-allergies kweli yeza leCobimetinib, amanye amayeza, ukutya, okanye iidayi.
- Ukukhulelwa: Oku kubaluleke kakhulu ukuba ukhulelwe , uzama ukukhulelwa , okanye ukrokrela ukuba ukhulelwe .
- Ukuncancisa: Ukuba ungumama oncancisa umntwana wakho.
Indlela yokusebenzisa amayeza ngokuchanekileyo?
Indlela osebenzisa ngayo eli yeza ibaluleke kakhulu. Ufanele ulilandele kanye njengoko ugqirha ekuxelele.
- Sela le pilisi neglasi yamanzi.
- Ungayithatha ngaphambi okanye emva kokutya, kodwa ukuba uziva uphazamisekile esiswini, kungcono ukuyithatha kunye nokutya.
- Kubaluleke kakhulu: Ungaze uthathe eli yeza kunye nejusi yegrapefruit. Linokuchaphazela kakubi indlela elisebenza ngayo eli yeza.
- Sela amayeza ngexesha elimiselweyo nangexesha elimiselweyo. Musa ukuthatha ngaphezu komlinganiselo omiselweyo.
- Musa ukuyeka ukuthatha amayeza ngaphandle kwengcebiso kagqirha wakho.
Kuthekani ukuba ndiphoswa lidosi leyeza?
Ukuba uphoswe yidosi, okanye ukuba uyahlanza emva kokusela idosi, musa ukuthatha enye ipilisi ngelo xesha. Thatha ipilisi elandelayo ngexesha eliqhelekileyo. Ungaze uthathe idosi ephindwe kabini.
Kuthekani ukuba ndithatha amayeza amaninzi kakhulu?
Ukuba ucinga ukuba uthathe amayeza amaninzi kakhulu, fowunela iZiko loLwazi lwePoisons kwiSibhedlele sikaZwelonke saseColombo ngoko nangoko, okanye uye kwiYunithi yoNyango oluNgxamisekileyo (ETU) yesibhedlele esikufutshane.
Ezinye izinto ezinokusebenzisana nale mithi
Amanye amayeza owasebenzisayo anokusebenzisana neCobimetinib. Ngoko ke xelela ugqirha wakho ngawo onke amayeza owasebenzisayo (kuquka iivithamini, iimveliso zezityalo, kunye namayeza ezityalo). Lumka kakhulu kwezi zinto zilandelayo:
- Amayeza osulelo lwefungus: Umzekelo, `(ketoconazole)` kunye `(itraconazole)`.
- Amayeza okuxhuzula/ ukuxhuzula : Umzekelo `(carbamazepine)`, `(phenobarbital)`, `(phenytoin)`.
- Ezinye ii-antibiotics: ezifana ne-`(ciprofloxacin)`, `(erythromycin)`.
- Amanye amayeza: afana ne-`(efavirenz)`, `(rifampin)`.
- Iimveliso zezityalo: Imveliso yezityalo ebizwa ngokuba yiSt. John's Wort .
- Ijusi yegrapefruit .
Olu luhlu aluphelelanga, ngoko ke kungcono ukuxelela ugqirha wakho ngayo yonke into oyithathayo.
Izinto ekufuneka uzikhumbule xa usebenzisa amayeza
Ufanele unikele ingqalelo engakumbi emzimbeni wakho ngelixa usebenzisa eli yeza.
Ukuhlolwa rhoqo kwezonyango
Ugqirha uza kukuxelela ukuba uze ekliniki rhoqo. Uza kuyalela novavanyo lwegazi ukuze kujongwe inkqubela yonyango. Musa ukuziphosa ezi zinto.
Ukukhuselwa lilanga
Eli linqaku elibaluleke kakhulu. Xa usela eli yeza, ulusu lwakho lunokuba novakalelo elangeni (photosensitivity) . Khawuthelekelele, nokuba uphuma elangeni njengesiqhelo, emva kwexesha ulusu lwakho lunokuba bomvu, luzive ngathi luyatsha, kwaye lube namadyungudyungu. Ngenxa yoko:
- Ziphephe ilanga eliqatha kangangoko unako.
