Ngaba amathambo akho nawo abuthathaka? Makhe sithethe ngeFibrous Dysplasia!

Ngaba wakha wacinga ukuba amathambo ethu ngamanye amaxesha anokubuthathaka aze akhule ngeendlela ezingaqhelekanga? Namhlanje siza kuthetha ngemeko yamathambo engaqhelekanga, kodwa kubalulekile ukuyazi. Ibizwa ngokuba yiFibrous Dysplasia . Usenokuba nale meko ngaphandle kweempawu. Ngoko masithethe ngayo ngokweenkcukacha ezithe vetshe, akunjalo?

Yintoni iFibrous Dysplasia?

Ngamafutshane, i-fibrous dysplasia yimeko engaqhelekanga apho izicubu ezingaqhelekanga (ezifana nesilonda) zikhula emizimbeni yethu endaweni yezicubu eziphilileyo zamathambo. Le zicubu intsha ayinamandla njengethambo lokwenyani. Ngenxa yoko , amathambo aba buthathaka kwaye athambekele ekuqhekekeni (ukuqhekeka).

Le meko inokuchaphazela naliphi na ithambo emzimbeni, kodwa idla ngokuchaphazela:

• Ukuya kwithambo lethanga (elona thambo likhulu kwinxalenye ephezulu yomlenze wethu - `i-femur`)
• Kwithambo lesifuba (ithambo elingaphantsi kwedolo lomlenze - `tibia`)
• Ukuya kwiimbambo
• Intloko (kuquka amathambo obuso)
• Ithambo lengalo ephezulu (ihumerus)

Iindaba ezimnandi zezokuba lo mhlaza awungomhlaza (ongengomhlaza) . Oko kuthetha ukuba awuyi kusasazeka kwamanye amathambo emzimbeni. Oko kuyanceda kancinci, akunjalo?

Ngaba kukho iintlobo ze-fibrous dysplasia?

Ewe, oogqirha bayahlula le meko ibe ziintlobo ezimbini eziphambili, kuxhomekeke kwinani lamathambo achaphazelekileyo:

1. I-Monostotic fibrous dysplasia: Oku kuchaphazela ithambo elinye kuphela.

2. I-Polyostotic fibrous dysplasia: Oku kuchaphazela amathambo aliqela .

Ngamanye amaxesha, ukuba unesifo esingaqhelekanga esibizwa ngokuba yi-``McCune-Albright syndrome``, usenokuba ne-polyostotic fibrous dysplasia. Esi sifo sichaphazela amathambo ethu, ulusu, kunye ne-``endocrine system``` (inkqubo elawula iihomoni).

Zithini iimpawu zoku?

Ayingabo bonke abantu abane-fibrous dysplasia abaneempawu. Yiyo loo nto kunzima ukuyicinga. Abanye abantu bafumanisa ukuba banale meko ngengozi xa bethathwa i-X-ray ngesinye isizathu.

Nangona kunjalo, kwabo bathe baba neempawu, oku kulandelayo kunokwenzeka:

• Ukuqhekeka kwamathambo rhoqo: Nokuba ukuwa okuncinci kunokwaphula ithambo.
• Intlungu yamathambo: Usenokuva intlungu ebukhali kwithambo elichaphazelekayo. Le ntlungu inokwanda kancinci kancinci kwaye ngamanye amaxesha ibe qatha.
• Utshintsho kwimilo yamathambo: Amathambo asenokubonakala edumbile okanye ekhule ngendlela engaqhelekanga.
• Ukudumba okungenabuhlungu kwiimbambo: Abanye abantu bafumana ukudumba okufana neqhuma kwindawo yembambo, kodwa akubuhlungu.
• I-Scoliosis: Umqolo unokugoba uye kwelinye icala.
• Amehlo avele ngaphandle:Ukuba amathambo ekhakayi achaphazelekile, amehlo anokubonakala ngathi aphuma phambili.
• Ukushukuma kwemihlathi: Ukuba amathambo emihlathi achaphazelekile, umhlathi unokushukuma uye kwelinye icala.
• Amazinyo ahamba okanye angalunganga: Amazinyo asenokuhamba okanye angahambelani kakuhle ngenxa yotshintsho kwithambo lomhlathi.
• Ukuxinana kwempumlo: Ukuba amathambo obuso ayachaphazeleka, unokufumana ukuxinana kwempumlo rhoqo.