- Ukuba uphuma elangeni, nxiba impahla egquma umzimba wakho kakuhle.
- Qiniseka ukuba usebenzisa i-sunscreen .
- Musa ukusebenzisa izibane zelanga okanye iibhedi zokutshisa ilanga.
Ukukhulelwa kunye nokuncancisa
Le yinto ekufuneka uyikhumbule kwakhona.
Kuphephe ukukhulelwa ngelixa usela eli yeza kwaye kangangeeveki ezimbini emva kokuyeka iyeza. Linokubangela ingozi enkulu kusana olungekazalwa. Thetha nogqirha wakho ukuba uceba ukukhulelwa.
Kwakhona, musa ukuncancisa umntwana wakho ngelixa usebenzisa eli yeza kwaye kangangeeveki ezimbini emva kokuba uyekile.
Iziphumo ebezingalindelekanga ekufuneka uziqaphele
Njengayo nayiphi na iyeza, eli linokuba nemiphumo emibi. Amanye afuna ingqalelo ekhawulezileyo, ngelixa amanye exhaphakile.
| Imiphumela | Inkcazo kunye nendlela yokunikela ingqalelo |
|---|---|
| Ukuba ufumana ezi mpawu, xelela ugqirha wakho ngoko nangoko. | |
| Utshintsho lolusu | Ulusu luyadumba, luyaxobuka, lunamanxeba amaninzi. |
| Utshintsho lombono | Umbono ofipheleyo, amabala phambi kwamehlo, njl. |
| Ukubetha kwentliziyo ngokukhawuleza/ubunzima bokuphefumla | Ukuziva ukubetha kwentliziyo ngokukhawuleza, ukuqina kwesifuba, ukuphefumla kancinci. |
| Iimpawu zokopha | Igazi elikwisitulo okanye indle emnyama, umchamo obomvu okanye omdaka, ukuhlanza into efana nekofu egayiweyo, amabala abomvu eluswini, ukopha okungaqhelekanga okuvela empumlweni okanye kwiintsini. |
| Iimpawu zomonakalo wesibindi | Umchamo otyheli/omdaka omnyama, ukutyheli kwamehlo okanye ulusu, iintlungu kwicala eliphezulu lasekunene lesisu, ukungabi namdla wokutya, kunye nokuziva udiniwe. |
| Iimpawu zomonakalo wemisipha | Umchamo omnyama, ubunzima bokuchama, iintlungu eziqatha kwimisipha, kunye nokuziva ubuthathaka. |
| Ukudumba komzimba | Ukudumba kwiindawo ezifana namaqatha, iinyawo, nezandla. |
| Ezi zihlandlo azibalulekanga kangako, kodwa ukuba ziyaqhubeka, xelela ugqirha wakho. | |
| Urhudo | Ukuqunjelwa. |
| Ifiva | Ubushushu bomzimba. |
Umyalezo Wokuya Ekhaya
- I-Cobimetinib lunyango olujoliswe kulo lwe-melanoma, umhlaza wolusu.
- Musa ukusela ijusi yegrapefruit ngokupheleleyo ngelixa usebenzisa eli yeza.
- Xelela ugqirha wakho ngazo zonke ezinye iziyobisi (kuquka iivithamini kunye neemveliso zezityalo) ozisebenzisayo.
- Zikhusele elangeni ngelixa usela amayeza. Ukusebenzisa i-sunscreen kuyimfuneko.
- Kuphephe ukukhulelwa ngelixa usela ipilisi kwaye emva kweeveki ezimbini uyekile. Oku kubaluleke kakhulu.
- Ukuba ubona naziphi na iziphumo ebezingalindelekanga ezinje ngokutshintsha kombono, utshintsho olukhulu lolusu, ubunzima bokuphefumla, okanye ukopha okungaqhelekanga, yazisa ugqirha wakho ngoko nangoko.
- Ukuba unemibuzo okanye amathandabuzo, ungoyiki ukuthetha nogqirha wakho ngayo.
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