Ngokuqhelekileyo, abo bachaphazelekileyo ngamathambo amaninzi (i-polyostotic) baneengxaki ezininzi kunabo bachaphazelekileyo ngamathambo elinye kuphela (i-monostotic).

Kutheni kukho i-fibrous dysplasia?

Oku kunzima kancinci. Le meko ibangelwa kukuguquka okungacwangciswanga kwijini ebizwa ngokuba yi-`GNAS1` emizimbeni yethu emva kokuba sikhulelwe esibelekweni. Olu tshintsho lwejini luchaphazela iiseli zethu ezibizwa ngokuba yi-`osteoblasts`. Ii-Osteoblast luhlobo olukhethekileyo lweeseli ezinceda amathambo ethu akhule aze akheke. Ngoko ke, xa umsebenzi wezi seli uphazamiseka, kuvela izicubu ezingaqhelekanga ezine-fibrous.

Kubaluleke kakhulu: Oogqirha abakayazi kakuhle ukuba kutheni olu tshintsho lwemfuza lwenzeka. Kwakhona, aluyonto yemfuza. Oko kuthetha ukuba nokuba unale meko, abantwana bakho abayi kuyizuza njengelifa. Asikuko ukuba unetyala okanye nantoni na. Ngoko ke ungakhathazeki ngayo, kulungile?

Zeziphi iingxaki ezinokubangela oku?

Ingxaki ephambili ebonwa kwi-fibrous dysplasia kukuba amathambo aphuka lula, kuba izicubu ezisandul’ ukwakheka azinamandla njengethambo lokwenyani.

Ukongeza, ukuba le meko ichaphazela amathambo ajikeleze amehlo okanye amathambo ajikeleze iindlebe, ukuva okanye ukubona kunokubangela ukuphazamiseka . Ngoko ke, kubalulekile ukuba uqaphele iimpawu ezinjalo.

Oogqirha bayifumana njani le nto?

Ukuba unentlungu yamathambo okanye ezinye iimpawu ezingaqhelekanga, kufuneka ubone ugqirha. Ugqirha uza kuqala akubuze ngeempawu zakho, njengokuthi sele zikho ixesha elingakanani. Emva koko uza kwenza uvavanyo lomzimba, ingakumbi ejonge kufutshane nendawo apho kukho khona intlungu.

Ukongeza, kunokwenzeka ukwenza iimvavanyo ezifana nezi:

• Uvavanyo lwegazi nomchamo: Olu vavanyo lwenziwa ukuze kubonwe ukuba amanqanaba athile eeenzyme aphakanyisiwe na. Ukuba aphakanyisiwe, oku kunokunika ingcaciso malunga nokukhula okungaqhelekanga kwezicubu ezine-fibrous.
• Uvavanyo lomfanekiso:
• Ii-X-reyi: Ezi zinokubona izicwili ezingaqhelekanga, ukwaphuka, kunye notshintsho kwimo yamathambo.
• Ii-CT scans kunye nee-MRIs: Ezi zinokuvelisa imifanekiso ecacileyo neneenkcukacha ezingaphezulu kune-X-ray. Zinceda ekufundeni imeko yamathambo ngokunzulu ngakumbi.
• Uvavanyo lwe-biopsy:Ngamanye amaxesha, ukuba ugqirha unamathandabuzo, uya kuthatha iqhekeza elincinci kakhulu lezicubu ezingaqhelekanga okanye izicubu zethambo eziphilileyo aze alihlole phantsi kwe-microscope. Oku kubizwa ngokuba yi-biopsy. Oku kuqinisekisa ngokuqinisekileyo ukuba isifo sikhona.

Iphathwa njani i-fibrous dysplasia?

Iindlela zonyango zixhomekeke kwiimpawu zakho, ubukhali bemeko, kunye nendlela echaphazela ngayo ubomi bakho. Asinguye wonke umntu ofuna uhlobo olufanayo lonyango.

Iindlela eziphambili zonyango zezi zilandelayo:

1. Ukuqwalaselwa: Ukuba awunazo iimpawu, okanye ukuba iimpawu zakho azikho qatha, ugqirha wakho usenokungakuniki naluphi na unyango oluthile, kodwa unokuwajonga amathambo akho ngokuhlolwa rhoqo (ii-aphoyintimenti zokulandelela). Oku kukujonga ukuba kukho utshintsho na.

2. Amayeza: Amayeza athile (umz. i-bisphosphonates) anokunikwa ukuqinisa amathambo, ukunciphisa umngcipheko wokuqhekeka kwamathambo, kunye nokulawula iintlungu.

3. Ukuxhoma: Ngamanye amaxesha unokucelwa ukuba unxibe izixhasi zokuxhasa amathambo abuthathaka, uwancede akhule kakuhle, kwaye uthintele ukukhubazeka.

4. Utyando:

• Yomeleza amathambo aqhekeka rhoqo.
• Lungisa amathambo aphukileyo kakhulu.
• Ukuba imilo yamathambo igqwethekile, yilungise.
• Ngamanye amaxesha, kusenokufuneka kwenziwe "ukufakelwa amathambo." Oku kuthetha ukuthatha iqhekeza lethambo eliphilileyo kwelinye ilungu lomzimba uze ulifake kwithambo elichaphazelekayo.

Ndifanele ndimbone nini ugqirha?

Ukuba uneentlungu zamathambo ezingapheliyo, qiniseka ukuba ubonana nogqirha. Isenokungabi yi-fibrous dysplasia, kodwa kubalulekile ukufumana unobangela.

Ukuba sele uyazi ukuba une-fibrous dysplasia, bona ugqirha wakho ukuba:

• Ukuba uziva ngathi iimpawu zakho ziya zisiba mandundu .
• Ukuba uvakalelwa kukuba unyango olufumanayo aluncedi .

Kubalulekile: Ngenxa yokuba i-fibrous dysplasia iwenza buthathaka amathambo, ukuba uyawa, ubethe into enzima, okanye ufumene ingozi yemoto, yiya kwigumbi likaxakeka lesibhedlele esikufutshane ngoko nangoko. Kukho umngcipheko omkhulu wokwaphuka kwamathambo.

Ukuba ndine-fibrous dysplasia, ndimele ndilindele ntoni?

Kunzima ukunika impendulo enye kulo mbuzo, kuba i-fibrous dysplasia ichaphazela wonke umntu ngeendlela ezahlukeneyo. Abanye abantu banokuphila ngaphandle kweengxaki ezinkulu. Abanye banokufuna ukuqaphela ngakumbi baze bafumane unyango.

Kodwa into enye eqinisekileyo: i-fibrous dysplasia yimeko engapheliyo.Oko kuthetha ukuba asisosifo esinokunyangeka ngokupheleleyo, kodwa kukho unyango olunokunceda ekunciphiseni impembelelo yaso ebomini bakho.

Xa ufumanisa ukuba unale meko, unokumangaliswa kwaye ukhathazeke kancinci. Yinto eqhelekileyo leyo. Kodwa khumbula, awuwedwa. Thetha ngokukhululekileyo ngale nto nogqirha wakho. Uza kukuchazela into omawuyilindele kunye nonyango olufanelekileyo kuwe.

Okokugqibela, izinto ekufuneka uzikhumbule (Umyalezo Wokuya Ekhaya)

Kulungile, masikhumbule la manqaku njengesishwankathelo se-fibrous dysplasia esithethe ngayo namhlanje:

• I-Fibrous dysplasia sisifo samathambo esingaqhelekanga.
• Kule ngxaki , kwakheka izicubu ezibuthathaka nezine-fibrous endaweni yethambo eliphilileyo.
• Oku kunokubangela ukuba amathambo aphuke lula.
• Abanye abantu basenokungabi nazo naziphi na iimpawu .
• Lo asingomhlaza, kwaye awuzuzisi ilifa.
• Nangona kungekho nyango lupheleleyo, kukho unyango lokulawula iimpawu nokunciphisa impembelelo ebomini.
• Ukuba unentlungu emathanjeni okanye ezinye iimpawu ezirhanelekayo, qiniseka ukuba ucela ingcebiso kugqirha.

Ndiyathemba ukuba olu lwazi luza kukunceda. Ukuba uneminye imibuzo malunga noku, ungathandabuzi ukubuza ugqirha wakho. Hlala usempilweni!

I- Fibrous dysplasia, isifo samathambo, ukwaphuka kwamathambo, iintlungu zamathambo, i-GNAS1 gene, impilo yamathambo, izifo ezingaqhelekanga